|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions decreases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid] |
CTD |
PMID:27469509 |
|
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
|
|
G |
Lepr |
leptin receptor |
affects abundance |
ISO |
LEPR affects the abundance of Argininosuccinic Acid |
CTD |
PMID:20567778 |
|
NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
|
|
|
G |
Ache |
acetylcholinesterase |
increases expression multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased expression of ACHE protein [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of ACHE protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of ACHE protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in increased expression of ACHE protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased expression of ACHE protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of ACHE protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of ACHE protein]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased expression of ACHE protein] |
CTD |
PMID:32428650 |
|
NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
|
|
G |
Ada |
adenosine deaminase |
multiple interactions increases activity |
EXP |
[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ADA protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ADA protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased activity of ADA protein] |
CTD |
PMID:32428650 |
|
NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
|
|
G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
NG-Nitroarginine Methyl Ester inhibits the reaction [AGT protein results in increased activity of PARP1 protein] |
CTD |
PMID:15502880 |
|
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
|
|
G |
Agtr1b |
angiotensin II receptor, type 1b |
increases expression multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased expression of AGTR1B protein Sildenafil Citrate inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of AGTR1B protein]; tangeretin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of AGTR1B protein] |
CTD |
PMID:32479886 |
|
NCBI chr 2:105,149,020...105,224,335
Ensembl chr 2:105,149,020...105,224,295
|
|
G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
EXP |
[NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in decreased expression of CASP9 protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of CASP9 protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased expression of CASP9 protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of CASP9 protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of CASP9 protein]; NG-Nitroarginine Methyl Ester inhibits the reaction [bisphenol A results in increased expression of CASP9 protein] |
CTD |
PMID:32428650 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 mRNA; [Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein]]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 mRNA]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein] |
CTD |
PMID:29423081 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
|
|
G |
Cybb |
cytochrome b-245 beta chain |
increases expression multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased expression of CYBB protein Sildenafil Citrate inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of CYBB protein]; tangeretin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of CYBB protein] |
CTD |
PMID:32479886 |
|
NCBI chr X:14,578,330...14,610,049
Ensembl chr X:14,578,264...14,612,547
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
NG-Nitroarginine Methyl Ester inhibits the reaction [Folic Acid inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]] |
CTD |
PMID:28624453 |
|
NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
EXP |
[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG mRNA; [Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG protein; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG protein]]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG mRNA]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG protein] |
CTD |
PMID:29423081 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
NG-Nitroarginine Methyl Ester inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL1A mRNA] |
CTD |
PMID:32142722 |
|
NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
|
|
G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased expression of IL1B protein [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of IL1B protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of IL1B protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in increased expression of IL1B protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased expression of IL1B protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of IL1B protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of IL1B protein]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased expression of IL1B protein] |
CTD |
PMID:32428650 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA; [Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 protein; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 protein] |
CTD |
PMID:29423081 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Maoa |
monoamine oxidase A |
increases expression multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased expression of MAOA protein [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of MAOA protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of MAOA protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased expression of MAOA protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of MAOA protein]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased expression of MAOA protein] |
CTD |
PMID:32428650 |
|
NCBI chr X:6,554,698...6,620,722
Ensembl chr X:6,554,698...6,620,722
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA; [Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein]]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein] |
CTD |
PMID:29423081 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Nos3 |
nitric oxide synthase 3 |
decreases expression multiple interactions |
ISO EXP |
NG-Nitroarginine Methyl Ester results in decreased expression of NOS3 protein Sildenafil Citrate inhibits the reaction [NG-Nitroarginine Methyl Ester results in decreased expression of NOS3 protein]; tangeretin inhibits the reaction [NG-Nitroarginine Methyl Ester results in decreased expression of NOS3 protein] [Folic Acid co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of NOS3 protein |
CTD |
PMID:28624453 PMID:32479886 |
|
NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
|
|
G |
Panx3 |
pannexin 3 |
multiple interactions |
ISO |
NG-Nitroarginine Methyl Ester inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of PANX3 mRNA] |
CTD |
PMID:32142722 |
|
NCBI chr 8:40,126,379...40,137,390
Ensembl chr 8:40,126,342...40,137,390
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
NG-Nitroarginine Methyl Ester inhibits the reaction [AGT protein results in increased activity of PARP1 protein] |
CTD |
PMID:15502880 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
G |
Pde5a |
phosphodiesterase 5A |
increases activity multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased activity of PDE5A protein [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of PDE5A protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased activity of PDE5A protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of PDE5A protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased activity of PDE5A protein]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased activity of PDE5A protein] |
CTD |
PMID:32428650 |
|
NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
NG-Nitroarginine Methyl Ester inhibits the reaction [Folic Acid inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 mRNA]]; NG-Nitroarginine Methyl Ester inhibits the reaction [Folic Acid inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]] |
CTD |
PMID:28624453 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|
G |
Spn |
sialophorin |
multiple interactions increases expression |
EXP |
[NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in decreased expression of SPN protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of SPN protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in decreased expression of SPN protein; bisphenol A inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of SPN protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of SPN protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of SPN protein] |
CTD |
PMID:32428650 |
|
NCBI chr 1:198,572,999...198,585,664
Ensembl chr 1:198,572,999...198,577,226
|
|
G |
Star |
steroidogenic acute regulatory protein |
multiple interactions decreases expression |
EXP |
Sildenafil Citrate inhibits the reaction [NG-Nitroarginine Methyl Ester results in decreased expression of STAR protein]; tangeretin inhibits the reaction [NG-Nitroarginine Methyl Ester results in decreased expression of STAR protein] |
CTD |
PMID:32479886 |
|
NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
|
|
G |
Th |
tyrosine hydroxylase |
decreases expression |
ISO |
NG-Nitroarginine Methyl Ester results in decreased expression of TH protein |
CTD |
PMID:31187328 |
|
NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
EXP |
[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF mRNA; [Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of TNF protein; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein]]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of TNF protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of TNF protein]; NG-Nitroarginine Methyl Ester inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein]]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF mRNA]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein] |
CTD |
PMID:29423081 PMID:30529211 PMID:32428650 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Tp53 |
tumor protein p53 |
increases expression multiple interactions |
EXP |
NG-Nitroarginine Methyl Ester results in increased expression of TP53 protein [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of TP53 protein; [NG-Nitroarginine Methyl Ester co-treated with naringin] results in decreased expression of TP53 protein; bisphenol A inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of TP53 protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of TP53 protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester results in increased expression of TP53 protein]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased expression of TP53 protein] |
CTD |
PMID:32428650 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
decreases response to substance |
ISO |
TRPA1 gene mutant form results in decreased susceptibility to NG-Nitroarginine Methyl Ester |
CTD |
PMID:32634517 |
|
NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 mRNA; [Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein]]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 mRNA]; Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein] |
CTD |
PMID:29423081 |
|
NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
|
|
|
G |
Slco4c1 |
solute carrier organic anion transporter family, member 4C1 |
increases uptake |
ISO |
SLCO4C1 protein results in increased uptake of N,N-dimethylarginine |
CTD |
PMID:30865704 |
|
NCBI chr 9:104,301,935...104,350,262
Ensembl chr 9:104,299,277...104,350,308
|
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] |
CTD |
PMID:23011206 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] |
CTD |
PMID:23011206 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein] |
CTD |
PMID:32526215 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|
G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of VEGFA protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of VEGFA protein] |
CTD |
PMID:32526215 |
|
NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
|
|
|
G |
Edn1 |
endothelin 1 |
multiple interactions |
EXP |
S-methylthiocitrulline inhibits the reaction [EDN1 protein results in increased abundance of Nitric Oxide] |
CTD |
PMID:16380457 |
|
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
|
|
G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions decreases activity |
EXP ISO |
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the abundance of Sodium [S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine |
CTD |
PMID:11006970 PMID:12511180 |
|
NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
|
|
G |
Slc18a2 |
solute carrier family 18 member A2 |
multiple interactions |
EXP |
S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] |
CTD |
PMID:17683483 |
|
NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
|
|