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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:neotame
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Accession:CHEBI:83503 term browser browse the term
Definition:A dipeptide composed of N-(3,3-dimethylbutyl)-L-aspartic acid and methyl L-phenylalanate units joined by a peptide linkage.
Synonyms:exact_synonym: methyl N-(3,3-dimethylbutyl)-L-alpha-aspartyl-L-phenylalaninate
 related_synonym: Formula=C20H30N2O5;   InChI=1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1;   InChIKey=HLIAVLHNDJUHFG-HOTGVXAUSA-N;   N-[N-(3,3-dimethylbutyl)-L-alpha-aspartyl]-L-phenylalanine methyl ester;   SMILES=COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C
 xref: CAS:165450-17-9;   HMDB:HMDB0034566
 xref_mesh: MESH:C404525
 xref: PMID:23595253;   PMID:24612793;   PMID:25216979;   Reaxys:8352678;   Wikipedia:Neotame


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neotame term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tas1r2 taste 1 receptor member 2 affects binding
multiple interactions
ISO neotame binds to [TAS1R2 protein binds to TAS1R3 protein]; neotame binds to TAS1R2 protein
neotame binds to and results in increased activity of TAS1R2 protein; neotame results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
CTD PMID:15353592, PMID:17168764, PMID:20173092 NCBI chr 5:158,119,894...158,135,733
Ensembl chr 5:158,042,587...158,135,733
JBrowse link
G Tas1r3 taste 1 receptor member 3 affects binding
multiple interactions
ISO neotame binds to [TAS1R2 protein binds to TAS1R3 protein]
neotame results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
CTD PMID:17168764, PMID:20173092 NCBI chr 5:173,307,325...173,312,950
Ensembl chr 5:173,308,870...173,312,023
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          neotame 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            carbamoyl group 17134
                                              carboxamide 17134
                                                peptide 9392
                                                  oligopeptide 1196
                                                    dipeptide 372
                                                      neotame 2
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