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ONTOLOGY REPORT - ANNOTATIONS


Term:N(6)-butyryl-cAMP
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Accession:CHEBI:84605 term browser browse the term
Definition:A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP in which the exocyclic amino group on the purine fragment is carrying a butyryl substituent.
Synonyms:exact_synonym: N-{9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda(5)-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-9H-purin-6-yl}butanamide
 related_synonym: 6-MB-cAMP;   Cyclic N6-monobutyryl-AMP;   Formula=C14H18N5O7P;   InChI=1S/C14H18N5O7P/c1-2-3-8(20)18-12-9-13(16-5-15-12)19(6-17-9)14-10(21)11-7(25-14)4-24-27(22,23)26-11/h5-7,10-11,14,21H,2-4H2,1H3,(H,22,23)(H,15,16,18,20)/t7-,10-,11-,14-/m1/s1;   InChIKey=NVGDLMUKSMHEQT-FRJWGUMJSA-N;   Monobutyryl adnosine cyclic 3',5'-monophosphate;   Monobutyryl cyclic AMP;   N(6)-Butyryl adenosine-3',5'-cyclic monophosphate;   N(6)-Butyryl cyclic AMP;   N(6)-Monobutyryl adenosine-3',5'-cyclic monophosphate;   N(6)-Monobutyryl cyclic AMP;   N(6)-butanoyl-cAMP;   N6-Butyryl-3',5'-cyclic AMP;   N6-Butyryladenosine 3',5'-cyclic phosphate;   N6-Monobutyryl-cAMP;   N6-Monobutyryladenosine-3',5'-cyclic monophosphate;   N6-Monobutyryladenosine-3',5'-cyclic monophosphoric acid;   SMILES=CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O
 xref: CAS:13117-60-7 "ChemIDplus"
 xref_mesh: MESH:C002373
 xref: PMID:22240166 "Europe PMC";   PMID:24605759 "SUBMITTER";   PMID:24666699 "Europe PMC";   PMID:24740327 "Europe PMC";   PMID:6290794 "Europe PMC";   Reaxys:1054786 "Reaxys"


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N(6)-butyryl-cAMP term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Crem cAMP responsive element modulator JBrowse link 17 57,021,704 57,090,888 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 3 43,111,258 43,128,391 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 6 51,265,509 51,356,383 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      biological role 19700
        pharmacological role 18807
          agonist 18191
            protein kinase agonist 8513
              N(6)-butyryl-cAMP 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      chalcogen 19340
                        oxygen atom 19301
                          oxygen molecular entity 19301
                            hydroxides 19053
                              oxoacid 18115
                                pnictogen oxoacid 9854
                                  phosphorus oxoacid 8676
                                    phosphoric acids 7345
                                      phosphoric acid 7345
                                        phosphoric acid derivative 6996
                                          phosphate 6996
                                            organic phosphate 6995
                                              carbohydrate phosphate 1519
                                                phospho sugar 1449
                                                  aldose phosphate 1447
                                                    aldopentose phosphate 1441
                                                      ribose phosphate 1435
                                                        ribonucleotide 1394
                                                          purine ribonucleotide 1367
                                                            adenyl ribonucleotide 1242
                                                              3',5'-cyclic AMP 1077
                                                                N(6)-butyryl-cAMP 14
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