CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: N'-(2,4-dimethylphenyl)-N-methylformamidine
Accession: CHEBI:83515
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Definition: A member of the class of formamidines that is N-methylimidoformamide in which the hydrogen attached to the nitrogen atom has been replaced by a 2,4-dimethylphenyl group. It is a metabolite of the insecticide amitraz.
Synonyms: exact_synonym: N-(2,4-dimethylphenyl)-N'-methylimidoformamide
related_synonym: Formula=C10H14N2; InChI=1S/C10H14N2/c1-8-4-5-10(9(2)6-8)12-7-11-3/h4-7H,1-3H3,(H,11,12); InChIKey=JIIOLEGNERQDIP-UHFFFAOYSA-N; N'-(2,4-Xylyl)-N-methylformamidine; SMILES=CN=CNc1ccc(C)cc1C
xref: CAS:33089-74-6
xref_mesh: MESH:C025699
xref: Reaxys:15189560
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Cat
catalase
decreases expression multiple interactions
EXP
U 40481 results in decreased expression of CAT protein KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]
CTD
PMID:31029719
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP1A1 protein
CTD
PMID:31029719
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
U 40481 results in increased expression of CYP1A2 protein
CTD
PMID:31029719
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP2B1 protein
CTD
PMID:31029719
NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
U 40481 results in increased expression of CYP2B2 protein
CTD
PMID:31029719
NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP2E1 protein
CTD
PMID:31029719
NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
U 40481 results in increased expression of CYP3A23-3A1 protein
CTD
PMID:31029719
NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
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Gcg
glucagon
increases secretion
EXP
U 40481 results in increased secretion of GCG protein
CTD
PMID:10582558
NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
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Keap1
Kelch-like ECH-associated protein 1
increases expression multiple interactions
EXP
U 40481 results in increased expression of KEAP1 protein KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein]
CTD
PMID:31029719
NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
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Nfe2l2
nuclear factor, erythroid 2-like 2
multiple interactions decreases expression
EXP
KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein]
CTD
PMID:31029719
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression multiple interactions
EXP
U 40481 results in decreased expression of NQO1 protein KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]
CTD
PMID:31029719
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
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Sod1
superoxide dismutase 1
multiple interactions decreases expression
EXP
KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein]
CTD
PMID:31029719
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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