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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N'-(2,4-dimethylphenyl)-N-methylformamidine
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Accession:CHEBI:83515 term browser browse the term
Definition:A member of the class of formamidines that is N-methylimidoformamide in which the hydrogen attached to the nitrogen atom has been replaced by a 2,4-dimethylphenyl group. It is a metabolite of the insecticide amitraz.
Synonyms:exact_synonym: N-(2,4-dimethylphenyl)-N'-methylimidoformamide
 related_synonym: Formula=C10H14N2;   InChI=1S/C10H14N2/c1-8-4-5-10(9(2)6-8)12-7-11-3/h4-7H,1-3H3,(H,11,12);   InChIKey=JIIOLEGNERQDIP-UHFFFAOYSA-N;   N'-(2,4-Xylyl)-N-methylformamidine;   SMILES=CN=CNc1ccc(C)cc1C
 xref: CAS:33089-74-6
 xref_mesh: MESH:C025699
 xref: Reaxys:15189560

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N'-(2,4-dimethylphenyl)-N-methylformamidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases expression
multiple interactions		 EXP U 40481 results in decreased expression of CAT protein
KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]		 CTD PMID:31029719 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP1A1 protein CTD PMID:31029719 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP U 40481 results in increased expression of CYP1A2 protein CTD PMID:31029719 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP2B1 protein CTD PMID:31029719 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP U 40481 results in increased expression of CYP2B2 protein CTD PMID:31029719 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP2E1 protein CTD PMID:31029719 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP U 40481 results in increased expression of CYP3A23-3A1 protein CTD PMID:31029719 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136 		JBrowse link
G Gcg glucagon increases secretion EXP U 40481 results in increased secretion of GCG protein CTD PMID:10582558 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression
multiple interactions		 EXP U 40481 results in increased expression of KEAP1 protein
KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]; KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein]		 CTD PMID:31029719 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression		 EXP KEAP1 protein affects the reaction [U 40481 results in decreased expression of NFE2L2 protein] CTD PMID:31029719 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions		 EXP U 40481 results in decreased expression of NQO1 protein
KEAP1 protein affects the reaction [U 40481 results in decreased expression of NQO1 protein]		 CTD PMID:31029719 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression		 EXP KEAP1 protein affects the reaction [U 40481 results in decreased expression of SOD1 protein] CTD PMID:31029719 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        biochemical role 19360
          metabolite 19341
            xenobiotic metabolite 14259
              marine xenobiotic metabolite 3981
                N'-(2,4-dimethylphenyl)-N-methylformamidine 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic molecule 19586
                              organic cyclic compound 19395
                                carbocyclic compound 18305
                                  benzenoid aromatic compound 17344
                                    benzenes 17087
                                      N'-(2,4-dimethylphenyl)-N-methylformamidine 12
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