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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N'-(2,4-dimethylphenyl)-N-methylformamidine
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Accession:CHEBI:83515 term browser browse the term
Definition:A member of the class of formamidines that is N-methylimidoformamide in which the hydrogen attached to the nitrogen atom has been replaced by a 2,4-dimethylphenyl group. It is a metabolite of the insecticide amitraz.
Synonyms:exact_synonym: N-(2,4-dimethylphenyl)-N'-methylimidoformamide
 related_synonym: Formula=C10H14N2;   InChI=1S/C10H14N2/c1-8-4-5-10(9(2)6-8)12-7-11-3/h4-7H,1-3H3,(H,11,12);   InChIKey=JIIOLEGNERQDIP-UHFFFAOYSA-N;   N'-(2,4-Xylyl)-N-methylformamidine;   SMILES=CN=CNc1ccc(C)cc1C
 xref: CAS:33089-74-6
 xref_mesh: MESH:C025699
 xref: Reaxys:15189560



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N'-(2,4-dimethylphenyl)-N-methylformamidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases expression
multiple interactions
EXP U 40481 results in decreased expression of CAT protein
KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]
CTD PMID:31029719 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP1A1 protein CTD PMID:31029719 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP U 40481 results in increased expression of CYP1A2 protein CTD PMID:31029719 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP2B1 protein CTD PMID:31029719 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP U 40481 results in increased expression of CYP2B2 protein CTD PMID:31029719 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP2E1 protein CTD PMID:31029719 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP3A23-3A1 protein CTD PMID:31029719 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Gcg glucagon increases secretion EXP U 40481 results in increased secretion of GCG protein CTD PMID:10582558 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression
multiple interactions
EXP U 40481 results in increased expression of KEAP1 protein
KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein]
CTD PMID:31029719 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
EXP KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein] CTD PMID:31029719 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
EXP U 40481 results in decreased expression of NQO1 protein
KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]
CTD PMID:31029719 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression
EXP KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein] CTD PMID:31029719 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link

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  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            xenobiotic metabolite 15278
              marine xenobiotic metabolite 4100
                N'-(2,4-dimethylphenyl)-N-methylformamidine 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                carbocyclic compound 18616
                                  benzenoid aromatic compound 17993
                                    benzenes 17844
                                      N'-(2,4-dimethylphenyl)-N-methylformamidine 12
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