CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Doxylamine succinate
Accession: CHEBI:82461
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Definition: An organic molecular entity that has formula C21H28N2O5.
Synonyms: related_synonym: Formula=C21H28N2O5; InChI=1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8); InChIKey=KBAUFVUYFNWQFM-UHFFFAOYSA-N; SMILES=OC(=O)CCC(O)=O.CN(C)CCOC(C)(c1ccccc1)c1ccccn1
xref: CAS:562-10-7; KEGG:C19414; KEGG:D02327
xref_mesh: MESH:C035385
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Aldh1a2
aldehyde dehydrogenase 1 family, member A2
decreases expression
ISO
doxylamine succinate results in decreased expression of ALDH1A2 mRNA
CTD
PMID:31711903
NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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Foxc2
forkhead box C2
decreases expression
ISO
doxylamine succinate results in decreased expression of FOXC2 mRNA
CTD
PMID:31711903
NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
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Il24
interleukin 24
decreases expression
ISO
doxylamine succinate results in decreased expression of IL24 mRNA
CTD
PMID:32816093
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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Meox1
mesenchyme homeobox 1
decreases expression
ISO
doxylamine succinate results in decreased expression of MEOX1 mRNA
CTD
PMID:31711903
NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
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Mesp2
mesoderm posterior bHLH transcription factor 2
decreases expression
ISO
doxylamine succinate results in decreased expression of MESP2 mRNA
CTD
PMID:31711903
NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198
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Neurog2
neurogenin 2
increases expression
ISO
doxylamine succinate results in increased expression of NEUROG2 mRNA
CTD
PMID:31711903
NCBI chr 2:216,092,709...216,095,276
Ensembl chr 2:216,093,363...216,094,154
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