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ONTOLOGY REPORT - ANNOTATIONS


Term:L-valine derivative
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Accession:CHEBI:84129 term browser browse the term
Definition:A proteinogenic amino acid derivative resulting from reaction of L-valine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-valine by a heteroatom.
Synonyms:related_synonym: L-valine derivatives


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ritonavir term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ABCB11 ATP binding cassette subfamily B member 11 JBrowse link 2 168,915,468 169,031,396 RGD:6480464
G ABCB4 ATP binding cassette subfamily B member 4 JBrowse link 7 87,398,988 87,476,722 RGD:6480464
G ACSS2 acyl-CoA synthetase short chain family member 2 JBrowse link 20 34,874,942 34,927,966 RGD:6480464
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 186,842,710 186,858,463 RGD:6480464
G ALB albumin JBrowse link 4 73,404,287 73,421,482 RGD:6480464
G BAK1 BCL2 antagonist/killer 1 JBrowse link 6 33,572,552 33,580,296 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6480464
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 78,214,253 78,225,635 RGD:6480464
G CASP1 caspase 1 JBrowse link 11 105,025,443 105,035,591 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CCL20 C-C motif chemokine ligand 20 JBrowse link 2 227,813,842 227,817,556 RGD:6480464
G CCL3 C-C motif chemokine ligand 3 JBrowse link 17 36,088,256 36,090,143 RGD:6480464
G CCL4 C-C motif chemokine ligand 4 JBrowse link 17 36,103,827 36,105,614 RGD:6480464
G CCNA2 cyclin A2 JBrowse link 4 121,816,444 121,823,883 RGD:6480464
G CCNB1 cyclin B1 JBrowse link 5 69,167,010 69,178,245 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CCND2 cyclin D2 JBrowse link 12 4,273,762 4,305,353 RGD:6480464
G CCNE2 cyclin E2 JBrowse link 8 94,880,224 94,896,671 RGD:6480464
G CDK2 cyclin dependent kinase 2 JBrowse link 12 55,966,830 55,972,789 RGD:6480464
G CDK3 cyclin dependent kinase 3 JBrowse link 17 76,000,906 76,005,999 RGD:6480464
G CDK4 cyclin dependent kinase 4 JBrowse link 12 57,747,727 57,752,310 RGD:6480464
G CDK5 cyclin dependent kinase 5 JBrowse link 7 151,053,815 151,057,897 RGD:6480464
G CDK6 cyclin dependent kinase 6 JBrowse link 7 92,604,921 92,836,573 RGD:6480464
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:6480464
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,270 12,722,383 RGD:6480464
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 9 22,002,903 22,009,313 RGD:6480464
G CEBPA CCAAT enhancer binding protein alpha JBrowse link 19 33,299,934 33,302,564 RGD:6480464
G CIITA class II major histocompatibility complex transactivator JBrowse link 16 10,866,208 10,941,562 RGD:6480464
G CROT carnitine O-octanoyltransferase JBrowse link 7 87,345,646 87,399,794 RGD:6480464
G CXCL1 C-X-C motif chemokine ligand 1 JBrowse link 4 73,869,393 73,871,308 RGD:6480464
G CXCL10 C-X-C motif chemokine ligand 10 JBrowse link 4 76,021,118 76,023,497 RGD:6480464
G CXCL12 C-X-C motif chemokine ligand 12 JBrowse link 10 44,292,088 44,385,097 RGD:6480464
G CXCL2 C-X-C motif chemokine ligand 2 JBrowse link 4 74,097,040 74,099,195 RGD:6480464
G CXCL5 C-X-C motif chemokine ligand 5 JBrowse link 4 73,995,642 73,998,677 RGD:6480464
G CXCL6 C-X-C motif chemokine ligand 6 JBrowse link 4 73,836,678 73,838,760 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G CYB5R3 cytochrome b5 reductase 3 JBrowse link 22 42,617,840 42,649,392 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 JBrowse link 10 94,762,681 94,855,547 RGD:6480464
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 JBrowse link 10 95,036,772 95,069,497 RGD:6480464
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 JBrowse link 10 94,938,658 94,990,091 RGD:6480464
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 JBrowse link 22 42,126,499 42,130,810 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 JBrowse link 7 99,648,194 99,679,996 RGD:6480464
G CYP4B1 cytochrome P450 family 4 subfamily B member 1 JBrowse link 1 46,799,046 46,819,413 RGD:6480464
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 JBrowse link 7 92,112,149 92,134,745 RGD:6480464
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 8 58,490,178 58,500,163 RGD:6480464
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 JBrowse link 3 42,872,192 42,875,879 RGD:6480464
G DHCR7 7-dehydrocholesterol reductase JBrowse link 11 71,434,411 71,448,393 RGD:6480464
G E2F1 E2F transcription factor 1 JBrowse link 20 33,675,477 33,686,385 RGD:6480464
G E2F2 E2F transcription factor 2 JBrowse link 1 23,505,696 23,531,250 RGD:6480464
G E2F3 E2F transcription factor 3 JBrowse link 6 20,401,879 20,493,714 RGD:6480464
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase JBrowse link 3 185,190,624 185,254,049 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G FASLG Fas ligand JBrowse link 1 172,659,008 172,666,876 RGD:6480464
G FASN fatty acid synthase JBrowse link 17 82,078,338 82,098,303 RGD:6480464
G FGF19 fibroblast growth factor 19 JBrowse link 11 69,698,238 69,704,022 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 14 75,278,828 75,282,230 RGD:6480464
G GLB1 galactosidase beta 1 JBrowse link 3 32,996,608 33,097,230 RGD:6480464
G GPD1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 12 50,104,008 50,111,313 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HSP90AA1 heat shock protein 90 alpha family class A member 1 JBrowse link 14 102,080,742 102,139,749 RGD:6480464
G HSPH1 heat shock protein family H (Hsp110) member 1 JBrowse link 13 31,134,973 31,162,388 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6480464
G IL32 interleukin 32 JBrowse link 16 3,065,403 3,069,530 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G IL7 interleukin 7 JBrowse link 8 78,675,870 78,806,830 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G LEP leptin JBrowse link 7 128,241,201 128,257,629 RGD:6480464
G LIF LIF interleukin 6 family cytokine JBrowse link 22 30,240,453 30,257,487 RGD:6480464
G LMNA lamin A/C JBrowse link 1 156,082,546 156,140,089 RGD:6480464
G LPL lipoprotein lipase JBrowse link 8 19,939,253 19,967,259 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,735,434 127,742,951 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 4 102,501,266 102,617,302 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G NLRC5 NLR family CARD domain containing 5 JBrowse link 16 56,989,547 57,083,524 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G NOTCH4 notch receptor 4 JBrowse link 6 32,194,843 32,224,067 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PON1 paraoxonase 1 JBrowse link 7 95,297,676 95,324,532 RGD:6480464
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,287,485 12,434,344 RGD:6480464
G PRKCA protein kinase C alpha JBrowse link 17 66,302,613 66,810,743 RGD:6480464
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:6480464
G PSMB3 proteasome 20S subunit beta 3 JBrowse link 17 38,752,741 38,764,225 RGD:6480464
G PSMB5 proteasome 20S subunit beta 5 JBrowse link 14 23,025,851 23,035,220 RGD:6480464
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,303,747 48,481,890 RGD:6480464
G RBL1 RB transcriptional corepressor like 1 JBrowse link 20 36,996,349 37,096,029 RGD:6480464
G RBL2 RB transcriptional corepressor like 2 JBrowse link 16 53,434,471 53,491,648 RGD:6480464
G REL REL proto-oncogene, NF-kB subunit JBrowse link 2 60,881,521 60,931,612 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G SCARB1 scavenger receptor class B member 1 JBrowse link 12 124,776,856 124,863,864 RGD:6480464
G SCP2 sterol carrier protein 2 JBrowse link 1 52,927,229 53,051,698 RGD:6480464
G SLC10A1 solute carrier family 10 member 1 JBrowse link 14 69,775,416 69,797,241 RGD:6480464
G SLC51A solute carrier family 51 subunit alpha JBrowse link 3 196,216,534 196,233,427 RGD:6480464
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 37,344,685 37,405,432 RGD:6480464
G SREBF1 sterol regulatory element binding transcription factor 1 JBrowse link 17 17,811,334 17,837,017 RGD:6480464
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:6480464
G TJP1 tight junction protein 1 JBrowse link 15 29,699,367 29,969,049 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 2 233,760,270 233,773,300 RGD:6480464
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 1 40,258,078 40,294,180 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23758
    role 23647
      application 23047
        pharmaceutical 22602
          drug 22602
            nutraceutical 9964
              L-valine 111
                L-valine derivative 111
                  GI254023X 0
                  L-valine 2-naphthylamide 0
                  L-valyl ester + 0
                  N,N-dihydroxy-L-valine 0
                  N-acetyl-L-valine + 0
                  elbasvir + 0
                  hydroxy-L-valine + 0
                  ledipasvir + 0
                  ritonavir + 111
                  velpatasvir + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23758
    subatomic particle 23707
      composite particle 23707
        hadron 23707
          baryon 23707
            nucleon 23707
              atomic nucleus 23707
                atom 23707
                  main group element atom 23527
                    p-block element atom 23527
                      carbon group element atom 23238
                        carbon atom 23215
                          organic molecular entity 23215
                            organic group 21900
                              organic divalent group 21872
                                organodiyl group 21872
                                  carbonyl group 21843
                                    carbonyl compound 21843
                                      carboxylic acid 20891
                                        amino acid 13055
                                          alpha-amino acid 7883
                                            L-alpha-amino acid 7534
                                              pyruvate family amino acid 234
                                                L-valine 111
                                                  L-valine derivative 111
                                                    GI254023X 0
                                                    L-valine 2-naphthylamide 0
                                                    L-valyl ester + 0
                                                    N,N-dihydroxy-L-valine 0
                                                    N-acetyl-L-valine + 0
                                                    elbasvir + 0
                                                    hydroxy-L-valine + 0
                                                    ledipasvir + 0
                                                    ritonavir + 111
                                                    velpatasvir + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.