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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Benzoyl peroxide
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Accession:CHEBI:82405 term browser browse the term
Definition:A carbonyl compound that has formula C14H10O4.
Synonyms:related_synonym: Formula=C14H10O4;   InChI=1S/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H;   InChIKey=OMPJBNCRMGITSC-UHFFFAOYSA-N;   SMILES=O=C(OOC(=O)c1ccccc1)c1ccccc1;   acetoxyl;   benoxyl;   benzoperoxide;   benzoyl superoxide;   diphenylglyoxal peroxide
 xref: CAS:94-36-0;   Drug_Central:328;   HMDB:HMDB0032040;   KEGG:C19346;   KEGG:D03093
 xref_mesh: MESH:D001585
 xref: VSDB:1847



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Benzoyl peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity
multiple interactions
decreases activity
affects activity
ISO Benzoyl Peroxide results in increased activity of CAT protein
[Benzoyl Peroxide co-treated with Erythromycin] results in decreased activity of CAT protein; CAT protein inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]
Benzoyl Peroxide results in decreased activity of CAT protein
Benzoyl Peroxide affects the activity of CAT protein
2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; cycloartenol inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Iron deficiency inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Iron promotes the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]
CTD PMID:2126186 PMID:8979499 PMID:9142553 PMID:10753220 PMID:11809596 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cryz crystallin zeta affects activity
decreases activity
multiple interactions
ISO Benzoyl Peroxide affects the activity of CRYZ protein
Benzoyl Peroxide results in decreased activity of CRYZ protein
2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein]; cycloartenol inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein]; lupeol inhibits the reaction [Benzoyl Peroxide affects the activity of CRYZ protein]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein]
CTD PMID:12804013 PMID:15225900 PMID:15248479 PMID:15454305 PMID:15629248 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Egr1 early growth response 1 increases expression ISO Benzoyl Peroxide results in increased expression of EGR1 mRNA CTD PMID:15920718 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP Benzoyl Peroxide binds to and results in decreased activity of ESR1 protein CTD PMID:15348454 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression
increases expression
ISO Benzoyl Peroxide affects the expression of FOS
Benzoyl Peroxide results in increased expression of FOS
CTD PMID:8979499 PMID:9142553 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity
multiple interactions
ISO Benzoyl Peroxide results in decreased activity of G6PD protein
2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]; cycloartenol inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]
CTD PMID:12804013 PMID:15225900 PMID:15454305 PMID:15629248 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased expression of GJA1 mRNA
Benzoyl Peroxide results in increased expression of GJA1 mRNA
CTD PMID:7586191 PMID:8597533 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gjb2 gap junction protein, beta 2 multiple interactions
increases expression
ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] affects the expression of GJB2 protein
Benzoyl Peroxide results in increased expression of GJB2 mRNA
CTD PMID:7586191 PMID:8597533 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression ISO Benzoyl Peroxide results in decreased expression of GJB5 mRNA CTD PMID:8597533 NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO 2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; cycloartenol inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; Iron deficiency inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; Iron promotes the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein] CTD PMID:12067571 PMID:12504893 PMID:12804013 PMID:15225900 PMID:15454305 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases mutagenesis
ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased mutagenesis of HRAS gene
Benzoyl Peroxide results in increased mutagenesis of HRAS gene
CTD PMID:3115617 PMID:11241758 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] CTD PMID:10365914 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Benzoyl Peroxide results in increased expression of IL1A mRNA
Plant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A mRNA]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A protein]; Silymarin inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A protein]
Benzoyl Peroxide results in increased expression of IL1A mRNA; Benzoyl Peroxide results in increased expression of IL1A protein
CTD PMID:7665919 PMID:8435107 PMID:10753220 PMID:11522381 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il6 interleukin 6 increases expression ISO Benzoyl Peroxide results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression
increases expression
ISO Benzoyl Peroxide affects the expression of JUN
Benzoyl Peroxide results in increased expression of JUN
CTD PMID:8979499 PMID:9142553 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Benzoyl Peroxide results in increased expression of JUNB mRNA CTD PMID:15920718 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Mpo myeloperoxidase increases activity
multiple interactions
ISO Benzoyl Peroxide results in increased activity of MPO protein
Silymarin inhibits the reaction [Benzoyl Peroxide results in increased activity of MPO protein]
CTD PMID:10753220 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Benzoyl Peroxide results in decreased expression of NR3C1 mRNA; Benzoyl Peroxide results in decreased expression of NR3C1 protein CTD PMID:21533367 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases expression
increases activity
ISO 2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; allyl sulfide inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; cycloartenol inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron deficiency inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron promotes the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Masoprocol inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]
Benzoyl Peroxide results in increased expression of ODC1 mRNA
CTD PMID:1923905 PMID:2013121 PMID:2105358 PMID:2591024 PMID:12065085 More... NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity
multiple interactions
ISO Benzoyl Peroxide results in increased activity of PARP1 protein
3-aminobenzamide inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]; Butylated Hydroxytoluene inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]
CTD PMID:2120135 PMID:2126186 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO [2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate co-treated with Bisphenol A-Glycidyl Methacrylate co-treated with Benzoyl Peroxide] results in increased expression of PTGS2 mRNA; [2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate co-treated with Bisphenol A-Glycidyl Methacrylate co-treated with Benzoyl Peroxide] results in increased expression of PTGS2 protein
Benzoyl Peroxide results in increased expression of PTGS2 mRNA
CTD PMID:8989914 PMID:15264312 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sod1 superoxide dismutase 1 increases activity
affects activity
ISO Benzoyl Peroxide results in increased activity of SOD1 protein
Benzoyl Peroxide affects the activity of SOD1 protein
CTD PMID:8979499 PMID:9142553 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Benzoyl Peroxide results in increased expression of TGFB1 mRNA CTD PMID:8148055 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Xdh xanthine dehydrogenase affects activity
multiple interactions
increases activity
ISO Benzoyl Peroxide affects the activity of XDH protein
cycloartenol inhibits the reaction [Benzoyl Peroxide results in increased activity of XDH protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of XDH protein]; lupeol inhibits the reaction [Benzoyl Peroxide affects the activity of XDH protein]
CTD PMID:3677084 PMID:12804013 PMID:15225900 PMID:15248479 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link

Term paths to the root
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  CHEBI ontology 19812
    chemical entity 19812
      group 19734
        inorganic group 19260
          oxo group 18670
            organic oxo compound 18670
              carbonyl compound 18670
                Benzoyl peroxide 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      carbon group element atom 19631
                        carbon atom 19621
                          organic molecular entity 19621
                            organic group 18730
                              organic divalent group 18721
                                organodiyl group 18721
                                  carbonyl group 18670
                                    carbonyl compound 18670
                                      Benzoyl peroxide 24
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