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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aliphatic aldoxime
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Accession:CHEBI:82744 term browser browse the term
Definition:Any aldoxime derived from an aliphatic aldehyde.
Synonyms:related_synonym: Formula=CH2NOR;   SMILES=ON=C[*];   an aliphatic aldoxime
 xref: MetaCyc:Aliphatic-Aldoximes


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acetaldehyde oxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO acetaldehyde oxime inhibits the reaction [tabun results in decreased activity of ACHE protein] CTD PMID:22960624 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
aldicarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP
ISO
Aldicarb results in decreased activity of ACHE protein CTD PMID:8134223, PMID:14644616, PMID:16256972, PMID:21251949, PMID:23962483, PMID:27132127 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Aldicarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP Aldicarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Aldicarb inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Aldicarb results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Nefh neurofilament heavy increases phosphorylation ISO Aldicarb results in increased phosphorylation of NEFH protein CTD PMID:16256972 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nrxn1 neurexin 1 multiple interactions ISO NRXN1 protein affects the reaction [NLG-1 results in increased susceptibility to Aldicarb]; NRXN1 protein affects the reaction [NRX-1 results in decreased susceptibility to Aldicarb] CTD PMID:23638761 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Aldicarb inhibits the reaction [Progesterone results in increased activity of PGR protein] CTD PMID:9126867 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO
EXP
[Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb CTD PMID:27132127 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Vpreb1 V-set pre-B cell surrogate light chain 1 decreases expression ISO Aldicarb results in decreased expression of VPREB1 mRNA CTD PMID:25424538 NCBI chr11:88,376,256...88,377,133
Ensembl chr11:88,376,256...88,377,133
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          nitrogen atom 18565
            nitrogen molecular entity 18565
              oxime 176
                aldoxime 82
                  aliphatic aldoxime 10
                    (1E)-2,3,4,5,6-pentahydroxyhexanal oxime 0
                    (methylsulfanyl)acetaldehyde oxime 0
                    2-methyl-2-(methylsulfanyl)propanal oxime + 10
                    2-methylbutanal oxime + 0
                    2-methylpropanal oxime + 0
                    3-(methylsulfanyl)propanal oxime 0
                    3-Methylbutyraldehyde oxime 0
                    4-(methylsulfanyl)butanal oxime 0
                    5-(methylsulfanyl)pentanal oxime + 0
                    6-(methylsulfanyl)hexanal oxime + 0
                    7-(methylsulfanyl)heptanal oxime + 0
                    8-(methylsulfanyl)octanal oxime + 0
                    9-(methylsulfanyl)nonanal oxime + 0
                    IC202C 0
                    acetaldehyde oxime + 1
                    butanal oxime 0
                    omega-(methylsulfanyl)-(E)-alkanal oxime + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      p-block molecular entity 19702
                        pnictogen molecular entity 18674
                          nitrogen molecular entity 18565
                            oxime 176
                              aldoxime 82
                                aliphatic aldoxime 10
                                  (1E)-2,3,4,5,6-pentahydroxyhexanal oxime 0
                                  (methylsulfanyl)acetaldehyde oxime 0
                                  2-methyl-2-(methylsulfanyl)propanal oxime + 10
                                  2-methylbutanal oxime + 0
                                  2-methylpropanal oxime + 0
                                  3-(methylsulfanyl)propanal oxime 0
                                  3-Methylbutyraldehyde oxime 0
                                  4-(methylsulfanyl)butanal oxime 0
                                  5-(methylsulfanyl)pentanal oxime + 0
                                  6-(methylsulfanyl)hexanal oxime + 0
                                  7-(methylsulfanyl)heptanal oxime + 0
                                  8-(methylsulfanyl)octanal oxime + 0
                                  9-(methylsulfanyl)nonanal oxime + 0
                                  IC202C 0
                                  acetaldehyde oxime + 1
                                  butanal oxime 0
                                  omega-(methylsulfanyl)-(E)-alkanal oxime + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.