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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:83531 term browser browse the term
Definition:A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Synonyms:exact_synonym: 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide
 related_synonym: Formula=C13H17ClN2O2;   InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17);   InChIKey=YHXISWVBGDMDLQ-UHFFFAOYSA-N;   SMILES=Clc1ccc(cc1)C(=O)NCCN1CCOCC1;   moclobemida;   moclobemidum
 xref: CAS:71320-77-9;   DrugBank:DB01171;   Drug_Central:1825;   HMDB:HMDB0015302;   KEGG:D02561;   LINCS:LSM-5247
 xref_mesh: MESH:D020912
 xref: PMID:23616181;   PMID:24859491;   PMID:24863864;   PMID:25335956;   Reaxys:530974

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moclobemide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases metabolic processing ISO CYP2C19 protein results in increased metabolism of Moclobemide CTD PMID:12464242 NCBI chr 1:237,938,521...237,976,238 JBrowse link
G Maoa monoamine oxidase A decreases activity
multiple interactions
Moclobemide results in decreased activity of MAOA protein
Moclobemide inhibits the reaction [MAOA protein results in decreased amination of Serotonin]
CTD PMID:15178694 PMID:15545290 PMID:21923181 PMID:23943324 PMID:26721607 NCBI chr  X:6,032,172...6,098,308 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    role 19708
      biological role 19708
        xenobiotic 18395
          moclobemide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18611
                              organic divalent group 18602
                                organodiyl group 18602
                                  carbonyl group 18519
                                    carbonyl compound 18519
                                      carboxylic acid 18195
                                        carboacyl group 17423
                                          univalent carboacyl group 17423
                                            carbamoyl group 17230
                                              carboxamide 17230
                                                monocarboxylic acid amide 14854
                                                  arenecarboxamide 6591
                                                    benzamides 6591
                                                      moclobemide 2
paths to the root