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Accession:CHEBI:8405 term browser browse the term
Definition:An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
Synonyms:exact_synonym: N(4)-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
 related_synonym: 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline;   8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline;   8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline;   Formula=C15H21N3O;   InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3;   InChIKey=INDBQLZJXZLFIT-UHFFFAOYSA-N;   Neo-Quipenyl;   Primachin;   Primachinum;   Primaquin;   SMILES=COc1cc(NC(C)CCCN)c2ncccc2c1;   primaquina;   primaquinum
 alt_id: CHEBI:110389
 xref: Beilstein:19337 "Beilstein";   CAS:90-34-6 "ChemIDplus";   CAS:90-34-6 "KEGG COMPOUND";   CAS:90-34-6 "NIST Chemistry WebBook";   DrugBank:DB01087;   Drug_Central:2266 "DrugCentral";   Gmelin:751542 "Gmelin";   HMDB:HMDB0015219;   KEGG:C07627;   KEGG:D08420;   LINCS:LSM-1649
 xref_mesh: MESH:D011319
 xref: PMID:10928454 "Europe PMC";   PMID:11303037 "Europe PMC";   PMID:12036132 "Europe PMC";   PMID:14917959 "Europe PMC";   PMID:15494911 "Europe PMC";   PMID:16537060 "Europe PMC";   PMID:17253504 "Europe PMC";   PMID:18930565 "Europe PMC";   PMID:19114311 "Europe PMC";   PMID:2210868 "Europe PMC";   PMID:28279180 "Europe PMC";   PMID:28289025 "Europe PMC";   PMID:8920977 "Europe PMC";   Reaxys:19337 "Reaxys";   Wikipedia:Primaquine

show annotations for term's descendants       view all columns           Sort by:
primaquine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      application 19353
        refrigerant 17254
          ammonia 16703
            organic amino compound 16702
              aromatic amine 13610
                aminoquinoline 1567
                  primaquine 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    main group molecular entity 19637
                      s-block molecular entity 19397
                        hydrogen molecular entity 19386
                          hydrides 18356
                            inorganic hydride 17216
                              pnictogen hydride 17180
                                nitrogen hydride 17014
                                  azane 16706
                                    ammonia 16703
                                      organic amino compound 16702
                                        polyamine 8084
                                          diamine 8011
                                            N-substituted diamine 294
                                              primaquine 15
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.