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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pirimicarb
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Accession:CHEBI:8248 term browser browse the term
Definition:An aminopyrimidine that is N,N,4,5-tetramethylpyrimidin-2-amine substituted by a (dimethylcarbamoyl)oxy group at position 4.
Synonyms:exact_synonym: 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate
 related_synonym: Dimethylcarbamic acid 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester;   Formula=C11H18N4O2;   InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3;   InChIKey=YFGYUFNIOHWBOB-UHFFFAOYSA-N;   SMILES=CN(C)C(=O)Oc1nc(nc(C)c1C)N(C)C
 xref: Beilstein:663442;   CAS:23103-98-2;   KEGG:C11079
 xref_mesh: MESH:C011994
 xref: PMID:17220085;   PMID:23598106;   PMID:23616278;   PMID:23992615;   PPDB:530;   Pesticides:pirimicarb;   Reaxys:663442;   Wikipedia:Pirimicarb


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pirimicarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO pirimicarb results in decreased activity of ACHE protein CTD PMID:33037899 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO pirimicarb results in increased activity of CYP19A1 protein CTD PMID:11884232 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression ISO pirimicarb results in decreased expression of ESR1 mRNA CTD PMID:15261991 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Hspa1a heat shock protein 1A decreases expression ISO pirimicarb results in decreased expression of HSPA1A protein CTD PMID:16271832 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa5 heat shock protein 5 increases expression ISO pirimicarb results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa8 heat shock protein 8 decreases expression ISO pirimicarb results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hspb2 heat shock protein 2 decreases expression ISO pirimicarb results in decreased expression of HSPB2 protein CTD PMID:16271832 NCBI chr 9:50,662,372...50,663,654
Ensembl chr 9:50,662,378...50,663,654 		JBrowse link
G Lep leptin multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of LEP protein CTD PMID:29321614 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lepr leptin receptor multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Nmb neuromedin B multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of NMB mRNA CTD PMID:29321614 NCBI chr 7:80,551,975...80,554,810
Ensembl chr 7:80,551,975...80,554,824 		JBrowse link
G Nmbr neuromedin B receptor multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NMBR mRNA CTD PMID:29321614 NCBI chr10:14,634,894...14,647,202
Ensembl chr10:14,581,335...14,646,594 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NPY1R mRNA CTD PMID:29321614 NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444 		JBrowse link
G Trp53 transformation related protein 53 affects activity ISO pirimicarb metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
Term paths to the root
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  CHEBI ontology 22178
    role 22194
      application 21744
        agrochemical 16939
          pirimicarb 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  azane 18426
                                    ammonia 18425
                                      organic amino compound 18425
                                        amino acid 16428
                                          dimethylcarbamic acid 13
                                            pirimicarb 13
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