CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Polygodial
Accession: CHEBI:8305
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Definition: An aldehyde that has formula C15H22O2.
Synonyms: related_synonym: Formula=C15H22O2; InChI=1S/C15H22O2/c1-14(2)7-4-8-15(3)12(10-17)11(9-16)5-6-13(14)15/h5,9-10,12-13H,4,6-8H2,1-3H3/t12-,13-,15+/m0/s1; InChIKey=AZJUJOFIHHNCSV-KCQAQPDRSA-N; SMILES=CC1(C)CCC[C@@]2(C)[C@H]1CC=C(C=O)[C@@H]2C=O
xref: CAS:6754-20-7; KEGG:C09712; KNApSAcK:C00003175
xref_mesh: MESH:C034380
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Akt1
AKT serine/threonine kinase 1
decreases phosphorylation
EXP
polygodial results in decreased phosphorylation of AKT1 protein
CTD
PMID:27645309
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
polygodial results in increased expression of BAX protein
CTD
PMID:30935903
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
polygodial results in decreased expression of BCL2 protein
CTD
PMID:30935903
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Casp3
caspase 3
increases activity
ISO
polygodial results in increased activity of CASP3 protein
CTD
PMID:30935903
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
increases cleavage
ISO
polygodial results in increased cleavage of CASP9 protein
CTD
PMID:30935903
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Dusp1
dual specificity phosphatase 1
increases expression
EXP
polygodial results in increased expression of DUSP1 protein
CTD
PMID:27645309
NCBI chr10:16,680,478...16,683,275
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Htr3a
5-hydroxytryptamine receptor 3A
decreases activity
ISO
polygodial results in decreased activity of HTR3A protein
CTD
PMID:26456648
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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Mapk1
mitogen activated protein kinase 1
decreases phosphorylation
EXP
polygodial results in decreased phosphorylation of MAPK1 protein
CTD
PMID:27645309
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
decreases phosphorylation
EXP
polygodial results in decreased phosphorylation of MAPK3 protein
CTD
PMID:27645309
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects localization
EXP
polygodial affects the localization of NR3C1 protein
CTD
PMID:27645309
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Rasd1
ras related dexamethasone induced 1
increases expression
EXP
polygodial results in increased expression of RASD1 protein
CTD
PMID:27645309
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
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