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ONTOLOGY REPORT - ANNOTATIONS


Term:L-valine derivative
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Accession:CHEBI:84129 term browser browse the term
Definition:A proteinogenic amino acid derivative resulting from reaction of L-valine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-valine by a heteroatom.
Synonyms:related_synonym: L-valine derivatives


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ritonavir term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 JBrowse link 2 69,238,282 69,342,616 RGD:6480464
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 JBrowse link 5 8,893,614 8,959,226 RGD:6480464
G Acss2 acyl-CoA synthetase short-chain family member 2 JBrowse link 2 155,518,043 155,562,743 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:6480464
G Alb albumin JBrowse link 5 90,460,870 90,476,602 RGD:6480464
G Bak1 BCL2-antagonist/killer 1 JBrowse link 17 27,019,812 27,028,627 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 11 117,849,237 117,855,743 RGD:6480464
G Casp1 caspase 1 JBrowse link 9 5,298,517 5,307,281 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Ccl20 chemokine (C-C motif) ligand 20 JBrowse link 1 83,116,766 83,119,167 RGD:6480464
G Ccl3 chemokine (C-C motif) ligand 3 JBrowse link 11 83,647,843 83,649,378 RGD:6480464
G Ccl4 chemokine (C-C motif) ligand 4 JBrowse link 11 83,648,624 83,664,683 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 3 36,564,865 36,573,038 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 13 100,778,739 100,786,486 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:6480464
G Ccnd2 cyclin D2 JBrowse link 6 127,125,162 127,152,188 RGD:6480464
G Ccne2 cyclin E2 JBrowse link 4 11,190,433 11,204,779 RGD:6480464
G Cdk2 cyclin-dependent kinase 2 JBrowse link 10 128,697,938 128,705,051 RGD:6480464
G Cdk3 cyclin-dependent kinase 3 JBrowse link 11 116,216,002 116,220,287 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 10 127,063,535 127,067,288 RGD:6480464
G Cdk5 cyclin-dependent kinase 5 JBrowse link 5 24,407,597 24,423,587 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 5 3,341,004 3,531,008 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:6480464
G Cdkn2b cyclin dependent kinase inhibitor 2B JBrowse link 4 89,306,289 89,311,032 RGD:6480464
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha JBrowse link 7 35,119,293 35,121,928 RGD:6480464
G Ciita class II transactivator JBrowse link 16 10,480,014 10,531,064 RGD:6480464
G Crot carnitine O-octanoyltransferase JBrowse link 5 8,966,033 8,997,146 RGD:6480464
G Cxcl1 chemokine (C-X-C motif) ligand 1 JBrowse link 5 90,891,245 90,893,121 RGD:6480464
G Cxcl10 chemokine (C-X-C motif) ligand 10 JBrowse link 5 92,346,638 92,348,889 RGD:6480464
G Cxcl12 chemokine (C-X-C motif) ligand 12 JBrowse link 6 117,168,535 117,181,368 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cxcl2 chemokine (C-X-C motif) ligand 2 JBrowse link 5 90,903,899 90,905,938 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 5 90,786,101 90,788,093 RGD:6480464
G Cxcl5 chemokine (C-X-C motif) ligand 5 JBrowse link 5 90,759,298 90,761,625 RGD:6480464
G Cyb5r3 cytochrome b5 reductase 3 JBrowse link 15 83,153,495 83,176,440 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 JBrowse link 19 39,287,044 39,330,713 RGD:6480464
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 JBrowse link 19 39,389,556 39,463,103 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 JBrowse link 15 82,370,527 82,380,260 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 JBrowse link 5 137,892,933 137,925,610 RGD:6480464
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 JBrowse link 4 115,624,698 115,647,721 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 5 4,080,674 4,104,697 RGD:6480464
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 JBrowse link 4 6,265,612 6,275,632 RGD:6480464
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 JBrowse link 9 121,914,356 121,916,305 RGD:6480464
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 7 143,823,167 143,848,410 RGD:6480464
G E2f1 E2F transcription factor 1 JBrowse link 2 154,559,400 154,569,892 RGD:6480464
G E2f2 E2F transcription factor 2 JBrowse link 4 136,172,274 136,196,057 RGD:6480464
G E2f3 E2F transcription factor 3 JBrowse link 13 29,906,575 29,986,064 RGD:6480464
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase JBrowse link 16 21,761,285 21,787,834 RGD:6480464
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:6480464
G Fasl Fas ligand (TNF superfamily, member 6) JBrowse link 1 161,780,691 161,788,495 RGD:6480464
G Fasn fatty acid synthase JBrowse link 11 120,805,958 120,825,166 RGD:6480464
G Fgf15 fibroblast growth factor 15 JBrowse link 7 144,896,532 144,900,953 RGD:6480464
G Fos FBJ osteosarcoma oncogene JBrowse link 12 85,473,890 85,477,274 RGD:6480464
G Glb1 galactosidase, beta 1 JBrowse link 9 114,401,078 114,474,379 RGD:6480464
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) JBrowse link 15 99,717,587 99,725,014 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 JBrowse link 12 110,691,036 110,696,395 RGD:6480464
G Hsph1 heat shock 105kDa/110kDa protein 1 JBrowse link 5 149,616,843 149,636,498 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Il7 interleukin 7 JBrowse link 3 7,572,028 7,613,760 RGD:6480464
G Ins1 insulin I JBrowse link 19 52,264,297 52,265,015 RGD:6480464
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:6480464
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:6480464
G Lif leukemia inhibitory factor JBrowse link 11 4,257,568 4,272,514 RGD:6480464
G Lmna lamin A JBrowse link 3 88,481,148 88,509,932 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 8 68,880,555 68,906,932 RGD:6480464
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Nlrc5 NLR family, CARD domain containing 5 JBrowse link 8 94,434,335 94,527,272 RGD:6480464
G Nos3 nitric oxide synthase 3, endothelial cell JBrowse link 5 24,364,816 24,384,474 RGD:6480464
G Notch4 notch 4 JBrowse link 17 34,564,286 34,588,543 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 16 38,248,349 38,294,849 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 6 5,168,090 5,193,987 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 11 107,933,387 108,343,888 RGD:6480464
G Psma1 proteasome subunit alpha 1 JBrowse link 7 114,264,550 114,276,116 RGD:6480464
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 JBrowse link 11 97,703,434 97,713,500 RGD:6480464
G Psmb5 proteasome (prosome, macropain) subunit, beta type 5 JBrowse link 14 54,614,120 54,617,995 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 14 73,192,858 73,325,951 RGD:6480464
G Rbl1 RB transcriptional corepressor like 1 JBrowse link 2 157,145,893 157,204,534 RGD:6480464
G Rbl2 RB transcriptional corepressor like 2 JBrowse link 8 91,070,057 91,123,844 RGD:6480464
G Rel reticuloendotheliosis oncogene JBrowse link 11 23,736,847 23,770,969 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Scarb1 scavenger receptor class B, member 1 JBrowse link 5 125,277,087 125,341,094 RGD:6480464
G Scp2 sterol carrier protein 2, liver JBrowse link 4 108,043,830 108,144,971 RGD:6480464
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 JBrowse link 12 80,953,185 80,968,705 RGD:6480464
G Slc51a solute carrier family 51, alpha subunit JBrowse link 16 32,475,578 32,487,879 RGD:6480464
G Src Rous sarcoma oncogene JBrowse link 2 157,423,906 157,471,838 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 11 60,199,084 60,224,186 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 11 100,886,806 100,939,594 RGD:6480464
G Tjp1 tight junction protein 1 JBrowse link 7 65,296,165 65,527,850 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 JBrowse link 1 88,211,959 88,220,002 RGD:6480464
G Zmpste24 zinc metallopeptidase, STE24 JBrowse link 4 121,059,237 121,098,249 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21025
    role 21006
      application 20434
        pharmaceutical 20044
          drug 20044
            nutraceutical 9748
              L-valine 112
                L-valine derivative 112
                  GI254023X 0
                  L-valine 2-naphthylamide 0
                  L-valyl ester + 0
                  N,N-dihydroxy-L-valine 0
                  N-acetyl-L-valine + 0
                  elbasvir + 0
                  hydroxy-L-valine + 0
                  ledipasvir + 0
                  ritonavir + 112
                  velpatasvir + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21025
    subatomic particle 21019
      composite particle 21019
        hadron 21019
          baryon 21019
            nucleon 21019
              atomic nucleus 21019
                atom 21019
                  main group element atom 20860
                    p-block element atom 20860
                      carbon group element atom 20601
                        carbon atom 20578
                          organic molecular entity 20578
                            organic group 19174
                              organic divalent group 19164
                                organodiyl group 19164
                                  carbonyl group 19134
                                    carbonyl compound 19134
                                      carboxylic acid 18814
                                        amino acid 12665
                                          alpha-amino acid 7793
                                            L-alpha-amino acid 7445
                                              pyruvate family amino acid 236
                                                L-valine 112
                                                  L-valine derivative 112
                                                    GI254023X 0
                                                    L-valine 2-naphthylamide 0
                                                    L-valyl ester + 0
                                                    N,N-dihydroxy-L-valine 0
                                                    N-acetyl-L-valine + 0
                                                    elbasvir + 0
                                                    hydroxy-L-valine + 0
                                                    ledipasvir + 0
                                                    ritonavir + 112
                                                    velpatasvir + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.