CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole
Accession: CHEBI:83999
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Definition: A member of the class of triazoles that is 1,2,4-triazole substituted at position 1 by a 2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl group.
Synonyms: exact_synonym: 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1H-1,2,4-triazole
related_synonym: Formula=C13H11Cl2F4N3O; InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2; InChIKey=LQDARGUHUSPFNL-UHFFFAOYSA-N; SMILES=FC(F)C(F)(F)OCC(Cn1cncn1)c1ccc(Cl)cc1Cl
xref: PPDB:626
G
Ahr
aryl hydrocarbon receptor
increases activity
ISO
tetraconazole results in increased activity of AHR protein
CTD
PMID:20143881
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
affects activity
ISO
tetraconazole affects the activity of CYP2C19 protein
CTD
PMID:23611293
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Hif1a
hypoxia inducible factor 1 subunit alpha
increases activity
ISO
tetraconazole results in increased activity of HIF1A protein
CTD
PMID:20143881
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Il17a
interleukin 17A
multiple interactions
ISO
tetraconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]
CTD
PMID:22289359
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
G
Rora
RAR-related orphan receptor A
multiple interactions
ISO
tetraconazole binds to and results in decreased activity of RORA protein
CTD
PMID:22289359
NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19918
chemical entity
19916
atom
19916
nonmetal atom
19852
oxygen atom
19586
oxygen molecular entity
19586
organooxygen compound
19217
ether
17308
1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole
5
(R)-tetraconazole +
5
(S)-tetraconazole +
5
Path 2
CHEBI ontology
19918
subatomic particle
19916
composite particle
19916
hadron
19916
baryon
19916
nucleon
19916
atomic nucleus
19916
atom
19916
main group element atom
19866
p-block element atom
19866
carbon group element atom
19811
carbon atom
19806
organic molecular entity
19806
organic molecule
19758
organic cyclic compound
19565
carbocyclic compound
18616
benzenoid aromatic compound
17993
benzenes
17844
chlorobenzenes
14864
dichlorobenzene
11551
1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole
5
(R)-tetraconazole +
5
(S)-tetraconazole +
5