Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor
go back to main search page
Accession:CHEBI:84803 term browser browse the term
Definition:Any EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with a phosphate group as acceptor (EC 2.7.4.*).
Synonyms:related_synonym: EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitors;   EC 2.7.4.* inhibitor;   EC 2.7.4.* inhibitors



show annotations for term's descendants           Sort by:
 
corilagin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in increased expression of AKT1 protein] CTD PMID:34605098 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in increased expression of BAX protein] CTD PMID:34605098 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein] CTD PMID:34605098 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP3 caspase 3 multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein] CTD PMID:34605098 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CAT catalase multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30582900 PMID:34605098 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in increased activity of HMGCR protein] CTD PMID:34605098 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G IL6 interleukin 6 multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in increased expression of IL6 protein] CTD PMID:34605098 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions ISO corilagin inhibits the reaction [1-naphthyl isothiocyanate decreases expression of nr1h4 mRNA and protein in rat liver]; corilagin increases expression of nr1h4 mRNA and protein in rat embryonic liver cells RGD PMID:29235094 RGD:15042872 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO corilagin inhibits the reaction [Doxorubicin results in increased expression of PPARG protein] CTD PMID:34605098 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G TNF tumor necrosis factor decreases secretion
multiple interactions
ISO corilagin results in decreased secretion of TNF protein
corilagin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]
CTD PMID:12628509 PMID:34605098 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
ellagic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 increases expression EXP Ellagic Acid results in increased expression of ACP3 mRNA CTD PMID:12002526 NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,298
JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] CTD PMID:32971123 NCBI chr19:11,574,660...11,578,975
Ensembl chr19:11,574,653...11,579,993
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 increases expression EXP Ellagic Acid results in increased expression of AIFM1 protein CTD PMID:23554011 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation EXP Ellagic Acid results in increased phosphorylation of AKT1 protein CTD PMID:26986492 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALB albumin multiple interactions
affects binding
EXP ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]
Ellagic Acid binds to ALB protein
CTD PMID:6343536 PMID:25247703 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase decreases activity EXP Ellagic Acid results in decreased activity of ALKBH2 protein CTD PMID:31088072 NCBI chr12:109,088,189...109,093,472
Ensembl chr12:109,088,188...109,093,631
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 decreases expression
increases expression
EXP Ellagic Acid results in decreased expression of APAF1 mRNA
Ellagic Acid results in increased expression of APAF1 mRNA
CTD PMID:12002526 PMID:35179410 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 increases expression EXP Ellagic Acid results in increased expression of ASCL1 mRNA CTD PMID:12002526 NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) increases expression EXP Ellagic Acid results in increased expression of ASNS mRNA CTD PMID:12002526 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
JBrowse link
G ATF3 activating transcription factor 3 increases expression EXP Ellagic Acid results in increased expression of ATF3 mRNA CTD PMID:12002526 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATG5 autophagy related 5 increases expression EXP Ellagic Acid results in increased expression of ATG5 mRNA CTD PMID:12002526 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G BAD BCL2 associated agonist of cell death increases expression EXP Ellagic Acid results in increased expression of BAD protein CTD PMID:23554011 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of BAX mRNA]
Ellagic Acid results in increased expression of BAX mRNA
CTD PMID:29854611 PMID:35179410 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions
decreases expression
EXP
ISO
Ellagic Acid results in increased expression of BCL2 protein
[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of BCL2 mRNA]
Ellagic Acid results in decreased expression of BCL2 mRNA
CTD PMID:20103723 PMID:22386815 PMID:29854611 PMID:35179410 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BMP6 bone morphogenetic protein 6 decreases expression EXP Ellagic Acid results in decreased expression of BMP6 mRNA CTD PMID:12002526 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BRF1 BRF1 RNA polymerase III transcription initiation factor subunit decreases expression EXP Ellagic Acid results in decreased expression of BRF1 mRNA CTD PMID:12002526 NCBI chr14:105,209,286...105,315,589
Ensembl chr14:105,209,286...105,315,589
JBrowse link
G CALR calreticulin decreases expression EXP Ellagic Acid results in decreased expression of CALR mRNA CTD PMID:12002526 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CASP3 caspase 3 increases expression
decreases expression
decreases activity
increases activity
multiple interactions
EXP
ISO
Ellagic Acid results in increased expression of CASP3 mRNA
Ellagic Acid results in decreased expression of CASP3 mRNA
Ellagic Acid results in decreased activity of CASP3 protein
Ellagic Acid results in increased activity of CASP3 protein
Ellagic Acid results in increased expression of and results in increased activity of CASP3 protein
Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased activity of CASP3 protein]
CTD PMID:12002526 PMID:22386815 PMID:23554011 PMID:23811531 PMID:28815802 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP9 caspase 9 multiple interactions EXP Ellagic Acid results in increased expression of and results in increased activity of CASP9 protein CTD PMID:23554011 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase increases activity
multiple interactions
ISO Ellagic Acid results in increased activity of CAT protein
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:20074268 PMID:24877639 PMID:29864931 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases secretion EXP Ellagic Acid results in decreased secretion of CCL2 protein CTD PMID:20816778 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCNG1 cyclin G1 decreases expression ISO ellagic acid inhibits the reaction [estrogen increases expression of Ccng1 mRNA and protein in rat mammary tissue] RGD PMID:23791885 RGD:151356928 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151
JBrowse link
G CD14 CD14 molecule decreases expression EXP Ellagic Acid results in decreased expression of CD14 mRNA CTD PMID:20816778 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression EXP Ellagic Acid results in decreased expression of CDK1 protein CTD PMID:23554011 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
[resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
Ellagic Acid results in increased expression of CDKN1A protein
[Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA; Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]]
CTD PMID:15735102 PMID:20103723 PMID:23554011 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CTSD cathepsin D multiple interactions ISO Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CTSK cathepsin K multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein] CTD PMID:32971123 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
decreases expression
EXP Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
Ellagic Acid results in decreased expression of CXCL8 mRNA
CTD PMID:18377686 PMID:35179410 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression
decreases activity
EXP
ISO
Ellagic Acid results in decreased expression of CYP1A1 mRNA
Ellagic Acid results in decreased activity of CYP1A1 protein
CTD PMID:19329757 PMID:20816778 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity
multiple interactions
ISO Ellagic Acid results in decreased activity of CYP1B1 protein
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]
CTD PMID:19329757 PMID:20103723 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G DAXX death domain associated protein decreases expression EXP Ellagic Acid results in decreased expression of DAXX mRNA CTD PMID:12002526 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016
JBrowse link
G DFFA DNA fragmentation factor subunit alpha decreases expression EXP Ellagic Acid results in decreased expression of DFFA mRNA CTD PMID:12002526 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529
JBrowse link
G E4F1 E4F transcription factor 1 increases expression EXP Ellagic Acid results in increased expression of E4F1 mRNA CTD PMID:12002526 NCBI chr16:2,223,591...2,235,742
Ensembl chr16:2,223,580...2,235,742
JBrowse link
G EGR3 early growth response 3 decreases expression EXP Ellagic Acid results in decreased expression of EGR3 mRNA CTD PMID:12002526 NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
JBrowse link
G ENDOG endonuclease G increases expression EXP Ellagic Acid results in increased expression of ENDOG protein CTD PMID:23554011 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676
JBrowse link
G EP300 E1A binding protein p300 increases expression EXP Ellagic Acid results in increased expression of EP300 mRNA CTD PMID:12002526 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 increases expression EXP Ellagic Acid results in increased expression of EPS15 mRNA CTD PMID:12002526 NCBI chr 1:51,354,263...51,519,266
Ensembl chr 1:51,354,263...51,519,266
JBrowse link
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression EXP Ellagic Acid results in increased expression of EZH1 mRNA CTD PMID:12002526 NCBI chr17:42,700,275...42,745,040
Ensembl chr17:42,700,275...42,745,049
JBrowse link
G F12 coagulation factor XII multiple interactions
increases activity
EXP ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] CTD PMID:6343536 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 decreases expression EXP Ellagic Acid results in decreased expression of FGFR1 mRNA CTD PMID:12002526 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FLNA filamin A decreases expression EXP Ellagic Acid results in decreased expression of FLNA mRNA CTD PMID:12002526 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
G FN1 fibronectin 1 multiple interactions ISO Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:24877639 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein] CTD PMID:20103723 PMID:32971123 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases activity EXP Ellagic Acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GAL galanin and GMAP prepropeptide multiple interactions ISO Ellagic Acid inhibits the reaction [phosalone results in increased activity of GAL protein] CTD PMID:27965107 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression EXP Ellagic Acid results in decreased expression of GPLD1 mRNA CTD PMID:12002526 NCBI chr 6:24,423,969...24,495,287
Ensembl chr 6:24,424,565...24,495,205
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of GPT protein] CTD PMID:24877639 PMID:29935397 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA] CTD PMID:29935397 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein] CTD PMID:24877639 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTA4 glutathione S-transferase alpha 4 increases expression EXP Ellagic Acid results in increased expression of GSTA4 mRNA CTD PMID:12002526 NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304
JBrowse link
G GSTT1 glutathione S-transferase theta 1 affects expression ISO Ellagic Acid affects the expression of GSTT1 protein CTD PMID:9855024
G GTF2E2 general transcription factor IIE subunit 2 increases expression EXP Ellagic Acid results in increased expression of GTF2E2 mRNA CTD PMID:12002526 NCBI chr 8:30,578,318...30,658,236
Ensembl chr 8:30,578,318...30,658,236
JBrowse link
G GTF2H4 general transcription factor IIH subunit 4 increases expression EXP Ellagic Acid results in increased expression of GTF2H4 mRNA CTD PMID:12002526 NCBI chr 6:30,908,207...30,914,106
Ensembl chr 6:30,908,207...30,914,106
JBrowse link
G GUSB glucuronidase beta multiple interactions ISO Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:21762681 NCBI chr 7:65,960,684...65,982,213
Ensembl chr 7:65,960,684...65,982,215
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha decreases expression EXP Ellagic Acid results in decreased expression of HIF1A mRNA CTD PMID:12002526 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HLCS holocarboxylase synthetase decreases activity EXP Ellagic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr21:36,748,625...36,990,211
Ensembl chr21:36,748,626...36,990,236
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions
EXP Ellagic Acid results in increased expression of HMOX1 mRNA; Ellagic Acid results in increased expression of HMOX1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein
CTD PMID:22386815 PMID:23546295 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HRAS HRas proto-oncogene, GTPase multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] CTD PMID:20103723 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IER2 immediate early response 2 increases expression EXP Ellagic Acid results in increased expression of IER2 mRNA CTD PMID:12002526 NCBI chr19:13,150,411...13,154,911
Ensembl chr19:13,150,411...13,154,911
JBrowse link
G IFNG interferon gamma multiple interactions ISO Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG protein] CTD PMID:29854611 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 increases expression EXP Ellagic Acid results in increased expression of IGFBP2 mRNA CTD PMID:12002526 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 decreases expression EXP Ellagic Acid results in decreased expression of IGFBP4 mRNA CTD PMID:12002526 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725
JBrowse link
G IL1B interleukin 1 beta decreases expression
multiple interactions
EXP
ISO
Ellagic Acid results in decreased expression of IL1B mRNA
Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
CTD PMID:18377686 PMID:20816778 PMID:21762681 PMID:24877639 PMID:27965107 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1R1 interleukin 1 receptor type 1 decreases expression EXP Ellagic Acid results in decreased expression of IL1R1 mRNA CTD PMID:20816778 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G IL6 interleukin 6 multiple interactions ISO Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL6 protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D increases expression EXP Ellagic Acid results in increased expression of INPP5D mRNA CTD PMID:12002526 NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903
JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 increases expression EXP Ellagic Acid results in increased expression of IQGAP2 mRNA CTD PMID:12002526 NCBI chr 5:76,403,285...76,708,132
Ensembl chr 5:76,403,285...76,708,132
JBrowse link
G IRF9 interferon regulatory factor 9 increases expression EXP Ellagic Acid results in increased expression of IRF9 mRNA CTD PMID:12002526 NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Ellagic Acid results in decreased expression of JUN mRNA; Ellagic Acid results in decreased expression of JUN protein modified form CTD PMID:23811531 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KLK3 kallikrein related peptidase 3 decreases expression EXP Ellagic Acid results in decreased expression of KLK3 mRNA CTD PMID:12002526 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764
JBrowse link
G LITAF lipopolysaccharide induced TNF factor increases expression EXP Ellagic Acid results in increased expression of LITAF mRNA CTD PMID:12002526 NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381
JBrowse link
G MAP1A microtubule associated protein 1A decreases expression EXP Ellagic Acid results in decreased expression of MAP1A mRNA CTD PMID:12002526 NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 decreases expression EXP Ellagic Acid results in decreased expression of MAP3K1 mRNA; Ellagic Acid results in decreased expression of MAP3K1 protein CTD PMID:23811531 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein] CTD PMID:32971123 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK11 mitogen-activated protein kinase 11 increases expression EXP Ellagic Acid results in increased expression of MAPK11 mRNA CTD PMID:23811531 NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions ISO Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein] CTD PMID:27965107 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:32971123 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK9 protein CTD PMID:15735102 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 decreases activity ISO Ellagic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MMD monocyte to macrophage differentiation associated increases expression EXP Ellagic Acid results in increased expression of MMD mRNA CTD PMID:12002526 NCBI chr17:55,392,622...55,421,835
Ensembl chr17:55,392,622...55,421,924
JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
decreases activity
decreases expression
EXP Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein; zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein]
Ellagic Acid results in decreased activity of MMP2 protein
Ellagic Acid results in decreased expression of MMP2 mRNA
CTD PMID:21573219 PMID:35179410 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression
decreases activity
EXP Ellagic Acid results in decreased expression of MMP9 mRNA
Ellagic Acid results in decreased activity of MMP9 protein
CTD PMID:35179410 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein] CTD PMID:32971123 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization
affects response to substance
increases expression
multiple interactions
EXP
ISO
Ellagic Acid affects the localization of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Ellagic Acid
Ellagic Acid results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of NFE2L2 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of and affects the localization of NFE2L2 protein; [Paraquat co-treated with Ellagic Acid] results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of and affects the localization of NFE2L2 protein
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
CTD PMID:22386815 PMID:23546295 PMID:30503583 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 decreases expression EXP Ellagic Acid results in decreased expression of NFKB2 mRNA CTD PMID:12002526 PMID:35179410 NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524
JBrowse link
G NNAT neuronatin increases expression EXP Ellagic Acid results in increased expression of NNAT mRNA CTD PMID:12002526 NCBI chr20:37,521,250...37,523,690
Ensembl chr20:37,521,206...37,523,690
JBrowse link
G NOP56 NOP56 ribonucleoprotein decreases expression EXP Ellagic Acid results in decreased expression of NOP56 mRNA CTD PMID:12002526 NCBI chr20:2,652,632...2,658,393
Ensembl chr20:2,652,593...2,658,393
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO
EXP
Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]
Ellagic Acid results in decreased expression of NOS2 mRNA
CTD PMID:28815802 PMID:35179410 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NPAS2 neuronal PAS domain protein 2 increases expression EXP Ellagic Acid results in increased expression of NPAS2 mRNA CTD PMID:12002526 NCBI chr 2:100,818,723...100,996,829
Ensembl chr 2:100,820,139...100,996,829
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP Ellagic Acid results in increased expression of NQO1 mRNA; Ellagic Acid results in increased expression of NQO1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 protein
CTD PMID:23546295 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases activity EXP
ISO
Ellagic Acid results in increased activity of NR1I3 protein CTD PMID:21821919 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G PARG poly(ADP-ribose) glycohydrolase decreases activity EXP Ellagic Acid results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:25247703 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] CTD PMID:20103723 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 multiple interactions ISO Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased activity of PDIA2 protein] CTD PMID:25247703 NCBI chr16:283,164...287,215
Ensembl chr16:283,164...287,215
JBrowse link
G PGD phosphogluconate dehydrogenase decreases activity EXP Ellagic Acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
JBrowse link
G PLA2G2A phospholipase A2 group IIA decreases expression EXP Ellagic Acid results in decreased expression of PLA2G2A mRNA CTD PMID:20816778 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
JBrowse link
G PLP2 proteolipid protein 2 increases expression EXP Ellagic Acid results in increased expression of PLP2 mRNA CTD PMID:12002526 NCBI chr  X:49,171,898...49,175,235
Ensembl chr  X:49,171,898...49,175,235
JBrowse link
G PML PML nuclear body scaffold decreases expression EXP Ellagic Acid results in decreased expression of PML mRNA CTD PMID:12002526 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G PPARD peroxisome proliferator activated receptor delta decreases expression EXP Ellagic Acid results in decreased expression of PPARD mRNA CTD PMID:12002526 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression EXP Ellagic Acid results in increased expression of PPARG protein CTD PMID:23811531 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha decreases expression
multiple interactions
ISO Ellagic Acid results in decreased expression of PPARGC1A mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]
CTD PMID:30503583 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 decreases expression EXP Ellagic Acid results in decreased expression of PRKG1 mRNA CTD PMID:12002526 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423
JBrowse link
G PTN pleiotrophin decreases expression
increases expression
EXP Ellagic Acid results in decreased expression of PTN mRNA
Ellagic Acid results in increased expression of PTN mRNA
CTD PMID:12002526 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
JBrowse link
G PTPRN2 protein tyrosine phosphatase receptor type N2 increases expression EXP Ellagic Acid results in increased expression of PTPRN2 mRNA CTD PMID:12002526 NCBI chr 7:157,539,056...158,587,823
Ensembl chr 7:157,539,056...158,587,823
JBrowse link
G RAN RAN, member RAS oncogene family decreases expression EXP Ellagic Acid results in decreased expression of RAN mRNA CTD PMID:12002526 NCBI chr12:130,872,066...130,877,678
Ensembl chr12:130,872,037...130,877,678
JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions ISO Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs increases expression
multiple interactions
EXP Ellagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK protein
zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein]
CTD PMID:21573219 NCBI chr 9:36,036,913...36,124,455
Ensembl chr 9:36,036,913...36,124,455
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions
EXP
ISO
Ellagic Acid results in decreased expression of RELA mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RELA protein]
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
CTD PMID:12002526 PMID:24877639 PMID:27965107 PMID:32971123 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RGS5 regulator of G protein signaling 5 decreases expression EXP Ellagic Acid results in decreased expression of RGS5 mRNA CTD PMID:12002526 NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791
Ensembl chr 1:163,111,121...163,321,791
JBrowse link
G SCD stearoyl-CoA desaturase decreases expression EXP Ellagic Acid results in decreased expression of SCD mRNA CTD PMID:20816778 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G SEPTIN2 septin 2 increases expression EXP Ellagic Acid results in increased expression of SEPTIN2 mRNA CTD PMID:12002526 NCBI chr 2:241,315,355...241,354,027
Ensembl chr 2:241,315,100...241,354,027
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA] CTD PMID:29935397 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 decreases expression EXP Ellagic Acid results in decreased expression of SOD3 mRNA CTD PMID:12002526 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein] CTD PMID:32971123 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions
increases expression
ISO Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA]
Ellagic Acid results in increased expression of STAR mRNA
CTD PMID:30503583 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression
decreases expression
EXP Ellagic Acid results in increased expression of STAT3 mRNA
Ellagic Acid results in decreased expression of STAT3 mRNA
CTD PMID:12002526 PMID:20816778 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G TAF1C TATA-box binding protein associated factor, RNA polymerase I subunit C decreases expression EXP Ellagic Acid results in decreased expression of TAF1C mRNA CTD PMID:12002526 NCBI chr16:84,177,855...84,187,057
Ensembl chr16:84,177,847...84,187,070
JBrowse link
G TCF12 transcription factor 12 increases expression EXP Ellagic Acid results in increased expression of TCF12 mRNA CTD PMID:12002526 NCBI chr15:56,918,090...57,291,310
Ensembl chr15:56,918,623...57,299,281
JBrowse link
G TERT telomerase reverse transcriptase multiple interactions
increases expression
EXP
ISO
Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
Ellagic Acid results in increased expression of TERT mRNA alternative form
Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein]
CTD PMID:19501078 PMID:27965107 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TFAM transcription factor A, mitochondrial decreases expression EXP Ellagic Acid results in decreased expression of TFAM mRNA CTD PMID:12002526 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression
multiple interactions
EXP
ISO
Ellagic Acid results in increased expression of TGFB1 mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]
CTD PMID:12002526 PMID:24877639 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]
Ellagic Acid results in decreased expression of TNF mRNA
CTD PMID:21762681 PMID:24877639 PMID:27965107 PMID:28815802 PMID:29455002 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a multiple interactions
affects binding
ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]
Ellagic Acid binds to TNFRSF11A protein
CTD PMID:32971123 NCBI chr18:62,325,310...62,391,288
Ensembl chr18:62,325,287...62,391,288
JBrowse link
G TNFSF11 TNF superfamily member 11 affects binding
multiple interactions
ISO Ellagic Acid binds to TNFSF11 protein
Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
CTD PMID:32971123 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TNNT2 troponin T2, cardiac type multiple interactions ISO Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:21762681 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TP53 tumor protein p53 increases expression
multiple interactions
EXP
ISO
Ellagic Acid results in increased expression of TP53 mRNA; Ellagic Acid results in increased expression of TP53 protein
Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]
Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]
CTD PMID:15735102 PMID:23554011 PMID:27965107 PMID:35179410 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G UGP2 UDP-glucose pyrophosphorylase 2 decreases expression EXP Ellagic Acid results in decreased expression of UGP2 mRNA CTD PMID:12002526 NCBI chr 2:63,840,969...63,891,560
Ensembl chr 2:63,840,952...63,891,562
JBrowse link
G USP4 ubiquitin specific peptidase 4 decreases expression EXP Ellagic Acid results in decreased expression of USP4 mRNA CTD PMID:12002526 NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712
JBrowse link
G WARS1 tryptophanyl-tRNA synthetase 1 increases expression EXP Ellagic Acid results in increased expression of WARS1 mRNA CTD PMID:12002526 NCBI chr14:100,333,790...100,376,327
Ensembl chr14:100,333,790...100,376,805
JBrowse link
G WEE1 WEE1 G2 checkpoint kinase decreases expression EXP Ellagic Acid results in decreased expression of WEE1 protein CTD PMID:23554011 NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457
JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 decreases expression EXP Ellagic Acid results in decreased expression of ZBTB16 mRNA CTD PMID:12002526 NCBI chr11:114,059,711...114,256,770
Ensembl chr11:114,059,041...114,256,765
JBrowse link
G ZMYM2 zinc finger MYM-type containing 2 increases expression EXP Ellagic Acid results in increased expression of ZMYM2 mRNA CTD PMID:12002526 NCBI chr13:19,863,840...20,089,115
Ensembl chr13:19,958,677...20,091,829
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25538
    role 25475
      biological role 25450
        biochemical role 24704
          enzyme inhibitor 21589
            EC 2.* (transferase) inhibitor 15182
              EC 2.7.* (P-containing group transferase) inhibitor 14760
                EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor 136
                  EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor + 136
paths to the root