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Accession:CHEBI:83168 term browser browse the term
Definition:A member of the class of pyridines that is (pyridin-2-yl)acrylic acid substituted at position 6 by a [(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl group. It is a non-sedating antihistamine used for treatment of hayfever, urticaria, and rhinitis.
Synonyms:exact_synonym: (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid
 related_synonym: (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid;   BW 825C;   BW A825C;   Formula=C22H24N2O2;   InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H,2-3,14-16H2,1H3,(H,25,26)/b12-11+,20-13+;   InChIKey=PWACSDKDOHSSQD-IUTFFREVSA-N;   SMILES=Cc1ccc(cc1)C(=C/CN1CCCC1)\\c1cccc(\\C=C\\C(O)=O)n1;   acrivastina;   acrivastinum
 xref: CAS:87848-99-5 "ChemIDplus";   CAS:87848-99-5 "KEGG DRUG";   Drug_Central:82 "DrugCentral";   KEGG:D02760
 xref_mesh: MESH:C043648
 xref: PMID:1355745 "Europe PMC";   PMID:1715267 "Europe PMC";   PMID:18968530 "Europe PMC";   PMID:1970907 "Europe PMC";   PMID:22936420 "Europe PMC";   PMID:23047471 "Europe PMC";   PMID:24813276 "Europe PMC";   PMID:2569998 "Europe PMC";   PMID:2569999 "Europe PMC";   PMID:2570000 "Europe PMC";   PMID:2570001 "Europe PMC";   PMID:2570003 "Europe PMC";   PMID:2574054 "Europe PMC";   PMID:2859204 "Europe PMC";   PMID:2901993 "Europe PMC";   PMID:2906886 "Europe PMC";   PMID:6149965 "Europe PMC";   PMID:7860231 "Europe PMC";   PMID:8630717 "Europe PMC";   Reaxys:6739893 "Reaxys";   Wikipedia:Acrivastine

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acrivastine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          antagonist 15784
            histamine antagonist 4485
              H1-receptor antagonist 4009
                acrivastine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          N-alkylpyrrolidine 1092
                                            acrivastine 1
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