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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:perfluoroundecanoic acid
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Accession:CHEBI:83493 term browser browse the term
Definition:A fluoroalkanoic acid that is perfluorinated undecanoic acid.
Synonyms:exact_synonym: henicosafluoroundecanoic acid
 related_synonym: Formula=C11HF21O2;   InChI=1S/C11HF21O2/c12-2(13,1(33)34)3(14,15)4(16,17)5(18,19)6(20,21)7(22,23)8(24,25)9(26,27)10(28,29)11(30,31)32/h(H,33,34);   InChIKey=SIDINRCMMRKXGQ-UHFFFAOYSA-N;   SMILES=OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
 xref: CAS:2058-94-8
 xref_mesh: MESH:C101814
 xref: PMID:24418714;   PMID:24486970;   PMID:24952613;   Reaxys:2318888


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perfluoroundecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP perfluoroundecanoic acid results in decreased expression of A2M mRNA CTD PMID:23567314 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186 		JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 increases expression ISO perfluoroundecanoic acid results in increased expression of ABCA1 mRNA CTD PMID:35337807 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO perfluoroundecanoic acid results in increased expression of ACOT2 mRNA CTD PMID:35337807 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation ISO perfluoroundecanoic acid results in decreased phosphorylation of AKT1 protein CTD PMID:33549592 PMID:35143807 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt2 thymoma viral proto-oncogene 2 decreases phosphorylation ISO perfluoroundecanoic acid results in decreased phosphorylation of AKT2 protein CTD PMID:33549592 PMID:35143807 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluoroundecanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804 		JBrowse link
G Apoa2 apolipoprotein A-II affects expression ISO perfluoroundecanoic acid affects the expression of APOA2 mRNA CTD PMID:23567314 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apoa4 apolipoprotein A-IV affects expression ISO perfluoroundecanoic acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP perfluoroundecanoic acid results in increased expression of ATF3 mRNA CTD PMID:23567314 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon multiple interactions ISO [perfluoroundecanoic acid affects the methylation of ATP5F1E gene] which affects the expression of ATP5F1E mRNA CTD PMID:32653021 NCBI chr 2:174,302,868...174,305,894
Ensembl chr 2:174,302,865...174,305,898 		JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase decreases expression EXP perfluoroundecanoic acid results in decreased expression of BAAT mRNA CTD PMID:23567314 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557 		JBrowse link
G Bax BCL2-associated X protein increases expression ISO perfluoroundecanoic acid results in increased expression of BAX mRNA; perfluoroundecanoic acid results in increased expression of BAX protein CTD PMID:33549592 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO perfluoroundecanoic acid results in decreased expression of BCL2 protein CTD PMID:33549592 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase, type 2 increases expression ISO perfluoroundecanoic acid results in increased expression of BDH2 mRNA CTD PMID:35337807 NCBI chr 3:134,986,982...135,010,187
Ensembl chr 3:134,986,982...135,010,187 		JBrowse link
G Becn1 beclin 1, autophagy related increases expression ISO perfluoroundecanoic acid results in increased expression of BECN1 protein CTD PMID:33549592 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CCL20 protein CTD PMID:32916415 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Cd36 CD36 molecule decreases expression
increases uptake		 EXP
ISO		 perfluoroundecanoic acid results in decreased expression of CD36 mRNA
CD36 protein results in increased uptake of perfluoroundecanoic acid		 CTD PMID:23567314 PMID:35380827 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd40 CD40 antigen decreases expression ISO perfluoroundecanoic acid results in decreased expression of CD40 protein CTD PMID:32916415 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression ISO perfluoroundecanoic acid results in increased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) decreases expression ISO perfluoroundecanoic acid results in decreased expression of CSF1 protein CTD PMID:32916415 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Cstb cystatin B decreases expression ISO perfluoroundecanoic acid results in decreased expression of CSTB protein CTD PMID:32916415 NCBI chr10:78,261,504...78,263,456
Ensembl chr10:78,261,503...78,263,456 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CYP11A1 mRNA; perfluoroundecanoic acid results in decreased expression of CYP11A1 protein CTD PMID:33549592 PMID:35143807 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CYP17A1 mRNA; perfluoroundecanoic acid results in decreased expression of CYP17A1 protein CTD PMID:33549592 PMID:35143807 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases expression EXP perfluoroundecanoic acid results in decreased expression of CYP2B10 mRNA CTD PMID:23567314 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 decreases expression EXP perfluoroundecanoic acid results in decreased expression of CYP3A11 mRNA CTD PMID:23567314 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP perfluoroundecanoic acid results in increased expression of DDIT3 mRNA CTD PMID:23567314 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dhh desert hedgehog decreases expression ISO perfluoroundecanoic acid results in decreased expression of DHH mRNA; perfluoroundecanoic acid results in decreased expression of DHH protein CTD PMID:33549592 NCBI chr15:98,779,496...98,796,443
Ensembl chr15:98,789,033...98,796,421 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of DKK1 protein CTD PMID:32916415 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in increased expression of DRD2 mRNA CTD PMID:34371090 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477 		JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase increases expression ISO perfluoroundecanoic acid results in increased expression of EHHADH mRNA CTD PMID:35337807 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases activity ISO perfluoroundecanoic acid results in increased activity of ESR1 protein CTD PMID:21163906 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fabp1 fatty acid binding protein 1, liver decreases expression ISO perfluoroundecanoic acid results in decreased expression of FABP1 mRNA CTD PMID:35337807 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO perfluoroundecanoic acid results in decreased expression of FAS protein CTD PMID:32916415 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasn fatty acid synthase increases expression ISO perfluoroundecanoic acid results in increased expression of FASN mRNA CTD PMID:35337807 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027 		JBrowse link
G Fgf23 fibroblast growth factor 23 decreases expression ISO perfluoroundecanoic acid results in decreased expression of FGF23 protein CTD PMID:32916415 NCBI chr 6:127,049,865...127,059,257
Ensembl chr 6:127,049,865...127,058,371 		JBrowse link
G Fshb follicle stimulating hormone beta decreases expression
decreases secretion		 ISO perfluoroundecanoic acid results in decreased expression of FSHB mRNA
perfluoroundecanoic acid results in decreased secretion of FSHB protein		 CTD PMID:33549592 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO perfluoroundecanoic acid results in decreased expression of FSHR mRNA; perfluoroundecanoic acid results in decreased expression of FSHR protein CTD PMID:33549592 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta increases expression EXP perfluoroundecanoic acid results in increased expression of GADD45B mRNA CTD PMID:23567314 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP perfluoroundecanoic acid results in decreased expression of GCLC mRNA CTD PMID:23567314 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gdf15 growth differentiation factor 15 decreases expression ISO perfluoroundecanoic acid results in decreased expression of GDF15 protein CTD PMID:32916415 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO perfluoroundecanoic acid results in increased expression of GNRHR mRNA CTD PMID:33549592 NCBI chr 5:86,328,613...86,345,760
Ensembl chr 5:86,328,613...86,345,760 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO perfluoroundecanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO perfluoroundecanoic acid results in increased expression of GSTM3 mRNA CTD PMID:35337807 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression
affects expression		 ISO perfluoroundecanoic acid results in decreased expression of HADHA mRNA
perfluoroundecanoic acid affects the expression of HADHA mRNA		 CTD PMID:22071372 PMID:23567314 NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO perfluoroundecanoic acid results in increased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO perfluoroundecanoic acid results in decreased expression of HBEGF protein CTD PMID:32916415 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO perfluoroundecanoic acid results in decreased expression of HGF protein CTD PMID:32916415 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Hhex hematopoietically expressed homeobox increases expression ISO perfluoroundecanoic acid results in increased expression of HHEX mRNA CTD PMID:22071372 NCBI chr19:37,423,289...37,429,179
Ensembl chr19:37,423,258...37,429,179 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 decreases expression
increases expression		 EXP
ISO		 perfluoroundecanoic acid results in decreased expression of HMGCS1 mRNA
perfluoroundecanoic acid results in increased expression of HMGCS1 mRNA		 CTD PMID:23567314 PMID:35337807 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO perfluoroundecanoic acid results in increased expression of HMOX1 mRNA CTD PMID:23567314 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of HSD11B1 mRNA; perfluoroundecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:33549592 PMID:35143807 NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO perfluoroundecanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression ISO perfluoroundecanoic acid results in decreased expression of HSD17B3 mRNA; perfluoroundecanoic acid results in decreased expression of HSD17B3 protein CTD PMID:33549592 NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
decreases activity		 ISO perfluoroundecanoic acid results in decreased expression of HSD3B1 mRNA; perfluoroundecanoic acid results in decreased expression of HSD3B1 protein
perfluoroundecanoic acid results in decreased activity of HSD3B1 protein		 CTD PMID:33549592 PMID:35143807 PMID:36122607 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110 		JBrowse link
G Il16 interleukin 16 decreases expression ISO perfluoroundecanoic acid results in decreased expression of IL16 protein CTD PMID:32916415 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934 		JBrowse link
G Il18 interleukin 18 decreases expression ISO perfluoroundecanoic acid results in decreased expression of IL18 protein CTD PMID:32916415 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il6 interleukin 6 decreases expression ISO perfluoroundecanoic acid results in decreased expression of IL6 protein CTD PMID:32916415 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Insl3 insulin-like 3 decreases expression ISO perfluoroundecanoic acid results in decreased expression of INSL3 mRNA; perfluoroundecanoic acid results in decreased expression of INSL3 protein CTD PMID:33549592 PMID:35143807 NCBI chr 8:72,141,896...72,143,221
Ensembl chr 8:72,141,858...72,143,219 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO perfluoroundecanoic acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877 		JBrowse link
G Lhb luteinizing hormone beta decreases secretion
decreases expression		 ISO perfluoroundecanoic acid results in decreased secretion of LHB protein
perfluoroundecanoic acid results in decreased expression of LHB mRNA		 CTD PMID:33549592 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression ISO perfluoroundecanoic acid results in decreased expression of LHCGR mRNA; perfluoroundecanoic acid results in decreased expression of LHCGR protein CTD PMID:33549592 NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha decreases expression ISO perfluoroundecanoic acid results in decreased expression of MAP1LC3A protein CTD PMID:33549592 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO perfluoroundecanoic acid results in increased expression of MAP1LC3B protein CTD PMID:33549592 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation ISO perfluoroundecanoic acid results in decreased phosphorylation of MAPK1 protein CTD PMID:35143807 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation ISO perfluoroundecanoic acid results in decreased phosphorylation of MAPK3 protein CTD PMID:35143807 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO perfluoroundecanoic acid results in decreased phosphorylation of MTOR protein CTD PMID:33549592 PMID:35143807 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO perfluoroundecanoic acid results in increased expression of MTTP mRNA CTD PMID:35337807 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression EXP perfluoroundecanoic acid results in decreased expression of NFE2L2 mRNA CTD PMID:23567314 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO perfluoroundecanoic acid results in increased expression of NR1I2 mRNA CTD PMID:35337807 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of NR5A1 mRNA; perfluoroundecanoic acid results in decreased expression of NR5A1 protein CTD PMID:33549592 NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554 		JBrowse link
G Pax8 paired box 8 increases expression ISO perfluoroundecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO perfluoroundecanoic acid results in increased expression of PCK2 mRNA CTD PMID:35337807 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 increases expression EXP perfluoroundecanoic acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309 		JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluoroundecanoic acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO perfluoroundecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity
increases expression		 ISO
EXP		 perfluoroundecanoic acid results in increased activity of PPARA protein
perfluoroundecanoic acid results in increased expression of PPARA mRNA		 CTD PMID:22107727 PMID:35337807 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 ISO perfluoroundecanoic acid binds to and affects the folding of PPARG protein
perfluoroundecanoic acid results in increased expression of PPARG mRNA		 CTD PMID:24998974 PMID:35337807 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluoroundecanoic acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Retn resistin decreases expression ISO perfluoroundecanoic acid results in decreased expression of RETN protein CTD PMID:32916415 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of SCARB1 mRNA; perfluoroundecanoic acid results in decreased expression of SCARB1 protein CTD PMID:33549592 PMID:35143807 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO perfluoroundecanoic acid results in increased expression of SCD mRNA CTD PMID:35337807 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303 		JBrowse link
G Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A decreases expression EXP perfluoroundecanoic acid results in decreased expression of SERPINA1A mRNA CTD PMID:23567314 NCBI chr12:103,819,554...103,829,878
Ensembl chr12:103,819,848...103,829,821 		JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of SERPIND1 mRNA CTD PMID:23567314 NCBI chr16:17,149,235...17,161,438
Ensembl chr16:17,149,235...17,161,439 		JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO perfluoroundecanoic acid results in increased expression of SLC25A34 mRNA CTD PMID:23567314 NCBI chr 4:141,346,130...141,351,202
Ensembl chr 4:141,346,135...141,351,132 		JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 increases expression EXP perfluoroundecanoic acid results in increased expression of SLC27A1 mRNA CTD PMID:23567314 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946 		JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases expression
increases expression		 ISO perfluoroundecanoic acid results in decreased expression of SOD1 mRNA; perfluoroundecanoic acid results in decreased expression of SOD1 protein
perfluoroundecanoic acid results in increased expression of SOD1 mRNA		 CTD PMID:33549592 PMID:35337807 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression ISO perfluoroundecanoic acid results in decreased expression of SOD2 mRNA; perfluoroundecanoic acid results in decreased expression of SOD2 protein CTD PMID:33549592 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Spon1 spondin 1, (f-spondin) extracellular matrix protein decreases expression ISO perfluoroundecanoic acid results in decreased expression of SPON1 protein CTD PMID:32916415 NCBI chr 7:113,365,235...113,642,610
Ensembl chr 7:113,365,235...113,642,605 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of SQSTM1 protein CTD PMID:33549592 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO perfluoroundecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO perfluoroundecanoic acid results in decreased expression of STAR mRNA; perfluoroundecanoic acid results in decreased expression of STAR protein CTD PMID:33549592 PMID:35143807 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 increases expression ISO perfluoroundecanoic acid results in increased expression of SULT2A1 mRNA CTD PMID:35337807 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO perfluoroundecanoic acid binds to THRA protein CTD PMID:24819616 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b decreases expression ISO perfluoroundecanoic acid results in decreased expression of TNFRSF1B protein CTD PMID:32916415 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 decreases expression ISO perfluoroundecanoic acid results in decreased expression of TNFSF14 protein CTD PMID:32916415 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177 		JBrowse link
G Tshb thyroid stimulating hormone, beta subunit increases expression ISO perfluoroundecanoic acid results in increased expression of TSHB mRNA CTD PMID:33182161 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034 		JBrowse link
G Ttr transthyretin multiple interactions ISO perfluoroundecanoic acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Tusc3 tumor suppressor candidate 3 multiple interactions ISO [perfluoroundecanoic acid affects the methylation of TUSC3 gene] which affects the expression of TUSC3 mRNA CTD PMID:32653021 NCBI chr 8:39,472,505...39,620,091
Ensembl chr 8:39,472,999...39,619,367 		JBrowse link
G Txnip thioredoxin interacting protein affects expression ISO perfluoroundecanoic acid affects the expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO perfluoroundecanoic acid results in decreased expression of VEGFA protein CTD PMID:32916415 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      biological role 22178
        xenobiotic 19686
          perfluoroundecanoic acid 103
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    p-block element atom 22120
                      carbon group element atom 21920
                        carbon atom 21846
                          organic molecular entity 21846
                            heteroorganic entity 21500
                              organochalcogen compound 20983
                                organooxygen compound 20824
                                  carbon oxoacid 19606
                                    carboxylic acid 19602
                                      monocarboxylic acid 18969
                                        fatty acid 17131
                                          saturated fatty acid 16850
                                            straight-chain saturated fatty acid 16274
                                              undecanoic acid 104
                                                perfluoroundecanoic acid 103
paths to the root