The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A racemate comprising equimolar amounts of (R)- and (S)-paliperidone palmitate. A long-acting injectable formulation of paliperidone (the major active metabolite of risperidone) that is used for treatment of schizophrenia.
ABCB1 gene polymorphism affects the abundance of Paliperidone Palmitate; ABCB1 protein affects the abundance of Paliperidone Palmitate ABCB1 protein results in increased transport of Paliperidone Palmitate Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin] Paliperidone Palmitate results in decreased activity of ABCB1 protein ABCB1A protein affects the susceptibility to Paliperidone Palmitate ABCB1A protein results in increased export of Paliperidone Palmitate ABCB1A protein results in increased transport of Paliperidone Palmitate Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of Paliperidone Palmitate]
Paliperidone Palmitate results in increased expression of FADS2 mRNA [Paliperidone Palmitate results in increased expression of FADS2 mRNA] which results in increased abundance of Fatty Acids, Unsaturated
[Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein
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