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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-Nitrosodi-n-propylamine
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Accession:CHEBI:82358 term browser browse the term
Definition:A nitroso compound that has formula C6H14N2O.
Synonyms:related_synonym: Formula=C6H14N2O;   InChI=1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3;   InChIKey=YLKFDHTUAUWZPQ-UHFFFAOYSA-N;   SMILES=CCCN(CCC)N=O
 xref: CAS:621-64-7;   KEGG:C19279
 xref_mesh: MESH:C013161


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N-Nitrosodi-n-propylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5a cytochrome b5 type A multiple interactions ISO CYB5A protein promotes the reaction [CYP2A6 protein results in increased activity of N-nitroso(di-n-propyl)amine]; CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine] CTD PMID:15728263 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyb5b cytochrome b5 type B multiple interactions ISO [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine CTD PMID:11733072 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects metabolic processing
decreases nitrosation
increases hydroxylation		 EXP CYP2B1 protein affects the metabolism of N-nitroso(di-n-propyl)amine
CYP2B1 protein results in decreased nitrosation of N-nitroso(di-n-propyl)amine
CYP2B1 protein results in increased hydroxylation of N-nitroso(di-n-propyl)amine		 CTD PMID:8625499 PMID:10910959 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing ISO CYP2B6 protein affects the metabolism of N-nitroso(di-n-propyl)amine CTD PMID:10910959 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
affects metabolic processing
increases activity		 ISO [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine; CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine]
CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine		 CTD PMID:10910959 PMID:11035158 PMID:11733072 PMID:15728263 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases nitrosation
affects metabolic processing		 ISO CYP3A4 protein results in decreased nitrosation of N-nitroso(di-n-propyl)amine
CYP3A4 protein affects the metabolism of N-nitroso(di-n-propyl)amine		 CTD PMID:10910959 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine CTD PMID:11035158 PMID:11733072 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      group 19768
        inorganic group 19361
          nitroso group 5052
            nitroso compound 5062
              N-Nitrosodi-n-propylamine 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      p-block molecular entity 19759
                        pnictogen molecular entity 19022
                          nitrogen molecular entity 18934
                            nitroso compound 5062
                              N-Nitrosodi-n-propylamine 7
paths to the root