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ONTOLOGY REPORT - ANNOTATIONS


Term:2,5-hexanedione
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Accession:CHEBI:85014 term browser browse the term
Definition:A diketone that is hexane substituted by oxo groups at positions 2 and 5. It is a toxic metabolite of hexane and of 2-hexanone
Synonyms:related_synonym: 1,2-Diacetylethane;   2,5-Diketohexane;   2,5-Hexadione;   Acetonyl acetone;   CH3COCH2CH2COCH3;   Formula=C6H10O2;   InChI=1S/C6H10O2/c1-5(7)3-4-6(2)8/h3-4H2,1-2H3;   InChIKey=OJVAMHKKJGICOG-UHFFFAOYSA-N;   NSC 7621;   SMILES=CC(=O)CCC(C)=O;   acetonylacetone;   alpha,beta-diacetylethane;   hexane-2,5-dione
 xref: CAS:110-13-4
 xref_mesh: MESH:C011269
 xref: MetaCyc:CPD-15521;   PMID:1781736;   PMID:24634916;   PMID:25549948;   Reaxys:506525;   Wikipedia:Hexane-2\,5-dione


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2,5-hexanedione term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABI2 abl interactor 2 JBrowse link 2 203,325,013 203,432,169 RGD:6480464
G ACO2 aconitase 2 JBrowse link 22 41,468,756 41,528,979 RGD:6480464
G ALOX15B arachidonate 15-lipoxygenase type B JBrowse link 17 8,039,040 8,049,134 RGD:6480464
G ANGPTL4 angiopoietin like 4 JBrowse link 19 8,364,129 8,374,373 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L14 BCL2 like 14 JBrowse link 12 12,049,849 12,099,695 RGD:6480464
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:6480464
G BFAR bifunctional apoptosis regulator JBrowse link 16 14,632,831 14,669,236 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CCDC171 coiled-coil domain containing 171 JBrowse link 9 15,552,874 16,062,431 RGD:6480464
G CCDC191 coiled-coil domain containing 191 JBrowse link 3 113,964,137 114,056,613 RGD:6480464
G CDIN1 CDAN1 interacting nuclease 1 JBrowse link 15 36,579,611 36,810,248 RGD:6480464
G CEP112 centrosomal protein 112 JBrowse link 17 65,635,537 66,192,133 RGD:6480464
G CFAP221 cilia and flagella associated protein 221 JBrowse link 2 119,544,392 119,660,321 RGD:6480464
G CKMT1B creatine kinase, mitochondrial 1B JBrowse link 15 43,592,857 43,599,406 RGD:6480464
G CLCA2 chloride channel accessory 2 JBrowse link 1 86,424,144 86,456,553 RGD:6480464
G CLU clusterin JBrowse link 8 27,596,917 27,614,700 RGD:6480464
G CTXN1 cortexin 1 JBrowse link 19 7,924,491 7,926,135 RGD:6480464
G DCN decorin JBrowse link 12 91,140,484 91,182,817 RGD:6480464
G DENND1A DENN domain containing 1A JBrowse link 9 123,379,654 123,930,158 RGD:6480464
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 JBrowse link 1 77,979,158 78,017,964 RGD:6480464
G DPP7 dipeptidyl peptidase 7 JBrowse link 9 137,110,540 137,117,980 RGD:6480464
G DPYSL2 dihydropyrimidinase like 2 JBrowse link 8 26,514,031 26,658,175 RGD:6480464
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:6480464
G ERC1 ELKS/RAB6-interacting/CAST family member 1 JBrowse link 12 990,030 1,495,933 RGD:6480464
G FASLG Fas ligand JBrowse link 1 172,659,008 172,666,876 RGD:6480464
G FASN fatty acid synthase JBrowse link 17 82,078,338 82,098,303 RGD:6480464
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 161,215,295 161,219,245 RGD:6480464
G GADD45A growth arrest and DNA damage inducible alpha JBrowse link 1 67,685,201 67,688,334 RGD:6480464
G GAS2 growth arrest specific 2 JBrowse link 11 22,627,758 22,885,930 RGD:6480464
G GFAP glial fibrillary acidic protein JBrowse link 17 44,903,159 44,915,552 RGD:6480464
G GHSR growth hormone secretagogue receptor JBrowse link 3 172,443,291 172,448,456 RGD:6480464
G GLUD1 glutamate dehydrogenase 1 JBrowse link 10 87,050,202 87,094,843 RGD:6480464
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:6480464
G GSN gelsolin JBrowse link 9 121,201,483 121,332,844 RGD:6480464
G GSTM5 glutathione S-transferase mu 5 JBrowse link 1 109,711,751 109,718,268 RGD:6480464
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 67,583,812 67,586,653 RGD:6480464
G HDGFL1 HDGF like 1 JBrowse link 6 22,569,566 22,571,666 RGD:6480464
G HSPA1B heat shock protein family A (Hsp70) member 1B JBrowse link 6 31,827,738 31,830,254 RGD:6480464
G IER3 immediate early response 3 JBrowse link 6 30,743,199 30,744,547 RGD:6480464
G IFT81 intraflagellar transport 81 JBrowse link 12 110,124,335 110,218,793 RGD:6480464
G IGFBP3 insulin like growth factor binding protein 3 JBrowse link 7 45,912,245 45,921,272 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G INA internexin neuronal intermediate filament protein alpha JBrowse link 10 103,277,138 103,290,346 RGD:6480464
G ITGAM integrin subunit alpha M JBrowse link 16 31,259,975 31,332,877 RGD:6480464
G ITGB1 integrin subunit beta 1 JBrowse link 10 32,900,318 32,958,230 RGD:6480464
G KIAA0930 KIAA0930 JBrowse link 22 45,192,244 45,240,894 RGD:6480464
G KIAA1328 KIAA1328 JBrowse link 18 36,828,817 37,232,140 RGD:6480464
G KIF6 kinesin family member 6 JBrowse link 6 39,329,990 39,725,423 RGD:6480464
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 54,657,928 54,740,715 RGD:6480464
G LOXL1 lysyl oxidase like 1 JBrowse link 15 73,926,462 73,952,137 RGD:6480464
G LRRC6 leucine rich repeat containing 6 JBrowse link 8 132,570,416 132,685,039 RGD:6480464
G LRRC69 leucine rich repeat containing 69 JBrowse link 8 91,102,619 91,219,254 RGD:6480464
G LYZ lysozyme JBrowse link 12 69,348,381 69,354,234 RGD:6480464
G MACROD1 mono-ADP ribosylhydrolase 1 JBrowse link 11 63,998,554 64,166,652 RGD:6480464
G MAP1A microtubule associated protein 1A JBrowse link 15 43,517,608 43,531,611 RGD:6480464
G MAP1B microtubule associated protein 1B JBrowse link 5 72,107,475 72,209,565 RGD:6480464
G MAP2 microtubule associated protein 2 JBrowse link 2 209,424,047 209,734,118 RGD:6480464
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 5 56,815,543 56,896,152 RGD:6480464
G MAPT microtubule associated protein tau JBrowse link 17 45,894,382 46,028,334 RGD:6480464
G MDH1 malate dehydrogenase 1 JBrowse link 2 63,588,963 63,607,197 RGD:6480464
G MFAP3L microfibril associated protein 3 like JBrowse link 4 169,986,602 170,033,003 RGD:6480464
G MIR10B microRNA 10b JBrowse link 2 176,150,303 176,150,412 RGD:6480464
G MIR1224 microRNA 1224 JBrowse link 3 184,241,405 184,241,489 RGD:6480464
G MIR125A microRNA 125a JBrowse link 19 51,693,254 51,693,339 RGD:6480464
G MIR130B microRNA 130b JBrowse link 22 21,653,304 21,653,385 RGD:6480464
G MIR134 microRNA 134 JBrowse link 14 101,054,687 101,054,759 RGD:6480464
G MIR155 microRNA 155 JBrowse link 21 25,573,980 25,574,044 RGD:6480464
G MIR183 microRNA 183 JBrowse link 7 129,774,905 129,775,014 RGD:6480464
G MIR193A microRNA 193a JBrowse link 17 31,559,996 31,560,083 RGD:6480464
G MIR194-2 microRNA 194-2 JBrowse link 11 64,891,355 64,891,439 RGD:6480464
G MIR196A1 microRNA 196a-1 JBrowse link 17 48,632,490 48,632,559 RGD:6480464
G MIR196A2 microRNA 196a-2 JBrowse link 12 53,991,738 53,991,847 RGD:6480464
G MIR199A2 microRNA 199a-2 JBrowse link 1 172,144,535 172,144,644 RGD:6480464
G MIR200C microRNA 200c JBrowse link 12 6,963,699 6,963,766 RGD:6480464
G MIR202 microRNA 202 JBrowse link 10 133,247,511 133,247,620 RGD:6480464
G MIR206 microRNA 206 JBrowse link 6 52,144,349 52,144,434 RGD:6480464
G MIR208A microRNA 208a JBrowse link 14 23,388,596 23,388,666 RGD:6480464
G MIR20A microRNA 20a JBrowse link 13 91,351,065 91,351,135 RGD:6480464
G MIR21 microRNA 21 JBrowse link 17 59,841,266 59,841,337 RGD:6480464
G MIR212 microRNA 212 JBrowse link 17 2,050,271 2,050,380 RGD:6480464
G MIR22 microRNA 22 JBrowse link 17 1,713,903 1,713,987 RGD:6480464
G MIR223 microRNA 223 JBrowse link X 66,018,870 66,018,979 RGD:6480464
G MIR224 microRNA 224 JBrowse link X 151,958,578 151,958,658 RGD:6480464
G MIR27A microRNA 27a JBrowse link 19 13,836,440 13,836,517 RGD:6480464
G MIR27B microRNA 27b JBrowse link 9 95,085,445 95,085,541 RGD:6480464
G MIR300 microRNA 300 JBrowse link 14 101,041,363 101,041,445 RGD:6480464
G MIR30A microRNA 30a JBrowse link 6 71,403,551 71,403,621 RGD:6480464
G MIR32 microRNA 32 JBrowse link 9 109,046,229 109,046,298 RGD:6480464
G MIR320A microRNA 320a JBrowse link 8 22,244,966 22,245,037 RGD:6480464
G MIR323A microRNA 323a JBrowse link 14 101,025,732 101,025,817 RGD:6480464
G MIR326 microRNA 326 JBrowse link 11 75,335,092 75,335,186 RGD:6480464
G MIR330 microRNA 330 JBrowse link 19 45,638,994 45,639,087 RGD:6480464
G MIR331 microRNA 331 JBrowse link 12 95,308,420 95,308,513 RGD:6480464
G MIR339 microRNA 339 JBrowse link 7 1,022,933 1,023,026 RGD:6480464
G MIR33A microRNA 33a JBrowse link 22 41,900,944 41,901,012 RGD:6480464
G MIR345 microRNA 345 JBrowse link 14 100,307,859 100,307,956 RGD:6480464
G MIR370 microRNA 370 JBrowse link 14 100,911,139 100,911,213 RGD:6480464
G MIR375 microRNA 375 JBrowse link 2 219,001,645 219,001,708 RGD:6480464
G MIR412 microRNA 412 JBrowse link 14 101,065,447 101,065,537 RGD:6480464
G MIR423 microRNA 423 JBrowse link 17 30,117,079 30,117,172 RGD:6480464
G MIR433 microRNA 433 JBrowse link 14 100,881,886 100,881,978 RGD:6480464
G MIR450A1 microRNA 450a-1 JBrowse link X 134,540,341 134,540,431 RGD:6480464
G MIR487B microRNA 487b JBrowse link 14 101,046,455 101,046,538 RGD:6480464
G MIR488 microRNA 488 JBrowse link 1 177,029,363 177,029,445 RGD:6480464
G MIR497 microRNA 497 JBrowse link 17 7,017,911 7,018,022 RGD:6480464
G MIR503 microRNA 503 JBrowse link X 134,546,328 134,546,398 RGD:6480464
G MIR541 microRNA 541 JBrowse link 14 101,064,495 101,064,578 RGD:6480464
G MIR542 microRNA 542 JBrowse link X 134,541,341 134,541,437 RGD:6480464
G MIR551B microRNA 551b JBrowse link 3 168,551,854 168,551,949 RGD:6480464
G MIR582 microRNA 582 JBrowse link 5 59,703,606 59,703,703 RGD:6480464
G MIR652 microRNA 652 JBrowse link X 110,055,329 110,055,426 RGD:6480464
G MIR653 microRNA 653 JBrowse link 7 93,482,760 93,482,855 RGD:6480464
G MIR665 microRNA 665 JBrowse link 14 100,875,033 100,875,104 RGD:6480464
G MIR675 microRNA 675 JBrowse link 11 1,996,759 1,996,831 RGD:6480464
G MIR7-2 microRNA 7-2 JBrowse link 15 88,611,825 88,611,934 RGD:6480464
G MIR760 microRNA 760 JBrowse link 1 93,846,832 93,846,911 RGD:6480464
G MIR770 microRNA 770 JBrowse link 14 100,852,390 100,852,487 RGD:6480464
G MIR873 microRNA 873 JBrowse link 9 28,888,879 28,888,955 RGD:6480464
G MIR877 microRNA 877 JBrowse link 6 30,584,332 30,584,417 RGD:6480464
G MIRLET7B microRNA let-7b JBrowse link 22 46,113,686 46,113,768 RGD:6480464
G MIRLET7I microRNA let-7i JBrowse link 12 62,603,686 62,603,769 RGD:6480464
G MTM1 myotubularin 1 JBrowse link X 150,562,658 150,673,143 RGD:6480464
G NAPA NSF attachment protein alpha JBrowse link 19 47,487,637 47,515,091 RGD:6480464
G NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 JBrowse link 2 239,892,442 240,025,402 RGD:6480464
G NEFH neurofilament heavy JBrowse link 22 29,480,218 29,491,390 RGD:6480464
G NEFL neurofilament light JBrowse link 8 24,950,955 24,956,612 RGD:6480464
G NEFM neurofilament medium JBrowse link 8 24,913,761 24,919,093 RGD:6480464
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 17 46,590,669 46,757,464 RGD:6480464
G NUPR2 nuclear protein 2, transcriptional regulator JBrowse link 7 56,114,681 56,116,417 RGD:6480464
G PDIA3 protein disulfide isomerase family A member 3 JBrowse link 15 43,746,438 43,773,278 RGD:6480464
G PDLIM3 PDZ and LIM domain 3 JBrowse link 4 185,500,660 185,535,558 RGD:6480464
G PGAM1 phosphoglycerate mutase 1 JBrowse link 10 97,426,191 97,433,444 RGD:6480464
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 JBrowse link 17 49,223,366 49,230,787 RGD:6480464
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 6 37,170,152 37,175,428 RGD:6480464
G PKM pyruvate kinase M1/2 JBrowse link 15 72,199,029 72,231,624 RGD:6480464
G POU2F1 POU class 2 homeobox 1 JBrowse link 1 167,220,878 167,427,345 RGD:6480464
G PRKCSH protein kinase C substrate 80K-H JBrowse link 19 11,435,257 11,450,968 RGD:6480464
G PTGDS prostaglandin D2 synthase JBrowse link 9 136,977,504 136,981,742 RGD:6480464
G PYGB glycogen phosphorylase B JBrowse link 20 25,248,039 25,298,012 RGD:6480464
G PYGM glycogen phosphorylase, muscle associated JBrowse link 11 64,746,389 64,760,715 RGD:6480464
G RALGAPA2 Ral GTPase activating protein catalytic subunit alpha 2 JBrowse link 20 20,389,530 20,712,644 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RTKN2 rhotekin 2 JBrowse link 10 62,159,131 62,268,879 RGD:6480464
G S100Z S100 calcium binding protein Z JBrowse link 5 76,849,953 76,952,882 RGD:6480464
G SCLT1 sodium channel and clathrin linker 1 JBrowse link 4 128,874,390 129,093,580 RGD:6480464
G SEPTIN8 septin 8 JBrowse link 5 132,750,819 132,778,216 RGD:6480464
G SH2D4A SH2 domain containing 4A JBrowse link 8 19,313,570 19,396,218 RGD:6480464
G SHANK3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 22 50,672,823 50,733,212 RGD:6480464
G SIL1 SIL1 nucleotide exchange factor JBrowse link 5 138,946,724 139,198,368 RGD:6480464
G SLC10A7 solute carrier family 10 member 7 JBrowse link 4 146,253,981 146,522,351 RGD:6480464
G SLTM SAFB like transcription modulator JBrowse link 15 58,879,050 58,934,313 RGD:6480464
G SOD3 superoxide dismutase 3 JBrowse link 4 24,795,478 24,800,845 RGD:6480464
G SPPL3 signal peptide peptidase like 3 JBrowse link 12 120,762,510 120,904,358 RGD:6480464
G SPTAN1 spectrin alpha, non-erythrocytic 1 JBrowse link 9 128,552,564 128,633,662 RGD:6480464
G STMN1 stathmin 1 JBrowse link 1 25,884,179 25,906,877 RGD:6480464
G STRBP spermatid perinuclear RNA binding protein JBrowse link 9 123,109,494 123,268,586 RGD:6480464
G STYXL1 serine/threonine/tyrosine interacting like 1 JBrowse link 7 75,995,820 76,049,344 RGD:6480464
G TAX1BP1 Tax1 binding protein 1 JBrowse link 7 27,739,373 27,829,767 RGD:6480464
G TBC1D5 TBC1 domain family member 5 JBrowse link 3 17,157,162 17,742,739 RGD:6480464
G TMEM192 transmembrane protein 192 JBrowse link 4 165,070,608 165,112,913 RGD:6480464
G TPI1 triosephosphate isomerase 1 JBrowse link 12 6,866,834 6,870,948 RGD:6480464
G UBA1 ubiquitin like modifier activating enzyme 1 JBrowse link X 47,190,847 47,215,128 RGD:6480464
G UBN2 ubinuclein 2 JBrowse link 7 139,228,408 139,329,421 RGD:6480464
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 JBrowse link 16 21,953,361 21,983,660 RGD:6480464
G VIM vimentin JBrowse link 10 17,228,241 17,237,593 RGD:6480464
G XIAP X-linked inhibitor of apoptosis JBrowse link X 123,859,708 123,913,972 RGD:6480464
G ZNF169 zinc finger protein 169 JBrowse link 9 94,259,266 94,303,967 RGD:6480464
G ZNF407 zinc finger protein 407 JBrowse link 18 74,590,475 75,065,672 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24141
    role 24034
      biological role 24000
        aetiopathogenetic role 22561
          neurotoxin 19057
            2,5-hexanedione 170
Path 2
Term Annotations click to browse term
  CHEBI ontology 24141
    subatomic particle 24095
      composite particle 24095
        hadron 24095
          baryon 24095
            nucleon 24095
              atomic nucleus 24095
                atom 24095
                  main group element atom 23924
                    p-block element atom 23924
                      carbon group element atom 23656
                        carbon atom 23612
                          organic molecular entity 23612
                            organic group 22086
                              organic divalent group 22060
                                organodiyl group 22060
                                  carbonyl group 22035
                                    carbonyl compound 22035
                                      ketone 18148
                                        diketone 1155
                                          2,5-hexanedione 170
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.