Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:8412 term browser browse the term
Definition:A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Synonyms:exact_synonym: 5-ethyl-5-phenyldihydropyrimidine-4,6(1H,5H)-dione
 related_synonym: 2-deoxyphenobarbital;   5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione;   Formula=C12H14N2O2;   InChI=1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16);   InChIKey=DQMZLTXERSFNPB-UHFFFAOYSA-N;   SMILES=CCC1(C(=O)NCNC1=O)c1ccccc1;   primidona;   primidonum
 xref: CAS:125-33-7;   DrugBank:DB00794;   Drug_Central:2267;   HMDB:HMDB0014932;   KEGG:C07371;   KEGG:D00474;   LINCS:LSM-2700
 xref_mesh: MESH:D011324
 xref: PMID:10716065;   PMID:17253477;   PMID:24712318;   PMID:24812533;   Reaxys:218034;   Wikipedia:Primidone

show annotations for term's descendants       view all columns           Sort by:
primidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:6480464
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      biological role 19726
        xenobiotic 18408
          primidone 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic molecule 19472
                              organic cyclic compound 19236
                                organic heterocyclic compound 18361
                                  organic heteromonocyclic compound 16452
                                    diazines 12162
                                      pyrimidines 11979
                                        pyrimidone 8769
                                          primidone 5
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.