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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pentose phosphate
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Accession:CHEBI:84055 term browser browse the term
Definition:Any phospho sugar that is the phosphate derivative of pentose.
Synonyms:related_synonym: pentose phosphates


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2'-deoxycytosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Deoxycytidine Monophosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
2'-deoxyguanosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial increases abundance
multiple interactions
EXP IDH2 protein mutant form results in increased abundance of 2'-deoxyguanosine 5'-phosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 2'-deoxyguanosine 5'-phosphate]
CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
2-deoxy-alpha-D-ribose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase increases abundance ISO TYMP protein results in increased abundance of 2-deoxyribose 1-phosphate CTD PMID:11103787 NCBI chr15:89,371,631...89,377,036
Ensembl chr15:89,371,931...89,377,039
JBrowse link
2-deoxy-D-ribofuranose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase increases abundance ISO TYMP protein results in increased abundance of 2-deoxyribose 1-phosphate CTD PMID:11103787 NCBI chr15:89,371,631...89,377,036
Ensembl chr15:89,371,931...89,377,039
JBrowse link
3',5'-cyclic AMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 increases expression
multiple interactions
EXP Cyclic AMP results in increased expression of ABCA1 mRNA; Cyclic AMP results in increased expression of ABCA1 protein
[HCAR2 protein results in decreased abundance of Cyclic AMP] which results in decreased expression of ABCA1 protein
CTD PMID:20339114 PMID:20655299 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 increases transport
multiple interactions
affects uptake
ISO
EXP
ABCC4 protein results in increased transport of Cyclic AMP
Probenecid affects the reaction [ABCC4 protein affects the uptake of Cyclic AMP analog]
CTD PMID:11856762 PMID:28587784 NCBI chr14:118,482,692...118,707,856
Ensembl chr14:118,482,692...118,706,219
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 multiple interactions ISO [ADCYAP1 protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:7733904 NCBI chr17:93,198,245...93,206,541
Ensembl chr17:93,199,017...93,206,537
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases abundance ISO ADIPOQ protein results in increased abundance of Cyclic AMP CTD PMID:18931039 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Adm adrenomedullin multiple interactions
increases abundance
ISO ADM protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]
ADM protein results in increased abundance of Cyclic AMP; ADM results in increased abundance of Cyclic AMP
CTD PMID:10374718 PMID:17306419 NCBI chr 7:110,627,657...110,629,820
Ensembl chr 7:110,627,661...110,629,820
JBrowse link
G Adra1b adrenergic receptor, alpha 1b multiple interactions EXP ADRA1B protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP] CTD PMID:12649302 NCBI chr11:43,774,605...43,901,250
Ensembl chr11:43,774,606...43,901,210
JBrowse link
G Adrb1 adrenergic receptor, beta 1 multiple interactions
increases abundance
affects abundance
ISO [3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Acebutolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Alprenolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Atenolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Atenolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Bupranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [carvedilol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [carvedilol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP; [CGP 12177 binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [CGP 12177 co-treated with ADRB1] results in increased abundance of Cyclic AMP; [CGP 20712A binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Epinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Formoterol Fumarate binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [ICI 118551 binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Labetalol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [Metoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Norepinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Propranolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Propranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [Salmeterol Xinafoate binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; ADRB1 protein polymorphism affects the reaction [[carvedilol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP]; Alprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bupranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; carvedilol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[Acebutolol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[carvedilol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[CGP 12177 co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[Labetalol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; Isoproterenol promotes the reaction [ADRB1 protein results in increased abundance of Cyclic AMP]; Metoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Nadolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Oxprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Pindolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Sotalol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Timolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]
ADRB1 protein affects the abundance of Cyclic AMP; ADRB1 protein polymorphism affects the abundance of Cyclic AMP
ADRB1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
CTD PMID:11562432 PMID:12761341 PMID:14502278 PMID:14730417 PMID:15060759 PMID:17200720 PMID:18378355 PMID:18787115 PMID:19419905 NCBI chr19:56,722,117...56,725,150
Ensembl chr19:56,722,199...56,733,113
JBrowse link
G Adrb2 adrenergic receptor, beta 2 multiple interactions
increases chemical synthesis
increases abundance
affects abundance
ISO [Terbutaline results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
ADRB2 protein polymorphism results in increased chemical synthesis of Cyclic AMP; ADRB2 protein results in increased chemical synthesis of Cyclic AMP
[Acebutolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Alprenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Atenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Atenolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Betaxolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [BRL 37344 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [broxaterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [carvedilol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [carvedilol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [CGP 12177 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [CGP 20712A binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Formoterol Fumarate binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [ICI 118551 binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [ICI 118551 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Isoproterenol results in increased activity of ADRB2 protein] which results in increased chemical synthesis of Cyclic AMP; [Labetalol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Metaproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Metoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Metoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Nadolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Norepinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Oxprenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Practolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Propranolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Salmeterol Xinafoate binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Sotalol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Timolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; Atenolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]
ADRB2 protein results in increased abundance of Cyclic AMP
ADRB2 protein affects the abundance of Cyclic AMP
CTD PMID:10516654 PMID:10857765 PMID:10952688 PMID:11562432 PMID:12920204 PMID:14730417 PMID:16036225 PMID:16980553 PMID:17925438 PMID:18378355 PMID:19419905 PMID:21868359 PMID:27825928 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
G Adrb3 adrenergic receptor, beta 3 multiple interactions
affects abundance
ISO 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP]; [Albuterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Alprenolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [broxaterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [CGP 12177 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [CGP 20712A binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; [Epinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Formoterol Fumarate binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [ICI 118551 binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Norepinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Salmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; [SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP
ADRB3 protein affects the abundance of Cyclic AMP
CTD PMID:10952688 PMID:14730417 NCBI chr 8:27,225,776...27,230,845
Ensembl chr 8:27,225,776...27,250,616
JBrowse link
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of AHCYL1 mRNA] CTD PMID:19414516 NCBI chr 3:107,663,120...107,696,560
Ensembl chr 3:107,663,118...107,696,560
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
decreases expression
ISO AHR protein promotes the reaction [Cyclic AMP results in increased expression of CYP1B1 mRNA]; Cyclic AMP inhibits the reaction [AHR protein binds to ARNT protein]; Cyclic AMP promotes the reaction [AHR protein binds to CYP1B1 enhancer]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA
Cyclic AMP results in decreased expression of AHR protein
CTD PMID:12859982 PMID:32781018 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ANGPTL4 mRNA] CTD PMID:19414516 NCBI chr17:33,774,900...33,781,575
Ensembl chr17:33,773,750...33,781,830
JBrowse link
G Ank2 ankyrin 2, brain multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ANK2 mRNA] CTD PMID:19414516 NCBI chr 3:126,921,607...127,500,347
Ensembl chr 3:126,921,612...127,499,350
JBrowse link
G Aqp3 aquaporin 3 multiple interactions
increases expression
ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of AQP3 mRNA]; N-(2-aminoethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of AQP3 mRNA] CTD PMID:12542607 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Aqp5 aquaporin 5 multiple interactions EXP Chloroquine inhibits the reaction [Cyclic AMP results in decreased expression of AQP5 protein]; Cyclic AMP affects the expression of and results in increased phosphorylation of and results in increased localization of AQP5 protein CTD PMID:15536076 NCBI chr15:99,591,028...99,594,829
Ensembl chr15:99,590,782...99,594,829
JBrowse link
G Armh4 armadillo-like helical domain containing 4 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ARMH4 mRNA] CTD PMID:19414516 NCBI chr14:49,681,560...49,783,480
Ensembl chr14:49,675,952...49,783,383
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Cyclic AMP inhibits the reaction [AHR protein binds to ARNT protein] CTD PMID:12859982 NCBI chr 3:95,434,367...95,497,240
Ensembl chr 3:95,434,388...95,497,240
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [ARRB2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] which affects the localization of ARRB2 protein CTD PMID:25191754 NCBI chr11:70,432,485...70,440,828
Ensembl chr11:70,432,635...70,440,828
JBrowse link
G Atf5 activating transcription factor 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ATF5 mRNA] CTD PMID:19414516 NCBI chr 7:44,812,256...44,816,658
Ensembl chr 7:44,812,256...44,816,658
JBrowse link
G Avp arginine vasopressin multiple interactions ISO [AVP protein binds to and results in increased activity of AVPR2 protein mutant form] which results in increased abundance of Cyclic AMP; [AVP protein binds to and results in increased activity of AVPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:20683494 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554
JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions ISO [AVP protein binds to and results in increased activity of AVPR2 protein mutant form] which results in increased abundance of Cyclic AMP; [AVP protein binds to and results in increased activity of AVPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:20683494 NCBI chr  X:73,891,765...73,894,428
Ensembl chr  X:73,892,102...73,895,502
JBrowse link
G Braf Braf transforming gene increases activity
multiple interactions
ISO Cyclic AMP results in increased activity of BRAF protein
[Pentoxifylline results in increased abundance of Cyclic AMP] which results in increased activity of BRAF protein; [Theophylline results in increased abundance of Cyclic AMP] which results in increased activity of BRAF protein
CTD PMID:21693435 NCBI chr 6:39,603,231...39,725,658
Ensembl chr 6:39,603,237...39,725,463
JBrowse link
G C130074G19Rik RIKEN cDNA C130074G19 gene multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RGD1310587 mRNA] CTD PMID:19414516 NCBI chr 1:184,871,926...184,883,036
Ensembl chr 1:184,871,926...184,883,218
JBrowse link
G C1qtnf5 C1q and tumor necrosis factor related protein 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of C1QTNF5 mRNA] CTD PMID:19414516 NCBI chr 9:44,101,770...44,109,187
Ensembl chr 9:44,107,245...44,109,187
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases abundance
multiple interactions
ISO CALCA protein modified form results in increased abundance of Cyclic AMP; CALCA protein results in increased abundance of Cyclic AMP
CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]
Isoflurane inhibits the reaction [CALCA protein modified form results in increased abundance of Cyclic AMP]; sevoflurane inhibits the reaction [CALCA protein modified form results in increased abundance of Cyclic AMP]
CTD PMID:15297469 PMID:17295025 PMID:17306419 PMID:18463244 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 multiple interactions
increases phosphorylation
ISO [Cyclic AMP results in increased phosphorylation of CARM1 protein] promotes the reaction [CARM1 protein binds to ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased expression of TFF1 mRNA]; Cyclic AMP promotes the reaction [CARM1 protein binds to ESR1 protein]; Cyclic AMP promotes the reaction [CARM1 protein binds to TFF1 promoter] CTD PMID:20360387 NCBI chr 9:21,546,894...21,589,467
Ensembl chr 9:21,546,894...21,592,623
JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions EXP CCKBR protein affects the reaction [[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP] CTD PMID:11880531 NCBI chr 7:105,425,676...105,436,339
Ensembl chr 7:105,425,731...105,470,898
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 multiple interactions EXP Cyclic AMP inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:9863660 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CCN2 mRNA] CTD PMID:19414516 NCBI chr10:24,595,442...24,598,683
Ensembl chr10:24,595,442...24,598,683
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein; Sorafenib inhibits the reaction [[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein] CTD PMID:21693435 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide decreases phosphorylation EXP Cyclic AMP results in decreased phosphorylation of CD3E protein CTD PMID:2824607 NCBI chr 9:44,998,735...45,009,663
Ensembl chr 9:44,998,740...45,009,627
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide decreases phosphorylation EXP Cyclic AMP results in decreased phosphorylation of CD3G protein CTD PMID:2824607 NCBI chr 9:44,969,572...44,980,431
Ensembl chr 9:44,969,572...44,980,431
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Pentoxifylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein; [Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein; sorafenib inhibits the reaction [[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein] CTD PMID:21693435 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta increases response to substance EXP CEBPB protein results in increased susceptibility to Cyclic AMP CTD PMID:23097472 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions
increases activity
ISO
EXP
Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates]; Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Chlorides]
CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Cyclic AMP affects the localization of and results in increased activity of CFTR protein; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]; Nocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]; Primaquine inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]
Cyclic AMP results in increased activity of CFTR protein
Genistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form]
CTD PMID:11786964 PMID:12529251 PMID:12556293 PMID:12612912 PMID:15229107 PMID:15371258 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Cga glycoprotein hormones, alpha subunit multiple interactions
affects secretion
increases abundance
ISO
EXP
[Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of CGA mRNA
CGA protein affects the secretion of Cyclic AMP
CGA protein results in increased abundance of Cyclic AMP
[CGA protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; [CGA protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Cyclic AMP; [CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Colforsin promotes the reaction [CGA protein results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]
[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]; ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]
CTD PMID:8404651 PMID:20378682 PMID:21642635 PMID:23071612 PMID:26895433 PMID:31132478 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CHSY1 mRNA] CTD PMID:19414516 NCBI chr 7:66,109,492...66,173,798
Ensembl chr 7:66,109,515...66,173,798
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) multiple interactions ISO [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP
(1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP; [Dronabinol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR1 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]
CTD PMID:10422789 PMID:11730719 PMID:17953657 PMID:27429655 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) multiple interactions ISO (1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR2 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]] CTD PMID:17558435 PMID:27429655 NCBI chr 4:135,895,189...135,920,219
Ensembl chr 4:135,895,394...135,920,207
JBrowse link
G Cp ceruloplasmin multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CP mRNA] CTD PMID:19414516 NCBI chr 3:19,956,933...20,009,750
Ensembl chr 3:19,957,054...20,009,145
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [Dexamethasone co-treated with Cyclic AMP] results in increased phosphorylation of CREB1 protein; [Glucagon co-treated with Cyclic AMP] results in increased phosphorylation of CREB1 protein; Cyclic AMP promotes the reaction [CREB1 protein binds to CYP1B1 enhancer] CTD PMID:12859982 PMID:22676303 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO CREBBP protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:20360387 NCBI chr16:4,081,334...4,213,957
Ensembl chr16:4,081,328...4,213,997
JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO [CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP; Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP]
CRH protein inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Cholera Toxin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Manganese results in increased chemical synthesis of Cyclic AMP]; Sphingosine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]
CTD PMID:2153673 PMID:20702571 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 multiple interactions ISO [CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP; Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP] CTD PMID:20702571 NCBI chr11:104,130,463...104,175,523
Ensembl chr11:104,132,855...104,175,523
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions EXP Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of CRP mRNA] CTD PMID:22117073 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) increases expression ISO Cyclic AMP results in increased expression of CSF3 protein CTD PMID:7540958 NCBI chr11:98,700,183...98,703,631
Ensembl chr11:98,701,263...98,703,629
JBrowse link
G Csk c-src tyrosine kinase multiple interactions EXP CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]; CSK protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; CSK protein promotes the reaction [Terbutaline results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr 9:57,626,646...57,653,631
Ensembl chr 9:57,626,646...57,653,631
JBrowse link
G Cstb cystatin B multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CSTB mRNA] CTD PMID:19414516 NCBI chr10:78,425,670...78,427,622
Ensembl chr10:78,425,669...78,427,622
JBrowse link
G Ctsa cathepsin A multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CTSA mRNA] CTD PMID:19414516 NCBI chr 2:164,832,872...164,841,032
Ensembl chr 2:164,832,873...164,841,032
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO [Terbutaline results in increased abundance of Cyclic AMP] which results in increased expression of CXCL8 protein CTD PMID:9258252 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP
ISO
Cyclic AMP results in increased expression of CYP11A1 mRNA
Cyclic AMP results in increased expression of CYP11A1 mRNA; Cyclic AMP results in increased expression of CYP11A1 protein
myricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]; quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]
CTD PMID:25576683 PMID:28668616 PMID:29228121 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
[acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein; [acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in increased activity of CYP17A1 protein; [galaxolide co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein; [galaxolide co-treated with Cyclic AMP] results in increased activity of CYP17A1 protein
Cyclic AMP results in increased expression of CYP17A1 mRNA
CTD PMID:23084589 PMID:25576683 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO Cyclic AMP results in increased expression of CYP19A1 mRNA; Cyclic AMP results in increased expression of CYP19A1 protein
[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]
CTD PMID:29228121 PMID:31953017 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA CTD PMID:32781018 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
EXP
ISO
Cyclic AMP results in increased expression of CYP1B1 mRNA; Cyclic AMP results in increased expression of CYP1B1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA
AHR protein promotes the reaction [Cyclic AMP results in increased expression of CYP1B1 mRNA]; Cyclic AMP promotes the reaction [AHR protein binds to CYP1B1 enhancer]; Cyclic AMP promotes the reaction [CREB1 protein binds to CYP1B1 enhancer]
CTD PMID:12859982 PMID:32781018 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 multiple interactions
increases expression
EXP Cyclic AMP promotes the reaction [HNF4A protein binds to CYP2A5 promoter]; Cyclic AMP promotes the reaction [PPARGC1A protein binds to CYP2A5 promoter]; Dactinomycin inhibits the reaction [Cyclic AMP results in increased expression of CYP2A5 mRNA] CTD PMID:12754101 PMID:18602936 NCBI chr 7:26,835,339...26,843,264
Ensembl chr 7:26,835,305...26,843,548
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP Cyclic AMP results in increased expression of CYP51 mRNA CTD PMID:25576683 NCBI chr 5:4,080,674...4,104,697
Ensembl chr 5:4,081,145...4,104,746
JBrowse link
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 decreases expression
decreases activity
ISO Cyclic AMP results in decreased expression of CYP7B1 mRNA
Cyclic AMP results in decreased activity of CYP7B1 protein
CTD PMID:12029625 NCBI chr 3:18,071,944...18,243,890
Ensembl chr 3:18,071,950...18,243,338
JBrowse link
G Dap death-associated protein multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of DAP mRNA] CTD PMID:19414516 NCBI chr15:31,224,385...31,274,338
Ensembl chr15:31,224,314...31,274,341
JBrowse link
G Ddt D-dopachrome tautomerase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of DDT mRNA] CTD PMID:19414516 NCBI chr10:75,771,233...75,773,374
Ensembl chr10:75,771,230...75,773,414
JBrowse link
G Disc1 disrupted in schizophrenia 1 multiple interactions ISO Cyclic AMP inhibits the reaction [DISC1 protein binds to PDE4B protein] CTD PMID:16293762 NCBI chr 8:125,048,767...125,265,143
Ensembl chr 8:125,054,195...125,261,858
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects response to substance ISO DKK1 protein affects the susceptibility to Cyclic AMP CTD PMID:21546446 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases abundance ISO DLD protein results in increased abundance of Cyclic AMP CTD PMID:25981801 NCBI chr12:31,331,562...31,351,471
Ensembl chr12:31,331,277...31,351,453
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]
[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP; A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]; SCH 23390 inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]]; Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]; Spiperone inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]]
CTD PMID:8558425 PMID:15711596 NCBI chr13:54,051,183...54,055,658
Ensembl chr13:54,051,183...54,055,705
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO
EXP
[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]
[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP; CCKBR protein affects the reaction [[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP]
CTD PMID:11880531 PMID:17958328 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions EXP [3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine binds to and results in decreased activity of DRD4 protein] inhibits the reaction [Naloxone results in increased abundance of Cyclic AMP] CTD PMID:15542745 NCBI chr 7:141,291,974...141,296,464
Ensembl chr 7:141,292,006...141,296,464
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA CTD PMID:12767924 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Ehd2 EH-domain containing 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of EHD2 mRNA] CTD PMID:19414516 NCBI chr 7:15,946,963...15,967,535
Ensembl chr 7:15,946,958...15,967,567
JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ENDOD1 mRNA] CTD PMID:19414516 NCBI chr 9:14,353,990...14,381,242
Ensembl chr 9:14,353,990...14,381,507
JBrowse link
G Eno2 enolase 2, gamma neuronal multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ENO2 mRNA] CTD PMID:19414516 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673
JBrowse link
G Epo erythropoietin increases expression ISO Cyclic AMP results in increased expression of EPO protein CTD PMID:18621143 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO Cyclic AMP results in increased expression of ERRFI1 mRNA CTD PMID:1472065 NCBI chr 4:150,853,796...150,868,889
Ensembl chr 4:150,853,919...150,868,892
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
increases activity
ISO [Cyclic AMP results in increased phosphorylation of CARM1 protein] promotes the reaction [CARM1 protein binds to ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; CREBBP protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; Cyclic AMP promotes the reaction [CARM1 protein binds to ESR1 protein]; ESR1 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:19766106 PMID:20360387 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO
EXP
ESR2 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]
[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]; ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]
CTD PMID:19766106 PMID:20378682 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions EXP [C186 65 binds to and results in increased activity of F2R protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [C186 65 binds to and results in increased activity of F2R protein] which results in decreased chemical synthesis of Cyclic AMP CTD PMID:22207716 NCBI chr13:95,601,780...95,618,466
Ensembl chr13:95,601,803...95,618,487
JBrowse link
G F2rl1 coagulation factor II (thrombin) receptor-like 1 multiple interactions ISO Cyclic AMP promotes the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr13:95,511,718...95,525,240
Ensembl chr13:95,511,732...95,525,227
JBrowse link
G F2rl3 coagulation factor II (thrombin) receptor-like 3 multiple interactions EXP [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] which results in decreased chemical synthesis of Cyclic AMP CTD PMID:22207716 NCBI chr 8:72,761,659...72,763,898
Ensembl chr 8:72,761,880...72,763,874
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of FAM20C mRNA] CTD PMID:19414516 NCBI chr 5:138,755,081...138,810,063
Ensembl chr 5:138,754,514...138,810,077
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of FCGR3 mRNA] CTD PMID:19414516 NCBI chr 1:171,051,169...171,065,915
Ensembl chr 1:171,051,174...171,064,935
JBrowse link
G Fdx1 ferredoxin 1 multiple interactions
increases expression
EXP myricetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA]; quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA] CTD PMID:28668616 NCBI chr 9:51,943,023...51,963,602
Ensembl chr 9:51,943,306...51,963,556
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of FIG4 mRNA] CTD PMID:19414516 NCBI chr10:41,188,172...41,303,241
Ensembl chr10:41,188,172...41,303,260
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
ISO
EXP
[Etoposide co-treated with Cyclic AMP] results in increased expression of FOS mRNA
Cyclic AMP results in increased expression of FOS mRNA
CTD PMID:10064622 PMID:10711420 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO
EXP
[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA]
FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]
CTD PMID:26847930 PMID:31953017 NCBI chr 3:52,268,337...52,350,109
Ensembl chr 3:52,268,336...52,353,221
JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions
increases abundance
increases secretion
ISO
EXP
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; [Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of FSHB mRNA; fulvestrant inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; Methoxychlor inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; Octreotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]
FSHB protein results in increased secretion of Cyclic AMP
NOG protein inhibits the reaction [Octreotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]
[FSHB protein co-treated with Testosterone] results in increased chemical synthesis of Cyclic AMP; [FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Benzo(a)pyrene inhibits the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; o,p'-DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]
CTD PMID:8404651 PMID:18535249 PMID:23137853 PMID:23583632 PMID:25549949 PMID:26895433 NCBI chr 2:107,055,986...107,059,651
Ensembl chr 2:107,056,140...107,059,656
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO [CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; [FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Benzo(a)pyrene inhibits the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; o,p'-DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:26895433 NCBI chr17:88,984,952...89,200,675
Ensembl chr17:88,984,952...89,200,675
JBrowse link
G G6pc glucose-6-phosphatase, catalytic multiple interactions ISO
EXP
[Dexamethasone co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA; [Glucagon co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA]
[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]
CTD PMID:22676303 PMID:26847930 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G Gabpb1 GA repeat binding protein, beta 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GABPB1 mRNA] CTD PMID:19414516 NCBI chr 2:126,628,907...126,684,435
Ensembl chr 2:126,627,442...126,676,337
JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GBP2 mRNA] CTD PMID:19414516 NCBI chr 3:142,620,663...142,638,008
Ensembl chr 3:142,620,602...142,638,008
JBrowse link
G Gcg glucagon multiple interactions
increases chemical synthesis
increases abundance
EXP
ISO
[GCG protein modified form binds to and results in increased activity of GLP1R protein] which results in increased abundance of Cyclic AMP
Dietary Fats promotes the reaction [GCG protein results in increased chemical synthesis of Cyclic AMP]; Niclosamide inhibits the reaction [GCG protein results in increased abundance of Cyclic AMP]
[[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [ARRB2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] which affects the localization of ARRB2 protein; [GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP
CTD PMID:6312992 PMID:18669601 PMID:20074626 PMID:25191754 PMID:26964897 NCBI chr 2:62,474,530...62,483,653
Ensembl chr 2:62,474,530...62,483,650
JBrowse link
G Gdnf glial cell line derived neurotrophic factor multiple interactions ISO 3,9-bis((ethylthio)methyl)-K-252a inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium]; [GDNF protein co-treated with Cyclic AMP] results in decreased susceptibility to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; [GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium; Mazindol inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium]; vanoxerine inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium] CTD PMID:19647008 NCBI chr15:7,810,048...7,837,580
Ensembl chr15:7,810,846...7,837,575
JBrowse link
G Ghrh growth hormone releasing hormone multiple interactions ISO [GH-RH(1-29), desaminotyrosyl(1)-ornithyl(12,21)-alpha-aminobutryic acid(15)-norleucyl(27)-aspartyl(28)-agmatine(29)- binds to and results in increased activity of GHRH protein] which results in increased abundance of Cyclic AMP CTD PMID:22308467 NCBI chr 2:157,329,496...157,348,725
Ensembl chr 2:157,329,497...157,347,506
JBrowse link
G Gip gastric inhibitory polypeptide multiple interactions ISO [GIP protein binds to and results in increased activity of GIPR protein] which results in increased chemical synthesis of Cyclic AMP CTD PMID:25191754 NCBI chr11:96,024,532...96,030,831
Ensembl chr11:96,024,545...96,030,831
JBrowse link
G Gipr gastric inhibitory polypeptide receptor multiple interactions ISO [GIP protein binds to and results in increased activity of GIPR protein] which results in increased chemical synthesis of Cyclic AMP CTD PMID:25191754 NCBI chr 7:19,156,063...19,170,248
Ensembl chr 7:19,156,061...19,166,127
JBrowse link
G Glipr2 GLI pathogenesis-related 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GLIPR2 mRNA] CTD PMID:19414516 NCBI chr 4:43,957,702...43,979,118
Ensembl chr 4:43,957,401...43,979,118
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP
ISO
[GCG protein modified form binds to and results in increased activity of GLP1R protein] which results in increased abundance of Cyclic AMP
[[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [ARRB2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] which affects the localization of ARRB2 protein; [GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP
CTD PMID:18669601 PMID:25191754 NCBI chr17:30,901,867...30,936,510
Ensembl chr17:30,901,817...30,940,791
JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 multiple interactions EXP [[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI2] which results in decreased chemical synthesis of Cyclic AMP CTD PMID:20713914 NCBI chr 9:107,614,125...107,635,391
Ensembl chr 9:107,614,125...107,635,367
JBrowse link
G Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type multiple interactions ISO [[GNAL protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP CTD PMID:15598656 NCBI chr18:67,088,298...67,226,792
Ensembl chr18:67,088,216...67,226,792
JBrowse link
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus multiple interactions ISO
EXP
[[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP; GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP]
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP
CTD PMID:11895442 PMID:15598656 PMID:23022524 NCBI chr 2:174,284,320...174,346,744
Ensembl chr 2:174,284,320...174,346,744
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 multiple interactions EXP
ISO
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP
[Chenodeoxycholic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP; [Colforsin binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP; [Lithocholic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP
CTD PMID:17963371 PMID:23022524 NCBI chr 1:74,278,600...74,279,589
Ensembl chr 1:74,278,550...74,279,624
JBrowse link
G Gpc3 glypican 3 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GPC3 mRNA] CTD PMID:19414516 NCBI chr  X:52,272,426...52,613,974
Ensembl chr  X:52,272,426...52,613,950
JBrowse link
G Greb1l growth regulation by estrogen in breast cancer-like multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GREB1L mRNA] CTD PMID:19414516 NCBI chr18:10,324,933...10,562,945
Ensembl chr18:10,325,177...10,562,940
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein] CTD PMID:25191754 NCBI chr19:4,285,999...4,306,222
Ensembl chr19:4,286,001...4,306,222
JBrowse link
G Grn granulin multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GRN mRNA] CTD PMID:19414516 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Gtpbp2 GTP binding protein 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GTPBP2 mRNA] CTD PMID:19414516 NCBI chr17:46,159,227...46,169,370
Ensembl chr17:46,161,032...46,169,370
JBrowse link
G Gypc glycophorin C multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GYPC mRNA] CTD PMID:19414516 NCBI chr18:32,528,320...32,560,034
Ensembl chr18:32,528,322...32,560,034
JBrowse link
G H2bc21 H2B clustered histone 21 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HIST2H2BE mRNA] CTD PMID:19414516 NCBI chr 3:96,221,072...96,223,738
Ensembl chr 3:96,221,119...96,223,738
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 decreases abundance
multiple interactions
ISO
EXP
HCAR3 protein results in decreased abundance of Cyclic AMP
[HCAR2 protein results in decreased abundance of Cyclic AMP] which results in decreased expression of ABCA1 protein; [Niacin binds to and results in increased activity of HCAR2 protein] which results in decreased abundance of Cyclic AMP
CTD PMID:12563315 PMID:19237584 PMID:20655299 NCBI chr 5:123,863,570...123,865,516
Ensembl chr 5:123,863,570...123,865,499
JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HDAC2 mRNA] CTD PMID:19414516 NCBI chr10:36,974,297...37,001,889
Ensembl chr10:36,974,544...37,001,889
JBrowse link
G Hdac6 histone deacetylase 6 affects abundance EXP HDAC6 protein affects the abundance of Cyclic AMP CTD PMID:28887310 NCBI chr  X:7,930,116...7,948,047
Ensembl chr  X:7,930,120...7,947,889
JBrowse link
G Hivep2 human immunodeficiency virus type I enhancer binding protein 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HIVEP2 mRNA] CTD PMID:19414516 NCBI chr10:13,961,609...14,151,378
Ensembl chr10:13,966,075...14,151,374
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha multiple interactions EXP Cyclic AMP promotes the reaction [HNF4A protein binds to CYP2A5 promoter] CTD PMID:18602936 NCBI chr 2:163,506,811...163,572,907
Ensembl chr 2:163,506,808...163,572,910
JBrowse link
G Hp haptoglobin multiple interactions EXP Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of HP mRNA] CTD PMID:22117073 NCBI chr 8:109,575,128...109,579,172
Ensembl chr 8:109,575,128...109,579,172
JBrowse link
G Hrh1 histamine receptor H1 multiple interactions ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in decreased abundance of Cyclic AMP]]; HRH1 protein promotes the reaction [Histamine results in decreased abundance of Cyclic AMP]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in decreased abundance of Cyclic AMP]] CTD PMID:2419744 NCBI chr 6:114,397,936...114,483,298
Ensembl chr 6:114,397,936...114,483,296
JBrowse link
G Hrh2 histamine receptor H2 increases abundance
multiple interactions
ISO HRH2 protein results in increased abundance of Cyclic AMP
[Cimetidine binds to and results in decreased activity of HRH2 protein] which results in decreased abundance of Cyclic AMP; [Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased abundance of Cyclic AMP; [Histamine binds to and results in increased activity of HRH2 protein] which results in increased abundance of Cyclic AMP; Burimamide inhibits the reaction [[Cyclic AMP binds to and results in decreased activity of HRH2 protein] which results in decreased abundance of Cimetidine]; Burimamide inhibits the reaction [[Cyclic AMP binds to and results in increased activity of HRH2 protein] which results in increased abundance of Histamine]; Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12A protein]; Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein]; Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Dinoprostone results in increased abundance of Cyclic AMP]]; HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP]; HRH2 protein promotes the reaction [Dinoprostone results in increased abundance of Cyclic AMP]
CTD PMID:9187264 PMID:9681472 PMID:15843518 NCBI chr13:54,191,970...54,236,182
Ensembl chr13:54,192,129...54,236,180
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO [imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; ciproxifan inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; thioperamide inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:21276809 NCBI chr 2:180,099,465...180,104,484
Ensembl chr 2:180,099,465...180,104,488
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression EXP Cyclic AMP results in increased expression of HSD3B1 mRNA CTD PMID:25576683 NCBI chr 3:98,842,356...98,859,794
Ensembl chr 3:98,852,194...98,859,794
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions ISO [JB-788 binds to and results in increased activity of HTR1A protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Melitten inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11356925 PMID:20580787 NCBI chr13:105,443,693...105,448,133
Ensembl chr13:105,443,639...105,448,122
JBrowse link
G Htr1b 5-hydroxytryptamine (serotonin) receptor 1B multiple interactions ISO HTR1B affects the reaction [almotriptan inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11134654 NCBI chr 9:81,628,291...81,633,832
Ensembl chr 9:81,628,291...81,633,828
JBrowse link
G Htr6 5-hydroxytryptamine (serotonin) receptor 6 increases abundance
multiple interactions
EXP HTR6 protein results in increased abundance of Cyclic AMP
Serotonin promotes the reaction [HTR6 protein results in increased abundance of Cyclic AMP]
CTD PMID:11406289 NCBI chr 4:139,059,706...139,075,570
Ensembl chr 4:139,061,108...139,075,570
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 increases abundance
multiple interactions
ISO HTR7 results in increased abundance of Cyclic AMP
[3,N-dimethyl-N-(1-methyl-3-(4-methylpiperidin-1-yl)propyl)benzenesulfonamide binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [5-carboxamidotryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [5-Methoxytryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [Bromocriptine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Lisuride binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [mesulergine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Methiothepin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Methiothepin binds to and results in decreased activity of HTR7 protein] which results in decreased abundance of Cyclic AMP; [Methoxydimethyltryptamines binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [Mianserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Risperidone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Ritanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Serotonin binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [Spiperone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [volinanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]
CTD PMID:10720076 PMID:14578406 PMID:19509219 NCBI chr19:35,958,415...36,058,133
Ensembl chr19:35,958,734...36,057,507
JBrowse link
G Htra1 HtrA serine peptidase 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HTRA1 mRNA] CTD PMID:19414516 NCBI chr 7:130,936,203...130,985,658
Ensembl chr 7:130,936,111...130,985,660
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Cyclic AMP] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein CTD PMID:32781018 NCBI chr 8:24,584,133...24,596,952
Ensembl chr 8:24,584,136...24,597,009
JBrowse link
G Ier3 immediate early response 3 multiple interactions
affects response to substance
ISO
EXP
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IER3 mRNA]
IER3 protein affects the susceptibility to Cyclic AMP
[[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI2] which results in decreased chemical synthesis of Cyclic AMP; IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Pertussis Toxin affects the reaction [IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]]
CTD PMID:19414516 PMID:20713914 NCBI chr17:35,821,713...35,822,911
Ensembl chr17:35,821,684...35,822,923
JBrowse link
G Ifng interferon gamma multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased abundance of Kynurenine]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased abundance of Kynurenine; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]] CTD PMID:32781018 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO 2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 4-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; NAD inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA] CTD PMID:31953017 PMID:32781018 NCBI chr11:7,197,787...7,202,546
Ensembl chr11:7,197,782...7,202,546
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IGFBP5 mRNA] CTD PMID:19414516 NCBI chr 1:72,858,065...72,874,865
Ensembl chr 1:72,857,932...72,874,884
JBrowse link
G Il12a interleukin 12a multiple interactions ISO Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12A protein] CTD PMID:15843518 NCBI chr 3:68,690,644...68,698,550
Ensembl chr 3:68,690,644...68,698,547
JBrowse link
G Il12b interleukin 12b multiple interactions ISO Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein] CTD PMID:15843518 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il15ra interleukin 15 receptor, alpha chain multiple interactions
decreases expression
EXP [Metformin co-treated with Cyclic AMP] results in decreased expression of IL15RA mRNA; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in decreased expression of IL15RA mRNA] CTD PMID:22117073 NCBI chr 2:11,705,172...11,733,985
Ensembl chr 2:11,705,290...11,734,317
JBrowse link
G Il17re interleukin 17 receptor E multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IL17RE mRNA] CTD PMID:19414516 NCBI chr 6:113,458,699...113,470,758
Ensembl chr 6:113,458,484...113,470,758
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases abundance
ISO
EXP
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]; Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]; Ibuprofen inhibits the reaction [IL1B protein results in increased abundance of Cyclic AMP]; KT 5720 inhibits the reaction [Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]]; KT 5823 inhibits the reaction [Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]]; Rolipram promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]
Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of CRP mRNA]; Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of HP mRNA]; Cyclic AMP promotes the reaction [IL1B protein results in increased expression of IL1RN mRNA]
CTD PMID:8904084 PMID:17709599 PMID:22117073 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression
EXP Cyclic AMP promotes the reaction [IL1B protein results in increased expression of IL1RN mRNA]; Cyclic AMP promotes the reaction [Metformin results in increased expression of IL1RN mRNA]; Metformin promotes the reaction [Cyclic AMP results in increased expression of IL1RN mRNA]; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in increased expression of IL1RN mRNA] CTD PMID:22117073 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il4 interleukin 4 increases chemical synthesis
multiple interactions
ISO IL4 protein results in increased chemical synthesis of Cyclic AMP
Ketoconazole inhibits the reaction [IL4 protein results in increased chemical synthesis of Cyclic AMP]
CTD PMID:12230500 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il6 interleukin 6 increases expression ISO Cyclic AMP analog results in increased expression of IL6 mRNA CTD PMID:10469353 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Inhba inhibin beta-A increases secretion ISO Cyclic AMP results in increased secretion of INHBA protein CTD PMID:20074812 NCBI chr13:16,004,256...16,031,609
Ensembl chr13:16,011,851...16,031,621
JBrowse link
G Ins1 insulin I multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein] CTD PMID:26847930 NCBI chr19:52,264,297...52,265,015
Ensembl chr19:52,264,297...52,265,476
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IQGAP1 mRNA] CTD PMID:19414516 NCBI chr 7:80,711,583...80,815,549
Ensembl chr 7:80,711,583...80,825,974
JBrowse link
G Irf6 interferon regulatory factor 6 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IRF6 mRNA] CTD PMID:19414516 NCBI chr 1:193,153,112...193,172,036
Ensembl chr 1:193,153,111...193,172,023
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ITGB1 mRNA] CTD PMID:19414516 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Etoposide co-treated with Cyclic AMP] results in increased expression of JUN mRNA CTD PMID:10711420 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of KCND2 mRNA] CTD PMID:19414516 NCBI chr 6:21,215,346...21,729,805
Ensembl chr 6:21,215,503...21,729,805
JBrowse link
G Kif15 kinesin family member 15 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of KIF15 mRNA] CTD PMID:19414516 NCBI chr 9:122,951,081...123,018,733
Ensembl chr 9:122,951,046...123,018,733
JBrowse link
G Kng2 kininogen 2 increases abundance ISO KNG1 results in increased abundance of Cyclic AMP CTD PMID:15750287 NCBI chr16:22,985,852...23,029,101
Ensembl chr16:22,985,854...23,029,482
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LAMP1 mRNA] CTD PMID:19414516 NCBI chr 8:13,159,161...13,175,338
Ensembl chr 8:13,159,161...13,175,338
JBrowse link
G Lep leptin increases abundance
multiple interactions
increases expression
ISO
EXP
LEP protein results in increased abundance of Cyclic AMP
3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile inhibits the reaction [Cyclic AMP analog results in increased expression of LEP mRNA]
CTD PMID:11342529 PMID:27381457 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lhb luteinizing hormone beta multiple interactions
increases chemical synthesis
affects secretion
increases abundance
ISO 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [LHB protein results in increased abundance of Cyclic AMP]; [Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP; [Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP; [Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of LHB mRNA; [LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP; CRH protein inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP]; Masoprocol inhibits the reaction [LHB protein results in increased abundance of Cyclic AMP]; Sphingosine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP]
CGB3 protein results in increased chemical synthesis of Cyclic AMP; LHB protein results in increased chemical synthesis of Cyclic AMP
LHB protein affects the secretion of Cyclic AMP
[LHB protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; [LHB protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Cyclic AMP
CTD PMID:2153673 PMID:6430271 PMID:8404651 PMID:23071612 NCBI chr 7:45,417,608...45,421,855
Ensembl chr 7:45,420,820...45,421,897
Ensembl chr 7:45,420,820...45,421,897
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO
EXP
[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP; ESR1 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; ESR2 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]
[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]
CTD PMID:19766106 PMID:20378682 NCBI chr17:88,716,384...88,792,059
Ensembl chr17:88,716,481...88,791,990
JBrowse link
G Lipe lipase, hormone sensitive increases activity ISO Cyclic AMP results in increased activity of LIPE protein CTD PMID:7155675 NCBI chr 7:25,379,527...25,398,486
Ensembl chr 7:25,379,527...25,398,710
JBrowse link
G Lmna lamin A multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LMNA mRNA] CTD PMID:19414516 NCBI chr 3:88,481,148...88,509,932
Ensembl chr 3:88,480,147...88,509,956
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LURAP1L mRNA] CTD PMID:19414516 NCBI chr 4:80,910,686...80,954,301
Ensembl chr 4:80,910,646...80,955,628
JBrowse link
G Man1a mannosidase 1, alpha multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of MAN1A mRNA] CTD PMID:19414516 NCBI chr10:53,904,785...54,076,616
Ensembl chr10:53,904,785...54,076,609
JBrowse link
G Mc2r melanocortin 2 receptor multiple interactions ISO [acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in decreased expression of MC2R mRNA CTD PMID:23084589 NCBI chr18:68,406,899...68,429,320
Ensembl chr18:68,406,907...68,429,320
JBrowse link
G Msantd3 Myb/SANT-like DNA-binding domain containing 3 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of MSANTD3 mRNA] CTD PMID:19414516 NCBI chr 4:48,539,854...48,565,892
Ensembl chr 4:48,539,935...48,561,919
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 increases phosphorylation
multiple interactions
ISO Cyclic AMP results in increased phosphorylation of NDUFB11 protein
Zalcitabine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein]; Zidovudine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein]
CTD PMID:17904600 NCBI chr  X:20,615,326...20,617,619
Ensembl chr  X:20,615,326...20,617,619
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
ISO [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA; [Isoproterenol results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA
Cyclic AMP results in increased expression of NGF mRNA
CTD PMID:2174743 PMID:2853697 NCBI chr 3:102,469,919...102,521,013
Ensembl chr 3:102,469,919...102,521,013
JBrowse link
G Nog noggin multiple interactions EXP NOG protein inhibits the reaction [Octreotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]] CTD PMID:23137853 NCBI chr11:89,300,638...89,302,559
Ensembl chr11:89,300,638...89,302,332
JBrowse link
G Npl N-acetylneuraminate pyruvate lyase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of NPL mRNA] CTD PMID:19414516 NCBI chr 1:153,503,016...153,549,714
Ensembl chr 1:153,503,015...153,550,045
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression
multiple interactions
EXP Cyclic AMP results in decreased expression of NR0B1 mRNA
Verapamil promotes the reaction [Cyclic AMP results in decreased expression of NR0B1 mRNA]
CTD PMID:19822634 NCBI chr  X:86,191,775...86,195,947
Ensembl chr  X:86,191,764...86,195,947
JBrowse link
G Oat ornithine aminotransferase increases activity
multiple interactions
increases expression
ISO Cyclic AMP results in increased activity of OAT protein
Deoxyglucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Dihydroxyacetone inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Fructose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Fructose inhibits the reaction [Cyclic AMP results in increased expression of OAT mRNA]; Galactose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Glucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Glycerol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Inositol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Mannitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Mannose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Rhamnose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Sorbitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Sorbose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Xylitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]
CTD PMID:2824512 PMID:2827574 NCBI chr 7:132,557,475...132,576,398
Ensembl chr 7:132,557,478...132,576,398
JBrowse link
G Olfr49 olfactory receptor 49 multiple interactions EXP
ISO
[citronellal results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP
[[GNAL protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP; [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP
CTD PMID:15598656 NCBI chr14:54,281,896...54,282,925
Ensembl chr14:54,278,253...54,284,939
JBrowse link
G Olfr544 olfactory receptor 544 multiple interactions EXP [azelaic acid results in increased activity of OLFR544 protein] which results in increased abundance of Cyclic AMP; octanoic acid promotes the reaction [[azelaic acid results in increased activity of OLFR544 protein] which results in increased abundance of Cyclic AMP] CTD PMID:15598656 NCBI chr 7:102,484,114...102,488,307
Ensembl chr 7:102,482,031...102,488,313
JBrowse link
G Olfr586 olfactory receptor 586 multiple interactions EXP [pelargonic acid results in increased activity of OLFR586 protein] which results in increased abundance of Cyclic AMP; octanoic acid promotes the reaction [[pelargonic acid results in increased activity of OLFR586 protein] which results in increased abundance of Cyclic AMP] CTD PMID:15598656 NCBI chr 7:103,121,829...103,122,782
Ensembl chr 7:103,118,403...103,125,638
JBrowse link
G Olfr73 olfactory receptor 73 multiple interactions EXP [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP; [Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP CTD PMID:12767924 PMID:15716417 NCBI chr 2:88,034,196...88,035,137
Ensembl chr 2:88,032,288...88,037,699
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [7-benzylidenenaltrexone binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; [[Naloxone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; [[Naltrexone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; [chlornaltrexamine binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; [clocinnamox binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; [nalmefene binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP CTD PMID:11413242 NCBI chr10:6,758,593...7,038,209
Ensembl chr10:6,758,506...7,038,198
JBrowse link
G Os9 amplified in osteosarcoma multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of OS9 mRNA] CTD PMID:19414516 NCBI chr10:127,094,259...127,121,160
Ensembl chr10:127,095,650...127,121,131
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic increases expression
multiple interactions
ISO
EXP
Cyclic AMP results in increased expression of PCK1 mRNA
[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]
[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA; [Glucagon co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]; Hydrogen Peroxide inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]; ochratoxin A inhibits the reaction [Cyclic AMP results in increased expression of PCK1 mRNA]; sodium arsenite inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]
CTD PMID:2569870 PMID:8971075 PMID:10446394 PMID:22117073 PMID:22676303 PMID:26847930 NCBI chr 2:173,153,073...173,159,274
Ensembl chr 2:173,153,048...173,159,273
JBrowse link
G Pde10a phosphodiesterase 10A multiple interactions
increases hydrolysis
ISO Cyclic AMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP]; Cyclic GMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP] CTD PMID:10373451 NCBI chr17:8,525,187...8,986,648
Ensembl chr17:8,525,372...8,986,648
JBrowse link
G Pde11a phosphodiesterase 11A increases hydrolysis ISO PDE11A protein results in increased hydrolysis of Cyclic AMP CTD PMID:10725373 NCBI chr 2:75,985,808...76,339,145
Ensembl chr 2:75,989,141...76,338,774
JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific multiple interactions EXP
ISO
[[S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; [S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP
[Bresol results in decreased activity of PDE4B protein] which results in increased abundance of Cyclic AMP; Cyclic AMP inhibits the reaction [DISC1 protein binds to PDE4B protein]
CTD PMID:16293762 PMID:21266552 PMID:21854221 NCBI chr 4:102,087,332...102,607,275
Ensembl chr 4:102,087,543...102,607,259
JBrowse link
G Pde7a phosphodiesterase 7A multiple interactions
increases hydrolysis
ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; Papaverine inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP] CTD PMID:10618442 PMID:10814504 NCBI chr 3:19,223,108...19,311,322
Ensembl chr 3:19,223,108...19,311,322
JBrowse link
G Pde7b phosphodiesterase 7B increases hydrolysis
multiple interactions
ISO
EXP
PDE7B protein results in increased hydrolysis of Cyclic AMP
1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; E 4021 inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; vinpocetine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]
1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; Papaverine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]
CTD PMID:10618442 PMID:10814504 PMID:10872825 NCBI chr10:20,397,052...20,725,078
Ensembl chr10:20,398,004...20,725,078
JBrowse link
G Pde8a phosphodiesterase 8A multiple interactions
increases metabolic processing
increases hydrolysis
ISO
EXP
Dipyridamole inhibits the reaction [PDE8A protein results in increased metabolism of Cyclic AMP]; E 4021 inhibits the reaction [PDE8A protein results in increased metabolism of Cyclic AMP]
PDE8A protein results in increased hydrolysis of Cyclic AMP
Dipyridamole inhibits the reaction [PDE8A protein results in increased hydrolysis of Cyclic AMP]
CTD PMID:9671792 PMID:12681444 NCBI chr 7:81,213,265...81,334,535
Ensembl chr 7:81,213,596...81,334,533
JBrowse link
G Pde8b phosphodiesterase 8B multiple interactions
increases metabolic processing
increases hydrolysis
ISO 9-(2-hydroxy-3-nonyl)adenine inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE8B protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP]; E 4021 inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP]; Sildenafil Citrate inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP] CTD PMID:9784418 PMID:12681444 NCBI chr13:95,024,105...95,250,401
Ensembl chr13:95,024,454...95,250,336
JBrowse link
G Pde9a phosphodiesterase 9A increases hydrolysis ISO PDE9A protein results in increased hydrolysis of Cyclic AMP CTD PMID:9624146 NCBI chr17:31,386,105...31,476,309
Ensembl chr17:31,386,210...31,476,310
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 multiple interactions
affects abundance
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; [PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP]; tubacin affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; tubastatin A affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; W 7 affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 NCBI chr 2:71,873,215...71,903,858
Ensembl chr 2:71,873,224...71,903,858
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 multiple interactions ISO PEBP1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP] CTD PMID:26670611 NCBI chr 5:117,282,651...117,287,564
Ensembl chr 5:117,282,654...117,287,625
JBrowse link
G Pfn2 profilin 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of PFN2 mRNA] CTD PMID:19414516 NCBI chr 3:57,841,895...57,847,757
Ensembl chr 3:57,841,895...57,848,079
JBrowse link
G Pkia protein kinase inhibitor, alpha multiple interactions ISO [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PKIA protein] CTD PMID:29669941 NCBI chr 3:7,366,604...7,445,366
Ensembl chr 3:7,366,669...7,445,366
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) increases expression
multiple interactions
ISO Cyclic AMP results in increased expression of PLA2G4A mRNA; Cyclic AMP results in increased expression of PLA2G4A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of PLA2G4A mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of PLA2G4A protein]
CTD PMID:22187434 NCBI chr 1:149,829,618...149,961,290
Ensembl chr 1:149,829,618...149,961,290
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions
increases abundance
ISO
EXP
[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP; INS1 protein inhibits the reaction [[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP]
POMC protein modified form results in increased abundance of Cyclic AMP
Quercetin analog inhibits the reaction [POMC protein modified form results in increased abundance of Cyclic AMP]
CTD PMID:4306506 PMID:26586997 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Cyclic AMP results in increased expression of POR mRNA CTD PMID:25576683 NCBI chr 5:135,670,040...135,735,326
Ensembl chr 5:135,670,033...135,735,326
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions
increases expression
EXP
ISO
Cyclic AMP promotes the reaction [PPARGC1A protein binds to CYP2A5 promoter]; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in decreased expression of IL15RA mRNA]; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in increased expression of IL1RN mRNA]
[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA; [Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA]; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased phosphorylation of PPARGC1A protein]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased phosphorylation of PPARGC1A protein]
Cyclic AMP results in increased expression of PPARGC1A mRNA
CTD PMID:18602936 PMID:22117073 PMID:22676303 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of PPP1R14B mRNA] CTD PMID:19414516 NCBI chr19:6,975,048...6,977,324
Ensembl chr19:6,974,968...6,977,324
JBrowse link
G Prkacb protein kinase, cAMP dependent, catalytic, beta affects response to substance
multiple interactions
ISO PRKACB protein mutant form affects the susceptibility to Cyclic AMP
[PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PKIA protein]; [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein]
CTD PMID:29669941 NCBI chr 3:146,729,579...146,812,946
Ensembl chr 3:146,729,574...146,812,990
JBrowse link
G Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha multiple interactions ISO [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein] CTD PMID:29669941 NCBI chr11:109,649,023...109,669,663
Ensembl chr11:109,649,405...109,669,656
JBrowse link
G Prkar2a protein kinase, cAMP dependent regulatory, type II alpha multiple interactions ISO Clozapine inhibits the reaction [Cyclic AMP binds to PRKAR2A protein]; Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein] CTD PMID:11907174 NCBI chr 9:108,692,143...108,750,444
Ensembl chr 9:108,689,314...108,750,436
JBrowse link
G Prkar2b protein kinase, cAMP dependent regulatory, type II beta multiple interactions ISO Clozapine inhibits the reaction [Cyclic AMP binds to PRKAR2B protein]; Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein] CTD PMID:11907174 NCBI chr12:31,958,450...32,061,648
Ensembl chr12:31,958,476...32,061,296
JBrowse link
G Prl prolactin multiple interactions
increases secretion
ISO [Atrazine results in increased abundance of Cyclic AMP] which results in increased secretion of PRL protein
2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 4-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]
Cyclic AMP results in increased secretion of PRL protein
CTD PMID:20074812 PMID:23022511 PMID:31953017 PMID:32781018 NCBI chr13:27,057,570...27,065,204
Ensembl chr13:27,057,570...27,065,205
JBrowse link
G Prok1 prokineticin 1 affects response to substance ISO PROK1 protein affects the susceptibility to Cyclic AMP CTD PMID:21546446 NCBI chr 3:107,231,916...107,239,707
Ensembl chr 3:107,232,797...107,239,707
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions EXP [5-hydroxyindomethacin binds to PTGDR2 protein] which results in decreased abundance of Cyclic AMP; [Indomethacin binds to PTGDR2 protein] which results in decreased abundance of Cyclic AMP; [sulindac sulfide binds to PTGDR2 protein] which results in decreased abundance of Cyclic AMP CTD PMID:15563582 NCBI chr19:10,924,519...10,942,511
Ensembl chr19:10,937,160...10,942,511
JBrowse link
G Ptger2 prostaglandin E receptor 2 (subtype EP2) multiple interactions ISO [Dinoprostone results in increased activity of PTGER2 protein] which results in increased chemical synthesis of Cyclic AMP; nickel sulfate promotes the reaction [[Dinoprostone results in increased activity of PTGER2 protein] which results in increased chemical synthesis of Cyclic AMP] CTD PMID:23526216 NCBI chr14:44,988,111...45,003,820
Ensembl chr14:44,988,195...45,003,820
JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) multiple interactions EXP [Dinoprostone results in increased activity of PTGER3 protein] which results in decreased abundance of Cyclic AMP CTD PMID:10357836 NCBI chr 3:157,566,821...157,644,758
Ensembl chr 3:157,566,892...157,645,888
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) multiple interactions ISO [Dinoprostone results in increased activity of PTGER4 protein] which results in increased chemical synthesis of Cyclic AMP; nickel sulfate promotes the reaction [[Dinoprostone results in increased activity of PTGER4 protein] which results in increased chemical synthesis of Cyclic AMP] CTD PMID:23526216 NCBI chr15:5,233,399...5,244,187
Ensembl chr15:5,206,661...5,244,187
JBrowse link
G Ptgir prostaglandin I receptor (IP) multiple interactions ISO [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP; GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP] CTD PMID:11895442 NCBI chr 7:16,906,490...16,910,905
Ensembl chr 7:16,906,490...16,910,905
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP] CTD PMID:21873648 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pth parathyroid hormone increases abundance ISO PTH protein results in increased abundance of Cyclic AMP CTD PMID:26851681 NCBI chr 7:113,385,576...113,388,672
Ensembl chr 7:113,385,580...113,388,570
JBrowse link
G Pthlh parathyroid hormone-like peptide increases abundance ISO PTHLH protein results in increased abundance of Cyclic AMP CTD PMID:10600786 NCBI chr 6:147,252,109...147,264,013
Ensembl chr 6:147,252,101...147,264,183
JBrowse link
G Ptma prothymosin alpha increases abundance EXP PTMA protein results in increased abundance of Cyclic AMP CTD PMID:9147362 NCBI chr 1:86,526,557...86,530,712
Ensembl chr 1:86,526,726...86,530,712
JBrowse link
G Rab3b RAB3B, member RAS oncogene family multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RAB3B mRNA] CTD PMID:19414516 NCBI chr 4:108,879,070...108,943,324
Ensembl chr 4:108,879,063...108,943,324
JBrowse link
G Rap1a RAS-related protein 1a increases activity ISO Cyclic AMP results in increased activity of RAP1A protein CTD PMID:24701590 NCBI chr 3:105,727,260...105,801,394
Ensembl chr 3:105,727,267...105,801,336
JBrowse link
G Rap1b RAS related protein 1b multiple interactions ISO [Pentoxifylline results in increased abundance of Cyclic AMP] results in increased abundance of [RAP1B protein binds to Guanosine Triphosphate] CTD PMID:21693435 NCBI chr10:117,814,597...117,845,974
Ensembl chr10:117,813,871...117,846,035
JBrowse link
G Rbm12 RNA binding motif protein 12 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RBM12 mRNA] CTD PMID:19414516 NCBI chr 2:156,094,882...156,111,965
Ensembl chr 2:156,091,958...156,111,978
JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RGL1 mRNA] CTD PMID:19414516 NCBI chr 1:152,516,762...152,766,308
Ensembl chr 1:152,516,760...152,766,351
JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RMDN3 mRNA] CTD PMID:19414516 NCBI chr 2:119,136,998...119,157,034
Ensembl chr 2:119,137,001...119,157,034
JBrowse link
G Sct secretin multiple interactions
increases abundance
ISO Epinephrine inhibits the reaction [SCT protein results in increased abundance of Cyclic AMP] CTD PMID:6312992 NCBI chr 7:141,278,329...141,279,174
Ensembl chr 7:141,278,330...141,279,133
JBrowse link
G Sdc1 syndecan 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of SDC1 mRNA] CTD PMID:19414516 NCBI chr12:8,771,396...8,793,716
Ensembl chr12:8,771,323...8,793,715
JBrowse link
G Slc22a27 solute carrier family 22, member 27 multiple interactions EXP Cyclic AMP inhibits the reaction [SLC22A27 protein alternative form results in increased uptake of Carnitine] CTD PMID:20332632 NCBI chr19:7,864,388...7,966,517
Ensembl chr19:7,864,388...7,966,027
JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 affects transport ISO SLC22A8 protein affects the transport of Cyclic AMP CTD PMID:11306713 NCBI chr19:8,591,254...8,611,835
Ensembl chr19:8,591,254...8,611,835
JBrowse link
G Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 affects expression
multiple interactions
ISO Cyclic AMP affects the expression of SLC2A5 mRNA
[[Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein] which results in increased uptake of Fructose; [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein
[Fructose results in increased abundance of Cyclic AMP] which results in increased stability of SLC2A5 mRNA
CTD PMID:8037665 PMID:8554516 PMID:12820898 NCBI chr 4:150,119,344...150,144,168
Ensembl chr 4:150,119,283...150,144,169
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 multiple interactions ISO Nitric Oxide inhibits the reaction [SLC4A2 protein promotes the reaction [Cyclic AMP results in increased transport of Bicarbonates]]; SLC4A2 protein promotes the reaction [Cyclic AMP results in increased transport of Bicarbonates] CTD PMID:12612912 NCBI chr 5:24,423,761...24,440,947
Ensembl chr 5:24,423,837...24,440,950
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of SMOC2 mRNA] CTD PMID:19414516 NCBI chr17:14,279,490...14,404,790
Ensembl chr17:14,279,506...14,404,790
JBrowse link
G Snx33 sorting nexin 33 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of SNX33 mRNA] CTD PMID:19414516 NCBI chr 9:56,917,188...56,928,442
Ensembl chr 9:56,917,193...56,928,371
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [[[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein]; [[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein; dorsomorphin inhibits the reaction [[[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein] CTD PMID:23782265 NCBI chr11:117,966,079...117,970,336
Ensembl chr11:117,966,079...117,970,047
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO WNT5A protein affects the reaction [[Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] which results in increased expression of SOD2 mRNA] CTD PMID:20685861 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 increases expression EXP Cyclic AMP results in increased expression of SRD5A1 mRNA CTD PMID:25576683 NCBI chr13:69,573,449...69,611,485
Ensembl chr13:69,573,449...69,611,442
JBrowse link
G Sst somatostatin multiple interactions ISO [SST protein co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22056254 NCBI chr16:23,889,573...23,891,342
Ensembl chr16:23,889,573...23,890,958
JBrowse link
G Sstr2 somatostatin receptor 2 multiple interactions ISO [64Cu-CB-TE2A-Y3-TATE co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [SST protein co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22056254 NCBI chr11:113,619,327...113,626,028
Ensembl chr11:113,619,342...113,626,028
JBrowse link
G St6gal2 beta galactoside alpha 2,6 sialyltransferase 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ST6GAL2 mRNA] CTD PMID:19414516 NCBI chr17:55,445,118...55,514,581
Ensembl chr17:55,445,382...55,514,581
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
increases expression
EXP [Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein; Calcium inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]; Diltiazem promotes the reaction [Cyclic AMP results in increased expression of STAR protein]; Isradipine promotes the reaction [Cyclic AMP results in increased expression of STAR protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]]; myricetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; Nifedipine promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]; quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Verapamil promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Verapamil promotes the reaction [Cyclic AMP results in increased expression of STAR protein]
Cyclic AMP results in increased expression of STAR mRNA; Cyclic AMP results in increased expression of STAR protein
CTD PMID:19822634 PMID:20100736 PMID:25576683 PMID:28668616 NCBI chr 8:25,808,474...25,815,982
Ensembl chr 8:25,806,555...25,815,982
JBrowse link
G Taar1 trace amine-associated receptor 1 multiple interactions ISO
EXP
[Octopamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [phenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [tryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP
[3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [3-methoxytyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [3-tyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [4-chloro-2-(imidazolin-2-yl)isoindoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [4-phenyl-1,2,3,4-tetrahydroisoquinoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [5-Methoxytryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [6-nitroquipazine analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Antazoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [BE 2254 results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [cirazoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Clonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [efaroxan results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Fenoldopam results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Guanabenz results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [harman results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Histamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Idazoxan results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Methoxydimethyltryptamines results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [moxonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [N-methylquipazine analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [O-methyltyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Octopamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [phenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Quipazine analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [rilmenidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tranylcypromine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [tryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tryptamines analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP
CTD PMID:19725810 NCBI chr10:23,920,406...23,921,404
Ensembl chr10:23,920,356...23,921,469
JBrowse link
G Tas1r2 taste receptor, type 1, member 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TAS1R2 mRNA] CTD PMID:19414516 NCBI chr 4:139,653,538...139,670,280
Ensembl chr 4:139,653,538...139,670,280
JBrowse link
G Tas2r105 taste receptor, type 2, member 105 multiple interactions EXP Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in decreased abundance of Cyclic AMP]]; TAS2R105 protein affects the reaction [Cycloheximide results in decreased abundance of Cyclic AMP] CTD PMID:15087236 NCBI chr 6:131,686,561...131,687,463
Ensembl chr 6:131,686,532...131,687,495
JBrowse link
G Tax1bp1 Tax1 (human T cell leukemia virus type I) binding protein 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TAX1BP1 mRNA] CTD PMID:19414516 NCBI chr 6:52,713,692...52,766,780
Ensembl chr 6:52,713,729...52,766,780
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA CTD PMID:32781018 NCBI chr 3:81,958,412...81,975,728
Ensembl chr 3:81,957,090...81,976,202
JBrowse link
G Tex14 testis expressed gene 14 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TEX14 mRNA] CTD PMID:19414516 NCBI chr11:87,405,013...87,555,823
Ensembl chr11:87,405,065...87,555,823
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO CARM1 protein promotes the reaction [Cyclic AMP results in increased expression of TFF1 mRNA]; Cyclic AMP promotes the reaction [CARM1 protein binds to TFF1 promoter] CTD PMID:20360387 NCBI chr17:31,161,395...31,165,060
Ensembl chr17:31,161,395...31,165,277
JBrowse link
G Tmsb15b2 thymosin beta 15b2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TMSB15B2 mRNA] CTD PMID:19414516 NCBI chr  X:136,954,988...136,957,979
Ensembl chr  X:136,955,265...136,975,497
JBrowse link
G Tmtc4 transmembrane and tetratricopeptide repeat containing 4 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TMTC4 mRNA] CTD PMID:19414516 NCBI chr14:122,918,971...122,983,285
Ensembl chr14:122,918,971...122,984,035
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO
EXP
Cyclic AMP results in decreased expression of TNF protein
Cyclic AMP inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[[S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:8550079 PMID:21266552 PMID:23566200 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 decreases expression EXP Cyclic AMP results in decreased expression of TNFSF12 mRNA CTD PMID:22117073 NCBI chr11:69,686,240...69,696,098
Ensembl chr11:69,686,250...69,695,849
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression
multiple interactions
ISO Cyclic AMP results in increased expression of TRPV4 mRNA; Cyclic AMP results in increased expression of TRPV4 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of TRPV4 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of TRPV4 protein]
CTD PMID:22187434 NCBI chr 5:114,622,152...114,658,435
Ensembl chr 5:114,622,152...114,658,421
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions
increases abundance
ISO [Cobalt binds to dipyrido(3,2-a-2',3'-c)phenazine binds to N-(2-hydroxybenzyl)glycine analog] inhibits the reaction [TSHB protein results in increased abundance of Cyclic AMP]; [TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP; bisphenol A inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Diethylstilbestrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; resveratrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; TSHB protein inhibits the reaction [NCGC 00229600 inhibits the reaction [TSHR protein results in increased abundance of Cyclic AMP]] CTD PMID:19766106 PMID:21072367 PMID:21123444 NCBI chr 3:102,777,398...102,789,082
Ensembl chr 3:102,775,465...102,782,718
JBrowse link
G Tshr thyroid stimulating hormone receptor multiple interactions
increases abundance
ISO [TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP; bisphenol A inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Diethylstilbestrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; NCGC 00229600 inhibits the reaction [TSHR protein results in increased abundance of Cyclic AMP]; resveratrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; TSHB protein inhibits the reaction [NCGC 00229600 inhibits the reaction [TSHR protein results in increased abundance of Cyclic AMP]] CTD PMID:19766106 PMID:21123444 NCBI chr12:91,400,993...91,540,509
Ensembl chr12:91,384,563...91,549,808
JBrowse link
G Ttc6 tetratricopeptide repeat domain 6 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TTC6 mRNA] CTD PMID:19414516 NCBI chr12:57,546,704...57,737,911
Ensembl chr12:57,564,113...57,737,928
JBrowse link
G Uba5 ubiquitin-like modifier activating enzyme 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of UBA5 mRNA] CTD PMID:19414516 NCBI chr 9:104,046,587...104,063,176
Ensembl chr 9:104,046,599...104,063,134
JBrowse link
G Vash1 vasohibin 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VASH1 mRNA] CTD PMID:19414516 NCBI chr12:86,678,700...86,695,688
Ensembl chr12:86,678,700...86,692,091
JBrowse link
G Vash2 vasohibin 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VASH2 mRNA] CTD PMID:19414516 NCBI chr 1:190,947,646...190,979,368
Ensembl chr 1:190,947,646...190,979,296
JBrowse link
G Vat1 vesicle amine transport 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VAT1 mRNA] CTD PMID:19414516 NCBI chr11:101,458,748...101,466,199
Ensembl chr11:101,458,745...101,466,230
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Cyclic AMP affects the reaction [Norepinephrine results in increased expression of VEGFA mRNA] CTD PMID:10788502 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vip vasoactive intestinal polypeptide multiple interactions
increases abundance
ISO [VIP protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP
alpha-hexachlorocyclohexane inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]; Endrin inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]; Hexachlorocyclohexane inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]
VIP protein results in increased abundance of Cyclic AMP; VIP results in increased abundance of Cyclic AMP
CTD PMID:1657658 PMID:2467674 PMID:7733904 PMID:20732086 NCBI chr10:5,639,193...5,647,617
Ensembl chr10:5,639,218...5,647,617
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 multiple interactions ISO [ADCYAP1 protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP; [VIP protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:7733904 NCBI chr12:116,077,420...116,148,637
Ensembl chr12:116,077,726...116,146,261
JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A multiple interactions ISO WNT5A protein affects the reaction [[Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] which results in increased expression of SOD2 mRNA]; WNT5A protein affects the reaction [Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] CTD PMID:20685861 NCBI chr14:28,504,543...28,527,448
Ensembl chr14:28,504,750...28,527,448
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 increases abundance EXP ZFP36L2 protein mutant form results in increased abundance of Cyclic AMP CTD PMID:24830504 NCBI chr17:84,183,924...84,187,947
Ensembl chr17:84,183,931...84,187,947
JBrowse link
3',5'-cyclic GMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 increases export
increases transport
multiple interactions
ISO ABCC4 protein results in increased export of Cyclic GMP
ABCC4 protein results in increased transport of Cyclic GMP
daidzein inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; Dipyridamole inhibits the reaction [ABCC4 protein results in increased transport of Cyclic GMP]; hesperetin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; naringenin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; Probenecid inhibits the reaction [ABCC4 protein results in increased transport of Cyclic GMP]; Quercetin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; resveratrol inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; Silymarin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]
CTD PMID:11856762 PMID:16156793 NCBI chr14:118,482,692...118,707,856
Ensembl chr14:118,482,692...118,706,219
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) multiple interactions
increases abundance
ISO AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]
AGT protein modified form results in increased abundance of Cyclic GMP
CTD PMID:11696475 PMID:28299329 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [PD 123319 results in decreased activity of AGTR2 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP] CTD PMID:16982965 NCBI chr  X:21,484,624...21,488,833
Ensembl chr  X:21,484,544...21,489,164
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Cyclic GMP] CTD PMID:12891555 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial multiple interactions ISO ALDH2 protein affects the reaction [Nitroglycerin results in decreased abundance of Cyclic GMP] CTD PMID:17585900 NCBI chr 5:121,566,027...121,593,824
Ensembl chr 5:121,566,027...121,593,824
JBrowse link
G Apoe apolipoprotein E decreases abundance EXP APOE gene mutant form results in decreased abundance of Cyclic GMP CTD PMID:11397713 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 multiple interactions ISO [bradykinin, Leu(8)-des-Arg(9)- results in decreased activity of BDKRB1 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP] CTD PMID:16982965 NCBI chr12:105,604,091...105,605,511
Ensembl chr12:105,603,085...105,605,428
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions ISO [icatibant results in decreased activity of BDKRB2 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP] CTD PMID:16982965 NCBI chr12:105,563,172...105,595,244
Ensembl chr12:105,563,226...105,595,237
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Cyclic GMP affects the reaction [Nitric Oxide results in decreased activity of CASP3 protein] CTD PMID:9388267 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP] CTD PMID:25490417 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cct7 chaperonin containing Tcp1, subunit 7 (eta) multiple interactions ISO CCT7 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased abundance of Cyclic GMP] CTD PMID:24213632 NCBI chr 6:85,451,505...85,468,477
Ensembl chr 6:85,451,514...85,468,475
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases abundance
ISO Puromycin Aminonucleoside inhibits the reaction [EDN1 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Edn3 endothelin 3 multiple interactions
increases abundance
ISO Puromycin Aminonucleoside promotes the reaction [EDN3 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr 2:174,760,619...174,784,042
Ensembl chr 2:174,760,619...174,784,042
JBrowse link
G Epo erythropoietin multiple interactions EXP EPO protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP]; EPO protein inhibits the reaction [HPH1 gene mutant form results in decreased abundance of Cyclic GMP] CTD PMID:25041251 PMID:25490417 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G Gch1 GTP cyclohydrolase 1 affects abundance
increases abundance
multiple interactions
EXP GCH1 protein affects the abundance of Cyclic GMP
GCH1 gene mutant form results in increased abundance of Cyclic GMP
CAT protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP]; EPO protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP]
CTD PMID:21963838 PMID:25490417 NCBI chr14:47,153,895...47,189,413
Ensembl chr14:47,153,895...47,189,413
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO [manganese chloride results in increased chemical synthesis of Cyclic GMP] which results in increased secretion of GNRH1 protein CTD PMID:17110411 PMID:17290048 NCBI chr14:67,745,181...67,749,440
Ensembl chr14:67,745,181...67,749,439
JBrowse link
G Gucy1a1 guanylate cyclase 1, soluble, alpha 1 multiple interactions
increases abundance
ISO [GUCY1A1 protein binds to GUCY1B1 protein] which results in increased chemical synthesis of Cyclic GMP; GUCY1A1 protein mutant form inhibits the reaction [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased abundance of Cyclic GMP]; GUCY1A1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased abundance of Cyclic GMP]
GUCY1A1 gene mutant form results in increased abundance of Cyclic GMP
CTD PMID:22171090 PMID:24213632 PMID:25373139 NCBI chr 3:82,092,427...82,145,946
Ensembl chr 3:82,092,427...82,145,789
JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 multiple interactions ISO [GUCY1A1 protein binds to GUCY1B1 protein] which results in increased chemical synthesis of Cyclic GMP CTD PMID:22171090 NCBI chr 3:82,032,004...82,074,711
Ensembl chr 3:82,032,006...82,074,689
JBrowse link
G Hmox2 heme oxygenase 2 affects abundance EXP HMOX2 affects the abundance of Cyclic GMP CTD PMID:16181104 NCBI chr16:4,726,361...4,766,742
Ensembl chr16:4,726,361...4,766,742
JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 increases expression EXP Cyclic GMP results in increased expression of IL12RB2 mRNA CTD PMID:12451176 NCBI chr 6:67,285,986...67,376,293
Ensembl chr 6:67,291,318...67,376,188
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases abundance
ISO Halothane inhibits the reaction [IL1B protein results in increased abundance of Cyclic GMP]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Cyclic GMP; nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Cyclic GMP]
CTD PMID:11506125 PMID:14762100 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions
decreases phosphorylation
ISO Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K1 protein]
Cyclic GMP results in decreased phosphorylation of MAP2K1 protein
CTD PMID:18225537 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 decreases phosphorylation
multiple interactions
ISO Cyclic GMP results in decreased phosphorylation of MAP2K2 protein
Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein]
CTD PMID:18225537 NCBI chr10:81,105,913...81,124,697
Ensembl chr10:81,105,915...81,133,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO Cyclic GMP analog results in increased activity of MAPK8 protein CTD PMID:11051267 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO [testosterone enanthate results in increased expression of NOS2 mRNA] which results in increased abundance of Cyclic GMP CTD PMID:20463352 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions
increases abundance
EXP
ISO
NOS3 protein affects the reaction [Ramipril results in increased abundance of Cyclic GMP]
NOS3 protein results in increased abundance of Cyclic GMP
CTD PMID:11504159 PMID:16891913 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Nppa natriuretic peptide type A multiple interactions
increases abundance
ISO
EXP
Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K1 protein]; Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein]
NPPA protein results in increased abundance of Cyclic GMP
AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]; carvedilol promotes the reaction [NPPA protein results in increased abundance of Cyclic GMP]; Puromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]; vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]
CTD PMID:9421401 PMID:11696475 PMID:12022755 PMID:12582005 PMID:12972712 PMID:18225537 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079
JBrowse link
G Nppc natriuretic peptide type C increases chemical synthesis
increases abundance
multiple interactions
ISO NPPC protein results in increased chemical synthesis of Cyclic GMP
NPPC protein results in increased abundance of Cyclic GMP
Ammonia inhibits the reaction [NPPC protein results in increased chemical synthesis of Cyclic GMP]; Fluoroacetates inhibits the reaction [NPPC protein results in increased abundance of Cyclic GMP]
CTD PMID:17629948 PMID:18222015 NCBI chr 1:86,666,293...86,670,573
Ensembl chr 1:86,666,291...86,670,571
JBrowse link
G Pde10a phosphodiesterase 10A multiple interactions
increases hydrolysis
ISO Cyclic AMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP]; Cyclic GMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP] CTD PMID:10373451 NCBI chr17:8,525,187...8,986,648
Ensembl chr17:8,525,372...8,986,648
JBrowse link
G Pde11a phosphodiesterase 11A multiple interactions
increases hydrolysis
ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]; Dipyridamole inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]; zaprinast inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP] CTD PMID:10725373 NCBI chr 2:75,985,808...76,339,145
Ensembl chr 2:75,989,141...76,338,774
JBrowse link
G Pde1a phosphodiesterase 1A, calmodulin-dependent multiple interactions ISO PDE1A protein inhibits the reaction [Nitroglycerin results in increased abundance of Cyclic GMP] CTD PMID:11696475 NCBI chr 2:79,834,453...80,196,522
Ensembl chr 2:79,834,453...80,129,458
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific decreases abundance ISO PDE5A protein results in decreased abundance of Cyclic GMP CTD PMID:10422958 NCBI chr 3:122,729,158...122,859,374
Ensembl chr 3:122,728,947...122,859,374
JBrowse link
G Pde9a phosphodiesterase 9A increases hydrolysis
multiple interactions
ISO PDE9A protein results in increased hydrolysis of Cyclic GMP
zaprinast inhibits the reaction [PDE9A protein results in increased hydrolysis of Cyclic GMP]
CTD PMID:9624146 NCBI chr17:31,386,105...31,476,309
Ensembl chr17:31,386,210...31,476,310
JBrowse link
G Pomc pro-opiomelanocortin-alpha affects abundance ISO POMC protein affects the abundance of Cyclic GMP CTD PMID:11193135 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 increases activity ISO Cyclic GMP results in increased activity of PTPN12 protein CTD PMID:12714323 NCBI chr 5:20,986,645...21,055,911
Ensembl chr 5:20,986,645...21,055,911
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO STK11 protein promotes the reaction [Histamine results in increased abundance of Cyclic GMP] CTD PMID:21145922 NCBI chr10:80,115,767...80,130,679
Ensembl chr10:80,115,803...80,130,682
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases abundance
ISO 7-(2-(4-(4-nitrobenzene)piperazinyl)ethyl)-1,3-dimethylxanthine inhibits the reaction [TNF protein results in decreased abundance of Cyclic GMP]; KMUP 1 inhibits the reaction [TNF protein results in decreased abundance of Cyclic GMP]; zaprinast inhibits the reaction [TNF protein results in decreased abundance of Cyclic GMP] CTD PMID:16754782 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases abundance
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [VEGFA protein results in increased abundance of Cyclic GMP] CTD PMID:18575783 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vim vimentin multiple interactions EXP VIM protein affects the susceptibility to [Acetylcholine co-treated with Cyclic GMP co-treated with Indomethacin] CTD PMID:11588525 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO [Xanthine co-treated with XDH protein] inhibits the reaction [Nitroprusside results in increased abundance of Cyclic GMP] CTD PMID:17339839 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
3'-CMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) multiple interactions EXP [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate CTD PMID:2579070 NCBI chr 7:126,976,458...126,980,499
Ensembl chr 7:126,975,914...126,980,501
JBrowse link
3'-phospho-5'-adenylyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 8:67,494,875...67,502,644
Ensembl chr 8:67,494,858...67,502,584
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G P2ry1 purinergic receptor P2Y, G-protein coupled 1 decreases activity ISO Phosphoadenosine Phosphosulfate results in decreased activity of P2RY1 protein CTD PMID:22273509 NCBI chr 3:61,002,785...61,008,982
Ensembl chr 3:61,002,795...61,008,982
JBrowse link
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 7:126,672,865...126,690,443
Ensembl chr 7:126,672,865...126,676,432
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions ISO [Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol; Celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol]; SULT2A1 protein affects the metabolism of [Phosphoadenosine Phosphosulfate co-treated with Ethinyl Estradiol] CTD PMID:15483193 NCBI chr 7:13,796,246...13,837,410
Ensembl chr 7:13,796,246...13,837,409
JBrowse link
7-methyl-7,8-dihydroguanosine-5'-diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4e eukaryotic translation initiation factor 4E multiple interactions
affects binding
ISO 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine-5'-monophosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Quinolones inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Sulfonamides inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] CTD PMID:27592390 NCBI chr 3:138,526,191...138,559,696
Ensembl chr 3:138,526,179...138,559,696
JBrowse link
7-methyl-GTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine triphosphate inhibits the reaction [RNA Caps binds to EIF4E protein] CTD PMID:27592390 NCBI chr 3:138,526,191...138,559,696
Ensembl chr 3:138,526,179...138,559,696
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
affects binding
ISO 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate]; Sirolimus promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate] CTD PMID:25940091 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 multiple interactions
affects binding
ISO 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [EIF4G1 protein binds to 7-methylguanosine triphosphate]; Sirolimus inhibits the reaction [EIF4G1 protein binds to 7-methylguanosine triphosphate] CTD PMID:25940091 NCBI chr16:20,672,720...20,692,883
Ensembl chr16:20,668,313...20,692,884
JBrowse link
8-(4-chlorophenylthio)-cAMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 multiple interactions
increases expression
EXP Mevalonic Acid inhibits the reaction [mevastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein]]; pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein] CTD PMID:16415093 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCB11 mRNA CTD PMID:27160211 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCB1A mRNA CTD PMID:27160211 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCC2 mRNA CTD PMID:27160211 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCG2 mRNA CTD PMID:27160211 NCBI chr 6:58,584,491...58,692,451
Ensembl chr 6:58,584,523...58,695,676
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased phosphorylation of AKT1 protein CTD PMID:20610540 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) increases expression
increases response to substance
EXP
ISO
8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 mRNA; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 protein
BCL2L11 protein results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP
CTD PMID:14996839 NCBI chr 2:128,126,038...128,162,547
Ensembl chr 2:128,126,038...128,162,547
JBrowse link
G Casp3 caspase 3 increases activity EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased activity of CASP3 protein CTD PMID:14996839 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cfl1 cofilin 1, non-muscle decreases phosphorylation ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in decreased phosphorylation of CFL1 protein CTD PMID:20610540 NCBI chr19:5,490,455...5,494,031
Ensembl chr19:5,490,455...5,495,201
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form; [5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form CTD PMID:15163550 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased phosphorylation of and results in increased activity of CREB1 protein
8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased phosphorylation of CREB1 protein
CTD PMID:14741741 PMID:20610540 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NFE2L2 mRNA CTD PMID:27160211 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions EXP NR1H2 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased export of Cholesterol]] CTD PMID:16415093 NCBI chr 7:44,549,616...44,553,968
Ensembl chr 7:44,549,616...44,553,951
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions EXP NR1H3 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased export of Cholesterol]] CTD PMID:16415093 NCBI chr 2:91,184,061...91,202,829
Ensembl chr 2:91,184,061...91,202,834
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NR1I2 mRNA CTD PMID:27160211 NCBI chr16:38,248,349...38,294,849
Ensembl chr16:38,248,323...38,294,824
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NR1I3 mRNA CTD PMID:27160211 NCBI chr 1:171,213,934...171,218,845
Ensembl chr 1:171,213,970...171,220,701
JBrowse link
G Rhoa ras homolog family member A multiple interactions
decreases activity
ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP inhibits the reaction [RHOA protein binds to RTKN protein]
8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in decreased activity of RHOA protein
CTD PMID:20610540 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Rtkn rhotekin multiple interactions ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP inhibits the reaction [RHOA protein binds to RTKN protein] CTD PMID:20610540 NCBI chr 6:83,135,505...83,152,579
Ensembl chr 6:83,135,463...83,152,579
JBrowse link
G Scnn1a sodium channel, nonvoltage-gated 1 alpha multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:15161604 NCBI chr 6:125,314,271...125,344,943
Ensembl chr 6:125,320,659...125,344,943
JBrowse link
G Scnn1b sodium channel, nonvoltage-gated 1 beta multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:15161604 NCBI chr 7:121,865,038...121,918,728
Ensembl chr 7:121,865,038...121,918,514
JBrowse link
G Scnn1g sodium channel, nonvoltage-gated 1 gamma multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:15161604 NCBI chr 7:121,734,420...121,768,482
Ensembl chr 7:121,734,479...121,768,475
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of SLC10A1 mRNA CTD PMID:27160211 NCBI chr12:80,953,185...80,968,705
Ensembl chr12:80,953,183...80,968,705
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of SLCO1A1 mRNA CTD PMID:27160211 NCBI chr 6:141,907,281...141,946,962
Ensembl chr 6:141,907,282...141,946,962
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of SLCO1A4 mRNA CTD PMID:27160211 NCBI chr 6:141,805,438...141,856,284
Ensembl chr 6:141,805,440...141,856,199
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of SLCO1B2 mRNA CTD PMID:27160211 NCBI chr 6:141,629,452...141,686,646
Ensembl chr 6:141,629,518...141,686,646
JBrowse link
G Snap25 synaptosomal-associated protein 25 multiple interactions
affects splicing
ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP affects the splicing of SNAP25 exon] CTD PMID:22684629 NCBI chr 2:136,713,439...136,782,428
Ensembl chr 2:136,713,453...136,782,428
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1] CTD PMID:12886029 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242
JBrowse link
G Vip vasoactive intestinal polypeptide increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of VIP mRNA CTD PMID:2156696 NCBI chr10:5,639,193...5,647,617
Ensembl chr10:5,639,218...5,647,617
JBrowse link
8-(4-chlorophenylthio)-cGMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of ALOX15 mRNA; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of ALOX15 protein CTD PMID:16166323 NCBI chr11:70,344,147...70,390,538
Ensembl chr11:70,344,152...70,352,031
JBrowse link
G Arhgef17 Rho guanine nucleotide exchange factor (GEF) 17 multiple interactions ISO 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] promotes the reaction [ARHGEF17 protein results in increased activity of RHOA protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein; [calyculin A co-treated with Okadaic Acid] inhibits the reaction [2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]]; KT 5823 inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]]; Y 27632 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein] CTD PMID:23195829 NCBI chr 7:100,869,746...100,932,161
Ensembl chr 7:100,869,752...100,932,107
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta increases expression
multiple interactions
EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of CEBPB protein
8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of CEBPB protein]
CTD PMID:20471953 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression
multiple interactions
EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of FABP4 protein
8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of FABP4 protein]
CTD PMID:20471953 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Nppa natriuretic peptide type A multiple interactions ISO [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:11799084 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression
EXP 8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of PPARG protein] CTD PMID:20471953 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I multiple interactions
increases activity
decreases expression
ISO 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] promotes the reaction [ARHGEF17 protein results in increased activity of RHOA protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein; [calyculin A co-treated with Okadaic Acid] inhibits the reaction [2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]]; KT 5823 inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]]; KT 5823 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein]; Y 27632 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]
[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of PRKG1 protein
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in decreased expression of PRKG1 protein; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in decreased expression of PRKG1 protein alternative form
CTD PMID:9366573 PMID:11799084 PMID:23195829 NCBI chr19:30,564,487...31,765,268
Ensembl chr19:30,564,489...31,765,033
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] promotes the reaction [ARHGEF17 protein results in increased activity of RHOA protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein; KT 5823 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein] CTD PMID:23195829 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Scnn1a sodium channel, nonvoltage-gated 1 alpha multiple interactions ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr 6:125,314,271...125,344,943
Ensembl chr 6:125,320,659...125,344,943
JBrowse link
G Scnn1b sodium channel, nonvoltage-gated 1 beta multiple interactions ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr 7:121,865,038...121,918,728
Ensembl chr 7:121,865,038...121,918,514
JBrowse link
G Scnn1g sodium channel, nonvoltage-gated 1 gamma multiple interactions ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr 7:121,734,420...121,768,482
Ensembl chr 7:121,734,479...121,768,475
JBrowse link
G Srf serum response factor multiple interactions ISO [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein CTD PMID:23195829 NCBI chr17:46,546,838...46,558,267
Ensembl chr17:46,548,329...46,556,175
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation
decreases phosphorylation
ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased phosphorylation of VASP protein
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in decreased phosphorylation of VASP protein
CTD PMID:11799084 PMID:16166323 NCBI chr 7:19,256,929...19,271,854
Ensembl chr 7:19,256,929...19,271,817
JBrowse link
8-Br-cAMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ABCA1 protein CTD PMID:17478430 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA] CTD PMID:27743861 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABCC1 mRNA CTD PMID:22079614 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737
JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA] CTD PMID:27743861 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Abcd2 ATP-binding cassette, sub-family D (ALD), member 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABCD2 mRNA CTD PMID:22079614 NCBI chr15:91,145,871...91,192,007
Ensembl chr15:91,145,871...91,191,799
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABCG1 mRNA CTD PMID:22079614 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA] CTD PMID:30610963 NCBI chr 6:58,584,491...58,692,451
Ensembl chr 6:58,584,523...58,695,676
JBrowse link
G Ablim1 actin-binding LIM protein 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABLIM1 mRNA CTD PMID:22079614 NCBI chr19:57,032,733...57,315,344
Ensembl chr19:57,032,733...57,314,919
JBrowse link
G Ablim2 actin-binding LIM protein 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ABLIM2 mRNA CTD PMID:22079614 NCBI chr 5:35,757,855...35,884,979
Ensembl chr 5:35,757,880...35,884,973
JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ACAT2 mRNA CTD PMID:22079614 NCBI chr17:12,943,042...12,960,725
Ensembl chr17:12,942,890...12,960,747
JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ACE2 mRNA CTD PMID:22079614 NCBI chr  X:164,139,342...164,188,418
Ensembl chr  X:164,139,332...164,188,420
JBrowse link
G Acpp acid phosphatase, prostate decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ACP3 mRNA CTD PMID:22079614 NCBI chr 9:104,288,240...104,337,722
Ensembl chr 9:104,288,251...104,337,748
JBrowse link
G Adamts6 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ADAMTS6 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr13:104,286,518...104,496,695
Ensembl chr13:104,287,835...104,496,695
JBrowse link
G Adamts8 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADAMTS8 mRNA CTD PMID:22079614 NCBI chr 9:30,942,562...30,963,838
Ensembl chr 9:30,942,562...30,963,838
JBrowse link
G Adcy7 adenylate cyclase 7 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADCY7 mRNA CTD PMID:22079614 NCBI chr 8:88,272,190...88,329,965
Ensembl chr 8:88,272,403...88,329,962
JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ADGRD1 mRNA CTD PMID:22079614 NCBI chr 5:129,096,750...129,204,599
Ensembl chr 5:129,096,750...129,204,599
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADGRF5 mRNA CTD PMID:16997883 NCBI chr17:43,360,329...43,459,557
Ensembl chr17:43,360,451...43,459,557
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ADGRG1 mRNA CTD PMID:22079614 NCBI chr 8:94,974,756...95,014,208
Ensembl chr 8:94,974,751...95,014,217
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADGRG2 mRNA CTD PMID:22079614 NCBI chr  X:160,390,318...160,498,076
Ensembl chr  X:160,390,690...160,498,070
JBrowse link
G Adra2a adrenergic receptor, alpha 2a decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADRA2A mRNA CTD PMID:22079614 NCBI chr19:54,045,259...54,048,982
Ensembl chr19:54,044,151...54,048,982
JBrowse link
G Agr2 anterior gradient 2 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of AGR2 mRNA CTD PMID:16997883 NCBI chr12:35,992,925...36,004,081
Ensembl chr12:35,992,907...36,004,087
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AGT mRNA CTD PMID:22079614 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AGTR1 mRNA CTD PMID:22079614 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Ahr aryl-hydrocarbon receptor increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AHR mRNA CTD PMID:22079614 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AIFM1 mRNA CTD PMID:22079614 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563
JBrowse link
G Akap7 A kinase (PRKA) anchor protein 7 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of AKAP7 mRNA CTD PMID:16997883 NCBI chr10:25,169,090...25,299,217
Ensembl chr10:25,169,090...25,307,870
JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AKAP9 mRNA CTD PMID:22079614 NCBI chr 5:3,927,736...4,080,204
Ensembl chr 5:3,928,054...4,081,310
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AKT1 mRNA CTD PMID:22079614 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Alb albumin decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ALB mRNA CTD PMID:22079614 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ALDH1A1 mRNA CTD PMID:22079614 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Angpt1 angiopoietin 1 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ANGPT1 mRNA CTD PMID:16997883 NCBI chr15:42,424,667...42,676,977
Ensembl chr15:42,424,723...42,676,977
JBrowse link
G Angptl1 angiopoietin-like 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ANGPTL1 mRNA CTD PMID:22079614 NCBI chr 1:156,839,023...156,861,078
Ensembl chr 1:156,838,562...156,861,078
JBrowse link
G Ank progressive ankylosis increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ANKH mRNA CTD PMID:20147733 NCBI chr15:27,466,677...27,594,909
Ensembl chr15:27,466,677...27,594,909
JBrowse link
G Anxa8 annexin A8 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of ANXA8 mRNA CTD PMID:16997883 NCBI chr14:34,085,979...34,100,571
Ensembl chr14:34,085,981...34,100,571
JBrowse link
G Aopep aminopeptidase O decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AOPEP mRNA CTD PMID:22079614 NCBI chr13:62,964,893...63,326,096
Ensembl chr13:62,964,893...63,326,096
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APAF1 mRNA CTD PMID:22079614 NCBI chr10:90,989,311...91,082,743
Ensembl chr10:90,989,311...91,082,770
JBrowse link
G Apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of APBB1IP mRNA CTD PMID:22079614 NCBI chr 2:22,755,971...22,875,653
Ensembl chr 2:22,774,094...22,875,653
JBrowse link
G Apc APC, WNT signaling pathway regulator decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APC mRNA CTD PMID:22079614 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Apcdd1 adenomatosis polyposis coli down-regulated 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APCDD1 mRNA CTD PMID:22079614 NCBI chr18:62,922,327...62,953,815
Ensembl chr18:62,922,231...62,961,179
JBrowse link
G Ar androgen receptor decreases expression
multiple interactions
ISO
EXP
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AR mRNA
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of AR mRNA; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of AR mRNA]
CTD PMID:18467523 PMID:22079614 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Areg amphiregulin increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AREG mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 5:91,139,599...91,148,432
Ensembl chr 5:91,139,599...91,148,432
JBrowse link
G Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ARHGEF2 mRNA CTD PMID:22079614 NCBI chr 3:88,593,105...88,649,532
Ensembl chr 3:88,605,966...88,648,052
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor (GEF) 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ARHGEF4 mRNA CTD PMID:22079614 NCBI chr 1:34,677,949...34,812,754
Ensembl chr 1:34,678,188...34,813,309
Ensembl chr 1:34,678,188...34,813,309
JBrowse link
G Arid5b AT rich interactive domain 5B (MRF1-like) decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ARID5B mRNA CTD PMID:22079614 NCBI chr10:68,092,523...68,279,355
Ensembl chr10:68,092,520...68,278,740
JBrowse link
G Armcx3 armadillo repeat containing, X-linked 3 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ARMCX3 mRNA CTD PMID:22079614 NCBI chr  X:134,756,552...134,761,457
Ensembl chr  X:134,756,595...134,761,455
JBrowse link
G Armcx4 armadillo repeat containing, X-linked 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ARMCX4 mRNA CTD PMID:22079614 NCBI chr  X:134,685,650...134,697,775
Ensembl chr  X:134,686,519...134,696,757
JBrowse link
G Asns asparagine synthetase increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ASNS mRNA CTD PMID:22079614 NCBI chr 6:7,675,165...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ATP4A mRNA CTD PMID:22079614 NCBI chr 7:30,712,209...30,725,534
Ensembl chr 7:30,712,209...30,725,534
JBrowse link
G Avpi1 arginine vasopressin-induced 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AVPI1 mRNA CTD PMID:22079614 NCBI chr19:42,123,275...42,128,993
Ensembl chr19:42,123,273...42,129,059
JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of B4GALNT3 mRNA CTD PMID:22079614 NCBI chr 6:120,200,753...120,294,917
Ensembl chr 6:120,203,073...120,294,559
JBrowse link
G Bank1 B cell scaffold protein with ankyrin repeats 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BANK1 mRNA CTD PMID:22079614 NCBI chr 3:136,053,363...136,326,141
Ensembl chr 3:136,053,363...136,326,066
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BAX
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BAX protein
CTD PMID:11802967 PMID:16709600 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcat1 branched chain aminotransferase 1, cytosolic increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BCAT1 mRNA CTD PMID:22079614 NCBI chr 6:144,993,835...145,076,157
Ensembl chr 6:144,993,835...145,076,184
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BCL2 CTD PMID:11802967 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BCL2L11 protein CTD PMID:16709600 NCBI chr 2:128,126,038...128,162,547
Ensembl chr 2:128,126,038...128,162,547
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BDKRB1 mRNA CTD PMID:20147733 NCBI chr12:105,604,091...105,605,511
Ensembl chr12:105,603,085...105,605,428
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BDKRB2 mRNA CTD PMID:20147733 NCBI chr12:105,563,172...105,595,244
Ensembl chr12:105,563,226...105,595,237
JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BMP4 mRNA CTD PMID:22079614 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression
increases expression
ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BMP6 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BMP6 mRNA
CTD PMID:20147733 PMID:22079614 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Brinp1 bone morphogenic protein/retinoic acid inducible neural specific 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BRINP1 mRNA CTD PMID:20147733 NCBI chr 4:68,761,372...68,954,397
Ensembl chr 4:68,761,514...68,954,397
JBrowse link
G Btbd9 BTB (POZ) domain containing 9 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BTBD9 mRNA CTD PMID:22079614 NCBI chr17:30,215,524...30,582,621
Ensembl chr17:30,215,524...30,576,488
JBrowse link
G Cables1 CDK5 and Abl enzyme substrate 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CABLES1 mRNA CTD PMID:22079614 NCBI chr18:11,839,274...11,945,627
Ensembl chr18:11,839,220...11,945,630
JBrowse link
G Cabp7 calcium binding protein 7 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CABP7 mRNA CTD PMID:22079614 NCBI chr11:4,736,892...4,747,179
Ensembl chr11:4,736,892...4,746,778
JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CADM1 mRNA CTD PMID:22079614 NCBI chr 9:47,530,170...47,862,280
Ensembl chr 9:47,530,173...47,857,637
Ensembl chr 9:47,530,173...47,857,637
JBrowse link
G Cadm2 cell adhesion molecule 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CADM2 mRNA CTD PMID:22079614 NCBI chr16:66,655,416...67,620,917
Ensembl chr16:66,655,421...67,620,908
JBrowse link
G Caln1 calneuron 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CALN1 mRNA CTD PMID:22079614 NCBI chr 5:130,369,404...130,846,325
Ensembl chr 5:130,369,455...130,847,412
JBrowse link
G Calr calreticulin increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CALR mRNA CTD PMID:22079614 NCBI chr 8:84,842,088...84,846,931
Ensembl chr 8:84,841,850...84,846,934
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CAMK2N1 mRNA CTD PMID:22079614 NCBI chr 4:138,455,148...138,460,126
Ensembl chr 4:138,454,314...138,460,123
JBrowse link
G Capn15 calpain 15 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CAPN15 mRNA CTD PMID:22079614 NCBI chr17:25,958,364...25,985,874
Ensembl chr17:25,958,364...25,985,796
JBrowse link
G Capn2 calpain 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CAPN2 mRNA CTD PMID:22079614 NCBI chr 1:182,467,253...182,517,610
Ensembl chr 1:182,467,260...182,517,608
JBrowse link
G Capn6 calpain 6 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CAPN6 mRNA CTD PMID:22079614 NCBI chr  X:143,802,236...143,827,412
Ensembl chr  X:143,802,231...143,827,414
JBrowse link
G Card14 caspase recruitment domain family, member 14 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CARD14 mRNA CTD PMID:22079614 NCBI chr11:119,307,093...119,345,379
Ensembl chr11:119,307,768...119,345,375
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CARS1 mRNA CTD PMID:22079614 NCBI chr 7:143,557,230...143,600,090
Ensembl chr 7:143,557,230...143,600,090
JBrowse link
G Casp3 caspase 3 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CASP3 mRNA CTD PMID:22079614 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CASP9 mRNA CTD PMID:22079614 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CAT mRNA CTD PMID:16709600 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cbr4 carbonyl reductase 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CBR4 mRNA CTD PMID:22079614 NCBI chr 8:61,487,734...61,503,500
Ensembl chr 8:61,487,734...61,506,694
JBrowse link
G Ccdc170 coiled-coil domain containing 170 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCDC170 mRNA CTD PMID:22079614 NCBI chr10:4,482,515...4,564,498
Ensembl chr10:4,482,502...4,562,231
JBrowse link
G Ccdc3 coiled-coil domain containing 3 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CCDC3 mRNA CTD PMID:22079614 NCBI chr 2:5,137,311...5,235,967
Ensembl chr 2:5,137,776...5,230,878
JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCDC80 mRNA CTD PMID:22079614 NCBI chr16:45,093,407...45,127,924
Ensembl chr16:45,093,402...45,128,077
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
increases expression
ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]]; [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of CCL2 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CCL2 protein
CTD PMID:11230753 PMID:16997883 PMID:20940016 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions EXP 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCN3 mRNA CTD PMID:22079614 NCBI chr15:54,745,910...54,753,762
Ensembl chr15:54,745,702...54,754,039
JBrowse link
G Ccn6 cellular communication network factor 6 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCN6 mRNA CTD PMID:22079614 NCBI chr10:39,150,970...39,174,376
Ensembl chr10:39,150,970...39,163,794
JBrowse link
G Ccna1 cyclin A1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CCNA1 mRNA CTD PMID:22079614 NCBI chr 3:55,045,469...55,057,634
Ensembl chr 3:55,045,469...55,055,501
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCND2 mRNA CTD PMID:22079614 NCBI chr 6:127,125,162...127,152,188
Ensembl chr 6:127,125,162...127,152,193
JBrowse link
G Cd244a CD244 molecule A increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CD244 mRNA CTD PMID:22079614 NCBI chr 1:171,558,718...171,585,316
Ensembl chr 1:171,559,193...171,609,746
JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CD74 mRNA CTD PMID:22079614 NCBI chr18:60,803,849...60,812,652
Ensembl chr18:60,803,848...60,812,652
JBrowse link
G Cd9 CD9 antigen increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CD9 mRNA CTD PMID:22079614 NCBI chr 6:125,460,266...125,494,760
Ensembl chr 6:125,460,266...125,494,791
JBrowse link
G Cdh22 cadherin 22 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDH22 mRNA CTD PMID:22079614 NCBI chr 2:165,111,501...165,234,924
Ensembl chr 2:165,111,507...165,234,853
JBrowse link
G Cdh4 cadherin 4 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDH4 mRNA CTD PMID:22079614 NCBI chr 2:179,442,423...179,899,377
Ensembl chr 2:179,442,431...179,899,373
JBrowse link
G Cdh6 cadherin 6 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CDH6 mRNA CTD PMID:22079614 NCBI chr15:13,028,699...13,176,407
Ensembl chr15:13,028,701...13,173,675
JBrowse link
G Cdk2 cyclin-dependent kinase 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDK2 mRNA CTD PMID:22079614 NCBI chr10:128,697,938...128,705,051
Ensembl chr10:128,697,939...128,705,031
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDKN1A mRNA CTD PMID:22079614 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdon cell adhesion molecule-related/down-regulated by oncogenes increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CDON mRNA CTD PMID:20147733 NCBI chr 9:35,421,528...35,507,652
Ensembl chr 9:35,421,128...35,507,652
JBrowse link
G Cdx1 caudal type homeobox 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDX1 mRNA CTD PMID:22079614 NCBI chr18:61,018,862...61,036,199
Ensembl chr18:61,018,862...61,036,199
JBrowse link
G Cebpg CCAAT/enhancer binding protein (C/EBP), gamma increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CEBPG mRNA CTD PMID:22079614 NCBI chr 7:35,046,422...35,056,566
Ensembl chr 7:35,046,422...35,056,573
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CFLAR protein alternative form CTD PMID:16709600 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Cga glycoprotein hormones, alpha subunit increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CGA mRNA CTD PMID:8404651 PMID:21467749 PMID:22079614 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370
JBrowse link
G Cgn cingulin increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CGN mRNA CTD PMID:22079614 NCBI chr 3:94,760,069...94,787,725
Ensembl chr 3:94,760,069...94,786,515
JBrowse link
G Chn1 chimerin 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CHN1 mRNA CTD PMID:22079614 NCBI chr 2:73,610,660...73,775,367
Ensembl chr 2:73,610,660...73,775,346
JBrowse link
G Chp1 calcineurin-like EF hand protein 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CHP1 mRNA CTD PMID:22079614 NCBI chr 2:119,547,707...119,587,024
Ensembl chr 2:119,547,697...119,587,027
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CIDEA mRNA CTD PMID:22079614 NCBI chr18:67,343,564...67,367,794
Ensembl chr18:67,343,604...67,367,785
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CIDEC protein CTD PMID:21097823 NCBI chr 6:113,424,634...113,435,760
Ensembl chr 6:113,424,634...113,435,760
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CKMT2 mRNA CTD PMID:22079614 NCBI chr13:91,853,386...91,876,923
Ensembl chr13:91,853,387...91,876,885
JBrowse link
G Cldn1 claudin 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CLDN1 mRNA CTD PMID:22079614 NCBI chr16:26,356,645...26,371,839
Ensembl chr16:26,356,642...26,371,841
JBrowse link
G Cldn5 claudin 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CLDN5 mRNA CTD PMID:20711499 NCBI chr16:18,776,847...18,778,262
Ensembl chr16:18,776,847...18,778,262
JBrowse link
G Clgn calmegin increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CLGN mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 8:83,389,790...83,428,552
Ensembl chr 8:83,389,867...83,428,552
JBrowse link
G Clic3 chloride intracellular channel 3 multiple interactions
increases expression
ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CLIC3 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CLIC3 mRNA
CTD PMID:16997883 PMID:22079614 NCBI chr 2:25,456,843...25,458,777
Ensembl chr 2:25,456,838...25,458,776
JBrowse link
G Cmklr1 chemokine-like receptor 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CMKLR1 mRNA CTD PMID:20147733 NCBI chr 5:113,612,355...113,650,475
Ensembl chr 5:113,612,354...113,650,426
JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CNIH3 mRNA CTD PMID:22079614 NCBI chr 1:181,350,459...181,460,641
Ensembl chr 1:181,352,628...181,460,641
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CNR1 mRNA CTD PMID:22079614 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Col15a1 collagen, type XV, alpha 1 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL15A1 mRNA CTD PMID:16997883 NCBI chr 4:47,207,655...47,313,167
Ensembl chr 4:47,208,161...47,313,167
JBrowse link
G Col4a4 collagen, type IV, alpha 4 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of COL4A4 mRNA CTD PMID:22079614 NCBI chr 1:82,448,419...82,587,034
Ensembl chr 1:82,448,423...82,586,849
JBrowse link
G Col4a6 collagen, type IV, alpha 6 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL4A6 mRNA CTD PMID:16997883 NCBI chr  X:141,165,403...141,474,095
Ensembl chr  X:141,165,403...141,474,076
JBrowse link
G Col6a3 collagen, type VI, alpha 3 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of COL6A3 mRNA CTD PMID:22079614 NCBI chr 1:90,766,860...90,844,001
Ensembl chr 1:90,765,923...90,843,971
JBrowse link
G Col7a1 collagen, type VII, alpha 1 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL7A1 mRNA CTD PMID:16997883 NCBI chr 9:108,953,586...108,984,875
Ensembl chr 9:108,953,586...108,984,875
JBrowse link
G Colec12 collectin sub-family member 12 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of COLEC12 mRNA CTD PMID:22079614 NCBI chr18:9,707,648...9,877,995
Ensembl chr18:9,707,595...9,882,644
JBrowse link
G Coro2a coronin, actin binding protein 2A decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CORO2A mRNA CTD PMID:22079614 NCBI chr 4:46,536,937...46,601,929
Ensembl chr 4:46,536,937...46,602,202
JBrowse link
G Cpm carboxypeptidase M decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CPM mRNA CTD PMID:22079614 NCBI chr10:117,629,500...117,687,352
Ensembl chr10:117,629,500...117,687,352
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CRADD mRNA CTD PMID:22079614 NCBI chr10:95,174,739...95,324,138
Ensembl chr10:95,174,746...95,324,133
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of CREB1 protein CTD PMID:18467523 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]] CTD PMID:2153673 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CRHBP mRNA CTD PMID:22079614 NCBI chr13:95,431,376...95,444,831
Ensembl chr13:95,431,371...95,444,924
JBrowse link
G Cst6 cystatin E/M multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of CST6 mRNA CTD PMID:16997883 NCBI chr19:5,344,705...5,349,574
Ensembl chr19:5,344,705...5,349,574
JBrowse link
G Ctnna2 catenin (cadherin associated protein), alpha 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CTNNA2 mRNA CTD PMID:22079614 NCBI chr 6:76,881,637...77,979,815
Ensembl chr 6:76,881,637...77,979,699
JBrowse link
G Cttnbp2 cortactin binding protein 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CTTNBP2 mRNA CTD PMID:22079614 NCBI chr 6:18,366,471...18,515,217
Ensembl chr 6:18,366,478...18,514,843
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CUX2 mRNA CTD PMID:22079614 NCBI chr 5:121,857,962...122,050,415
Ensembl chr 5:121,856,366...122,050,102
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CX3CL1 mRNA CTD PMID:22079614 NCBI chr 8:94,772,180...94,782,427
Ensembl chr 8:94,772,009...94,782,427
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL10 mRNA CTD PMID:22079614 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 decreases expression
increases expression
EXP
ISO
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CXCL12 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL12 mRNA
CTD PMID:20711499 PMID:22079614 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO daidzein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA]; Estradiol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA]; Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA] CTD PMID:21056929 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYCS mRNA CTD PMID:22079614 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
EXP
ISO
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]]; [NR5A1 protein co-treated with 20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11A1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11A1 mRNA; Hydrocarbons, Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein
Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP11A1 protein
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP11A1 protein]
CTD PMID:20147733 PMID:21126571 PMID:21610156 PMID:21664964 PMID:21726595 PMID:22546480 PMID:24014645 PMID:24328340 PMID:24740604 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 multiple interactions EXP [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11B1 mRNA CTD PMID:21610156 NCBI chr15:74,834,892...74,841,643
Ensembl chr15:74,834,125...74,841,643
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11B2 mRNA CTD PMID:22079614 NCBI chr15:74,850,618...74,856,231
Ensembl chr15:74,851,010...74,856,318
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
[4-nitro-3-phenylphenol co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of CYP17A1 protein; Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]]; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP17A1 mRNA; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]
CTD PMID:18336853 PMID:21610156 PMID:21726595 PMID:22079614 PMID:22546480 PMID:24014645 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO
EXP
[vinclozolin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA; Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]; Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA]; bisphenol A inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]; formestane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]; Methoxychlor inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]
[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 protein
CTD PMID:10746939 PMID:18815356 PMID:21126571 PMID:21610156 PMID:22120136 PMID:23583632 PMID:28859905 PMID:30951242 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 protein
CTD PMID:7588239 PMID:22079614 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP21A2 mRNA
[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP21A1 mRNA
Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP21A2 mRNA]
CTD PMID:21610156 PMID:22079614 PMID:22546480 NCBI chr17:34,801,348...34,804,426
Ensembl chr17:34,801,348...34,804,561
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP27A1 mRNA CTD PMID:22079614 NCBI chr 1:74,713,148...74,737,897
Ensembl chr 1:74,713,574...74,737,892
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP2E1 mRNA CTD PMID:22079614 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP2F1 mRNA CTD PMID:22079614 NCBI chr 7:27,119,955...27,133,660
Ensembl chr 7:27,119,909...27,133,660
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP3A5 mRNA CTD PMID:22079614 NCBI chr 5:137,892,933...137,925,610
Ensembl chr 5:137,892,932...137,921,619
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression
multiple interactions
ISO
EXP
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP51A1 mRNA
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 mRNA; [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 protein; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 mRNA]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 protein]
CTD PMID:18467523 PMID:22079614 NCBI chr 5:4,080,674...4,104,697
Ensembl chr 5:4,081,145...4,104,746
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP8B1 mRNA CTD PMID:22079614 NCBI chr 9:121,914,356...121,916,305
Ensembl chr 9:121,914,356...121,916,305
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYTH1 mRNA CTD PMID:22079614 NCBI chr11:118,164,170...118,248,616
Ensembl chr11:118,132,019...118,248,592
JBrowse link
G Dach2 dachshund family transcription factor 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DACH2 mRNA CTD PMID:22079614 NCBI chr  X:113,297,496...113,836,386
Ensembl chr  X:113,297,510...113,836,386
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DACT1 mRNA CTD PMID:22079614 NCBI chr12:71,309,884...71,320,107
Ensembl chr12:71,309,884...71,320,107
JBrowse link
G Dbil5 diazepam binding inhibitor-like 5 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DBIL5P mRNA CTD PMID:22079614 NCBI chr11:76,217,613...76,218,665
Ensembl chr11:76,217,608...76,218,666
JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DCAF12L1 mRNA CTD PMID:22079614 NCBI chr  X:44,786,567...44,790,197
Ensembl chr  X:44,786,570...44,790,197
JBrowse link
G Dcbld2 discoidin, CUB and LCCL domain containing 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DCBLD2 mRNA CTD PMID:22079614 NCBI chr16:58,408,535...58,469,745
Ensembl chr16:58,408,443...58,469,727
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DGAT2 mRNA CTD PMID:22079614 NCBI chr 7:99,153,663...99,182,713
Ensembl chr 7:99,153,658...99,182,719
JBrowse link
G Dgkb diacylglycerol kinase, beta increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DGKB mRNA CTD PMID:22079614 NCBI chr12:37,880,169...38,634,239
Ensembl chr12:37,817,726...38,634,239
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DHCR24 mRNA CTD PMID:22079614 NCBI chr 4:106,561,038...106,589,113
Ensembl chr 4:106,561,038...106,589,113
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DHCR7 mRNA CTD PMID:22079614 NCBI chr 7:143,823,167...143,848,410
Ensembl chr 7:143,823,145...143,848,410
JBrowse link
G Dhrs2 dehydrogenase/reductase member 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DHRS2 mRNA CTD PMID:22079614 NCBI chr14:55,222,007...55,241,440
Ensembl chr14:55,222,007...55,241,435
JBrowse link
G Dhrs3 dehydrogenase/reductase (SDR family) member 3 multiple interactions ISO 7-propyl spirolactone inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein]; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein; Aldosterone promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA] CTD PMID:23275455 NCBI chr 4:144,892,534...144,928,209
Ensembl chr 4:144,892,827...144,928,209
JBrowse link
G Dio2 deiodinase, iodothyronine, type II multiple interactions
increases activity
ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of and results in increased activity of DIO2 protein
8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]]; Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]]
CTD PMID:11425850 PMID:18420745 NCBI chr12:90,724,552...90,739,038
Ensembl chr12:90,724,552...90,738,438
JBrowse link
G Dio3 deiodinase, iodothyronine type III multiple interactions ISO Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein] CTD PMID:18420745 NCBI chr12:110,279,230...110,281,097
Ensembl chr12:110,279,068...110,281,097
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DKK1 mRNA CTD PMID:22079614 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNAH5 mRNA CTD PMID:22079614 NCBI chr15:28,154,854...28,472,045
Ensembl chr15:28,203,752...28,472,052
JBrowse link
G Dnajb3 DnaJ heat shock protein family (Hsp40) member B3 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DNAJB3 mRNA CTD PMID:22079614 NCBI chr 1:88,204,732...88,205,748
Ensembl chr 1:88,204,732...88,205,782
JBrowse link
G Dnajb7 DnaJ heat shock protein family (Hsp40) member B7 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNAJB7 mRNA CTD PMID:22079614 NCBI chr15:81,407,088...81,408,273
Ensembl chr15:81,406,926...81,408,299
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNAJB9 mRNA CTD PMID:22079614 NCBI chr12:44,205,897...44,210,068
Ensembl chr12:44,205,559...44,210,326
JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNER mRNA CTD PMID:22079614 NCBI chr 1:84,369,839...84,696,221
Ensembl chr 1:84,369,839...84,696,221
JBrowse link
G Dock11 dedicator of cytokinesis 11 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DOCK11 mRNA CTD PMID:22079614 NCBI chr  X:35,887,271...36,076,570
Ensembl chr  X:35,888,832...36,076,562
JBrowse link
G Dok5 docking protein 5 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DOK5 mRNA CTD PMID:22079614 NCBI chr 2:170,731,807...170,879,775
Ensembl chr 2:170,731,807...170,879,769
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DUSP1 mRNA CTD PMID:22079614 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Dusp16 dual specificity phosphatase 16 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DUSP16 mRNA CTD PMID:22079614 NCBI chr 6:134,715,468...134,807,063
Ensembl chr 6:134,715,468...134,792,625
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DUSP4 mRNA CTD PMID:20147733 NCBI chr 8:34,807,610...34,819,894
Ensembl chr 8:34,807,297...34,819,894
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DUSP6 mRNA CTD PMID:22079614 NCBI chr10:99,263,231...99,267,489
Ensembl chr10:99,263,231...99,267,489
JBrowse link
G Ebp phenylalkylamine Ca2+ antagonist (emopamil) binding protein increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EBP mRNA CTD PMID:22079614 NCBI chr  X:8,185,329...8,193,512
Ensembl chr  X:8,185,329...8,193,512
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ECHS1 mRNA CTD PMID:22079614 NCBI chr 7:140,105,710...140,116,421
Ensembl chr 7:140,105,710...140,116,476
JBrowse link
G Egf epidermal growth factor multiple interactions EXP EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]] CTD PMID:18467523 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGFR mRNA CTD PMID:22079614 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Egr1 early growth response 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGR1 mRNA CTD PMID:22079614 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Egr2 early growth response 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGR2 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr10:67,534,469...67,542,188
Ensembl chr10:67,535,475...67,542,188
JBrowse link
G Elp1 elongator complex protein 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ELP1 mRNA CTD PMID:22079614 NCBI chr 4:56,746,547...56,802,569
Ensembl chr 4:56,749,680...56,802,331
JBrowse link
G Emp2 epithelial membrane protein 2 multiple interactions
decreases expression
ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of EMP2 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EMP2 mRNA
CTD PMID:16997883 PMID:22079614 NCBI chr16:10,281,749...10,313,968
Ensembl chr16:10,281,749...10,313,968
JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ENOX1 mRNA CTD PMID:20147733 NCBI chr14:77,156,248...77,721,763
Ensembl chr14:77,156,763...77,721,760
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EP300 mRNA CTD PMID:22079614 NCBI chr15:81,586,209...81,652,077
Ensembl chr15:81,585,351...81,652,077
JBrowse link
G Epg5 ectopic P-granules autophagy protein 5 homolog (C. elegans) decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EPG5 mRNA CTD PMID:20147733 NCBI chr18:77,938,409...78,037,325
Ensembl chr18:77,938,465...78,035,013
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EPHX1 mRNA CTD PMID:22079614 NCBI chr 1:180,989,556...181,017,569
Ensembl chr 1:180,976,210...181,020,904
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ERAP1 mRNA CTD PMID:22079614 NCBI chr13:74,639,573...74,693,205
Ensembl chr13:74,639,568...74,693,201
JBrowse link
G Erf Ets2 repressor factor decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ERF mRNA CTD PMID:22079614 NCBI chr 7:25,242,560...25,251,104
Ensembl chr 7:25,242,561...25,250,761
JBrowse link
G Esr2 estrogen receptor 2 (beta) decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ESR2 mRNA CTD PMID:22079614 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Esrra estrogen related receptor, alpha increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ESRRA mRNA CTD PMID:23166782 NCBI chr19:6,910,977...6,922,048
Ensembl chr19:6,910,977...6,921,813
Ensembl chr19:6,910,977...6,921,813
JBrowse link
G Esrrg estrogen-related receptor gamma decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ESRRG mRNA CTD PMID:22079614 NCBI chr 1:187,608,510...188,214,885
Ensembl chr 1:187,608,791...188,214,885
JBrowse link
G Etnppl ethanolamine phosphate phospholyase increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ETNPPL mRNA CTD PMID:22079614 NCBI chr 3:130,617,448...130,635,750
Ensembl chr 3:130,617,448...130,637,521
JBrowse link
G Etv1 ets variant 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ETV1 mRNA CTD PMID:20147733 NCBI chr12:38,780,082...38,870,483
Ensembl chr12:38,779,380...38,870,484
JBrowse link
G Etv5 ets variant 5 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ETV5 mRNA CTD PMID:22079614 NCBI chr16:22,381,313...22,439,570
Ensembl chr16:22,381,309...22,439,719
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression
multiple interactions
ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EZH2 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EZH2 protein
[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in decreased expression of EZH2 mRNA; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in decreased expression of EZH2 protein; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA]
CTD PMID:21903722 NCBI chr 6:47,530,274...47,595,270
Ensembl chr 6:47,530,139...47,595,341
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of F2RL2 mRNA CTD PMID:20147733 NCBI chr13:95,696,920...95,702,768
Ensembl chr13:95,696,853...95,702,739
JBrowse link
G Fabp1 fatty acid binding protein 1, liver increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FABP1 mRNA CTD PMID:22079614 NCBI chr 6:71,199,879...71,205,034
Ensembl chr 6:71,199,827...71,205,023
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FADS1 mRNA CTD PMID:22079614 NCBI chr19:10,182,877...10,196,874
Ensembl chr19:10,182,888...10,196,877
JBrowse link
G Fam155a family with sequence similarity 155, member A increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NALF1 mRNA CTD PMID:22079614 NCBI chr 8:9,206,006...9,773,329
Ensembl chr 8:9,205,902...9,771,161
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FASLG protein CTD PMID:16709600 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fbln1 fibulin 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FBLN1 mRNA CTD PMID:15774544 NCBI chr15:85,205,949...85,286,294
Ensembl chr15:85,205,949...85,286,535
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions ISO [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA] CTD PMID:23275455 NCBI chr15:58,175,879...58,214,892
Ensembl chr15:58,175,879...58,214,932
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDFT1 mRNA CTD PMID:22079614 NCBI chr14:63,145,150...63,181,687
Ensembl chr14:63,145,150...63,179,578
JBrowse link
G Fdx1 ferredoxin 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDX1 mRNA CTD PMID:22079614 NCBI chr 9:51,943,023...51,963,602
Ensembl chr 9:51,943,306...51,963,556
JBrowse link
G Fdxr ferredoxin reductase increases expression
multiple interactions
EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein
Hydrocarbons, Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein]
CTD PMID:24740604 NCBI chr11:115,268,024...115,277,101
Ensembl chr11:115,268,024...115,277,050
JBrowse link
G Fer1l6 fer-1-like 6 (C. elegans) increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FER1L6 mRNA CTD PMID:20147733 NCBI chr15:58,510,048...58,665,087
Ensembl chr15:58,510,048...58,665,092
JBrowse link
G Fgf10 fibroblast growth factor 10 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FGF10 mRNA CTD PMID:20147733 NCBI chr13:118,714,699...118,792,573
Ensembl chr13:118,669,791...118,792,115
JBrowse link
G Fgf13 fibroblast growth factor 13 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FGF13 mRNA CTD PMID:22079614 NCBI chr  X:59,062,139...59,585,572
Ensembl chr  X:59,062,145...59,568,071
JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FGF9 mRNA CTD PMID:22079614 NCBI chr14:58,070,671...58,112,854
Ensembl chr14:58,070,547...58,112,720
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FHL2 mRNA CTD PMID:22079614 NCBI chr 1:43,123,071...43,198,343
Ensembl chr 1:43,123,074...43,196,984
JBrowse link
G Flot1 flotillin 1 multiple interactions ISO [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FLOT1 mRNA CTD PMID:16997883 NCBI chr17:35,823,320...35,832,789
Ensembl chr17:35,823,230...35,832,791
JBrowse link
G Flot2 flotillin 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FLOT2 mRNA CTD PMID:22079614 NCBI chr11:78,037,931...78,060,434
Ensembl chr11:78,037,931...78,060,434
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FN1 mRNA CTD PMID:22079614 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 protein; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein]; Hydrogen Peroxide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 mRNA]; Hydrogen Peroxide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 protein] CTD PMID:16709600 NCBI chr 3:52,268,337...52,350,109
Ensembl chr 3:52,268,336...52,353,221
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] inhibits the reaction [Hydrogen Peroxide results in increased expression of FOXO3 mRNA]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] inhibits the reaction [Hydrogen Peroxide results in increased expression of FOXO3 protein]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA] CTD PMID:16709600 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Foxr1 forkhead box R1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FOXR1 mRNA CTD PMID:22079614 NCBI chr 9:44,434,234...44,440,868
Ensembl chr 9:44,433,773...44,441,136
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FRAS1 mRNA CTD PMID:22079614 NCBI chr 5:96,373,777...96,784,733
Ensembl chr 5:96,373,955...96,784,728
JBrowse link
G Fshb follicle stimulating hormone beta increases expression
multiple interactions
ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FSHB mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FSHB protein
Tetrachlorodibenzodioxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FSHB mRNA]
CTD PMID:8404651 PMID:10746652 PMID:21467749 NCBI chr 2:107,055,986...107,059,651
Ensembl chr 2:107,056,140...107,059,656
JBrowse link
G Fzd10 frizzled class receptor 10 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FZD10 mRNA CTD PMID:22079614 NCBI chr 5:128,601,106...128,604,093
Ensembl chr 5:128,600,844...128,604,093
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FZD4 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 7:89,404,366...89,410,110
Ensembl chr 7:89,404,355...89,413,134
JBrowse link
G Fzd7 frizzled class receptor 7 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FZD7 mRNA CTD PMID:22079614 NCBI chr 1:59,482,147...59,486,955
Ensembl chr 1:59,482,424...59,486,955
JBrowse link
G Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GABBR2 mRNA CTD PMID:22079614 NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873
JBrowse link
G Gabra4 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GABRA4 mRNA CTD PMID:22079614 NCBI chr 5:71,569,734...71,658,308
Ensembl chr 5:71,569,749...71,658,308
JBrowse link
G Gabrg1 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GABRG1 mRNA CTD PMID:22079614 NCBI chr 5:70,751,047...70,842,617
Ensembl chr 5:70,751,047...70,842,617
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha multiple interactions ISO [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of GADD45A mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of GADD45A protein CTD PMID:16709600 NCBI chr 6:67,035,096...67,037,407
Ensembl chr 6:67,035,096...67,037,457
JBrowse link
G Galnt12 polypeptide N-acetylgalactosaminyltransferase 12 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GALNT12 mRNA CTD PMID:20147733 NCBI chr 4:47,091,894...47,123,058
Ensembl chr 4:47,091,909...47,123,070
JBrowse link
G Galr1 galanin receptor 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GALR1 mRNA CTD PMID:22079614 NCBI chr18:82,392,496...82,406,777
Ensembl chr18:82,392,380...82,406,777
JBrowse link
G Gap43 growth associated protein 43 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GAP43 mRNA CTD PMID:20147733 NCBI chr16:42,248,552...42,340,651
Ensembl chr16:42,248,442...42,340,651
JBrowse link
G Gck glucokinase decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GCK mRNA CTD PMID:22079614 NCBI chr11:5,900,816...5,950,081
Ensembl chr11:5,900,820...5,950,081
JBrowse link
G Gcsam germinal center associated, signaling and motility increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GCSAM mRNA CTD PMID:22079614 NCBI chr16:45,610,440...45,622,867
Ensembl chr16:45,610,380...45,622,867
JBrowse link
G Gdf10 growth differentiation factor 10 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF10 mRNA CTD PMID:22079614 NCBI chr14:33,923,587...33,936,514
Ensembl chr14:33,923,587...33,937,983
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF15 mRNA CTD PMID:22079614 NCBI chr 8:70,629,393...70,632,470
Ensembl chr 8:70,629,393...70,632,456
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions
ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GFAP mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]
CTD PMID:15994020 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Gfpt2 glutamine fructose-6-phosphate transaminase 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GFPT2 mRNA CTD PMID:20147733 NCBI chr11:49,794,155...49,838,620
Ensembl chr11:49,794,178...49,838,613
JBrowse link
G Gimap8 GTPase, IMAP family member 8 decreases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GIMAP8 mRNA CTD PMID:22079614 NCBI chr 6:48,647,186...48,660,875
Ensembl chr 6:48,647,234...48,660,875
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GJA1 mRNA CTD PMID:22079614 NCBI chr10:56,377,300...56,390,419
Ensembl chr10:56,377,330...56,402,513
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GJB2 mRNA CTD PMID:22079614 NCBI chr14:57,098,602...57,104,702
Ensembl chr14:57,098,600...57,104,702
JBrowse link
G Gk glycerol kinase increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GK mRNA CTD PMID:22079614 NCBI chr  X:85,701,937...85,776,819
Ensembl chr  X:85,701,937...85,776,819
JBrowse link
G Glipr1 GLI pathogenesis-related 1 (glioma) increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GLIPR1 mRNA CTD PMID:20147733 NCBI chr10:111,985,448...112,002,639
Ensembl chr10:111,985,448...112,002,631
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G Glrx glutaredoxin increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GLRX mRNA CTD PMID:22079614 NCBI chr13:75,839,885...75,850,151
Ensembl chr13:75,839,868...75,850,154
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G Gm13754 predicted gene 13754 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CPO mRNA CTD PMID:22079614 NCBI chr 1:63,917,881...63,934,788
Ensembl chr 1:63,917,848...63,935,932
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G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 multiple interactions