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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-benzylpiperazine
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Accession:CHEBI:83537 term browser browse the term
Definition:A tertiary amino compound that is piperazine substituted by a benzyl group at position 1. It is a serotonergic agonist used as a recreational drug.
Synonyms:related_synonym: BZP;   Benzylpiperazine;   Formula=C11H16N2;   InChI=1S/C11H16N2/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13/h1-5,12H,6-10H2;   InChIKey=IQXXEPZFOOTTBA-UHFFFAOYSA-N;   N-Benzylpiperazine;   SMILES=C(N1CCNCC1)c1ccccc1
 alt_id: MESH:C461488
 xref: CAS:2759-28-6
 xref_mesh: MESH:C006737
 xref: PMID:23685794;   PMID:24486525;   Reaxys:141624;   Wikipedia:Benzylpiperazine


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1-benzylpiperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase decreases expression EXP N-benzylpiperazine results in decreased expression of AASS mRNA CTD PMID:26821219 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP N-benzylpiperazine results in increased expression of ACAT2 mRNA CTD PMID:26821219 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP N-benzylpiperazine results in increased expression of ACSL3 mRNA CTD PMID:26821219 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acsm5 acyl-CoA synthetase medium-chain family member 5 decreases expression EXP N-benzylpiperazine results in decreased expression of ACSM5 mRNA CTD PMID:26821219 NCBI chr 1:189,240,955...189,270,422
Ensembl chr 1:189,233,141...189,272,172
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression EXP N-benzylpiperazine results in increased expression of B4GALT1 mRNA CTD PMID:26821219 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP N-benzylpiperazine results in decreased expression of BBOX1 mRNA CTD PMID:26821219 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP N-benzylpiperazine results in decreased expression of BHMT mRNA CTD PMID:26821219 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 decreases expression EXP N-benzylpiperazine results in decreased expression of BHMT2 mRNA CTD PMID:26821219 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 increases expression EXP N-benzylpiperazine results in increased expression of CABLES1 mRNA CTD PMID:26821219 NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP N-benzylpiperazine results in increased expression of CSRP3 mRNA CTD PMID:26821219 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression EXP N-benzylpiperazine results in decreased expression of CYP2A1 mRNA CTD PMID:26821219 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression EXP N-benzylpiperazine results in decreased expression of CYP2E1 mRNA CTD PMID:26821219 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP N-benzylpiperazine results in decreased expression of CYP4A1 mRNA CTD PMID:26821219 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP N-benzylpiperazine results in decreased expression of CYP4A3 mRNA CTD PMID:26821219 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 decreases expression EXP N-benzylpiperazine results in decreased expression of CYP4F4 mRNA CTD PMID:26821219 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP N-benzylpiperazine results in increased expression of CYP51 mRNA CTD PMID:26821219 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression EXP N-benzylpiperazine results in decreased expression of CYP8B1 mRNA CTD PMID:26821219 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP N-benzylpiperazine results in decreased expression of DPYD mRNA CTD PMID:26821219 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression EXP N-benzylpiperazine results in increased expression of DPYSL2 mRNA CTD PMID:26821219 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression EXP N-benzylpiperazine results in increased expression of EEPD1 mRNA CTD PMID:26821219 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression EXP N-benzylpiperazine results in decreased expression of EHHADH mRNA CTD PMID:26821219 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression EXP N-benzylpiperazine results in increased expression of FADS1 mRNA CTD PMID:26821219 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fasn fatty acid synthase increases expression EXP N-benzylpiperazine results in increased expression of FASN mRNA CTD PMID:26821219 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression EXP N-benzylpiperazine results in decreased expression of FBP1 mRNA CTD PMID:26821219 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP N-benzylpiperazine results in increased expression of FDFT1 mRNA CTD PMID:26821219 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP N-benzylpiperazine results in increased expression of FDPS mRNA CTD PMID:26821219 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Flcn folliculin increases expression EXP N-benzylpiperazine results in increased expression of FLCN mRNA CTD PMID:26821219 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase decreases expression EXP N-benzylpiperazine results in decreased expression of FTCD mRNA CTD PMID:26821219 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G G6pc glucose-6-phosphatase, catalytic subunit decreases expression EXP N-benzylpiperazine results in decreased expression of G6PC mRNA CTD PMID:26821219 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO 1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:26344803 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO 1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:26344803 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO 1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:26344803 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP N-benzylpiperazine results in increased expression of GPNMB mRNA CTD PMID:26821219 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gys2 glycogen synthase 2 decreases expression EXP N-benzylpiperazine results in decreased expression of GYS2 mRNA CTD PMID:26821219 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP N-benzylpiperazine results in decreased expression of HAO2 mRNA CTD PMID:26821219 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP N-benzylpiperazine results in increased expression of HMGCR mRNA CTD PMID:26821219 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP N-benzylpiperazine results in increased expression of HMGCS1 mRNA CTD PMID:26821219 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP N-benzylpiperazine results in decreased expression of HMGCS2 mRNA CTD PMID:26821219 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP N-benzylpiperazine results in increased expression of IDI1 mRNA CTD PMID:26821219 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression EXP N-benzylpiperazine results in increased expression of IL1R2 mRNA CTD PMID:26821219 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Insig1 insulin induced gene 1 increases expression EXP N-benzylpiperazine results in increased expression of INSIG1 mRNA CTD PMID:26821219 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Kynu kynureninase decreases expression EXP N-benzylpiperazine results in decreased expression of KYNU mRNA CTD PMID:26821219 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP N-benzylpiperazine results in increased expression of MCM6 mRNA CTD PMID:26821219 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression EXP N-benzylpiperazine results in decreased expression of MDH1 mRNA CTD PMID:26821219 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression EXP N-benzylpiperazine results in increased expression of MSMO1 mRNA CTD PMID:26821219 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression EXP N-benzylpiperazine results in increased expression of NDRG1 mRNA CTD PMID:26821219 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression EXP N-benzylpiperazine results in decreased expression of NR1I3 mRNA CTD PMID:26821219 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP N-benzylpiperazine results in increased expression of NRG1 mRNA CTD PMID:26821219 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression EXP N-benzylpiperazine results in increased expression of PCSK9 mRNA CTD PMID:26821219 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 increases expression EXP N-benzylpiperazine results in increased expression of PDP2 mRNA CTD PMID:26821219 NCBI chr19:597,427...601,556
Ensembl chr19:597,427...601,469
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression EXP N-benzylpiperazine results in increased expression of PEA15 mRNA CTD PMID:26821219 NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
JBrowse link
G Pgr progesterone receptor increases expression ISO 1-benzylpiperazine results in increased expression of PGR mRNA CTD PMID:23026265 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP N-benzylpiperazine results in increased expression of RAB30 mRNA CTD PMID:26821219 NCBI chr 1:157,573,344...157,667,973
Ensembl chr 1:157,573,324...157,660,008
JBrowse link
G Rab32 RAB32, member RAS oncogene family increases expression EXP N-benzylpiperazine results in increased expression of RAB32 mRNA CTD PMID:26821219 NCBI chr 1:4,638,663...4,653,220
Ensembl chr 1:4,637,491...4,653,210
JBrowse link
G Rhoq ras homolog family member Q increases expression EXP N-benzylpiperazine results in increased expression of RHOQ mRNA CTD PMID:26821219 NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
JBrowse link
G Rnf145 ring finger protein 145 increases expression EXP N-benzylpiperazine results in increased expression of RNF145 mRNA CTD PMID:26821219 NCBI chr10:30,169,147...30,207,505
Ensembl chr10:30,169,257...30,207,498
JBrowse link
G Rragd Ras-related GTP binding D increases expression EXP N-benzylpiperazine results in increased expression of RRAGD mRNA CTD PMID:26821219 NCBI chr 5:48,224,994...48,260,691
Ensembl chr 5:48,224,994...48,260,685
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP N-benzylpiperazine results in decreased expression of SLC10A1 mRNA CTD PMID:26821219 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc38a7 solute carrier family 38, member 7 increases expression EXP N-benzylpiperazine results in increased expression of SLC38A7 mRNA CTD PMID:26821219 NCBI chr19:9,622,594...9,638,221
Ensembl chr19:9,622,611...9,638,222
JBrowse link
G Slc39a10 solute carrier family 39 member 10 increases expression EXP N-benzylpiperazine results in increased expression of SLC39A10 mRNA CTD PMID:26821219 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP N-benzylpiperazine results in increased expression of SLC6A6 mRNA CTD PMID:26821219 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP N-benzylpiperazine results in decreased expression of SLCO1A2 mRNA CTD PMID:26821219 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 increases expression EXP N-benzylpiperazine results in increased expression of SPTLC2 mRNA CTD PMID:26821219 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sqle squalene epoxidase increases expression EXP N-benzylpiperazine results in increased expression of SQLE mRNA CTD PMID:26821219 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP N-benzylpiperazine results in increased expression of SREBF1 mRNA CTD PMID:26821219 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 increases expression EXP N-benzylpiperazine results in increased expression of STARD4 mRNA CTD PMID:26821219 NCBI chr18:25,982,210...25,997,555
Ensembl chr18:25,984,638...25,997,555
JBrowse link
G Stk10 serine/threonine kinase 10 increases expression EXP N-benzylpiperazine results in increased expression of STK10 mRNA CTD PMID:26821219 NCBI chr10:17,420,964...17,521,810
Ensembl chr10:17,421,075...17,519,706
JBrowse link
G Stx3 syntaxin 3 increases expression EXP N-benzylpiperazine results in increased expression of STX3 mRNA CTD PMID:26821219 NCBI chr 1:228,137,781...228,195,004
Ensembl chr 1:228,149,867...228,194,977
JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 increases expression EXP N-benzylpiperazine results in increased expression of TECPR1 mRNA CTD PMID:26821219 NCBI chr12:12,374,132...12,403,382
Ensembl chr12:12,374,790...12,402,552
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 1-benzylpiperazine results in increased expression of TFF1 mRNA CTD PMID:23026265 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 decreases expression EXP N-benzylpiperazine results in decreased expression of TM4SF4 mRNA CTD PMID:26821219 NCBI chr 2:147,532,032...147,547,254
Ensembl chr 2:147,496,229...147,547,252
JBrowse link
G Trim59 tripartite motif-containing 59 increases expression EXP N-benzylpiperazine results in increased expression of TRIM59 mRNA CTD PMID:26821219 NCBI chr 2:165,629,903...165,641,751
Ensembl chr 2:165,629,918...165,641,573
JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 decreases expression EXP N-benzylpiperazine results in decreased expression of TTC36 mRNA CTD PMID:26821219 NCBI chr 8:49,106,374...49,109,981
Ensembl chr 8:49,106,374...49,109,981
JBrowse link
G Urad ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase decreases expression EXP N-benzylpiperazine results in decreased expression of URAD mRNA CTD PMID:26821219 NCBI chr12:9,446,808...9,456,777
Ensembl chr12:9,446,940...9,455,673
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression EXP N-benzylpiperazine results in decreased expression of USP2 mRNA CTD PMID:26821219 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Wfdc2 WAP four-disulfide core domain 2 increases expression EXP N-benzylpiperazine results in increased expression of WFDC2 mRNA CTD PMID:26821219 NCBI chr 3:161,018,497...161,045,469
Ensembl chr 3:161,018,511...161,024,209
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          1-benzylpiperazine 76
Path 2
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  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        tertiary amino compound 8630
                                          N-alkylpiperazine 3075
                                            1-benzylpiperazine 76
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.