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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:naloxegol
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Accession:CHEBI:82975 term browser browse the term
Definition:An organic heteropentacyclic compound that is naloxone in which the keto group is replaced by a PEG moiety. Used for treatment of opioid-induced constipation.
Synonyms:related_synonym: Formula=C34H53NO11;   InChI=1S/C34H53NO11/c1-3-9-35-10-8-33-30-26-4-5-27(36)31(30)46-32(33)28(6-7-34(33,37)29(35)25-26)45-24-23-44-22-21-43-20-19-42-18-17-41-16-15-40-14-13-39-12-11-38-2/h3-5,28-29,32,36-37H,1,6-25H2,2H3/t28-,29+,32-,33-,34+/m0/s1;   InChIKey=XNKCCCKFOQNXKV-ZRSCBOBOSA-N;   NKTR-118;   NKTR118;   SMILES=COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45
 xref: CAS:854601-70-0;   Drug_Central:4832;   KEGG:D10479;   PMID:23726675;   PMID:24238792;   PMID:24896818;   PMID:24945932;   PMID:24946021;   PMID:25112584;   PMID:25209526;   PMID:25220391;   PMID:25278772;   Reaxys:14435712;   Wikipedia:Naloxegol


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        biophysical role 14056
          cathartic 42
            naloxegol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organonitrogen compound 18783
                                alkaloid 7817
                                  isoquinoline alkaloid 1191
                                    morphinane alkaloid 696
                                      morphinan 663
                                        naloxone 81
                                          naloxegol 0
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