The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
24-hydroxycholesterol promotes the reaction [APOA1 protein results in increased transport of Cholesterol] 24-hydroxycholesterol results in increased secretion of APOA1 protein
7-ketocholesterol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein]
APOA1 protein results in increased transport of Cholesterol 24-hydroxycholesterol promotes the reaction [APOA1 protein results in increased transport of Cholesterol]; Fenofibrate inhibits the reaction [APOA1 protein results in increased transport of Cholesterol]; Fenofibrate promotes the reaction [APOA1 protein results in increased transport of Cholesterol]; Pioglitazone promotes the reaction [APOA1 protein results in increased transport of Cholesterol]; T0901317 promotes the reaction [APOA1 protein results in increased transport of Cholesterol]; Troglitazone promotes the reaction [APOA1 protein results in increased transport of Cholesterol]
Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]]
Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]; Zinc Acetate inhibits the reaction [Linoleic Acid results in increased activity of CASP3 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]; Zinc Acetate promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]]
Linoleic Acid results in increased expression of IL6 mRNA; Linoleic Acid results in increased expression of IL6 protein 2,4-thiazolidinedione inhibits the reaction [Linoleic Acid results in increased expression of IL6 protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of IL6 mRNA]
PPARG protein promotes the reaction [Linoleic Acid results in increased activity of RELA protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein]; Vitamin E inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein]
Linoleic Acid results in increased expression of PTGS2 mRNA Linoleic Acid promotes the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 mRNA]; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 protein]; Polychlorinated Biphenyls promotes the reaction [[Linoleic Acid results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; prolinedithiocarbamate inhibits the reaction [[Linoleic Acid co-treated with Polychlorinated Biphenyls] results in increased expression of PTGS2 mRNA]; prolinedithiocarbamate inhibits the reaction [Linoleic Acid results in increased expression of PTGS2 mRNA]
2,4-thiazolidinedione inhibits the reaction [Linoleic Acid results in increased activity of RELA protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased activity of RELA protein]
Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]; Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]]; Zinc Acetate promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]]
Linoleic Acid results in increased expression of VCAM1 mRNA [Linoleic Acid co-treated with Polychlorinated Biphenyls] results in increased expression of VCAM1 protein; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA]; prolinedithiocarbamate inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA]