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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile
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Accession:CHEBI:83920 term browser browse the term
Definition:A member of the class of triazoles that is 1-chloro-4-(3-phenylpropyl)benzene substituted at position 3 of the propyl moiety by cyano and 1,2,4-triazol-1-ylmethyl groups.
Synonyms:exact_synonym: 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile
 related_synonym: Formula=C19H17ClN4;   InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2;   InChIKey=RQDJADAKIFFEKQ-UHFFFAOYSA-N;   SMILES=Clc1ccc(CCC(Cn2cncn2)(C#N)c2ccccc2)cc1
 xref: PPDB:293


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fenbuconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta increases expression ISO fenbuconazole results in increased expression of ACTB mRNA CTD PMID:15942997 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G C5ar1 complement C5a receptor 1 decreases expression ISO fenbuconazole results in decreased expression of C5AR1 mRNA CTD PMID:15942997 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Calr calreticulin increases expression ISO fenbuconazole results in increased expression of CALR mRNA CTD PMID:15942997 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Cd63 Cd63 molecule increases expression ISO fenbuconazole results in increased expression of CD63 mRNA CTD PMID:15942997 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO fenbuconazole results in increased expression of COMT mRNA CTD PMID:15942997 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO fenbuconazole results in decreased activity of CYP19A1 protein CTD PMID:16996190 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO fenbuconazole results in increased expression of CYP2B10 protein
fenbuconazole binds to and results in increased activity of CYP2B10 protein
CTD PMID:16542693 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO fenbuconazole results in decreased expression of CYP7A1 mRNA CTD PMID:15942997 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO fenbuconazole results in increased expression of EEF1A1 mRNA CTD PMID:15942997 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO fenbuconazole binds to and results in increased activity of ESR1 protein CTD PMID:16626760 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO fenbuconazole binds to and results in increased activity of ESR2 protein CTD PMID:16626760 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig increases expression ISO fenbuconazole results in increased expression of FCER1G mRNA CTD PMID:15942997 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO fenbuconazole results in increased expression of GAPDH mRNA CTD PMID:15942997 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO fenbuconazole results in increased expression of HSPA1A mRNA CTD PMID:15942997
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO fenbuconazole results in increased expression of HSPD1 mRNA CTD PMID:15942997 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO fenbuconazole results in decreased expression of ICAM1 mRNA CTD PMID:15942997 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression ISO fenbuconazole results in increased expression of MAPK3 mRNA CTD PMID:15942997 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO fenbuconazole results in increased expression of MMP12 mRNA CTD PMID:15942997 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases expression ISO fenbuconazole results in increased expression of MPG mRNA CTD PMID:15942997 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G Msh3 mutS homolog 3 decreases expression ISO fenbuconazole results in decreased expression of MSH3 mRNA CTD PMID:15942997 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO fenbuconazole results in increased activity of NR1I2 protein CTD PMID:16565514 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Oat ornithine aminotransferase increases expression ISO fenbuconazole results in increased expression of OAT mRNA CTD PMID:15942997 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO fenbuconazole results in increased expression of PLAT mRNA CTD PMID:15942997 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Pou2f1 POU class 2 homeobox 1 increases expression ISO fenbuconazole results in increased expression of POU2F1 mRNA CTD PMID:15942997 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363
JBrowse link
G Rpl27 ribosomal protein L27 increases expression ISO fenbuconazole results in increased expression of RPL27 mRNA CTD PMID:15942997 NCBI chr10:86,375,511...86,379,210
Ensembl chr10:86,375,454...86,379,193
JBrowse link
G Rps19 ribosomal protein S19 increases expression ISO fenbuconazole results in increased expression of RPS19 mRNA CTD PMID:15942997
G Rps3a ribosomal protein S3a increases expression ISO fenbuconazole results in increased expression of RPS3A mRNA CTD PMID:15942997 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps7 ribosomal protein S7 increases expression ISO fenbuconazole results in increased expression of RPS7 mRNA CTD PMID:15942997 NCBI chr 6:45,266,200...45,271,064 JBrowse link
G Sord sorbitol dehydrogenase increases expression ISO fenbuconazole results in increased expression of SORD mRNA CTD PMID:15942997 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression ISO fenbuconazole results in decreased expression of SULT1A1 mRNA CTD PMID:15942997 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO fenbuconazole results in increased expression of TGFB3 mRNA CTD PMID:15942997 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tuba1b tubulin, alpha 1B increases expression ISO fenbuconazole results in increased expression of TUBA1B mRNA CTD PMID:15942997 NCBI chr 7:130,090,669...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Vmp1 vacuole membrane protein 1 increases expression ISO fenbuconazole results in increased expression of VMP1 mRNA CTD PMID:15942997 NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,405,452...71,505,007
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      group 19741
        pseudohalo group 3490
          cyano group 3490
            nitrile 3490
              4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile 33
                (R)-fenbuconazole + 33
                (S)-fenbuconazole + 33
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  heteroarene 16530
                                    monocyclic heteroarene 13437
                                      azole 12628
                                        triazoles 3664
                                          4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile 33
                                            (R)-fenbuconazole + 33
                                            (S)-fenbuconazole + 33
paths to the root