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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluxapyroxad
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Accession:CHEBI:83113 term browser browse the term
Definition:An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families.
Synonyms:related_synonym: 3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide;   Formula=C18H12F5N3O;   InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27);   InChIKey=SXSGXWCSHSVPGB-UHFFFAOYSA-N;   SMILES=Cn1cc(C(=O)Nc2ccccc2-c2cc(F)c(F)c(F)c2)c(n1)C(F)F
 xref: CAS:907204-31-3
 xref_mesh: MESH:C000591719
 xref: PMID:22999200;   PMID:25039069;   PMID:25146353;   PMID:25151827;   PPDB:2002;   Patent:DE102011017670;   Patent:NZ587123;   Pesticides:fluxapyroxad;   Reaxys:15702063


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fluxapyroxad term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa10 annexin A10 increases expression ISO fluxapyroxad results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Arg1 arginase 1 decreases expression ISO fluxapyroxad results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP1A1 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP1A1 protein CTD PMID:29294346 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions
ISO fluxapyroxad results in increased expression of CYP2B6 mRNA; fluxapyroxad results in increased expression of CYP2B6 protein
[fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP2B6 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP2B6 protein
CTD PMID:29294346 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO fluxapyroxad results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO fluxapyroxad results in decreased expression of CYP7A1 mRNA; fluxapyroxad results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO fluxapyroxad results in decreased expression of G6PC mRNA CTD PMID:32194361 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pesticide 16432
          antifungal agrochemical 7721
            fluxapyroxad 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  heteroarene 16469
                                    monocyclic heteroarene 13315
                                      azole 12482
                                        diazole 8135
                                          pyrazoles 1299
                                            fluxapyroxad 7
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