Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pralidoxime
go back to main search page
Accession:CHEBI:8354 term browser browse the term
Definition:A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2.
Synonyms:exact_synonym: 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium
 related_synonym: 2-PAM;   Formula=C7H9N2O;   InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1;   InChIKey=JBKPUQTUERUYQE-UHFFFAOYSA-O;   Pralidoximum;   SMILES=C[n+]1ccccc1\\C=N\\O
 xref: CAS:6735-59-7;   DrugBank:DB00733;   Drug_Central:2231;   HMDB:HMDB0014871;   KEGG:C07400;   LINCS:LSM-5708
 xref_mesh: MESH:C028797
 xref: PMID:24625936;   Reaxys:1526531;   Wikipedia:Pralidoxime


show annotations for term's descendants           Sort by:
pralidoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein] CTD PMID:20370537 PMID:20971170 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605 		JBrowse link
G MAOA monoamine oxidase A decreases activity EXP pralidoxime results in decreased activity of MAOA protein CTD PMID:21195145 NCBI chr  X:38,930,452...39,006,220 JBrowse link
G MAOB monoamine oxidase B decreases activity EXP pralidoxime results in decreased activity of MAOB protein CTD PMID:21195145 NCBI chr  X:39,025,973...39,144,389
Ensembl chr  X:39,025,970...39,144,345 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5151
    role 5118
      biological role 5118
        biochemical role 5042
          enzyme reactivator 3
            cholinesterase reactivator 3
              pralidoxime 3
                pralidoxime chloride 0
                pralidoxime iodide 0
                pralidoxime mesylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5151
    subatomic particle 5142
      composite particle 5142
        hadron 5142
          baryon 5142
            nucleon 5142
              atomic nucleus 5142
                atom 5142
                  main group element atom 5115
                    p-block element atom 5112
                      carbon group element atom 5030
                        carbon group molecular entity 5030
                          organic molecular entity 5029
                            organic ion 109
                              organic cation 92
                                pyridinium ion 3
                                  pralidoxime 3
                                    pralidoxime chloride 0
                                    pralidoxime iodide 0
                                    pralidoxime mesylate 0
paths to the root