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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:L-cysteine derivative
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Accession:CHEBI:83824 term browser browse the term
Definition:A proteinogenic amino acid derivative resulting from the formal reaction of L-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of L-cysteine by a heteroatom.
Synonyms:related_synonym: L-cysteine derivatives


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glutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLDN4 claudin 4 multiple interactions EXP Glutathione inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] CTD PMID:23816505 NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] CTD PMID:23816505 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein] CTD PMID:23816505 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:23816505 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:23816505 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119
JBrowse link
N-acetyl-L-cysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLDN4 claudin 4 multiple interactions EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] CTD PMID:23816505 NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] CTD PMID:23816505 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein] CTD PMID:23816505 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:23816505 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:23816505 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 228
    role 228
      application 196
        food additive 33
          flour treatment agent 13
            L-cysteine 5
              L-cysteine derivative 5
                (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-(\{N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl\}amino)-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide 0
                (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-(\{N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl\}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide 0
                2'-(S-L-cysteinyl)-L-histidine 0
                2-amino-3-(cystein-S-yl)isoxazolidin-5-ylacetic acid 0
                3'-(S-L-cysteinyl)-L-tyrosine 0
                4-(S-L-cysteinyl)-L-glutamic acid 0
                L-cysteic acid 0
                L-cysteine 2-naphthylamide 0
                L-cysteine amide 0
                L-cysteine methyl disulfide 0
                L-cysteine methyl ester 0
                L-cysteine oxazolecarboxylic acid 0
                L-cysteine oxazolinecarboxylic acid 0
                L-cysteine thiazolecarboxylic acid 0
                L-cysteine-S-dioxide + 0
                L-cysteinyl ester + 0
                L-cystine + 0
                L-cystine di-2-naphthylamide 0
                L-cystine mono-2-naphthylamide 0
                L-djenkolic acid 0
                N(2)-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]-N-butyl-L-cysteinamide 0
                N(2)-[(R)-2-amino-2-(4-hydroxyphenyl)acetyl]-N-butyl-L-cysteinamide 0
                N(2)-[(R)-2-amino-2-phenylacetyl]-N-butyl-L-cysteinamide 0
                N-(L-isoaspartyl)-L-cysteine 0
                N-12-oxomyristoyl-L-cysteine residue 0
                N-12R-hydroxymyristoyl-L-cysteine residue 0
                N-[(R)-4-phosphopantothenoyl]-L-cysteine 0
                N-[(R)-pantothenoyl]-L-cysteine + 0
                N-acetyl-L-cysteine + 5
                N-acetyl-S-(2-succino)-L-cysteine 0
                N-acetylalliin 0
                N-butyl-N(2)-(2-thienylacetyl)-L-cysteinamide 0
                N-butyl-N(2)-[(2Z)-2-(2-furyl)-2-(methoxyimino)acetyl]-L-cysteinamide 0
                N-butyl-N(2)-[(R)-2-hydroxy-2-phenylacetyl]-L-cysteinamide 0
                N-carbamoyl-L-cysteine 0
                N-pyruvic acid 2-iminyl-L-cysteine 0
                S-(1,4-dihydroxynonan-3-yl)-L-cysteine 0
                S-(12-hydroxyfarnesyl)-L-cysteine residue 0
                S-(15-deoxy-Delta(12,14)-prostaglandin J2-9-yl)cysteine residue(1-) 0
                S-(5-histidyl)cysteine sulfoxide 0
                S-(6-FMN)-L-cysteine 0
                S-(8alpha-FAD)-L-cysteine 0
                S-(ADP-ribosyl)-L-cysteine + 0
                S-(diphytanylglyceryl)-L-cysteine residue 0
                S-(long-chain fatty acyl)-L-cysteine + 0
                S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + 0
                S-acetyl-L-cysteine 0
                S-adenosyl-L-cysteine 0
                S-anthraniloyl-L-cysteine + 0
                S-glycosyl-L-cysteine + 0
                S-glycyl-L-cysteine 0
                S-hydroxy-L-cysteine + 0
                S-nitroso-L-cysteine + 0
                S-octanoyl-L-cysteine 0
                S-oxy-L-cysteine + 0
                S-phycocyanobilin-L-cysteine 0
                S-phycoerythrobilin-L-cysteine 0
                S-phytochromobilin-L-cysteine 0
                S-substituted L-cysteine + 0
                S-substituted N-acetyl-L-cysteine + 0
                S-sulfanylglutathione 0
                alliin + 0
                cilastatin 0
                glutathione + 5
                glutathione S-sulfinate 0
                glutathione sulfonate 0
                grixazone A 0
                grixazone B 0
                hercynylcysteine sulfoxide 0
                meso-lanthionine 0
                palmitoyl-L-cysteine + 0
                phycourobilin-bis-L-cysteine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 228
    subatomic particle 228
      composite particle 228
        hadron 228
          baryon 228
            nucleon 228
              atomic nucleus 228
                atom 228
                  main group element atom 221
                    p-block element atom 221
                      carbon group element atom 209
                        carbon atom 208
                          organic molecular entity 208
                            organic group 155
                              organic divalent group 154
                                organodiyl group 154
                                  carbonyl group 154
                                    carbonyl compound 154
                                      carboxylic acid 115
                                        amino acid 27
                                          alpha-amino acid 11
                                            L-alpha-amino acid 8
                                              serine family amino acid 5
                                                L-cysteine 5
                                                  L-cysteine derivative 5
                                                    (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-(\{N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl\}amino)-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide 0
                                                    (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-(\{N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl\}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide 0
                                                    2'-(S-L-cysteinyl)-L-histidine 0
                                                    2-amino-3-(cystein-S-yl)isoxazolidin-5-ylacetic acid 0
                                                    3'-(S-L-cysteinyl)-L-tyrosine 0
                                                    4-(S-L-cysteinyl)-L-glutamic acid 0
                                                    L-cysteic acid 0
                                                    L-cysteine 2-naphthylamide 0
                                                    L-cysteine amide 0
                                                    L-cysteine methyl disulfide 0
                                                    L-cysteine methyl ester 0
                                                    L-cysteine oxazolecarboxylic acid 0
                                                    L-cysteine oxazolinecarboxylic acid 0
                                                    L-cysteine thiazolecarboxylic acid 0
                                                    L-cysteine-S-dioxide + 0
                                                    L-cysteinyl ester + 0
                                                    L-cystine + 0
                                                    L-cystine di-2-naphthylamide 0
                                                    L-cystine mono-2-naphthylamide 0
                                                    L-djenkolic acid 0
                                                    N(2)-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]-N-butyl-L-cysteinamide 0
                                                    N(2)-[(R)-2-amino-2-(4-hydroxyphenyl)acetyl]-N-butyl-L-cysteinamide 0
                                                    N(2)-[(R)-2-amino-2-phenylacetyl]-N-butyl-L-cysteinamide 0
                                                    N-(L-isoaspartyl)-L-cysteine 0
                                                    N-12-oxomyristoyl-L-cysteine residue 0
                                                    N-12R-hydroxymyristoyl-L-cysteine residue 0
                                                    N-[(R)-4-phosphopantothenoyl]-L-cysteine 0
                                                    N-[(R)-pantothenoyl]-L-cysteine + 0
                                                    N-acetyl-L-cysteine + 5
                                                    N-acetyl-S-(2-succino)-L-cysteine 0
                                                    N-acetylalliin 0
                                                    N-butyl-N(2)-(2-thienylacetyl)-L-cysteinamide 0
                                                    N-butyl-N(2)-[(2Z)-2-(2-furyl)-2-(methoxyimino)acetyl]-L-cysteinamide 0
                                                    N-butyl-N(2)-[(R)-2-hydroxy-2-phenylacetyl]-L-cysteinamide 0
                                                    N-carbamoyl-L-cysteine 0
                                                    N-pyruvic acid 2-iminyl-L-cysteine 0
                                                    S-(1,4-dihydroxynonan-3-yl)-L-cysteine 0
                                                    S-(12-hydroxyfarnesyl)-L-cysteine residue 0
                                                    S-(15-deoxy-Delta(12,14)-prostaglandin J2-9-yl)cysteine residue(1-) 0
                                                    S-(5-histidyl)cysteine sulfoxide 0
                                                    S-(6-FMN)-L-cysteine 0
                                                    S-(8alpha-FAD)-L-cysteine 0
                                                    S-(ADP-ribosyl)-L-cysteine + 0
                                                    S-(diphytanylglyceryl)-L-cysteine residue 0
                                                    S-(long-chain fatty acyl)-L-cysteine + 0
                                                    S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + 0
                                                    S-acetyl-L-cysteine 0
                                                    S-adenosyl-L-cysteine 0
                                                    S-anthraniloyl-L-cysteine + 0
                                                    S-glycosyl-L-cysteine + 0
                                                    S-glycyl-L-cysteine 0
                                                    S-hydroxy-L-cysteine + 0
                                                    S-nitroso-L-cysteine + 0
                                                    S-octanoyl-L-cysteine 0
                                                    S-oxy-L-cysteine + 0
                                                    S-phycocyanobilin-L-cysteine 0
                                                    S-phycoerythrobilin-L-cysteine 0
                                                    S-phytochromobilin-L-cysteine 0
                                                    S-substituted L-cysteine + 0
                                                    S-substituted N-acetyl-L-cysteine + 0
                                                    S-sulfanylglutathione 0
                                                    alliin + 0
                                                    cilastatin 0
                                                    glutathione + 5
                                                    glutathione S-sulfinate 0
                                                    glutathione sulfonate 0
                                                    grixazone A 0
                                                    grixazone B 0
                                                    hercynylcysteine sulfoxide 0
                                                    meso-lanthionine 0
                                                    palmitoyl-L-cysteine + 0
                                                    phycourobilin-bis-L-cysteine 0
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