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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phospholipid biosynthesis inhibitor
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Accession:CHEBI:83741 term browser browse the term
Definition:Any compound that inhibits the biosynthesis of any phospholipid.
Synonyms:related_synonym: phospholipid biosynthesis inhibitors



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edifenphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO edifenphos results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
iprobenfos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO O,O-diisopropyl-S-benzylthiophosphate binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO O,O-diisopropyl-S-benzylthiophosphate results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
isoprothiolane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO isoprothiolane results in increased expression of CYP3A4 mRNA CTD PMID:17293382 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO isoprothiolane binds to and results in increased activity of ESR1 protein
isoprothiolane results in decreased expression of ESR1 protein
CTD PMID:17904202 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO isoprothiolane binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pgr progesterone receptor increases expression ISO isoprothiolane results in increased expression of PGR mRNA CTD PMID:17904202 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO isoprothiolane results in increased expression of TFF1 mRNA CTD PMID:17904202 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
pyrazophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO pyrazophos metabolite results in decreased activity of ACHE protein; pyrazophos results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19730
    role 19703
      biological role 19701
        biochemical role 19414
          phospholipid biosynthesis inhibitor 7
            edifenphos 1
            ethyl 2-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate + 1
            iprobenfos 2
            isoprothiolane + 5
            pyrazophos 1
paths to the root