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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:non-proteinogenic L-alpha-amino acid
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Accession:CHEBI:83822 term browser browse the term
Definition:Any L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.
Synonyms:related_synonym: non-proteinogenic L-alpha-amino acids


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(N(omega)-L-arginino)succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
decreases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
(S)-3,5-dihydroxyphenylglycine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor decreases activity ISO BDNF protein results in decreased activity of 3,5-dihydroxyphenylglycine CTD PMID:20554863 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
EXP
ISO
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of CREB1 protein]]; N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of CREB1 protein] CTD PMID:16600209 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions
affects localization
ISO
EXP
3,5-dihydroxyphenylglycine inhibits the reaction [FMR1 gene mutant form results in increased activity of MGLL]
3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA; 3,5-dihydroxyphenylglycine affects the localization of FMR1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 protein]; Ro 32-0432 inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA]; Ro 32-0432 inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 protein]
CTD PMID:15028757, PMID:20393458 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases phosphorylation
EXP 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of GRIN1 protein]]; N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of GRIN1 protein] CTD PMID:16600209 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions
increases activity
EXP 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased phosphorylation of MAP2 protein; Flufenamic Acid inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein]; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; Potassium promotes the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein]; Ruthenium Red inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; Sodium promotes the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] CTD PMID:14622174, PMID:15893642 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Grm5 glutamate metabotropic receptor 5 multiple interactions
increases activity
ISO
EXP
[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide binds to GRM5 protein] promotes the reaction [3,5-dihydroxyphenylglycine binds to and results in increased activity of GRM5 protein]
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM5 protein]; [3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide binds to GRM5 protein] promotes the reaction [3,5-dihydroxyphenylglycine binds to and results in increased activity of GRM5 protein]
CTD PMID:15608073, PMID:17179862 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Map2 microtubule-associated protein 2 increases phosphorylation
multiple interactions
EXP 3,5-dihydroxyphenylglycine results in increased phosphorylation of MAP2 protein
[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased phosphorylation of MAP2 protein; Ammonia inhibits the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of MAP2 protein]
CTD PMID:15893642 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
3,5-dihydroxyphenylglycine results in increased phosphorylation of MAPK1 protein
3,5-dihydroxyphenylglycine promotes the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of MAPK1 protein]]; N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of MAPK1 protein]
CTD PMID:16600209, PMID:30205134 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of MAPK3 protein]]; N-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide promotes the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of MAPK3 protein]
3,5-dihydroxyphenylglycine promotes the reaction [Permethrin results in increased phosphorylation of MAPK3 protein]
CTD PMID:16600209, PMID:30205134 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mgll monoglyceride lipase multiple interactions ISO 3,5-dihydroxyphenylglycine inhibits the reaction [FMR1 gene mutant form results in increased activity of MGLL] CTD PMID:20393458 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
3-(5-fluorouracil-1-yl)-L-alanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 affects response to substance ISO GRIA3 protein affects the susceptibility to 5-fluorowillardiine CTD PMID:15264227 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
5-oxo-L-proline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene multiple interactions ISO DEK protein results in decreased chemical synthesis of and results in increased uptake of Pyrrolidonecarboxylic Acid CTD PMID:28558019 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Pyrrolidonecarboxylic Acid analog CTD PMID:26820058 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
acivicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator multiple interactions ISO acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein]; acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of CFTR mRNA] CTD PMID:14766015 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions
decreases activity
ISO [acivicin results in decreased activity of GGT1 protein] which results in decreased susceptibility to Glutathione CTD PMID:15629191, PMID:19419996 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
alpha-methyl-L-dopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation
decreases activity
ISO COMT protein results in increased methylation of Methyldopa
Methyldopa results in decreased activity of COMT protein
CTD PMID:7053299, PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTA1 protein CTD PMID:8131222 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTM1 protein CTD PMID:8131222 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTP1 protein CTD PMID:8131222 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Prl prolactin increases expression
increases secretion
ISO Methyldopa results in increased expression of PRL protein
Methyldopa results in increased secretion of PRL protein
CTD PMID:1867878, PMID:7265421 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ren renin decreases activity EXP Methyldopa results in decreased activity of REN protein CTD PMID:145319 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
cilastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Cilastatin inhibits the reaction [Vancomycin results in decreased expression of and affects the localization of ABCB1 protein]; Cilastatin results in increased expression of and affects the localization of ABCB1 protein CTD PMID:28549670 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Dpep1 dipeptidase 1 decreases activity ISO Cilastatin results in decreased activity of DPEP1 protein CTD PMID:30664745 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
domoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression
increases localization
multiple interactions
ISO domoic acid results in increased expression of BAX mRNA
domoic acid results in increased localization of BAX protein
Carbachol inhibits the reaction [domoic acid results in increased localization of BAX protein]
CTD PMID:18293405, PMID:19200344 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO domoic acid affects the expression of BCL2 mRNA CTD PMID:18293405 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Carbachol inhibits the reaction [domoic acid results in increased activity of CASP3 protein] CTD PMID:19200344 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO domoic acid results in increased expression of GCLC mRNA; domoic acid results in increased expression of GCLC protein CTD PMID:23315585 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
decreases response to substance
affects response to substance
ISO domoic acid results in increased expression of GCLM mRNA; domoic acid results in increased expression of GCLM protein
[GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to 2,3-dimethoxy-1,4-naphthoquinone; [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to Hydrogen Peroxide; GCLM protein results in decreased susceptibility to domoic acid; GCLM results in decreased susceptibility to domoic acid
GCLM affects the susceptibility to domoic acid
CTD PMID:17804861, PMID:19200344, PMID:23315585 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases phosphorylation EXP domoic acid results in increased phosphorylation of GRIA1 protein CTD PMID:19564213 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Pvalb parvalbumin increases expression ISO domoic acid results in increased expression of PVALB protein CTD PMID:26797589 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Wdr35 WD repeat domain 35 increases expression
multiple interactions
EXP domoic acid results in increased expression of WDR35 mRNA; domoic acid results in increased expression of WDR35 protein
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [domoic acid results in increased expression of WDR35 protein]; Edaravone inhibits the reaction [domoic acid results in increased expression of WDR35 protein]
CTD PMID:23289926 NCBI chr 6:34,094,291...34,152,048
Ensembl chr 6:34,094,306...34,151,622
JBrowse link
kainic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Kainic Acid results in increased expression of ABCB1A mRNA; Kainic Acid results in increased expression of ABCB1A protein CTD PMID:14706787 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP Kainic Acid results in increased expression of ABCB1B mRNA; Kainic Acid results in increased expression of ABCB1B protein CTD PMID:14706787 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Kainic Acid results in increased expression of ABCG2 mRNA CTD PMID:17997037 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Aco2 aconitase 2 multiple interactions
decreases activity
EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein] CTD PMID:11520895 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acp1 acid phosphatase 1 decreases expression ISO Kainic Acid results in decreased expression of ACP1 mRNA CTD PMID:17997037 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Adk adenosine kinase increases expression ISO Kainic Acid results in increased expression of ADK mRNA CTD PMID:17997037 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adnp activity-dependent neuroprotector homeobox multiple interactions
decreases expression
EXP Enzyme Inhibitors inhibits the reaction [Kainic Acid results in decreased expression of ADNP protein]
Kainic Acid results in decreased expression of ADNP mRNA; Kainic Acid results in decreased expression of ADNP protein
CTD PMID:18375135 NCBI chr 3:164,937,188...164,964,819
Ensembl chr 3:164,937,198...164,964,702
JBrowse link
G Adra1b adrenoceptor alpha 1B increases response to substance ISO ADRA1B protein results in increased susceptibility to Kainic Acid CTD PMID:19125850 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression
multiple interactions
EXP Kainic Acid results in increased expression of AIF1 protein
NADP inhibits the reaction [Kainic Acid results in increased expression of AIF1 protein]
CTD PMID:32057834 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases localization
multiple interactions
ISO Kainic Acid results in increased localization of AIFM1 protein
Minocycline inhibits the reaction [Kainic Acid results in increased localization of AIFM1 protein]
CTD PMID:16469440 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression EXP Kainic Acid results in increased expression of ALOX5AP mRNA CTD PMID:19700661 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Kainic Acid results in increased expression of APAF1 mRNA CTD PMID:17997037 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions EXP [Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA CTD PMID:16120186 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoe apolipoprotein E decreases expression ISO Kainic Acid results in decreased expression of APOE mRNA CTD PMID:17997037 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression EXP
ISO
Kainic Acid results in increased expression of ARC mRNA; Kainic Acid results in increased expression of ARC protein CTD PMID:17632064, PMID:30557575 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein decreases expression EXP Kainic Acid results in decreased expression of ATF7IP mRNA CTD PMID:19700661 NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of ATG5 protein] CTD PMID:32057834 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G B4galt2 beta-1,4-galactosyltransferase 2 decreases expression ISO Kainic Acid results in decreased expression of B4GALT2 mRNA CTD PMID:17997037 NCBI chr 5:136,707,510...136,717,345
Ensembl chr 5:136,707,510...136,715,981
JBrowse link
G Bag3 BAG cochaperone 3 increases expression EXP Kainic Acid results in increased expression of BAG3 mRNA CTD PMID:19700661 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
Kainic Acid results in increased expression of BAX mRNA; Kainic Acid results in increased expression of BAX protein
oridonin inhibits the reaction [Kainic Acid results in increased expression of BAX mRNA]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]]
Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of BAX protein]
CTD PMID:18711747, PMID:19700661, PMID:25453207, PMID:31430510 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]
Kainic Acid results in decreased expression of BCL2 mRNA
oridonin inhibits the reaction [Kainic Acid results in decreased expression of BCL2 mRNA]
CTD PMID:25453207, PMID:31430510 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
EXP [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]
Kainic Acid results in increased expression of BDNF mRNA; Kainic Acid results in increased expression of BDNF protein
CTD PMID:1641125, PMID:9073163, PMID:11279263, PMID:16166269, PMID:17827730, PMID:19700661 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of BECN1 protein] CTD PMID:32057834 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G C1qb complement C1q B chain increases expression ISO Kainic Acid results in increased expression of C1QB mRNA CTD PMID:17997037 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C4b complement C4B (Chido blood group) increases expression ISO Kainic Acid results in increased expression of C4B mRNA CTD PMID:17997037 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Calb1 calbindin 1 decreases expression ISO Kainic Acid results in decreased expression of CALB1 mRNA CTD PMID:17997037 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO Kainic Acid results in decreased expression of CAMK4 mRNA CTD PMID:17997037 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Capns1 calpain, small subunit 1 increases expression EXP Kainic Acid results in increased expression of CAPNS1 mRNA CTD PMID:19700661 NCBI chr 1:91,058,528...91,064,880 JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Kainic Acid results in increased activity of CASP3 protein
oridonin inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of CASP3 protein]
Kainic Acid results in increased cleavage of CASP3 protein
Kainic Acid results in increased expression of CASP3 mRNA; Kainic Acid results in increased expression of CASP3 protein
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]]; Minocycline inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]; Valproic Acid inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]
CTD PMID:16469440, PMID:18711747, PMID:19700661, PMID:25453207, PMID:31430510 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions
ISO
EXP
Kainic Acid results in decreased expression of CAT mRNA; Kainic Acid results in decreased expression of CAT protein
Kainic Acid results in decreased activity of CAT protein
oridonin inhibits the reaction [Kainic Acid results in decreased activity of CAT protein]
CTD PMID:29208536, PMID:31430510 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cck cholecystokinin decreases expression EXP Kainic Acid results in decreased expression of CCK protein CTD PMID:7774662 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Kainic Acid results in increased expression of CCL2 mRNA CTD PMID:19700661 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccne1 cyclin E1 increases expression EXP Kainic Acid results in increased expression of CCNE1 protein CTD PMID:12941380 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd68 Cd68 molecule increases expression EXP Kainic Acid results in increased expression of CD68 mRNA CTD PMID:19700661 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cdc42 cell division cycle 42 increases expression EXP Kainic Acid results in increased expression of CDC42 mRNA CTD PMID:19700661 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh13 cadherin 13 increases expression ISO Kainic Acid results in increased expression of CDH13 mRNA CTD PMID:17997037 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression EXP Kainic Acid results in increased expression of CDK2 protein CTD PMID:12941380 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Kainic Acid results in increased expression of CEACAM1 mRNA CTD PMID:17997037 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Chgb chromogranin B increases expression EXP Kainic Acid results in increased expression of CHGB mRNA CTD PMID:9427505 NCBI chr 3:125,428,050...125,441,601
Ensembl chr 3:125,428,260...125,441,594
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression EXP Kainic Acid results in increased expression of CITED2 mRNA CTD PMID:19700661 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cnr1 cannabinoid receptor 1 increases expression EXP Kainic Acid results in increased expression of CNR1 mRNA CTD PMID:22079489 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 increases expression EXP Kainic Acid results in increased expression of CNRIP1 mRNA CTD PMID:22079489 NCBI chr14:100,217,547...100,247,235
Ensembl chr14:100,217,289...100,247,235
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Kainic Acid results in increased expression of COL1A1 mRNA CTD PMID:17997037 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Kainic Acid results in increased expression of CRHR1 mRNA CTD PMID:12093084 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Ctsb cathepsin B multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of CTSB protein] CTD PMID:32057834 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of CTSD protein] CTD PMID:32057834 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctss cathepsin S increases expression ISO Kainic Acid results in increased expression of CTSS mRNA; Kainic Acid results in increased expression of CTSS protein CTD PMID:17997037 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Ctsz cathepsin Z increases expression ISO Kainic Acid results in increased expression of CTSZ mRNA CTD PMID:17997037 NCBI chr 3:172,527,107...172,537,877
Ensembl chr 3:172,527,107...172,537,877
JBrowse link
G Cycs cytochrome c, somatic increases localization
multiple interactions
increases expression
ISO
EXP
Kainic Acid results in increased localization of CYCS protein
Minocycline inhibits the reaction [Kainic Acid results in increased localization of CYCS protein]
Kainic Acid results in increased expression of CYCS mRNA
CTD PMID:16469440, PMID:19700661 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Kainic Acid results in decreased expression of DGCR6 mRNA CTD PMID:17997037 NCBI chr11:87,076,205...87,081,306
Ensembl chr11:87,076,381...87,081,950
JBrowse link
G Dhx36 DEAH-box helicase 36 increases expression ISO Kainic Acid results in increased expression of DHX36 mRNA CTD PMID:17997037 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression EXP Kainic Acid results in increased expression of DIABLO mRNA CTD PMID:19700661 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Drd2 dopamine receptor D2 decreases response to substance ISO DRD2 protein results in decreased susceptibility to Kainic Acid CTD PMID:11860278 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Egr1 early growth response 1 decreases expression
affects expression
ISO
EXP
Kainic Acid results in decreased expression of EGR1 mRNA
Kainic Acid affects the expression of EGR1 mRNA
CTD PMID:17997037, PMID:19700661 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 increases expression EXP Kainic Acid results in increased expression of EIF4A3 protein CTD PMID:17632064 NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
JBrowse link
G Emc3 ER membrane protein complex subunit 3 decreases expression ISO Kainic Acid results in decreased expression of EMC3 mRNA CTD PMID:17997037 NCBI chr 4:145,471,466...145,487,375
Ensembl chr 4:145,471,454...145,487,426
JBrowse link
G En2 engrailed homeobox 2 affects response to substance
decreases expression
ISO EN2 protein affects the susceptibility to Kainic Acid
Kainic Acid results in decreased expression of EN2 mRNA
CTD PMID:19186208 NCBI chr 4:438,668...444,508
Ensembl chr 4:438,668...444,501
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression ISO Kainic Acid results in decreased expression of ENC1 mRNA CTD PMID:17997037 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]; EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of CASP3 protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]] CTD PMID:18711747 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor multiple interactions
decreases expression
ISO
EXP
EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]] CTD PMID:18711747 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression ISO Kainic Acid results in decreased expression of ETFB mRNA CTD PMID:17997037 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 decreases expression ISO Kainic Acid results in decreased expression of FBXW5 mRNA CTD PMID:17997037 NCBI chr 3:2,726,705...2,731,213
Ensembl chr 3:2,727,254...2,731,212
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression EXP Kainic Acid results in increased expression of FGF2 mRNA CTD PMID:7649223 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf5 fibroblast growth factor 5 increases expression EXP Kainic Acid results in increased expression of FGF5 mRNA CTD PMID:7649223 NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression EXP Kainic Acid results in increased expression of FGFR1 mRNA CTD PMID:7649223 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO
EXP
10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone inhibits the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; [Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of FOS protein; Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of FOS protein]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]
Kainic Acid results in increased expression of FOS mRNA; Kainic Acid results in increased expression of FOS protein
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; [Phenytoin co-treated with Drugs, Chinese Herbal] inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; Diazepam inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of FOS protein]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]
Kainic Acid results in decreased expression of FOS mRNA
CTD PMID:7655348, PMID:7887109, PMID:8417141, PMID:8758711, PMID:15723099, PMID:16686654, PMID:17827730, PMID:17997037, PMID:26348896 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Kainic Acid results in increased expression of FOSL2 mRNA CTD PMID:19700661 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 decreases expression ISO Kainic Acid results in decreased expression of FXYD1 mRNA CTD PMID:17997037 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression
multiple interactions
ISO Kainic Acid results in increased expression of GABRB1 mRNA
Quercetin inhibits the reaction [Kainic Acid results in increased expression of GABRB1 mRNA]
CTD PMID:27386150 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 multiple interactions
increases expression
ISO Quercetin inhibits the reaction [Kainic Acid results in increased expression of GABRB3 mRNA] CTD PMID:27386150 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression EXP Kainic Acid results in increased expression of GAD1 mRNA CTD PMID:16797850 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 increases expression EXP Kainic Acid results in increased expression of GAD2 mRNA CTD PMID:16797850 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Kainic Acid results in increased expression of GADD45A mRNA; Kainic Acid results in increased expression of GADD45A protein CTD PMID:20955365 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO Kainic Acid results in decreased expression of GADD45B mRNA CTD PMID:17997037 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression ISO Kainic Acid results in decreased expression of GADD45G mRNA CTD PMID:17997037 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gap43 growth associated protein 43 multiple interactions
increases expression
EXP Dizocilpine Maleate inhibits the reaction [Kainic Acid results in increased expression of GAP43 mRNA]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of GAP43 mRNA] CTD PMID:8774942 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Kainic Acid results in increased expression of GCNT2 mRNA CTD PMID:17997037 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions
EXP
ISO
Kainic Acid results in increased expression of GFAP mRNA; Kainic Acid results in increased expression of GFAP protein
NADP inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]
PTGS2 affects the reaction [Kainic Acid results in increased expression of GFAP mRNA]
CTD PMID:17997037, PMID:18711747, PMID:19700661, PMID:21589914, PMID:22790971, PMID:32057834 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
decreases expression
EXP oridonin inhibits the reaction [Kainic Acid results in decreased expression of GLUL mRNA] CTD PMID:31430510 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO Kainic Acid results in decreased expression of GPX1 protein CTD PMID:29208536 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions
decreases expression
EXP
ISO
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of GRIA1 protein]; Kainic Acid binds to and results in increased activity of GRIA1 protein; Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA1 protein]
Kainic Acid results in decreased expression of GRIA1 mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]
Kainic Acid results in decreased expression of GRIA1 mRNA; Kainic Acid results in decreased expression of GRIA1 protein
CTD PMID:7529610, PMID:11812690, PMID:17585341, PMID:21589914 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions
increases methylation
decreases expression
affects response to substance
EXP
ISO
Kainic Acid binds to and results in increased activity of GRIA2 protein; Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA2 protein]
Kainic Acid results in increased methylation of GRIA2 gene
Kainic Acid results in decreased expression of GRIA2 mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA2 mRNA]; RG108 inhibits the reaction [Kainic Acid results in increased methylation of GRIA2 gene]
GRIA2 protein affects the susceptibility to Kainic Acid
CTD PMID:7529610, PMID:10551584, PMID:11812690, PMID:21589914, PMID:24098468 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression
multiple interactions
increases expression
EXP
ISO
Kainic Acid results in decreased expression of GRIA3 mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA3 mRNA]
Kainic Acid results in increased expression of GRIA3 mRNA
CTD PMID:7529610, PMID:21589914 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIA4 mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA4 mRNA]
CTD PMID:21589914 NCBI chr 8:1,548,145...2,045,874
Ensembl chr 8:1,548,146...2,045,817
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 decreases expression
increases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIK1 mRNA
Kainic Acid results in increased expression of GRIK1 mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA]
CTD PMID:21589914, PMID:29208536 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression
multiple interactions
ISO Kainic Acid results in increased expression of GRIK2 mRNA
[Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK2 mRNA
CTD PMID:17997037, PMID:21589914, PMID:29208536 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIK3 mRNA
[Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK3 mRNA
CTD PMID:21589914 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 multiple interactions
decreases expression
ISO [Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK4 mRNA
Kainic Acid results in decreased expression of GRIK4 mRNA
CTD PMID:21589914 NCBI chr 8:46,804,134...47,237,546
Ensembl chr 8:46,806,147...47,094,352
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions
decreases expression
ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA] CTD PMID:21589914 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
affects expression
decreases expression
ISO
EXP
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN1 mRNA]
Kainic Acid affects the expression of GRIN1
CTD PMID:21589914, PMID:23159308 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN2A mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2A mRNA]
CTD PMID:21589914 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
decreases expression
ISO celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2B mRNA] CTD PMID:21589914 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN2C mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA]
CTD PMID:21589914 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN2D mRNA
Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA]
CTD PMID:21589914 NCBI chr 1:101,819,068...101,859,146
Ensembl chr 1:101,820,461...101,856,881
JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A multiple interactions
decreases expression
ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA] CTD PMID:21589914 NCBI chr 5:64,928,620...65,073,012
Ensembl chr 5:64,928,620...65,073,012
JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B decreases expression
multiple interactions
ISO Kainic Acid results in decreased expression of GRIN3B mRNA
celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3B mRNA]
CTD PMID:21589914 NCBI chr 7:12,764,993...12,771,310
Ensembl chr 7:12,764,993...12,771,310
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity
decreases phosphorylation
multiple interactions
ISO Kainic Acid results in decreased activity of GSK3B protein
Kainic Acid results in decreased phosphorylation of GSK3B protein
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]
CTD PMID:18619545, PMID:25453207 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP oridonin inhibits the reaction [Kainic Acid results in decreased activity of GSR protein] CTD PMID:31430510 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions
decreases expression
EXP Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]; REST mutant form inhibits the reaction [Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 mRNA]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 protein]
Kainic Acid results in decreased expression of HCN1 mRNA; Kainic Acid results in decreased expression of HCN1 protein
CTD PMID:21905079 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Kainic Acid results in increased expression of HMOX1 mRNA CTD PMID:7655348 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Kainic Acid results in increased expression of HOMER1 mRNA CTD PMID:19700661 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Hpca hippocalcin decreases response to substance ISO HPCA protein results in decreased susceptibility to Kainic Acid CTD PMID:15607944 NCBI chr 5:147,295,124...147,305,757
Ensembl chr 5:147,294,820...147,303,346
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Kainic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:17997037 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein; Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]; GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein] CTD PMID:16686654 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Kainic Acid results in decreased expression of IDI1 mRNA CTD PMID:17997037 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Il10 interleukin 10 decreases expression EXP Kainic Acid results in decreased expression of IL10 protein CTD PMID:15591643 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A affects response to substance ISO IL12A protein affects the susceptibility to Kainic Acid CTD PMID:15474355 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il1b interleukin 1 beta increases secretion
increases expression
multiple interactions
EXP
ISO
Kainic Acid results in increased secretion of IL1B protein
Kainic Acid results in increased expression of IL1B mRNA; Kainic Acid results in increased expression of IL1B protein
PTGS2 affects the reaction [Kainic Acid results in increased expression of IL1B mRNA]
Minocycline inhibits the reaction [Kainic Acid results in increased secretion of IL1B protein]; oridonin inhibits the reaction [Kainic Acid results in increased expression of IL1B protein]
CTD PMID:7655348, PMID:11306611, PMID:21589914, PMID:31430510 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases response to substance
multiple interactions
increases expression
ISO
EXP
IL6 protein results in increased susceptibility to Kainic Acid
oridonin inhibits the reaction [Kainic Acid results in increased expression of IL6 protein]
Kainic Acid results in increased expression of IL6 mRNA
PTGS2 affects the reaction [Kainic Acid results in increased expression of IL6 mRNA]
CTD PMID:12836160, PMID:21589914, PMID:31430510 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
ISO Kainic Acid results in increased expression of ITGAM mRNA
PTGS2 affects the reaction [Kainic Acid results in increased expression of ITGAM mRNA]
CTD PMID:21589914 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Jagn1 jagunal homolog 1 decreases expression ISO Kainic Acid results in decreased expression of JAGN1 mRNA CTD PMID:17997037 NCBI chr 4:145,399,885...145,404,605
Ensembl chr 4:145,399,913...145,404,617
JBrowse link
G Jak2 Janus kinase 2 multiple interactions
decreases expression
ISO
EXP
EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]] CTD PMID:18711747 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; Diazepam inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of JUN protein]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of JUN protein]
Kainic Acid results in increased expression of JUN mRNA; Kainic Acid results in increased expression of JUN protein
CTD PMID:8417141, PMID:15723099, PMID:17827730 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
ISO
EXP
Kainic Acid results in decreased expression of JUNB mRNA
Kainic Acid results in increased expression of JUNB mRNA
CTD PMID:17997037, PMID:19700661 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kalrn kalirin, RhoGEF kinase increases expression EXP Kainic Acid results in increased expression of KALRN mRNA CTD PMID:19700661 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 increases expression EXP Kainic Acid results in increased expression of KCNC2 protein CTD PMID:7643197 NCBI chr 7:54,978,453...55,159,362
Ensembl chr 7:54,980,120...55,159,351
JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 decreases expression EXP Kainic Acid results in decreased expression of KCNC4 protein CTD PMID:21905079 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 increases response to substance ISO KCNQ2 protein mutant form results in increased susceptibility to Kainic Acid CTD PMID:26910900 NCBI chr 3:176,585,897...176,645,029
Ensembl chr 3:176,589,906...176,644,951
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Kainic Acid results in decreased expression of KIF20A mRNA CTD PMID:17997037 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression ISO Kainic Acid results in decreased expression of KLF10 mRNA CTD PMID:17997037 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Kng2 kininogen 2 multiple interactions EXP Kainic Acid promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form] CTD PMID:7807204 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP Kainic Acid results in increased expression of KRAS mRNA CTD PMID:19700661 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lep leptin decreases response to substance ISO LEP protein results in decreased susceptibility to Kainic Acid CTD PMID:17993459 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lmo1 LIM domain only 1 decreases expression ISO Kainic Acid results in decreased expression of LMO1 mRNA CTD PMID:17997037 NCBI chr 1:173,728,183...173,764,288
Ensembl chr 1:173,728,184...173,764,250
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of MAP1LC3B protein modified form] CTD PMID:32057834 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
increases expression
ISO PTGS2 affects the reaction [Kainic Acid results in increased expression of MAP2 mRNA] CTD PMID:21589914 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Kainic Acid results in decreased expression of MAP3K5 mRNA CTD PMID:17997037 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression ISO Kainic Acid results in increased expression of MAPK3 mRNA CTD PMID:17997037 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mast3 microtubule associated serine/threonine kinase 3 decreases expression ISO Kainic Acid results in decreased expression of MAST3 mRNA CTD PMID:17997037 NCBI chr16:20,387,330...20,414,767
Ensembl chr16:20,395,845...20,414,767
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity
multiple interactions
ISO Kainic Acid results in increased activity of MMP9 protein
MMP9 protein affects the reaction [Kainic Acid results in decreased expression of NCAM1 protein modified form]
CTD PMID:30772382 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component affects response to substance ISO MPDZ protein affects the susceptibility to Kainic Acid CTD PMID:14960011 NCBI chr 5:99,413,184...99,566,356
Ensembl chr 5:99,413,187...99,566,318
JBrowse link
G Mpeg1 macrophage expressed 1 increases expression ISO Kainic Acid results in increased expression of MPEG1 mRNA CTD PMID:17997037 NCBI chr 1:228,724,559...228,729,054
Ensembl chr 1:228,724,900...228,727,160
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO Kainic Acid results in decreased expression of MSMO1 mRNA CTD PMID:17997037 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Mt1 metallothionein 1 decreases response to substance
increases expression
ISO
EXP
MT1 protein results in decreased susceptibility to Kainic Acid
Kainic Acid results in increased expression of MT1A mRNA
CTD PMID:7655348, PMID:10947810 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A decreases response to substance ISO MT2 protein results in decreased susceptibility to Kainic Acid CTD PMID:10947810 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Myo5b myosin Vb decreases expression ISO Kainic Acid results in decreased expression of MYO5B mRNA CTD PMID:17997037 NCBI chr18:70,426,865...70,729,985
Ensembl chr18:70,427,007...70,729,030
JBrowse link
G Myo9a myosin IXA increases expression ISO Kainic Acid results in increased expression of MYO9A mRNA CTD PMID:17997037 NCBI chr 8:64,573,248...64,777,607
Ensembl chr 8:64,573,358...64,777,543
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 increases expression EXP
ISO
Kainic Acid results in increased expression of NAIP mRNA; Kainic Acid results in increased expression of NAIP protein CTD PMID:12547647, PMID:15046874 NCBI chr 2:30,377,505...30,418,578 JBrowse link
G Ncam1 neural cell adhesion molecule 1 decreases expression
multiple interactions
EXP
ISO
Kainic Acid results in decreased expression of NCAM1 mRNA
MMP9 protein affects the reaction [Kainic Acid results in decreased expression of NCAM1 protein modified form]
CTD PMID:19700661, PMID:30772382 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization ISO Kainic Acid affects the localization of NFE2L2 protein CTD PMID:18619545 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression
decreases expression
EXP 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of NOS1 protein]
Kainic Acid results in increased expression of NOS1 mRNA; Kainic Acid results in increased expression of NOS1 protein
CTD PMID:17585341, PMID:18375135 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Kainic Acid results in increased expression of NOS2 mRNA
Kainic Acid results in increased expression of NOS2 mRNA; Kainic Acid results in increased expression of NOS2 protein
PTGS2 affects the reaction [Kainic Acid results in increased expression of NOS2 mRNA]
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]
CTD PMID:17827730, PMID:18375135, PMID:21589914 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy neuropeptide Y decreases response to substance
multiple interactions
increases expression
ISO
EXP
NPY protein results in decreased susceptibility to Kainic Acid
Thiopental inhibits the reaction [Kainic Acid results in increased expression of NPY mRNA]
CTD PMID:9427505, PMID:15451008 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression
increases expression
ISO
EXP
Kainic Acid results in decreased expression of NR4A1 mRNA
Kainic Acid results in increased expression of NR4A1 mRNA
CTD PMID:17997037, PMID:19700661 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression EXP
ISO
Kainic Acid results in increased expression of NR4A2 mRNA
Kainic Acid results in increased expression of NR4A2 protein
CTD PMID:19700661, PMID:24813937 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Kainic Acid results in increased expression of NR4A3 mRNA CTD PMID:19700661 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nrp2 neuropilin 2 affects response to substance ISO NRP2 protein affects the susceptibility to Kainic Acid CTD PMID:18657176 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087
JBrowse link
G Ntn1 netrin 1 increases expression EXP Kainic Acid results in increased expression of NTN1 mRNA CTD PMID:19700661 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression EXP Kainic Acid results in increased expression of NTRK2 mRNA CTD PMID:19700661 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Nudcd2 NudC domain containing 2 increases expression ISO Kainic Acid results in increased expression of NUDCD2 mRNA CTD PMID:17997037 NCBI chr10:25,890,943...25,896,432
Ensembl chr10:25,890,943...25,896,432
JBrowse link
G Nudt4 nudix hydrolase 4 increases expression ISO Kainic Acid results in increased expression of NUDT4 mRNA CTD PMID:17997037 NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141
JBrowse link
G Otx2 orthodenticle homeobox 2 decreases expression EXP Kainic Acid results in decreased expression of OTX2 mRNA CTD PMID:19700661 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691
JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 decreases expression EXP Kainic Acid results in decreased expression of PAK3 mRNA CTD PMID:19700661 NCBI chr  X:114,784,452...115,042,683
Ensembl chr  X:114,929,029...115,036,669
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity EXP Kainic Acid results in increased activity of PARP1 protein CTD PMID:28704930 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdyn prodynorphin multiple interactions
increases expression
EXP Diazepam inhibits the reaction [Kainic Acid results in increased expression of PDYN mRNA]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of PDYN mRNA]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of PDYN mRNA] CTD PMID:8417141 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
JBrowse link
G Penk proenkephalin multiple interactions
increases expression
EXP Diazepam inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]; Pentobarbital inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]; Thiopental inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]; Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA] CTD PMID:8417141, PMID:9427505 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pick1 protein interacting with PRKCA 1 decreases expression ISO Kainic Acid results in decreased expression of PICK1 mRNA CTD PMID:17997037 NCBI chr 7:120,465,472...120,484,824
Ensembl chr 7:120,465,130...120,484,840
JBrowse link
G Pkp2 plakophilin 2 decreases expression ISO Kainic Acid results in decreased expression of PKP2 mRNA CTD PMID:17997037 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 decreases expression ISO Kainic Acid results in decreased expression of PLOD3 mRNA CTD PMID:17997037 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
G Ppif peptidylprolyl isomerase F increases response to substance ISO PPIF results in increased susceptibility to Kainic Acid CTD PMID:21378209 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B increases expression EXP Kainic Acid results in increased expression of PPP1R9B protein CTD PMID:17443789 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases response to substance
increases expression
EXP
ISO
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; oridonin inhibits the reaction [Kainic Acid results in increased expression of PTGS2 protein]
[PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Dinoprost; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Dinoprostone; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Prostaglandin D2; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Thromboxane B2; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of GFAP mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of IL1B mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of IL6 mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of ITGAM mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of MAP2 mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of RELA mRNA]; PTGS2 affects the reaction [Kainic Acid results in increased expression of TNF mRNA]
Kainic Acid results in increased expression of PTGS2; Kainic Acid results in increased expression of PTGS2 mRNA; Kainic Acid results in increased expression of PTGS2 protein
CTD PMID:11168565, PMID:12618123, PMID:17827730, PMID:18834901, PMID:19700661, PMID:21589914, PMID:31430510 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Qk quaking increases expression ISO Kainic Acid results in increased expression of QK mRNA CTD PMID:17997037 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Kainic Acid results in increased expression of RAC1 mRNA CTD PMID:19700661 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein increases expression EXP Kainic Acid results in increased expression of RAD23A mRNA CTD PMID:19700661 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rasd1 ras related dexamethasone induced 1 decreases expression ISO Kainic Acid results in decreased expression of RASD1 mRNA CTD PMID:17997037 NCBI chr10:46,330,361...46,339,326
Ensembl chr10:46,330,368...46,332,172
JBrowse link
G Rbfox1 RNA binding fox-1 homolog 1 increases response to substance ISO RBFOX1 gene mutant form results in increased susceptibility to Kainic Acid CTD PMID:21623373 NCBI chr10:8,312,961...10,437,778
Ensembl chr10:8,312,961...8,654,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO PTGS2 affects the reaction [Kainic Acid results in increased expression of RELA mRNA] CTD PMID:21589914 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rest RE1-silencing transcription factor increases expression
multiple interactions
EXP Kainic Acid results in increased expression of REST protein
Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]; REST mutant form inhibits the reaction [Kainic Acid promotes the reaction [REST protein binds to HCN1 intron]]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 mRNA]; REST mutant form inhibits the reaction [Kainic Acid results in decreased expression of HCN1 protein]
CTD PMID:21905079 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression ISO Kainic Acid results in decreased expression of RGS16 mRNA CTD PMID:17997037 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rhoa ras homolog family member A increases expression EXP Kainic Acid results in increased expression of RHOA mRNA CTD PMID:19700661 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 decreases expression ISO Kainic Acid results in decreased expression of S1PR1 mRNA CTD PMID:17997037 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Sap30l SAP30-like decreases expression ISO Kainic Acid results in decreased expression of SAP30L mRNA CTD PMID:17997037 NCBI chr10:43,224,151...43,231,864
Ensembl chr10:43,224,269...43,231,611
JBrowse link
G Sema4d semaphorin 4D increases expression EXP Kainic Acid results in increased expression of SEMA4D mRNA CTD PMID:19700661 NCBI chr17:13,516,276...13,538,513
Ensembl chr17:13,488,376...13,553,974
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases expression
ISO Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]; Mecamylamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]; Phentolamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression ISO Kainic Acid results in increased expression of SFPQ mRNA CTD PMID:17997037 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 multiple interactions EXP SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]]; SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]] CTD PMID:15723099 NCBI chr 5:58,121,824...58,124,687
Ensembl chr 5:58,121,786...58,124,681
JBrowse link
G Sirt1 sirtuin 1 decreases expression
increases expression
ISO
EXP
Kainic Acid results in decreased expression of SIRT1 protein
Kainic Acid results in increased expression of SIRT1 protein
CTD PMID:18538940 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression EXP Kainic Acid results in increased expression of SLC11A2 CTD PMID:16552559 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression ISO Kainic Acid results in decreased expression of SLC1A1 mRNA CTD PMID:17997037 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
increases expression
ISO
EXP
[Kainic Acid co-treated with zinc chloride] results in decreased expression of SLC1A2 protein
Ceftriaxone promotes the reaction [Kainic Acid results in increased expression of SLC1A2 protein]
CTD PMID:19061913, PMID:28257918 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Kainic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc6a2 solute carrier family 6 member 2 increases response to substance ISO SLC6A2 protein results in increased susceptibility to Kainic Acid CTD PMID:15911120 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slc8a3 solute carrier family 8 member A3 multiple interactions
increases expression
increases cleavage
EXP 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in increased cleavage of SLC8A3 protein]
Kainic Acid results in increased expression of SLC8A3 protein
CTD PMID:17585341, PMID:20928830 NCBI chr 6:104,889,500...105,099,408
Ensembl chr 6:104,891,376...105,097,054
JBrowse link
G Snrk SNF related kinase decreases expression ISO Kainic Acid results in decreased expression of SNRK mRNA CTD PMID:17997037 NCBI chr 8:130,749,806...130,805,225
Ensembl chr 8:130,749,838...130,803,597
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO Kainic Acid results in decreased expression of SOD1 protein CTD PMID:29208536 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
increases expression
EXP
ISO
Kainic Acid results in decreased expression of SOD2 protein
Kainic Acid results in decreased expression of SOD2 mRNA; Kainic Acid results in decreased expression of SOD2 protein
Kainic Acid results in increased expression of SOD2 protein
CTD PMID:10686417, PMID:29208536 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression EXP Kainic Acid results in increased expression of SPTAN1 protein modified form CTD PMID:22790971 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Sqstm1 sequestosome 1 decreases expression
multiple interactions
EXP Kainic Acid results in decreased expression of SQSTM1 protein
NADP inhibits the reaction [Kainic Acid results in decreased expression of SQSTM1 protein]
CTD PMID:32057834 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Sst somatostatin decreases expression ISO Kainic Acid results in decreased expression of SST mRNA CTD PMID:17997037 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression EXP Kainic Acid results in decreased expression of TAC1 protein CTD PMID:6205719 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase decreases expression
multiple interactions
EXP Kainic Acid results in decreased expression of TIGAR protein
NADP inhibits the reaction [Kainic Acid results in decreased expression of TIGAR protein]
CTD PMID:32057834 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
PTGS2 affects the reaction [Kainic Acid results in increased expression of TNF mRNA]; TNF protein promotes the reaction [Kainic Acid results in increased uptake of Cobalt]
oridonin inhibits the reaction [Kainic Acid results in increased expression of TNF protein]
Kainic Acid results in increased expression of TNF mRNA; Kainic Acid results in increased expression of TNF protein
CTD PMID:15869941, PMID:19700661, PMID:21589914, PMID:31430510 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Kainic Acid results in increased expression of TP53 protein CTD PMID:20955365 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trh thyrotropin releasing hormone decreases expression
increases expression
EXP Kainic Acid results in decreased expression of TRH mRNA
Kainic Acid results in increased expression of TRH mRNA
CTD PMID:10443546 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Trhr thyrotropin releasing hormone receptor decreases expression EXP Kainic Acid results in decreased expression of TRHR protein CTD PMID:10443546 NCBI chr 7:83,113,641...83,153,520
Ensembl chr 7:83,113,672...83,153,519
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp increases expression ISO Kainic Acid results in increased expression of TYROBP mRNA CTD PMID:17997037 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression EXP Kainic Acid results in increased expression of UCHL1 protein CTD PMID:22790971 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Uhmk1 U2AF homology motif kinase 1 decreases expression ISO Kainic Acid results in decreased expression of UHMK1 mRNA CTD PMID:17997037 NCBI chr13:88,521,625...88,536,728
Ensembl chr13:88,521,625...88,536,728
JBrowse link
G Uri1 URI1, prefoldin-like chaperone increases expression ISO Kainic Acid results in increased expression of URI1 mRNA CTD PMID:17997037 NCBI chr 1:94,346,513...94,404,362
Ensembl chr 1:94,346,514...94,404,211
JBrowse link
G Utp3 UTP3, small subunit processome component decreases expression ISO Kainic Acid results in decreased expression of UTP3 mRNA CTD PMID:17997037 NCBI chr14:21,153,998...21,155,652
Ensembl chr14:21,154,000...21,155,652
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 decreases expression EXP Kainic Acid results in decreased expression of VAMP7 mRNA CTD PMID:19700661 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Kainic Acid results in decreased expression of VEGFA mRNA CTD PMID:17997037 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein increases expression ISO Kainic Acid results in increased expression of WFS1 mRNA CTD PMID:17997037 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor increases expression EXP Kainic Acid results in increased expression of XPA mRNA CTD PMID:19700661 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
G Zcchc7 zinc finger CCHC-type containing 7 increases expression ISO Kainic Acid results in increased expression of ZCCHC7 mRNA CTD PMID:17997037 NCBI chr 5:60,250,546...60,430,119
Ensembl chr 5:60,250,546...60,429,708
JBrowse link
L-cystine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kyat1 kynurenine aminotransferase 1 increases amination ISO KYAT1 protein results in increased amination of Cystine CTD PMID:22093698 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Cystine affects the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein] CTD PMID:19850060 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Cystine affects the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein] CTD PMID:19850060 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases uptake
multiple interactions
ISO SLC3A1 protein results in increased uptake of Cystine
[SLC3A1 protein co-treated with SLC7A9 protein] results in increased uptake of Cystine
CTD PMID:14978168, PMID:18845132 NCBI chr 6:8,284,937...8,318,649
Ensembl chr 6:8,284,878...8,318,674
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [SLC3A2 protein co-treated with SLC7A11 protein] results in increased uptake of Cystine; Sulfasalazine inhibits the reaction [[SLC3A2 protein co-treated with SLC7A11 protein] results in increased uptake of Cystine]
[[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide; [[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione; [Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine
CTD PMID:19576933, PMID:22216172 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [SLC3A2 protein co-treated with SLC7A11 protein] results in increased uptake of Cystine; Sulfasalazine inhibits the reaction [[SLC3A2 protein co-treated with SLC7A11 protein] results in increased uptake of Cystine]
[[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide; [[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione; [Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine
CTD PMID:19576933, PMID:22216172 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a9 solute carrier family 7 member 9 multiple interactions ISO [SLC3A1 protein co-treated with SLC7A9 protein] results in increased uptake of Cystine CTD PMID:14978168 NCBI chr 1:91,709,034...91,738,492
Ensembl chr 1:91,716,383...91,738,494
JBrowse link
L-mimosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arnt aryl hydrocarbon receptor nuclear translocator increases activity EXP Mimosine results in increased activity of ARNT protein CTD PMID:10559391 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atf1 activating transcription factor 1 increases activity EXP Mimosine results in increased activity of ATF1 protein CTD PMID:10559391 NCBI chr 7:141,882,261...141,924,790
Ensembl chr 7:141,882,251...141,924,788
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO Mimosine affects the expression of BCL2 protein CTD PMID:18058236 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Mimosine results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:18058236 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Mimosine results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:18058236 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Mimosine results in decreased activity of TNF protein] CTD PMID:15550384 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Mimosine results in decreased expression of CCND1 CTD PMID:10530763, PMID:10995875 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Mimosine results in increased expression of CDKN1A CTD PMID:10530763, PMID:10995875 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Mimosine results in increased expression of CDKN1B CTD PMID:10530763 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity EXP Mimosine results in increased activity of CREB1 protein CTD PMID:10559391 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression EXP
ISO
Mimosine results in increased expression of ECE1 mRNA; Mimosine results in increased expression of ECE1 protein CTD PMID:25469848 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 increases expression ISO
EXP
Mimosine results in increased expression of EDN1 mRNA; Mimosine results in increased expression of EDN1 protein CTD PMID:25469848 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases activity
increases expression
EXP
ISO
Mimosine results in increased activity of HIF1A protein
Mimosine results in increased expression of HIF1A protein
CTD PMID:10559391, PMID:24349381, PMID:25469848 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP
ISO
Mimosine results in decreased expression of LHCGR mRNA CTD PMID:19293332 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Nmbr neuromedin B receptor increases expression ISO Mimosine results in increased expression of NMBR protein CTD PMID:24349381 NCBI chr 1:8,933,744...8,945,850
Ensembl chr 1:8,933,831...8,944,987
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO
EXP
Mimosine results in increased expression of SLC2A1 mRNA CTD PMID:25469848 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation EXP Mimosine results in increased phosphorylation of STAT3 protein CTD PMID:25469848 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases activity
ISO
EXP
Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; ferrous sulfate inhibits the reaction [Mimosine results in decreased activity of TNF protein]
Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; CAT protein inhibits the reaction [Mimosine results in decreased activity of TNF protein]
CTD PMID:15550384 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions
increases cleavage
ISO Acetylcysteine inhibits the reaction [Mimosine results in increased cleavage of TNFRSF1A protein] CTD PMID:15550384 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
L-proline betaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein] CTD PMID:32417162 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS5 protein] CTD PMID:32417162 NCBI chr11:25,411,174...25,456,639
Ensembl chr11:25,410,975...25,456,836
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; stachydrine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS5 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:32417162 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] CTD PMID:32417162 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein] CTD PMID:32417162 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:32417162 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein] CTD PMID:32417162 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:32417162 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:32417162 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein] CTD PMID:32417162 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:32417162 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
leukotriene E4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene E4]; zileuton inhibits the reaction [ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene E4]]
[zileuton results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene E4
CTD PMID:8621850, PMID:10764316, PMID:12794006 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 affects binding
multiple interactions
ISO Leukotriene E4 binds to CYSLTR1 protein
[Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein; montelukast inhibits the reaction [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein]; zafirlukast inhibits the reaction [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein]
Leukotriene E4 inhibits the reaction [Leukotriene D4 binds to CYSLTR1 protein]
CTD PMID:8384568, PMID:9620942, PMID:10462554, PMID:11705452, PMID:12853847 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 multiple interactions
increases activity
ISO [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein CTD PMID:10851239, PMID:11093801 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203
JBrowse link
G Gpr17 G protein-coupled receptor 17 increases activity ISO Leukotriene E4 results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Il13 interleukin 13 increases abundance EXP IL13 protein results in increased abundance of Leukotriene E4 CTD PMID:12654629 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Leukotriene E4 results in decreased activity of MGST1 protein CTD PMID:9890956 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression EXP Leukotriene E4 results in increased expression of MUC5AC protein CTD PMID:12654629 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased abundance of Leukotriene E4] CTD PMID:25432964 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
melphalan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects export ISO ABCC1 protein affects the export of Melphalan analog CTD PMID:11115505 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abhd17c abhydrolase domain containing 17C, depalmitoylase decreases expression ISO Melphalan results in decreased expression of ABHD17C mRNA CTD PMID:22363485 NCBI chr 1:146,248,505...146,289,465
Ensembl chr 1:146,248,503...146,289,465
JBrowse link
G Abraxas1 abraxas 1, BRCA1 A complex subunit decreases expression ISO Melphalan results in decreased expression of ABRAXAS1 mRNA CTD PMID:22363485 NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003
JBrowse link
G Abt1 activator of basal transcription 1 increases expression ISO Melphalan results in increased expression of ABT1 mRNA CTD PMID:22363485 NCBI chr17:43,946,118...43,948,224
Ensembl chr17:43,946,130...43,948,223
JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Melphalan results in increased expression of ACKR3 mRNA CTD PMID:22363485 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Acvr1c activin A receptor type 1C decreases expression ISO Melphalan results in decreased expression of ACVR1C mRNA CTD PMID:22363485 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO Melphalan results in decreased expression of AHRR mRNA CTD PMID:22363485 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Alad aminolevulinate dehydratase decreases activity ISO Melphalan results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Ammecr1l AMMECR1 like increases expression ISO Melphalan results in increased expression of AMMECR1L mRNA CTD PMID:22363485 NCBI chr18:24,539,530...24,563,576
Ensembl chr18:24,540,659...24,563,576
JBrowse link
G Ankar ankyrin and armadillo repeat containing decreases expression ISO Melphalan results in decreased expression of ANKAR mRNA CTD PMID:22363485 NCBI chr 9:53,011,561...53,086,178
Ensembl chr 9:53,013,413...53,084,010
JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO Melphalan results in increased expression of ANKRD10 mRNA CTD PMID:22363485 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Ankrd28 ankyrin repeat domain 28 decreases expression ISO Melphalan results in decreased expression of ANKRD28 mRNA CTD PMID:22363485 NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
JBrowse link
G Ankrd34a ankyrin repeat domain 34A decreases expression ISO Melphalan results in decreased expression of ANKRD34A mRNA CTD PMID:22363485 NCBI chr 2:198,720,277...198,725,155
Ensembl chr 2:198,721,724...198,725,154
JBrowse link
G Ar androgen receptor decreases expression ISO Melphalan results in decreased expression of AR mRNA CTD PMID:22363485 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgap12 Rho GTPase activating protein 12 decreases expression ISO Melphalan results in decreased expression of ARHGAP12 mRNA CTD PMID:22363485 NCBI chr17:54,280,815...54,394,716
Ensembl chr17:54,280,851...54,394,634
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Melphalan results in decreased expression of ARHGAP18 mRNA CTD PMID:22363485 NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
JBrowse link
G Arhgap20 Rho GTPase activating protein 20 decreases expression ISO Melphalan results in decreased expression of ARHGAP20 mRNA CTD PMID:22363485 NCBI chr 8:56,179,581...56,264,343
Ensembl chr 8:56,179,637...56,264,263
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO Melphalan results in decreased expression of ARHGAP24 mRNA CTD PMID:22363485 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO Melphalan results in decreased expression of ARHGAP42 mRNA CTD PMID:22363485 NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Melphalan results in increased expression of ARID5A mRNA CTD PMID:22363485 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
JBrowse link
G Atg16l1 autophagy related 16-like 1 increases expression ISO Melphalan results in increased expression of ATG16L1 mRNA CTD PMID:22363485 NCBI chr 9:94,879,876...94,915,231
Ensembl chr 9:94,879,745...94,915,228
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Melphalan results in decreased expression of ATP2B1 mRNA CTD PMID:22363485 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Aurka aurora kinase A increases expression ISO Melphalan results in increased expression of AURKA protein CTD PMID:22025197 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Melphalan results in decreased expression of AURKB protein CTD PMID:22025197 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 increases expression ISO Melphalan results in increased expression of B3GNT2 mRNA CTD PMID:22363485 NCBI chr14:107,592,336...107,617,189
Ensembl chr14:107,592,336...107,617,161
JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Melphalan results in increased expression of B3GNT5 mRNA CTD PMID:22363485 NCBI chr11:84,919,055...84,931,160
Ensembl chr11:84,919,066...84,931,160
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Melphalan results in increased expression of BAK1 protein CTD PMID:22285227 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Melphalan results in increased expression of and results in decreased localization of BAX protein CTD PMID:22285227 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein CTD PMID:4672170 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Melphalan results in decreased expression of BCL2 protein CTD PMID:22285227 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Melphalan results in increased expression of BCL2A1 mRNA CTD PMID:22363485 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bicc1 BicC family RNA binding protein 1 decreases expression ISO Melphalan results in decreased expression of BICC1 mRNA CTD PMID:22363485 NCBI chr20:18,780,605...18,940,429
Ensembl chr20:18,780,605...18,940,408
JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 increases expression ISO Melphalan results in increased expression of BICDL2 mRNA CTD PMID:22363485 NCBI chr10:12,980,696...12,989,133
Ensembl chr10:12,980,674...12,992,780
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects response to substance
decreases expression
multiple interactions
ISO BIRC5 protein affects the susceptibility to Melphalan
Melphalan results in decreased expression of BIRC5 protein
Nocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]; Paclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]
CTD PMID:16373717, PMID:22025197 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnc2 basonuclin 2 decreases expression ISO Melphalan results in decreased expression of BNC2 mRNA CTD PMID:22363485 NCBI chr 5:102,407,508...102,807,389
Ensembl chr 5:102,415,847...102,786,331
JBrowse link
G Btbd8 BTB domain containing 8 decreases expression ISO Melphalan results in decreased expression of BTBD8 mRNA CTD PMID:22363485 NCBI chr14:3,282,422...3,351,740
Ensembl chr14:3,284,089...3,300,200
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Melphalan results in increased expression of BTG2 mRNA CTD PMID:22363485 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression ISO Melphalan results in decreased expression of CABLES1 mRNA CTD PMID:22363485 NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
JBrowse link
G Casp3 caspase 3 increases activity ISO Melphalan results in increased activity of CASP3 protein CTD PMID:16951922 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Melphalan results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:22285227 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases activity ISO Melphalan results in decreased activity of CAT protein CTD PMID:19162187 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO Melphalan results in decreased expression of CC2D2A mRNA CTD PMID:22363485 NCBI chr14:71,895,128...71,979,452
Ensembl chr14:71,895,246...71,973,419
JBrowse link
G Ccdc110 coiled-coil domain containing 110 decreases expression ISO Melphalan results in decreased expression of CCDC110 mRNA CTD PMID:22363485 NCBI chr16:49,509,885...49,522,094
Ensembl chr16:49,509,876...49,522,341
Ensembl chr16:49,509,876...49,522,341
JBrowse link
G Ccdc171 coiled-coil domain containing 171 decreases expression ISO Melphalan results in decreased expression of CCDC171 mRNA CTD PMID:22363485 NCBI chr 5:101,639,355...102,017,300 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Melphalan results in increased expression of CCL20 mRNA CTD PMID:22363485 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccnj cyclin J increases expression ISO Melphalan results in increased expression of CCNJ mRNA CTD PMID:22363485 NCBI chr 1:259,926,537...259,944,275
Ensembl chr 1:260,093,641...260,111,254
Ensembl chr 1:260,093,641...260,111,254
JBrowse link
G Cd34 CD34 molecule multiple interactions ISO [Melphalan co-treated with Prednisolone] results in decreased expression of CD34 protein CTD PMID:10618687 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cd59 CD59 molecule decreases lipidation EXP Melphalan results in decreased lipidation of CD59 protein CTD PMID:27931811 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cda cytidine deaminase decreases response to substance ISO CDA protein results in decreased susceptibility to Melphalan CTD PMID:10830723 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Melphalan results in decreased expression of CDC14B mRNA CTD PMID:22363485 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Melphalan results in decreased expression of CDC42EP3 mRNA CTD PMID:22363485 NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
JBrowse link
G Cfap206 cilia and flagella associated protein 206 decreases expression ISO Melphalan results in decreased expression of CFAP206 mRNA CTD PMID:22363485 NCBI chr 5:50,148,685...50,193,580
Ensembl chr 5:50,148,658...50,193,571
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK1 protein CTD PMID:26208482 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK2 protein CTD PMID:26208482 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex affects phosphorylation ISO Melphalan affects the phosphorylation of CHUK protein CTD PMID:19934314 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator decreases expression ISO Melphalan results in decreased expression of CIITA mRNA CTD PMID:22363485 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 increases expression ISO Melphalan results in increased expression of CITED4 mRNA CTD PMID:22363485 NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622
JBrowse link
G Cnksr3 Cnksr family member 3 decreases expression ISO Melphalan results in decreased expression of CNKSR3 mRNA CTD PMID:22363485 NCBI chr 1:43,789,797...43,884,267
Ensembl chr 1:43,789,791...43,884,267
JBrowse link
G Cpne8 copine 8 decreases expression ISO Melphalan results in decreased expression of CPNE8 mRNA CTD PMID:22363485 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO Melphalan results in decreased expression of CREB5 mRNA CTD PMID:22363485 NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351
JBrowse link
G Cul3 cullin 3 increases expression ISO Melphalan results in increased expression of CUL3 mRNA CTD PMID:22363485 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Melphalan results in decreased expression of CXCL12 mRNA; Melphalan results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Melphalan results in increased expression of CYP27B1 mRNA CTD PMID:22363485 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyria CYFIP related Rac1 interactor A decreases expression ISO Melphalan results in decreased expression of CYRIA mRNA CTD PMID:22363485 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO Melphalan results in increased expression of DBF4 mRNA CTD PMID:22363485 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Dcn decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dennd4c DENN domain containing 4C decreases expression ISO Melphalan results in decreased expression of DENND4C mRNA CTD PMID:22363485 NCBI chr 5:105,100,081...105,195,634
Ensembl chr 5:105,114,433...105,193,988
JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 decreases expression ISO Melphalan results in decreased expression of DLG3 mRNA CTD PMID:22363485 NCBI chr  X:70,596,246...70,648,529
Ensembl chr  X:70,596,576...70,648,532
JBrowse link
G Dst dystonin decreases expression ISO Melphalan results in decreased expression of DST mRNA CTD PMID:22363485 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Melphalan results in increased expression of DUSP2 mRNA CTD PMID:22363485 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Eaf1 ELL associated factor 1 increases expression ISO Melphalan results in increased expression of EAF1 mRNA CTD PMID:22363485 NCBI chr16:7,588,217...7,602,966
Ensembl chr16:7,588,217...7,602,966
JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Melphalan results in decreased expression of EBF1 mRNA CTD PMID:22363485 NCBI chr10:23,654,849...24,051,627
Ensembl chr10:23,661,013...24,050,209
JBrowse link
G Edn1 endothelin 1 increases expression ISO Melphalan results in increased expression of EDN1 protein CTD PMID:18548196 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 decreases expression ISO Melphalan results in decreased expression of EEPD1 mRNA CTD PMID:22363485 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
JBrowse link
G Efna2 ephrin A2 increases expression ISO Melphalan results in increased expression of EFNA2 mRNA CTD PMID:22363485 NCBI chr 7:12,382,636...12,393,266
Ensembl chr 7:12,382,636...12,393,266
JBrowse link
G Efna5 ephrin A5 decreases expression ISO Melphalan results in decreased expression of EFNA5 mRNA CTD PMID:22363485 NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486
JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Melphalan results in decreased expression of EMX2 mRNA CTD PMID:22363485 NCBI chr 1:280,633,938...280,640,946
Ensembl chr 1:280,633,938...280,640,946
JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 decreases expression ISO Melphalan results in decreased expression of ENOX1 mRNA CTD PMID:22363485 NCBI chr15:59,331,134...59,884,512
Ensembl chr15:59,678,165...59,884,511
JBrowse link
G Epha5 EPH receptor A5 decreases expression ISO Melphalan results in decreased expression of EPHA5 mRNA CTD PMID:22363485 NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227
JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO Melphalan results in decreased expression of EXOC6 mRNA CTD PMID:22363485 NCBI chr 1:256,211,879...256,369,318
Ensembl chr 1:256,226,179...256,368,813
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Melphalan results in increased expression of FABP5 mRNA CTD PMID:22363485 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fam110b family with sequence similarity 110, member B decreases expression ISO Melphalan results in decreased expression of FAM110B mRNA CTD PMID:22363485 NCBI chr 5:18,762,488...18,903,818
Ensembl chr 5:18,901,039...18,902,672
JBrowse link
G Fam90a1 family with sequence similarity 90, member A1 decreases expression ISO Melphalan results in decreased expression of FAM90A1 mRNA CTD PMID:22363485 NCBI chr16:75,001,033...75,016,173 JBrowse link
G Fancc FA complementation group C increases response to substance ISO FANCC protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Fancg FA complementation group G increases response to substance ISO FANCG protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO Melphalan results in decreased expression of FAT4 mRNA CTD PMID:22363485 NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 decreases expression ISO Melphalan results in decreased expression of FGD4 mRNA CTD PMID:22363485 NCBI chr11:88,699,222...88,796,677
Ensembl chr11:88,699,222...88,796,677
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 decreases expression ISO Melphalan results in decreased expression of FGD6 mRNA CTD PMID:22363485 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Melphalan results in decreased expression of FGF5 mRNA CTD PMID:22363485 NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
JBrowse link
G Fign fidgetin, microtubule severing factor decreases expression ISO Melphalan results in decreased expression of FIGN mRNA CTD PMID:22363485 NCBI chr 3:49,992,250...50,120,601
Ensembl chr 3:49,992,397...50,120,392
JBrowse link
G Fmn2 formin 2 decreases expression ISO Melphalan results in decreased expression of FMN2 mRNA CTD PMID:22363485 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Melphalan results in increased expression of FOSB mRNA CTD PMID:22363485 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Foxp2 forkhead box P2 decreases expression ISO Melphalan results in decreased expression of FOXP2 mRNA CTD PMID:22363485 NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023
JBrowse link
G Frmd4a FERM domain containing 4A decreases expression ISO Melphalan results in decreased expression of FRMD4A mRNA CTD PMID:22363485 NCBI chr17:77,642,302...77,918,210 JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO Melphalan results in decreased expression of FRMD4B mRNA CTD PMID:22363485 NCBI chr 4:129,658,137...129,984,735
Ensembl chr 4:129,658,840...129,846,642
JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO Melphalan results in decreased expression of FRY mRNA CTD PMID:22363485 NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
JBrowse link
G Fut10 fucosyltransferase 10 decreases expression ISO Melphalan results in decreased expression of FUT10 mRNA CTD PMID:22363485 NCBI chr16:64,623,246...64,716,248
Ensembl chr16:64,631,264...64,716,224
JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression ISO Melphalan results in decreased expression of GAB1 mRNA CTD PMID:22363485 NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008
JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 decreases expression ISO Melphalan results in decreased expression of GAREM1 mRNA CTD PMID:22363485 NCBI chr18:14,982,604...15,007,245 JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO Melphalan results in decreased expression of GAS1 mRNA CTD PMID:22363485 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 decreases expression ISO Melphalan results in decreased expression of GCNT1 mRNA CTD PMID:22363485 NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035
JBrowse link
G Gli3 GLI family zinc finger 3 decreases expression ISO Melphalan results in decreased expression of GLI3 mRNA CTD PMID:22363485 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression ISO Melphalan results in increased expression of GRIN2C mRNA CTD PMID:22363485 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 decreases expression ISO Melphalan results in decreased expression of GRK5 mRNA CTD PMID:22363485 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases response to substance EXP GSTA5 protein results in decreased susceptibility to Melphalan CTD PMID:12076520 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases response to substance ISO GSTM1 protein results in decreased susceptibility to Melphalan CTD PMID:20067466 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]; Melphalan inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:12791655, PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression ISO Melphalan results in decreased expression of HECW2 mRNA CTD PMID:22363485 NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO Melphalan results in decreased expression of HGF mRNA CTD PMID:22363485 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO Melphalan results in decreased expression of HMGA2 mRNA CTD PMID:22363485 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hoxd1 homeo box D1 increases expression ISO Melphalan results in increased expression of HOXD1 mRNA CTD PMID:22363485 NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Melphalan results in increased expression of ICAM1 protein CTD PMID:16025434 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ier3 immediate early response 3 increases expression ISO Melphalan results in increased expression of IER3 mRNA CTD PMID:22363485 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO Melphalan results in decreased expression of IKBKE mRNA CTD PMID:22363485 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Melphalan results in decreased expression of IKZF2 mRNA CTD PMID:22363485 NCBI chr 9:76,621,230...76,771,017
Ensembl chr 9:76,621,230...76,768,806
JBrowse link
G Il12a interleukin 12A increases expression ISO Melphalan results in increased expression of IL12A mRNA CTD PMID:22363485 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il16 interleukin 16 decreases expression ISO Melphalan results in decreased expression of IL16 mRNA CTD PMID:22363485 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Melphalan results in increased expression of and results in increased secretion of IL1B protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]
Melphalan results in increased expression of IL1B mRNA
CTD PMID:21129433, PMID:22363485 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions
ISO Melphalan results in increased expression of IL23A protein
TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]
CTD PMID:21129433 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Melphalan results in increased expression of and results in increased secretion of IL6 protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein] CTD PMID:21129433 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 decreases expression ISO Melphalan results in decreased expression of IL7 mRNA CTD PMID:22363485 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO Melphalan results in decreased expression of IRF2 mRNA CTD PMID:22363485 NCBI chr16:48,582,354...48,732,129
Ensembl chr16:48,582,026...48,732,932
JBrowse link
G Jade2 jade family PHD finger 2 decreases expression ISO Melphalan results in decreased expression of JADE2 mRNA CTD PMID:22363485 NCBI chr10:37,269,132...37,315,638
Ensembl chr10:37,270,183...37,311,625
JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO Melphalan results in decreased expression of JAK2 mRNA CTD PMID:22363485 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 decreases expression ISO Melphalan results in decreased expression of JAKMIP3 mRNA CTD PMID:22363485 NCBI chr 1:211,292,604...211,421,023
Ensembl chr 1:211,351,350...211,421,022
JBrowse link
G Kalrn kalirin, RhoGEF kinase decreases expression ISO Melphalan results in decreased expression of KALRN mRNA CTD PMID:22363485 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Kbtbd3 kelch repeat and BTB domain containing 3 decreases expression ISO Melphalan results in decreased expression of KBTBD3 mRNA CTD PMID:22363485 NCBI chr 8:1,450,345...1,477,250
Ensembl chr 8:1,459,526...1,476,837
JBrowse link
G Kitlg KIT ligand decreases expression ISO Melphalan results in decreased expression of KITLG mRNA CTD PMID:22363485 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf12 Kruppel-like factor 12 decreases expression ISO Melphalan results in decreased expression of KLF12 mRNA CTD PMID:22363485 NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Melphalan results in increased expression of KLHL42 mRNA CTD PMID:22363485 NCBI chr 4:181,481,147...181,502,916
Ensembl chr 4:181,481,147...181,502,916
JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO Melphalan results in decreased expression of LRIG3 mRNA CTD PMID:22363485 NCBI chr 7:69,213,098...69,263,251
Ensembl chr 7:69,213,147...69,263,142
JBrowse link
G Lurap1 leucine rich adaptor protein 1 decreases expression ISO Melphalan results in decreased expression of LURAP1 mRNA CTD PMID:22363485 NCBI chr 5:134,991,997...135,001,720
Ensembl chr 5:134,991,997...135,001,720
JBrowse link
G Lyst lysosomal trafficking regulator decreases expression ISO Melphalan results in decreased expression of LYST mRNA CTD PMID:22363485 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:16025434 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16025434 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Melphalan results in decreased expression of MBOAT1 mRNA CTD PMID:22363485 NCBI chr17:36,061,775...36,177,457
Ensembl chr17:36,061,775...36,177,457
JBrowse link
G Meox2 mesenchyme homeobox 2 decreases expression ISO Melphalan results in decreased expression of MEOX2 mRNA CTD PMID:22363485 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mex3a mex-3 RNA binding family member A increases expression ISO Melphalan results in increased expression of MEX3A mRNA CTD PMID:22363485 NCBI chr 2:187,893,678...187,902,546
Ensembl chr 2:187,893,368...187,898,310
JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression ISO Melphalan results in increased expression of MEX3B mRNA CTD PMID:22363485 NCBI chr 1:144,831,523...144,835,758
Ensembl chr 1:144,831,523...144,835,747
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A increases expression ISO Melphalan results in increased expression of MFSD2A mRNA CTD PMID:22363485 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases response to substance ISO MGST2 protein results in decreased susceptibility to Melphalan CTD PMID:15779864 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Melphalan results in decreased expression of MITF mRNA CTD PMID:22363485 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mllt3 MLLT3, super elongation complex subunit decreases expression ISO Melphalan results in decreased expression of MLLT3 mRNA CTD PMID:22363485 NCBI chr 5:106,103,498...106,202,559
Ensembl chr 5:106,103,407...106,207,126
JBrowse link
G Mms22l MMS22-like, DNA repair protein decreases expression ISO Melphalan results in decreased expression of MMS22L mRNA CTD PMID:22363485 NCBI chr 5:38,844,502...38,960,989
Ensembl chr 5:38,844,488...38,961,035
JBrowse link
G Mrtfb myocardin related transcription factor B decreases expression ISO Melphalan results in decreased expression of MRTFB mRNA CTD PMID:22363485 NCBI chr10:1,151,163...1,273,269 JBrowse link
G Mta3 metastasis associated 1 family, member 3 decreases expression ISO Melphalan results in decreased expression of MTA3 mRNA CTD PMID:22363485 NCBI chr 6:6,904,449...7,036,929
Ensembl chr 6:6,908,684...7,031,828
JBrowse link
G Mtcl1 microtubule crosslinking factor 1 decreases expression ISO Melphalan results in decreased expression of MTCL1 mRNA CTD PMID:22363485 NCBI chr 9:114,493,901...114,632,632
Ensembl chr 9:114,491,419...114,619,711
JBrowse link
G Myo1b myosin Ib decreases expression ISO Melphalan results in decreased expression of MYO1B mRNA CTD PMID:22363485 NCBI chr 9:54,706,005...54,766,054
Ensembl chr 9:54,558,202...54,766,054
JBrowse link
G Nebl nebulette increases expression ISO Melphalan results in increased expression of NEBL mRNA CTD PMID:22363485 NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
JBrowse link
G Nfia nuclear factor I/A decreases expression ISO Melphalan results in decreased expression of NFIA mRNA CTD PMID:22363485 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416
JBrowse link
G Nhs NHS actin remodeling regulator decreases expression ISO Melphalan results in decreased expression of NHS mRNA CTD PMID:22363485 NCBI chr  X:34,312,102...34,675,912
Ensembl chr  X:34,623,405...34,673,742
JBrowse link
G Nkrf NFKB repressing factor increases expression ISO Melphalan results in increased expression of NKRF mRNA CTD PMID:22363485 NCBI chr  X:123,502,074...123,516,301
Ensembl chr  X:123,502,096...123,515,720
JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO Melphalan results in increased expression of NOP56 mRNA CTD PMID:22363485 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558
JBrowse link
G Nppb natriuretic peptide B increases expression ISO Melphalan results in increased expression of NPPB protein CTD PMID:18548196 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Melphalan results in increased expression of NR4A3 mRNA CTD PMID:22363485 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nrg2 neuregulin 2 decreases expression ISO Melphalan results in decreased expression of NRG2 mRNA CTD PMID:22363485 NCBI chr18:28,835,391...29,015,552
Ensembl chr18:28,835,417...29,015,552
JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO Melphalan results in decreased expression of NRP1 mRNA CTD PMID:22363485 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Melphalan results in decreased expression of NUAK1 mRNA CTD PMID:22363485 NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664
JBrowse link
G Osbpl10 oxysterol binding protein-like 10 decreases expression ISO Melphalan results in decreased expression of OSBPL10 mRNA CTD PMID:22363485 NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562
JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Melphalan results in decreased expression of PAG1 mRNA CTD PMID:22363485 NCBI chr 2:94,266,104...94,277,680
Ensembl chr 2:94,266,213...94,277,676
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Melphalan results in decreased expression of PDLIM5 mRNA CTD PMID:22363485 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462
JBrowse link
G Phf21a PHD finger protein 21A decreases expression ISO Melphalan results in decreased expression of PHF21A mRNA CTD PMID:22363485 NCBI chr 3:81,099,765...81,271,841
Ensembl chr 3:81,134,505...81,271,849
JBrowse link
G Phf3 PHD finger protein 3 decreases expression ISO Melphalan results in decreased expression of PHF3 mRNA CTD PMID:22363485 NCBI chr 9:37,073,514...37,144,027
Ensembl chr 9:37,073,514...37,144,015
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Melphalan results in increased expression of PHLDA1 mRNA CTD PMID:22363485 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases expression ISO Melphalan results in decreased expression of PHLDB2 mRNA CTD PMID:22363485 NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis
multiple interactions
EXP Melphalan results in increased mutagenesis of PIGA
Melphalan results in increased mutagenesis of and results in decreased activity of PIGA protein
CTD PMID:22923490, PMID:27931811 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO Melphalan results in decreased expression of PIK3R1 mRNA CTD PMID:22363485 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO Melphalan results in decreased expression of PIK3R3 mRNA CTD PMID:22363485 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression ISO Melphalan results in decreased expression of PLCL2 mRNA CTD PMID:22363485 NCBI chr 9:1,782,536...1,984,654
Ensembl chr 9:1,782,536...1,984,654
JBrowse link
G Plekha2 pleckstrin homology domain containing A2 decreases expression ISO Melphalan results in decreased expression of PLEKHA2 mRNA CTD PMID:22363485 NCBI chr16:71,725,649...71,784,432
Ensembl chr16:71,738,718...71,787,787
JBrowse link
G Plekha5 pleckstrin homology domain containing A5 decreases expression ISO Melphalan results in decreased expression of PLEKHA5 mRNA CTD PMID:22363485 NCBI chr 4:174,605,462...174,774,692
Ensembl chr 4:174,605,476...174,774,693
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Melphalan results in increased expression of PLK3 mRNA CTD PMID:22363485 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Ppif peptidylprolyl isomerase F increases expression ISO Melphalan results in increased expression of PPIF mRNA CTD PMID:22363485 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H decreases expression ISO Melphalan results in decreased expression of PPM1H mRNA CTD PMID:22363485 NCBI chr 7:66,845,692...67,116,979
Ensembl chr 7:66,843,865...67,116,980
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO Melphalan results in decreased expression of PPP2R2B mRNA CTD PMID:22363485 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha decreases expression ISO Melphalan results in decreased expression of PPP2R5A mRNA CTD PMID:22363485 NCBI chr13:110,033,550...110,077,946
Ensembl chr13:110,033,550...110,077,946
JBrowse link
G Prune2 prune homolog 2 with BCH domain decreases expression ISO Melphalan results in decreased expression of PRUNE2 mRNA CTD PMID:22363485 NCBI chr 1:236,676,963...236,947,527
Ensembl chr 1:236,680,098...236,729,412
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 decreases expression ISO Melphalan results in decreased expression of PSD3 mRNA CTD PMID:22363485 NCBI chr16:23,212,165...23,789,414
Ensembl chr16:23,447,366...23,781,604
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Melphalan results in increased expression of PTGS2 mRNA CTD PMID:22363485 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression ISO Melphalan results in decreased expression of PTPRG mRNA CTD PMID:22363485 NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607
JBrowse link
G Pxk PX domain containing serine/threonine kinase decreases expression ISO Melphalan results in decreased expression of PXK mRNA CTD PMID:22363485 NCBI chr15:18,548,209...18,616,617
Ensembl chr15:18,548,212...18,616,589
JBrowse link
G Rad54b RAD54 homolog B decreases expression ISO Melphalan results in decreased expression of RAD54B mRNA CTD PMID:22363485 NCBI chr 5:25,140,531...25,214,469
Ensembl chr 5:25,146,949...25,214,376
JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked decreases expression ISO Melphalan results in decreased expression of RADX mRNA CTD PMID:22363485 NCBI chr  X:110,670,037...110,782,420
Ensembl chr  X:110,670,119...110,782,284
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO Melphalan results in decreased expression of RARB mRNA CTD PMID:22363485 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO Melphalan results in increased expression of RASD1 mRNA CTD PMID:22363485 NCBI chr10:46,330,361...46,339,326
Ensembl chr10:46,330,368...46,332,172
JBrowse link
G Rasl10a RAS-like, family 10, member A increases expression ISO Melphalan results in increased expression of RASL10A mRNA CTD PMID:22363485 NCBI chr14:85,311,833...85,313,211
Ensembl chr14:85,311,089...85,314,270
JBrowse link
G Rasl11b RAS-like family 11 member B increases expression ISO Melphalan results in increased expression of RASL11B mRNA CTD PMID:22363485 NCBI chr14:36,550,353...36,554,574
Ensembl chr14:36,550,340...36,554,580
JBrowse link
G Rbm24 RNA binding motif protein 24 increases expression ISO Melphalan results in increased expression of RBM24 mRNA CTD PMID:22363485 NCBI chr17:18,671,037...18,682,876
Ensembl chr17:18,671,044...18,682,876
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit decreases expression ISO Melphalan results in decreased expression of REV3L mRNA CTD PMID:22363485 NCBI chr20:44,803,664...44,961,362
Ensembl chr20:44,803,666...44,961,382
JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 decreases expression ISO Melphalan results in decreased expression of RGL1 mRNA CTD PMID:22363485 NCBI chr13:69,909,122...70,174,590
Ensembl chr13:69,909,096...70,174,565
JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b decreases expression ISO Melphalan results in decreased expression of RGMB mRNA CTD PMID:22363485 NCBI chr 1:57,794,046...57,819,941
Ensembl chr 1:57,796,709...57,815,038
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Melphalan results in increased expression of RGS16 mRNA CTD PMID:22363485 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Melphalan results in increased expression of RGS2 mRNA CTD PMID:22363485 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 decreases expression ISO Melphalan results in decreased expression of RIPOR2 mRNA CTD PMID:22363485 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053
JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Melphalan results in decreased expression of RNF128 mRNA CTD PMID:22363485 NCBI chr  X:110,789,061...110,877,964
Ensembl chr  X:110,789,269...110,877,978
JBrowse link
G Rnf144b ring finger protein 144B decreases expression ISO Melphalan results in decreased expression of RNF144B mRNA CTD PMID:22363485 NCBI chr17:17,817,122...17,947,777
Ensembl chr17:17,817,100...17,947,777
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO Melphalan results in decreased expression of ROR1 mRNA CTD PMID:22363485 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
JBrowse link
G Rpl27a ribosomal protein L27a increases expression ISO Melphalan results in increased expression of RPL27A mRNA CTD PMID:22363485 NCBI chr 1:174,132,798...174,135,816
Ensembl chr 1:174,132,798...174,135,816
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Melphalan results in increased expression of RRAD mRNA CTD PMID:22363485 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Rspo2 R-spondin 2 decreases expression ISO Melphalan results in decreased expression of RSPO2 mRNA CTD PMID:22363485 NCBI chr 7:81,919,911...82,059,659
Ensembl chr 7:81,924,050...82,059,789
JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 decreases expression ISO Melphalan results in decreased expression of RUNX1T1 mRNA CTD PMID:22363485 NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 decreases expression ISO Melphalan results in decreased expression of SCN8A mRNA CTD PMID:22363485 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
G Sema6d semaphorin 6D decreases expression ISO Melphalan results in decreased expression of SEMA6D mRNA CTD PMID:22363485 NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Melphalan results in increased expression of SERPINB2 mRNA CTD PMID:22363485 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Melphalan results in increased expression of SGK1 mRNA CTD PMID:22363485 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO Melphalan results in decreased expression of SGMS1 mRNA CTD PMID:22363485 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 decreases expression ISO Melphalan results in decreased expression of SHANK2 mRNA CTD PMID:22363485 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shroom3 shroom family member 3 decreases expression ISO Melphalan results in decreased expression of SHROOM3 mRNA CTD PMID:22363485 NCBI chr14:16,622,767...16,903,265
Ensembl chr14:16,622,760...16,903,242
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Melphalan results in increased expression of SIK1 mRNA CTD PMID:22363485 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO Melphalan results in decreased expression of SLC14A1 mRNA CTD PMID:22363485 NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139
JBrowse link
G Slc19a2 solute carrier family 19 member 2 increases expression ISO Melphalan results in increased expression of SLC19A2 mRNA CTD PMID:22363485 NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586
JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Melphalan results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO Melphalan results in decreased expression of SMAD3 mRNA CTD PMID:22363485 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sntb1 syntrophin, beta 1 decreases expression ISO Melphalan results in decreased expression of SNTB1 mRNA CTD PMID:22363485 NCBI chr 7:95,395,417...95,670,093
Ensembl chr 7:95,397,113...95,669,809
JBrowse link
G Snx29 sorting nexin 29 decreases expression ISO Melphalan results in decreased expression of SNX29 mRNA CTD PMID:22363485 NCBI chr10:3,838,444...4,249,741
Ensembl chr10:3,840,622...4,249,739
JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression ISO Melphalan results in decreased expression of SOCS5 mRNA CTD PMID:22363485 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
JBrowse link
G Spata17 spermatogenesis associated 17 decreases expression ISO Melphalan results in decreased expression of SPATA17 mRNA CTD PMID:22363485 NCBI chr13:105,489,121...105,684,293
Ensembl chr13:105,489,074...105,684,374
JBrowse link
G Spata7 spermatogenesis associated 7 decreases expression ISO Melphalan results in decreased expression of SPATA7 mRNA CTD PMID:22363485 NCBI chr 6:122,603,248...122,648,718
Ensembl chr 6:122,603,269...122,648,699
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 decreases expression ISO Melphalan results in decreased expression of SPRED1 mRNA CTD PMID:22363485 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556
JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 increases expression ISO Melphalan results in increased expression of SPTY2D1 mRNA CTD PMID:22363485 NCBI chr 1:103,115,280...103,129,438
Ensembl chr 1:103,115,216...103,128,743
JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 decreases expression ISO Melphalan results in decreased expression of SRGAP2 mRNA CTD PMID:22363485 NCBI chr13:48,065,280...48,286,888
Ensembl chr13:48,068,158...48,286,720
JBrowse link
G Stac SH3 and cysteine rich domain decreases expression ISO Melphalan results in decreased expression of STAC mRNA CTD PMID:22363485 NCBI chr 8:119,820,664...119,941,867
Ensembl chr 8:119,821,901...119,889,661
JBrowse link
G Stambpl1 STAM binding protein-like 1 decreases expression ISO Melphalan results in decreased expression of STAMBPL1 mRNA CTD PMID:22363485 NCBI chr 1:252,490,125...252,536,113
Ensembl chr 1:252,497,452...252,536,104
JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO Melphalan results in decreased expression of TACC2 mRNA CTD PMID:22363485 NCBI chr 1:201,140,264...201,329,612
Ensembl chr 1:201,055,644...201,329,622
JBrowse link
G Tbc1d12 TBC1 domain family, member 12 decreases expression ISO Melphalan results in decreased expression of TBC1D12 mRNA CTD PMID:22363485 NCBI chr 1:257,517,128...257,599,659
Ensembl chr 1:257,517,242...257,883,971
JBrowse link
G Tbl1xr1 TBL1X receptor 1 decreases expression ISO Melphalan results in decreased expression of TBL1XR1 mRNA CTD PMID:22363485 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 decreases expression ISO Melphalan results in decreased expression of TET1 mRNA CTD PMID:22363485 NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427
JBrowse link
G Tex30 testis expressed 30 increases expression ISO Melphalan results in increased expression of TEX30 mRNA CTD PMID:22363485 NCBI chr 9:50,858,737...50,868,238
Ensembl chr 9:50,858,737...50,868,238
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Melphalan results in increased expression of TFPI2 mRNA CTD PMID:22363485 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa] CTD PMID:9509296 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 decreases expression ISO Melphalan results in decreased expression of THSD4 mRNA CTD PMID:22363485 NCBI chr 8:64,811,940...65,413,498
Ensembl chr 8:64,817,191...65,003,296
JBrowse link
G Tigd2 tigger transposable element derived 2 decreases expression ISO Melphalan results in decreased expression of TIGD2 mRNA CTD PMID:22363485 NCBI chr 4:89,535,418...89,538,535
Ensembl chr 4:89,536,647...89,538,227
JBrowse link
G Tlnrd1 talin rod domain containing 1 increases expression ISO Melphalan results in increased expression of TLNRD1 mRNA CTD PMID:22363485 NCBI chr 1:146,027,821...146,029,840
Ensembl chr 1:146,027,822...146,029,840
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Melphalan results in decreased expression of TLR4 mRNA CTD PMID:22363485 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmem131l transmembrane 131 like decreases expression ISO Melphalan results in decreased expression of TMEM131L mRNA CTD PMID:22363485 NCBI chr 2:182,897,332...183,031,273
Ensembl chr 2:182,897,830...183,031,214
JBrowse link
G Tmem200a transmembrane protein 200A decreases expression ISO Melphalan results in decreased expression of TMEM200A mRNA CTD PMID:22363485 NCBI chr 1:20,330,670...20,413,921
Ensembl chr 1:20,331,976...20,412,381
JBrowse link
G Tmem26 transmembrane protein 26 decreases expression ISO Melphalan results in decreased expression of TMEM26 mRNA CTD PMID:22363485 NCBI chr20:21,640,655...21,689,655
Ensembl chr20:21,642,484...21,689,553
JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Melphalan results in increased expression of TMEM88 mRNA CTD PMID:22363485 NCBI chr10:55,998,530...56,000,225
Ensembl chr10:55,998,530...56,000,225
JBrowse link
G Tnf tumor necrosis factor increases expression ISO Melphalan results in increased expression of TNF mRNA CTD PMID:16025434 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 decreases expression ISO Melphalan results in decreased expression of TNFRSF19 mRNA CTD PMID:22363485 NCBI chr15:41,249,820...41,316,203
Ensembl chr15:41,246,308...41,338,284
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Melphalan results in increased expression of TNNI3 protein CTD PMID:18548196 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B decreases expression ISO Melphalan results in decreased expression of TNRC6B mRNA CTD PMID:22363485 NCBI chr 7:121,930,610...122,147,934
Ensembl chr 7:121,930,615...122,147,934
JBrowse link
G Tox thymocyte selection-associated high mobility group box decreases expression ISO Melphalan results in decreased expression of TOX mRNA CTD PMID:22363485 NCBI chr 5:19,892,698...20,189,721
Ensembl chr 5:19,892,698...20,189,721
JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Melphalan results in decreased expression of TP63 mRNA CTD PMID:22363485 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Trerf1 transcriptional regulating factor 1 decreases expression ISO Melphalan results in decreased expression of TRERF1 mRNA CTD PMID:22363485 NCBI chr 9:15,653,230...15,881,695
Ensembl chr 9:15,655,735...15,700,312
JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Melphalan results in increased expression of TRIB1 mRNA CTD PMID:22363485 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit increases expression ISO Melphalan results in increased expression of TRMT10C mRNA CTD PMID:22363485 NCBI chr11:47,047,342...47,052,420
Ensembl chr11:47,047,342...47,052,418
JBrowse link
G Ttc30b tetratricopeptide repeat domain 30B decreases expression ISO Melphalan results in decreased expression of TTC30B mRNA CTD PMID:22363485 NCBI chr 3:62,758,754...62,761,325
Ensembl chr 3:62,758,758...62,761,325
JBrowse link
G Tubg1 tubulin, gamma 1 increases expression ISO Melphalan results in increased expression of TUBG1 protein CTD PMID:22025197 NCBI chr10:89,030,865...89,037,455
Ensembl chr10:89,030,865...89,037,455
JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Melphalan results in increased expression of TUFT1 mRNA CTD PMID:22363485 NCBI chr 2:195,861,772...195,907,471
Ensembl chr 2:195,861,649...195,908,037
JBrowse link
G Twnk twinkle mtDNA helicase increases expression ISO Melphalan results in increased expression of TWNK mRNA CTD PMID:22363485 NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP Melphalan results in decreased activity of TXNRD1 protein CTD PMID:16085187 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ubap1l ubiquitin associated protein 1-like increases expression ISO Melphalan results in increased expression of UBAP1L mRNA CTD PMID:22363485 NCBI chr 8:70,876,516...70,895,723
Ensembl chr 8:70,884,491...70,896,501
JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Melphalan results in increased expression of USP36 mRNA CTD PMID:22363485 NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355
JBrowse link
G Usp53 ubiquitin specific peptidase 53 decreases expression ISO Melphalan results in decreased expression of USP53 mRNA CTD PMID:22363485 NCBI chr 2:227,098,795...227,160,385
Ensembl chr 2:227,098,795...227,160,379
JBrowse link
G Utp25 UTP25, small subunit processor component increases expression ISO Melphalan results in increased expression of UTP25 mRNA CTD PMID:22363485 NCBI chr13:111,828,052...111,849,654
Ensembl chr13:111,828,043...111,849,653
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [arsenic trioxide results in increased expression of VDAC1 protein] which results in increased susceptibility to Melphalan CTD PMID:22285227 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Yod1 YOD1 deubiquitinase increases expression ISO Melphalan results in increased expression of YOD1 mRNA CTD PMID:22363485 NCBI chr13:47,441,296...47,443,013
Ensembl chr13:47,440,803...47,443,188
JBrowse link
G Ypel2 yippee-like 2 decreases expression ISO Melphalan results in decreased expression of YPEL2 mRNA CTD PMID:22363485 NCBI chr10:74,241,032...74,298,691
Ensembl chr10:74,243,812...74,298,599
JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing increases expression ISO Melphalan results in increased expression of YRDC mRNA CTD PMID:22363485 NCBI chr 5:142,845,265...142,850,110
Ensembl chr 5:142,845,114...142,850,111
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression ISO Melphalan results in decreased expression of ZBTB20 mRNA CTD PMID:22363485 NCBI chr11:62,014,925...62,561,113
Ensembl chr11:62,014,925...62,451,184
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Melphalan results in increased expression of ZC3H12A mRNA CTD PMID:22363485 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO Melphalan results in decreased expression of ZFHX4 mRNA CTD PMID:22363485 NCBI chr 2:98,423,565...98,610,368
Ensembl chr 2:98,423,569...98,610,368
JBrowse link
G Zfp277 zinc finger protein 277 decreases expression ISO Melphalan results in decreased expression of ZNF277 mRNA CTD PMID:22363485 NCBI chr 6:60,246,209...60,374,388
Ensembl chr 6:60,246,214...60,374,389
JBrowse link
G Zfp438 zinc finger protein 438 decreases expression ISO Melphalan results in decreased expression of ZNF438 mRNA CTD PMID:22363485 NCBI chr17:55,006,893...55,131,567
Ensembl chr17:55,008,265...55,129,555
JBrowse link
G Zfp521 zinc finger protein 521 decreases expression ISO Melphalan results in decreased expression of ZNF521 mRNA CTD PMID:22363485 NCBI chr18:5,022,042...5,315,242
Ensembl chr18:5,032,029...5,314,585
JBrowse link
G Zfp618 zinc finger protein 618 decreases expression ISO Melphalan results in decreased expression of ZNF618 mRNA CTD PMID:22363485 NCBI chr 5:78,806,585...78,972,433
Ensembl chr 5:78,806,607...78,966,813
JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression ISO Melphalan results in decreased expression of ZSWIM5 mRNA CTD PMID:22363485 NCBI chr 5:135,735,825...135,854,525
Ensembl chr 5:135,735,825...135,852,575
JBrowse link
N(omega)-methyl-L-arginine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
rhodotorulic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
S-(1,2-dichlorovinyl)-L-cysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of APAF1 protein CTD PMID:15967204 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of BAX protein CTD PMID:15967204 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of BCL2 protein CTD PMID:15967204 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP3 protein] CTD PMID:29129777 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
ISO S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein
alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]
CTD PMID:29129777 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases activity ISO S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP8 protein CTD PMID:29129777 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases cleavage
increases activity
ISO S-(1,2-dichlorovinyl)cysteine results in increased cleavage of CASP9 protein
S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP9 protein
CTD PMID:15967204, PMID:29129777 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of CCND1 protein CTD PMID:16495211 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of CDK4 protein CTD PMID:16495211 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of CDK6 protein CTD PMID:16495211 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO S-(1,2-dichlorovinyl)cysteine results in decreased expression of CDKN2A protein CTD PMID:16495211 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Dld dihydrolipoamide dehydrogenase multiple interactions
decreases activity
EXP Aminooxyacetic Acid inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in decreased activity of DLD protein] CTD PMID:2360207 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP S-(1,2-dichlorovinyl)cysteine results in decreased activity of GSR protein CTD PMID:2360207 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of JUN protein CTD PMID:15967204 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO S-(1,2-dichlorovinyl)cysteine results in increased cleavage of PARP1 protein CTD PMID:15967204 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha increases phosphorylation
decreases expression
ISO S-(1,2-dichlorovinyl)cysteine results in increased phosphorylation of PPP1CA protein
S-(1,2-dichlorovinyl)cysteine results in decreased expression of PPP1CA protein
CTD PMID:16495211 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases phosphorylation ISO S-(1,2-dichlorovinyl)cysteine results in increased phosphorylation of RB1 protein CTD PMID:16495211 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of RELA protein CTD PMID:15967204 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Slc25a10 solute carrier family 25 member 10 multiple interactions EXP [SLC25A10 protein co-treated with Glutathione] results in decreased susceptibility to S-(1,2-dichlorovinyl)cysteine CTD PMID:12388626 NCBI chr10:109,665,682...109,674,782
Ensembl chr10:109,665,682...109,673,143
JBrowse link
G Tp53 tumor protein p53 increases expression ISO S-(1,2-dichlorovinyl)cysteine results in increased expression of TP53 protein CTD PMID:15967204 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vim vimentin increases expression EXP S-(1,2-dichlorovinyl)cysteine results in increased expression of VIM mRNA CTD PMID:10996665 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
S-allylcysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases phosphorylation
ISO dorsomorphin inhibits the reaction [S-allylcysteine results in increased phosphorylation of ACACA protein]; S-allylcysteine promotes the reaction [Fatty Acids, Nonesterified results in increased phosphorylation of ACACA protein]; sirtinol inhibits the reaction [S-allylcysteine results in increased phosphorylation of ACACA protein]; STO 609 inhibits the reaction [S-allylcysteine results in increased phosphorylation of ACACA protein] CTD PMID:23465592 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
[S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]
S-allylcysteine results in decreased expression of BCL2 protein
CTD PMID:16030430, PMID:17155983 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions EXP S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein] CTD PMID:16030430 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases phosphorylation ISO S-allylcysteine results in increased phosphorylation of CAMK2A protein CTD PMID:23465592 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO
EXP
S-allylcysteine results in increased cleavage of CASP3 protein
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP3 protein]; S-allylcysteine inhibits the reaction [lead acetate results in increased activity of CASP3 protein]
[S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]
CTD PMID:16030430, PMID:17155983, PMID:22033380 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
EXP
ISO
[S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
S-allylcysteine results in increased activity of CASP8 protein
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP8 protein]; S-allylcysteine inhibits the reaction [Diethylnitrosamine results in decreased activity of CASP8 protein]; S-allylcysteine inhibits the reaction [lead acetate results in increased activity of CASP8 protein]
CTD PMID:16030430, PMID:22033380, PMID:31067004 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions EXP
ISO
S-allylcysteine inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; S-allylcysteine inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in decreased activity of CAT protein]; S-allylcysteine inhibits the reaction [lead acetate results in decreased activity of CAT protein]
CTD PMID:18548744, PMID:19391111, PMID:20951120, PMID:22033380 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdh1 cadherin 1 increases expression ISO S-allylcysteine results in increased expression of CDH1 protein CTD PMID:17155983 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Ctsd cathepsin D multiple interactions EXP S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA] CTD PMID:17182065 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP S-allylcysteine results in increased expression of CYP3A2 protein CTD PMID:16000231 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions
ISO S-allylcysteine results in increased expression of FADD protein
S-allylcysteine promotes the reaction [FAS protein binds to FADD protein]; SB 203580 inhibits the reaction [S-allylcysteine promotes the reaction [FAS protein binds to FADD protein]]
CTD PMID:31067004 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of and results in increased activity of FAS protein]; S-allylcysteine inhibits the reaction [Diethylnitrosamine inhibits the reaction [FAS protein binds to FAS protein]]; S-allylcysteine inhibits the reaction [lead acetate affects the localization of and results in increased activity of FAS protein]
S-allylcysteine promotes the reaction [FAS protein binds to FADD protein]; S-allylcysteine promotes the reaction [FAS protein binds to FAS protein]; S-allylcysteine promotes the reaction [FAS protein binds to FASLG protein]; SB 203580 inhibits the reaction [S-allylcysteine promotes the reaction [FAS protein binds to FADD protein]]; SB 203580 inhibits the reaction [S-allylcysteine promotes the reaction [FAS protein binds to FASLG protein]]
CTD PMID:22033380, PMID:31067004 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
ISO S-allylcysteine promotes the reaction [FAS protein binds to FASLG protein]; SB 203580 inhibits the reaction [S-allylcysteine promotes the reaction [FAS protein binds to FASLG protein]]
S-allylcysteine results in increased expression of FASLG protein
CTD PMID:31067004 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO S-allylcysteine inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of FASN mRNA] CTD PMID:23465592 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GAL mRNA] CTD PMID:17182065 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GOT1 protein] CTD PMID:22033380 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO
EXP
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GPT protein]
S-allylcysteine inhibits the reaction [Cyclosporine results in increased activity of GPT protein]
CTD PMID:19391111, PMID:22033380 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP S-allylcysteine inhibits the reaction [Cyclosporine results in decreased activity of GSR protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein] CTD PMID:16757080, PMID:19391111 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GUSB mRNA] CTD PMID:17182065 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Jup junction plakoglobin increases expression ISO S-allylcysteine results in increased expression of JUP protein CTD PMID:17155983 NCBI chr10:88,280,517...88,307,451
Ensembl chr10:88,279,632...88,307,412
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]; S-allylcysteine inhibits the reaction [lead acetate results in increased activity of KCNN4 protein] CTD PMID:22033380 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Klk1 kallikrein 1 decreases expression ISO S-allylcysteine results in decreased expression of KLK3 protein CTD PMID:17155983 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP S-allylcysteine inhibits the reaction [Cyclosporine results in increased expression of MMP2 protein] CTD PMID:19391111 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP S-allylcysteine promotes the reaction [Potassium Dichromate results in increased expression of NFE2L2 protein] CTD PMID:18548744 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP S-allylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2]; S-allylcysteine inhibits the reaction [Cyclosporine results in increased expression of NOS2 protein] CTD PMID:16614485, PMID:19391111 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP S-allylcysteine inhibits the reaction [Isoproterenol results in decreased expression of OGDH mRNA] CTD PMID:17182065 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of PRDX2 protein]; [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]]; S-allylcysteine inhibits the reaction [lead acetate affects the localization of PRDX2 protein]; S-allylcysteine inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]] CTD PMID:22033380 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP S-allylcysteine inhibits the reaction [Cyclosporine results in increased expression of RELA protein] CTD PMID:19391111 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of SMPD1 protein]; S-allylcysteine inhibits the reaction [lead acetate results in increased activity of SMPD1 protein] CTD PMID:22033380 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
decreases expression
ISO dorsomorphin inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein]; S-allylcysteine inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of and affects the localization of SREBF1 protein]; S-allylcysteine inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 mRNA]; sirtinol inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein]; STO 609 inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein] CTD PMID:23465592 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP S-allylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:16614485 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases phosphorylation
ISO SB 203580 inhibits the reaction [S-allylcysteine results in increased phosphorylation of TP53 protein]
[Diethylnitrosamine co-treated with S-allylcysteine] results in increased phosphorylation of TRP53 protein
CTD PMID:31067004 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Upk2 uroplakin 2 multiple interactions ISO S-allylcysteine inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 mRNA]; S-allylcysteine inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 protein] CTD PMID:27234646 NCBI chr 8:48,772,906...48,774,898
Ensembl chr 8:48,772,906...48,774,898
JBrowse link
S-methyl-L-thiocitrulline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 multiple interactions EXP S-methylthiocitrulline inhibits the reaction [EDN1 protein results in increased abundance of Nitric Oxide] CTD PMID:16380457 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
decreases activity
EXP
ISO
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the abundance of Sodium
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine
CTD PMID:11006970, PMID:12511180 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] CTD PMID:17683483 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
S-methylcysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msra methionine sulfoxide reductase A multiple interactions ISO S-methylcysteine promotes the reaction [MSRA protein results in decreased susceptibility to chloramine-T] CTD PMID:19085252 NCBI chr15:47,488,333...47,800,662
Ensembl chr15:47,488,894...47,800,024
JBrowse link
G Pah phenylalanine hydroxylase increases oxidation ISO PAH protein results in increased oxidation of S-methylcysteine CTD PMID:19367645 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
Se-methyl-L-selenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
decreases expression
EXP Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Ar androgen receptor decreases expression ISO
EXP
selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA
CTD PMID:16637076, PMID:19025659 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP selenomethylselenocysteine results in decreased expression of ARNTL mRNA CTD PMID:19122877 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Banp Btg3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr19:54,766,441...54,843,795
Ensembl chr19:54,766,589...54,840,569
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of BCL2 mRNA
selenomethylselenocysteine results in decreased expression of BCL2 protein
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
CTD PMID:11396176, PMID:19360359 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bmf Bcl2 modifying factor multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; C646 compound inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF protein
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein
CTD PMID:25321483 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO selenomethylselenocysteine results in increased activity of CASP3 protein
selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]
CTD PMID:15318939, PMID:25321483 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]
CTD PMID:25321483 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
selenomethylselenocysteine results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein
CTD PMID:11396176, PMID:18855134, PMID:19276161 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein
CTD PMID:25321483 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176, PMID:19276161 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression EXP selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression EXP selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions