CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: perfluoropentanoic acid
Accession: CHEBI:83491
browse the term
Definition: A monocarboxylic acid that is perfluorinated pentanoic acid.
Synonyms: exact_synonym: nonafluoropentanoic acid
related_synonym: 2,2,3,3,4,4,5,5,5-nonafluoropentanoic acid; Formula=C5HF9O2; InChI=1S/C5HF9O2/c6-2(7,1(15)16)3(8,9)4(10,11)5(12,13)14/h(H,15,16); InChIKey=CXZGQIAOTKWCDB-UHFFFAOYSA-N; SMILES=C(C(C(C(C(O)=O)(F)F)(F)F)(F)F)(F)(F)F; nonafluoro-1-pentanoic acid; perfluorovaleric acid
xref: CAS:2706-90-3
xref_mesh: MESH:C000619812
xref: PMID:24206563; PMID:24867700; PMID:24952613; Reaxys:1800087
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Acox1
acyl-CoA oxidase 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of ACOX1 mRNA
CTD
PMID:36435305
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of CYP7A1 mRNA
CTD
PMID:35337807
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Egr3
early growth response 3
multiple interactions
ISO
perfluoropentanoic acid inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA]
CTD
PMID:33111528
NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
increases expression
ISO
perfluoropentanoic acid results in increased expression of EHHADH mRNA
CTD
PMID:36435305
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Esr1
estrogen receptor 1
affects binding
ISO
perfluoropentanoic acid binds to [ESR1 protein binds to Estradiol]
CTD
PMID:33111528
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Fabp1
fatty acid binding protein 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of FABP1 mRNA
CTD
PMID:36435305
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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Flg
filaggrin
increases expression
ISO
perfluoropentanoic acid results in increased expression of FLG mRNA
CTD
PMID:36435305
NCBI chr 2:178,884,793...178,912,986
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Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
increases expression
ISO
perfluoropentanoic acid results in increased expression of GPAM mRNA
CTD
PMID:35337807
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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Gsta1
glutathione S-transferase alpha 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of GSTA1 mRNA
CTD
PMID:35337807
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of HMGCS1 mRNA
CTD
PMID:35337807
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Il6
interleukin 6
increases expression
ISO
perfluoropentanoic acid results in increased expression of IL6 mRNA
CTD
PMID:36435305
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Krt10
keratin 10
increases expression
ISO
perfluoropentanoic acid results in increased expression of KRT10 mRNA
CTD
PMID:36435305
NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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Loricrin
loricrin cornified envelope precursor protein
increases expression
ISO
perfluoropentanoic acid results in increased expression of LORICRIN mRNA
CTD
PMID:36435305
NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of NQO1 mRNA
CTD
PMID:35337807
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases expression
ISO
perfluoropentanoic acid results in increased expression of NR1I2 mRNA
CTD
PMID:35337807
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
increases expression
ISO
perfluoropentanoic acid results in increased expression of PCK2 mRNA
CTD
PMID:35337807
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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Pltp
phospholipid transfer protein
increases expression
ISO
perfluoropentanoic acid results in increased expression of PLTP mRNA
CTD
PMID:36435305
NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
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Ppara
peroxisome proliferator activated receptor alpha
increases activity increases expression decreases expression
ISO
perfluoropentanoic acid results in increased activity of PPARA protein perfluoropentanoic acid results in increased expression of PPARA mRNA perfluoropentanoic acid results in decreased expression of PPARA mRNA
CTD
PMID:28857218 PMID:35337807 PMID:36435305
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Ppard
peroxisome proliferator-activated receptor delta
decreases expression
ISO
perfluoropentanoic acid results in decreased expression of PPARD mRNA
CTD
PMID:36435305
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
increases expression
ISO
perfluoropentanoic acid results in increased expression of PPARG mRNA
CTD
PMID:36435305
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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S100a7a
S100 calcium binding protein A7A
increases expression
ISO
perfluoropentanoic acid results in increased expression of S100A7A mRNA
CTD
PMID:36435305
NCBI chr 2:176,151,405...176,155,846
Ensembl chr 2:176,151,288...176,156,441
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Serpine1
serpin family E member 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of SERPINE1 mRNA
CTD
PMID:36435305
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Sod1
superoxide dismutase 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of SOD1 mRNA
CTD
PMID:35337807
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Srebf1
sterol regulatory element binding transcription factor 1
increases expression
ISO
perfluoropentanoic acid results in increased expression of SREBF1 mRNA
CTD
PMID:35337807
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Tff1
trefoil factor 1
multiple interactions
ISO
perfluoropentanoic acid inhibits the reaction [Estradiol results in increased expression of TFF1 mRNA]
CTD
PMID:33111528
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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Tslp
thymic stromal lymphopoietin
increases expression
ISO
perfluoropentanoic acid results in increased expression of TSLP mRNA
CTD
PMID:36435305
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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