CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: N'-(2,4-dimethylphenyl)-N-methylformamidine
Accession: CHEBI:83515
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Definition: A member of the class of formamidines that is N-methylimidoformamide in which the hydrogen attached to the nitrogen atom has been replaced by a 2,4-dimethylphenyl group. It is a metabolite of the insecticide amitraz.
Synonyms: exact_synonym: N-(2,4-dimethylphenyl)-N'-methylimidoformamide
related_synonym: Formula=C10H14N2; InChI=1S/C10H14N2/c1-8-4-5-10(9(2)6-8)12-7-11-3/h4-7H,1-3H3,(H,11,12); InChIKey=JIIOLEGNERQDIP-UHFFFAOYSA-N; N'-(2,4-Xylyl)-N-methylformamidine; SMILES=CN=CNc1ccc(C)cc1C
xref: CAS:33089-74-6
xref_mesh: MESH:C025699
xref: Reaxys:15189560
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Cat
catalase
decreases expression multiple interactions
EXP
U 40481 results in decreased expression of CAT protein KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]
CTD
PMID:31029719
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP1A1 protein
CTD
PMID:31029719
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
U 40481 results in increased expression of CYP1A2 protein
CTD
PMID:31029719
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP2B1 protein
CTD
PMID:31029719
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
U 40481 results in increased expression of CYP2B2 protein
CTD
PMID:31029719
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP2E1 protein
CTD
PMID:31029719
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP3A23-3A1 protein
CTD
PMID:31029719
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Gcg
glucagon
increases secretion
EXP
U 40481 results in increased secretion of GCG protein
CTD
PMID:10582558
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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Keap1
Kelch-like ECH-associated protein 1
increases expression multiple interactions
EXP
U 40481 results in increased expression of KEAP1 protein KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein]
CTD
PMID:31029719
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions decreases expression
EXP
KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein]
CTD
PMID:31029719
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression multiple interactions
EXP
U 40481 results in decreased expression of NQO1 protein KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]
CTD
PMID:31029719
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Sod1
superoxide dismutase 1
multiple interactions decreases expression
EXP
KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein]
CTD
PMID:31029719
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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