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Accession:CHEBI:82700 term browser browse the term
Definition:A member of the class of benzoxazine that is 6-hydroxy-1,4-benzoxazin-3-one in which the hydrogen at position 4 is replaced by a (1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl group. Used (as its hydrochloride salt) for long-term treatment of airflow obstruction in patients with chronic obstructive pulmonary disease including chronic bronchitis and/or emphysema.
Synonyms:exact_synonym: 6-hydroxy-8-[(1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl]-2H-1,4-benzoxazin-3(4H)-one
 related_synonym: BI 1744;   Formula=C21H26N2O5;   InChI=1S/C21H26N2O5/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26)/t18-/m0/s1;   InChIKey=COUYJEVMBVSIHV-SFHVURJKSA-N;   SMILES=COc1ccc(CC(C)(C)NC[C@H](O)c2cc(O)cc3NC(=O)COc23)cc1
 xref: CAS:868049-49-4 "ChemIDplus";   Drug_Central:4814 "DrugCentral";   KEGG:D10145
 xref_mesh: MESH:C549647
 xref: PMID:20096576 "Europe PMC";   PMID:20371707 "Europe PMC";   PMID:21839850 "Europe PMC";   PMID:24158691 "Europe PMC";   PMID:24247039 "Europe PMC";   PMID:24269928 "Europe PMC";   PMID:24307202 "Europe PMC";   PMID:24966672 "Europe PMC";   PMID:25045258 "Europe PMC";   PMID:25114521 "Europe PMC";   PMID:25187881 "Europe PMC";   Reaxys:12431799 "Reaxys";   Wikipedia:Olodaterol
 cyclic_relationship: is_conjugate_base_of CHEBI:83312

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olodaterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            bronchodilator agent 1827
              olodaterol 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        secondary amino compound 6358
                                          olodaterol 3
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