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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-dimethylacetamide
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Accession:CHEBI:84254 term browser browse the term
Definition:A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.
Synonyms:related_synonym: dimethylacetamide
 xref: CAS:127-19-5
 xref_mesh: MESH:C013959
 xref: Reaxys:1737614;   kegg.compound:C20339;   pubmed:25518943;   wikipedia.en:Dimethylacetamide
 chemrof_formula: C4H9NO
 chemrof_smiles: CC(=O)N(C)C
 chemrof_inchikey: FXHOOIRPVKKKFG-UHFFFAOYSA-N
 chemrof_inchi: InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
 cyclic_relationship: has_functional_parent CHEBI:27856


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N,N-dimethylacetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase affects response to substance ISO CAT gene SNP affects the susceptibility to dimethylacetamide CTD PMID:28749186 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] CTD PMID:27782292 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:27782292 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein] 		CTD PMID:27782292 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:27782292 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:27782292 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      atom 20872
        nonmetal atom 20781
          nitrogen atom 19576
            nitrogen molecular entity 19576
              organonitrogen compound 19311
                carboxamide 17697
                  acetamides 13993
                    N,N-dimethylacetamide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            heteroorganic entity 20201
                              organochalcogen compound 19822
                                organooxygen compound 19713
                                  carboxamide 17697
                                    acetamides 13993
                                      N,N-dimethylacetamide 6
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