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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Dibromoacetonitrile
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Accession:CHEBI:82445 term browser browse the term
Definition:An aliphatic nitrile that has formula C2HBr2N.
Synonyms:related_synonym: Formula=C2HBr2N;   InChI=1S/C2HBr2N/c3-2(4)1-5/h2H;   InChIKey=NDSBDLSWTGLNQA-UHFFFAOYSA-N;   SMILES=BrC(Br)C#N
 xref: CAS:3252-43-5;   KEGG:C19396
 xref_mesh: MESH:C051715



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Dibromoacetonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO dibromoacetonitrile results in increased expression of GCLC mRNA CTD PMID:35842135 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO dibromoacetonitrile results in increased expression of HGF mRNA CTD PMID:21986297 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO dibromoacetonitrile results in increased expression of HMOX1 mRNA CTD PMID:35842135 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Met met proto-oncogene increases expression ISO dibromoacetonitrile results in increased expression of MET mRNA CTD PMID:21986297 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases oxidation
ISO 4-aminobenzhydrazide inhibits the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; [MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides; Acetylcysteine promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Acetylcysteine promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Cysteine promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Cysteine promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Glutathione promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Glutathione promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Hydrogen Peroxide promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Hydrogen Peroxide promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Indomethacin inhibits the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Indomethacin inhibits the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Penicillamine promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Penicillamine promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Potassium Chloride promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Potassium Chloride promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Sodium Azide inhibits the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Azide inhibits the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; Sodium Hypochlorite promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Hypochlorite promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile] CTD PMID:25614581 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Myc myelocytomatosis oncogene increases expression ISO dibromoacetonitrile results in increased expression of MYC mRNA CTD PMID:21986297 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects response to substance
increases expression
ISO NFE2L2 protein affects the susceptibility to dibromoacetonitrile
dibromoacetonitrile results in increased expression of NFE2L2 mRNA; dibromoacetonitrile results in increased expression of NFE2L2 protein
CTD PMID:35842135 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO dibromoacetonitrile results in increased expression of NQO1 mRNA CTD PMID:35842135 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression ISO dibromoacetonitrile results in increased expression of SRXN1 mRNA CTD PMID:35842135 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    chemical entity 22193
      group 22088
        pseudohalo group 4677
          cyano group 4677
            nitrile 4677
              aliphatic nitrile 2287
                Dibromoacetonitrile 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    p-block element atom 22120
                      carbon group element atom 21920
                        carbon atom 21846
                          organic molecular entity 21846
                            one-carbon compound 18590
                              hydrogen cyanide 4894
                                cyanides 4877
                                  nitrile 4677
                                    aliphatic nitrile 2287
                                      Dibromoacetonitrile 9
paths to the root