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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:83518 term browser browse the term
Definition:A 1,2-thiazole that is 1,2-thiazol-3(2H)-one substituted by chloro groups at positions 4 and 5 and an octyl group at position 2. It is used as a fungicide.
Synonyms:exact_synonym: 4,5-dichloro-2-octyl-1,2-thiazol-3(2H)-one
 related_synonym: DCOIT;   Formula=C11H17Cl2NOS;   InChI=1S/C11H17Cl2NOS/c1-2-3-4-5-6-7-8-14-11(15)9(12)10(13)16-14/h2-8H2,1H3;   InChIKey=PORQOHRXAJJKGK-UHFFFAOYSA-N;   Kathon 930;   SMILES=CCCCCCCCn1sc(Cl)c(Cl)c1=O;   dichlorooctylisothiazolinone
 xref: CAS:64359-81-5
 xref_mesh: MESH:C080469
 xref: PMID:24850171;   Patent:NZ524752;   Patent:US2010256204;   Reaxys:1110842

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4,5-dichloro-2-n-octyl-3(2H)-isothiazolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Kathon 930 results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Kathon 930 results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Kathon 930 results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Kathon 930 inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      biological role 19873
        xenobiotic 18765
          4,5-dichloro-2-n-octyl-3(2H)-isothiazolone 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    p-block element atom 19845
                      carbon group element atom 19792
                        carbon atom 19787
                          organic molecular entity 19787
                            organic molecule 19744
                              organic cyclic compound 19549
                                organic heterocyclic compound 18888
                                  heteroarene 17153
                                    monocyclic heteroarene 14802
                                      azole 14287
                                        thiazoles 1792
                                          1,2-thiazoles 686
                                            4,5-dichloro-2-n-octyl-3(2H)-isothiazolone 4
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