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ONTOLOGY REPORT - ANNOTATIONS


Term:moclobemide
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Accession:CHEBI:83531 term browser browse the term
Definition:A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Synonyms:exact_synonym: 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide
 related_synonym: Formula=C13H17ClN2O2;   InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17);   InChIKey=YHXISWVBGDMDLQ-UHFFFAOYSA-N;   SMILES=Clc1ccc(cc1)C(=O)NCCN1CCOCC1;   moclobemida;   moclobemidum
 xref: CAS:71320-77-9 "ChemIDplus";   CAS:71320-77-9 "KEGG DRUG";   CAS:71320-77-9 "NIST Chemistry WebBook";   DrugBank:DB01171;   Drug_Central:1825 "DrugCentral";   HMDB:HMDB0015302;   KEGG:D02561;   LINCS:LSM-5247
 xref_mesh: MESH:D020912
 xref: PMID:23616181 "Europe PMC";   PMID:24859491 "Europe PMC";   PMID:24863864 "Europe PMC";   PMID:25335956 "Europe PMC";   Reaxys:530974 "Reaxys"


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moclobemide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19614
    role 19557
      biological role 19550
        xenobiotic 18180
          moclobemide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    p-block element atom 19489
                      carbon group element atom 19362
                        carbon atom 19354
                          organic molecular entity 19354
                            organic group 18313
                              organic divalent group 18303
                                organodiyl group 18303
                                  carbonyl group 18188
                                    carbonyl compound 18188
                                      carboxylic acid 17853
                                        carboacyl group 16940
                                          univalent carboacyl group 16940
                                            carbamoyl group 16620
                                              carboxamide 16620
                                                monocarboxylic acid amide 13184
                                                  arenecarboxamide 6403
                                                    benzamides 6403
                                                      moclobemide 2
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