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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:neotame
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Accession:CHEBI:83503 term browser browse the term
Definition:A dipeptide composed of N-(3,3-dimethylbutyl)-L-aspartic acid and methyl L-phenylalanate units joined by a peptide linkage.
Synonyms:exact_synonym: methyl N-(3,3-dimethylbutyl)-L-alpha-aspartyl-L-phenylalaninate
 related_synonym: Formula=C20H30N2O5;   InChI=1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1;   InChIKey=HLIAVLHNDJUHFG-HOTGVXAUSA-N;   N-[N-(3,3-dimethylbutyl)-L-alpha-aspartyl]-L-phenylalanine methyl ester;   SMILES=COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C
 xref: CAS:165450-17-9;   HMDB:HMDB0034566
 xref_mesh: MESH:C404525
 xref: PMID:23595253;   PMID:24612793;   PMID:25216979;   Reaxys:8352678;   Wikipedia:Neotame


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neotame term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tas1r2 taste 1 receptor member 2 affects binding
multiple interactions
ISO neotame binds to [TAS1R2 protein binds to TAS1R3 protein]; neotame binds to TAS1R2 protein
neotame binds to and results in increased activity of TAS1R2 protein; neotame results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
CTD PMID:15353592 PMID:17168764 PMID:20173092 NCBI chr 5:151,909,648...151,925,345 JBrowse link
G Tas1r3 taste 1 receptor member 3 affects binding
multiple interactions
ISO neotame binds to [TAS1R2 protein binds to TAS1R3 protein]
neotame results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
CTD PMID:17168764 PMID:20173092 NCBI chr 5:166,469,589...166,472,742
Ensembl chr 5:166,469,589...166,472,742
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        xenobiotic 18452
          neotame 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        carboacyl group 17485
                                          univalent carboacyl group 17485
                                            carbamoyl group 17299
                                              carboxamide 17299
                                                peptide 9450
                                                  oligopeptide 1268
                                                    dipeptide 376
                                                      neotame 2
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