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Accession:CHEBI:8452 term browser browse the term
Definition:An aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds.
Synonyms:related_synonym: 2,8-Diaminoacridine;   3,6-acridinediamine;   Formula=C13H11N3;   InChI=1S/C13H11N3/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10/h1-7H,14-15H2;   InChIKey=WDVSHHCDHLJJJR-UHFFFAOYSA-N;   Proflavin;   SMILES=Nc1ccc2cc3ccc(N)cc3nc2c1;   acridine-3,6-diamine;   proflavina;   proflavine;   proflavinum
 alt_id: CHEBI:44910;   CHEBI:45272
 xref: Beilstein:166050;   CAS:92-62-6;   DrugBank:DB01123;   Drug_Central:2277;   KEGG:C11181
 xref_mesh: MESH:D011370
 xref: PDBeChem:PRL;   PMID:11960666;   PMID:20178341;   PMID:21435875;   PMID:2242050;   PMID:22555876;   PMID:22978751;   PMID:6987510;   PMID:7009393;   PMID:8579793;   Reaxys:166050;   Wikipedia:Proflavine
 cyclic_relationship: is_conjugate_base_of CHEBI:74711

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3,6-diaminoacridine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esrra estrogen related receptor, alpha JBrowse link 1 222,168,729 222,178,842 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      chemical role 19258
        photochemical role 225
          chromophore 53
            3,6-diaminoacridine 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic molecule 19472
                              organic cyclic compound 19236
                                organic heterocyclic compound 18361
                                  organic heteropolycyclic compound 17707
                                    organic heterotricyclic compound 14592
                                      dibenzopyridine 155
                                        acridines 122
                                          aminoacridines 17
                                            3,6-diaminoacridine 10
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.