Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-dimethylacetamide
go back to main search page
Accession:CHEBI:84254 term browser browse the term
Definition:A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.
Synonyms:related_synonym: Formula=C4H9NO;   InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3;   InChIKey=FXHOOIRPVKKKFG-UHFFFAOYSA-N;   SMILES=CN(C)C(C)=O;   dimethylacetamide
 xref: CAS:127-19-5;   KEGG:C20339
 xref_mesh: MESH:C013959
 xref: PMID:25518943;   Reaxys:1737614;   Wikipedia:Dimethylacetamide


show annotations for term's descendants           Sort by:
N,N-dimethylacetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase affects response to substance ISO CAT gene SNP affects the susceptibility to dimethylacetamide CTD PMID:28749186 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] CTD PMID:27782292 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:27782292 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein]		 CTD PMID:27782292 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:27782292 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:27782292 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      atom 19885
        nonmetal atom 19809
          nitrogen atom 18982
            nitrogen molecular entity 18982
              organonitrogen compound 18834
                carboxamide 17545
                  acetamides 14634
                    N,N-dimethylacetamide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            heteroorganic entity 19521
                              organochalcogen compound 19282
                                organooxygen compound 19197
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      carboacyl group 17700
                                        univalent carboacyl group 17700
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              acetamides 14634
                                                acetamide 8758
                                                  N,N-dimethylacetamide 6
paths to the root