Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antazoline
go back to main search page
Accession:CHEBI:84115 term browser browse the term
Definition:A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.
Synonyms:exact_synonym: N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
 related_synonym: 2-(N-Benzylanilinomethyl)-2-imidazoline;   2-(N-Phenyl-N-benzylaminomethyl)imidazoline;   4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine;   Formula=C17H19N3;   InChI=1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19);   InChIKey=REYFJDPCWQRWAA-UHFFFAOYSA-N;   SMILES=C(N(Cc1ccccc1)c1ccccc1)C1=NCCN1;   antazolina;   antazolinum
 xref: CAS:91-75-8;   DrugBank:DB08799;   Drug_Central:224;   HMDB:HMDB0015689;   KEGG:D07458;   LINCS:LSM-6023
 xref_mesh: MESH:D000865
 xref: PMID:1180129;   PMID:16394564;   PMID:22967497;   PMID:23669609;   PMID:23847054;   PMID:23990192;   PMID:3793827;   PMID:5792228;   PMID:712601;   PMID:7199833;   PMID:9145778;   Reaxys:233924;   Wikipedia:Antazoline



show annotations for term's descendants           Sort by:
 
antazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Antazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions
ISO Antazoline results in increased activity of TAAR1 protein
[Antazoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP
CTD PMID:19725810 NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        xenobiotic 18664
          antazoline 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    main group molecular entity 19956
                      s-block molecular entity 19752
                        hydrogen molecular entity 19745
                          hydrides 19114
                            inorganic hydride 17882
                              pnictogen hydride 17865
                                nitrogen hydride 17754
                                  azane 17503
                                    ammonia 17502
                                      organic amino compound 17502
                                        tertiary amino compound 8848
                                          antazoline 2
paths to the root