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ONTOLOGY REPORT - ANNOTATIONS


Term:1-benzylpiperazine
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Accession:CHEBI:83537 term browser browse the term
Definition:A tertiary amino compound that is piperazine substituted by a benzyl group at position 1. It is a serotonergic agonist used as a recreational drug.
Synonyms:related_synonym: BZP;   Benzylpiperazine;   Formula=C11H16N2;   InChI=1S/C11H16N2/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13/h1-5,12H,6-10H2;   InChIKey=IQXXEPZFOOTTBA-UHFFFAOYSA-N;   N-Benzylpiperazine;   SMILES=C(N1CCNCC1)c1ccccc1
 alt_id: MESH:C461488
 xref: CAS:2759-28-6
 xref_mesh: MESH:C006737
 xref: PMID:23685794;   PMID:24486525;   Reaxys:141624;   Wikipedia:Benzylpiperazine


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1-benzylpiperazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aass aminoadipate-semialdehyde synthase JBrowse link 6 23,072,173 23,132,986 RGD:6480464
G Acat2 acetyl-Coenzyme A acetyltransferase 2 JBrowse link 17 12,943,042 12,960,725 RGD:6480464
G Acsl3 acyl-CoA synthetase long-chain family member 3 JBrowse link 1 78,657,825 78,707,743 RGD:6480464
G Acsm5 acyl-CoA synthetase medium-chain family member 5 JBrowse link 7 119,526,131 119,543,360 RGD:6480464
G B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 JBrowse link 4 40,804,602 40,853,984 RGD:6480464
G Bbox1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase) JBrowse link 2 110,264,056 110,314,813 RGD:6480464
G Bhmt betaine-homocysteine methyltransferase JBrowse link 13 93,616,891 93,637,758 RGD:6480464
G Bhmt2 betaine-homocysteine methyltransferase 2 JBrowse link 13 93,656,097 93,674,302 RGD:6480464
G Cables1 CDK5 and Abl enzyme substrate 1 JBrowse link 18 11,839,274 11,945,627 RGD:6480464
G Csrp3 cysteine and glycine-rich protein 3 JBrowse link 7 48,830,398 48,848,051 RGD:6480464
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 JBrowse link 7 26,931,631 26,939,413 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 7 140,763,819 140,774,990 RGD:6480464
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B JBrowse link 4 115,411,624 115,439,034 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 5 4,080,674 4,104,697 RGD:6480464
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 JBrowse link 9 121,914,356 121,916,305 RGD:6480464
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 3 118,562,109 119,432,924 RGD:6480464
G Dpysl2 dihydropyrimidinase-like 2 JBrowse link 14 66,802,864 66,911,041 RGD:6480464
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 JBrowse link 9 25,481,513 25,604,110 RGD:6480464
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase JBrowse link 16 21,761,285 21,787,834 RGD:6480464
G Fads1 fatty acid desaturase 1 JBrowse link 19 10,182,877 10,196,874 RGD:6480464
G Fasn fatty acid synthase JBrowse link 11 120,805,958 120,825,166 RGD:6480464
G Fbp1 fructose bisphosphatase 1 JBrowse link 13 62,864,753 62,888,298 RGD:6480464
G Fdft1 farnesyl diphosphate farnesyl transferase 1 JBrowse link 14 63,145,150 63,181,687 RGD:6480464
G Fdps farnesyl diphosphate synthetase JBrowse link 3 89,093,588 89,101,967 RGD:6480464
G Flcn folliculin JBrowse link 11 59,791,408 59,810,039 RGD:6480464
G Ftcd formiminotransferase cyclodeaminase JBrowse link 10 76,575,648 76,590,338 RGD:6480464
G G6pc glucose-6-phosphatase, catalytic JBrowse link 11 101,367,716 101,377,903 RGD:6480464
G Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 JBrowse link 11 42,130,939 42,183,066 RGD:6480464
G Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 JBrowse link 11 42,419,515 42,632,591 RGD:6480464
G Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 JBrowse link 11 41,910,190 42,000,857 RGD:6480464
G Gpnmb glycoprotein (transmembrane) nmb JBrowse link 6 49,036,518 49,058,182 RGD:6480464
G Gys2 glycogen synthase 2 JBrowse link 6 142,422,612 142,473,130 RGD:6480464
G Hao2 hydroxyacid oxidase 2 JBrowse link 3 98,874,519 98,895,376 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase JBrowse link 13 96,648,962 96,670,936 RGD:6480464
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 JBrowse link 13 119,690,351 119,708,260 RGD:6480464
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 JBrowse link 3 98,280,431 98,310,738 RGD:6480464
G Idi1 isopentenyl-diphosphate delta isomerase JBrowse link 13 8,885,606 8,892,396 RGD:6480464
G Il1r2 interleukin 1 receptor, type II JBrowse link 1 40,084,692 40,125,230 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 5 28,071,412 28,078,662 RGD:6480464
G Kynu kynureninase JBrowse link 2 43,555,258 43,683,048 RGD:6480464
G Mcm6 minichromosome maintenance complex component 6 JBrowse link 1 128,331,575 128,359,705 RGD:6480464
G Mdh1 malate dehydrogenase 1, NAD (soluble) JBrowse link 11 21,556,692 21,571,934 RGD:6480464
G Msmo1 methylsterol monoxygenase 1 JBrowse link 8 64,718,123 64,733,578 RGD:6480464
G Ndrg1 N-myc downstream regulated gene 1 JBrowse link 15 66,929,318 66,969,641 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 1 171,213,934 171,218,845 RGD:6480464
G Nrg1 neuregulin 1 JBrowse link 8 31,807,452 32,891,609 RGD:6480464
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 4 106,442,334 106,464,325 RGD:6480464
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 8 104,591,472 104,599,026 RGD:6480464
G Pea15a phosphoprotein enriched in astrocytes 15A JBrowse link 1 172,196,728 172,206,804 RGD:6480464
G Pgr progesterone receptor JBrowse link 9 8,898,900 8,968,611 RGD:6480464
G Rab30 RAB30, member RAS oncogene family JBrowse link 7 92,741,637 92,844,535 RGD:6480464
G Rab32 RAB32, member RAS oncogene family JBrowse link 10 10,545,039 10,558,207 RGD:6480464
G Rhoq ras homolog family member Q JBrowse link 17 86,963,111 87,000,069 RGD:6480464
G Rnf145 ring finger protein 145 JBrowse link 11 44,518,793 44,565,520 RGD:6480464
G Rragd Ras-related GTP binding D JBrowse link 4 32,982,998 33,022,180 RGD:6480464
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 JBrowse link 12 80,953,185 80,968,705 RGD:6480464
G Slc38a7 solute carrier family 38, member 7 JBrowse link 8 95,835,920 95,853,577 RGD:6480464
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 JBrowse link 1 46,807,544 46,925,776 RGD:6480464
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 JBrowse link 6 91,684,048 91,759,063 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 6 141,805,438 141,856,284 RGD:6480464
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 JBrowse link 12 87,305,058 87,388,355 RGD:6480464
G Sqle squalene epoxidase JBrowse link 15 59,315,092 59,331,193 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 11 60,199,084 60,224,186 RGD:6480464
G Stard4 StAR-related lipid transfer (START) domain containing 4 JBrowse link 18 33,199,138 33,213,862 RGD:6480464
G Stk10 serine/threonine kinase 10 JBrowse link 11 32,533,266 32,624,595 RGD:6480464
G Stx3 syntaxin 3 JBrowse link 19 11,775,118 11,821,569 RGD:6480464
G Tecpr1 tectonin beta-propeller repeat containing 1 JBrowse link 5 144,194,442 144,223,615 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 17 31,161,395 31,165,060 RGD:6480464
G Tm4sf4 transmembrane 4 superfamily member 4 JBrowse link 3 57,425,410 57,441,677 RGD:6480464
G Trim59 tripartite motif-containing 59 JBrowse link 3 69,035,292 69,044,742 RGD:6480464
G Ttc36 tetratricopeptide repeat domain 36 JBrowse link 9 44,799,400 44,802,951 RGD:6480464
G Urad ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase JBrowse link 5 147,314,984 147,322,440 RGD:6480464
G Usp2 ubiquitin specific peptidase 2 JBrowse link 9 44,067,021 44,095,627 RGD:6480464
G Wfdc2 WAP four-disulfide core domain 2 JBrowse link 2 164,562,715 164,568,510 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21272
    role 21256
      biological role 21254
        xenobiotic 18901
          1-benzylpiperazine 74
Path 2
Term Annotations click to browse term
  CHEBI ontology 21272
    subatomic particle 21268
      composite particle 21268
        hadron 21268
          baryon 21268
            nucleon 21268
              atomic nucleus 21268
                atom 21268
                  main group element atom 21138
                    main group molecular entity 21138
                      s-block molecular entity 20611
                        hydrogen molecular entity 20523
                          hydrides 19496
                            inorganic hydride 17600
                              pnictogen hydride 17551
                                nitrogen hydride 17367
                                  azane 17236
                                    ammonia 17235
                                      organic amino compound 17234
                                        tertiary amino compound 8713
                                          N-alkylpiperazine 3050
                                            1-benzylpiperazine 74
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.