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ONTOLOGY REPORT - ANNOTATIONS


Term:piperacillin
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Accession:CHEBI:8232 term browser browse the term
Definition:A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group.
Synonyms:exact_synonym: 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   Formula=C23H27N5O7S;   InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1;   InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N;   Piperacillin anhydrous;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)c1ccccc1)C(O)=O
 alt_id: CHEBI:472443;   CHEBI:475140;   CHEBI:505944
 xref: Beilstein:6081140;   CAS:61477-96-1;   DrugBank:DB00319;   Drug_Central:2187;   KEGG:C14034;   KEGG:D08380;   LINCS:LSM-5924
 xref_mesh: MESH:D010878
 xref: PMID:1701026;   PMID:17116662;   PMID:17158942;   PMID:17851079;   PMID:25998949;   PMID:29017833;   PMID:29148816;   PMID:7486906;   Patent:DE2519400;   Patent:US4087424;   Reaxys:6081140;   Wikipedia:Piperacillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:52433


show annotations for term's descendants       view all columns           Sort by:
 
piperacillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:6480464
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:6480464
G Mir18a microRNA 18a JBrowse link 15 100,180,015 100,180,110 RGD:6480464
G Mir21 microRNA 21 JBrowse link 10 73,902,210 73,902,301 RGD:6480464
G Mr1 major histocompatibility complex, class I-related JBrowse link 13 72,771,992 72,789,861 RGD:6480464
G RT1-DMb RT1 class II, locus DMb JBrowse link 20 3,945,383 3,952,838 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        aetiopathogenetic role 18840
          allergen 16934
            penicillin 261
              piperacillin 12
                piperacilloyl group + 0
                piperacilloyl-L-lysine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18475
                              organic divalent group 18468
                                organodiyl group 18468
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic acid 18034
                                        carboacyl group 17190
                                          univalent carboacyl group 17190
                                            carbamoyl group 16928
                                              carboxamide 16928
                                                lactam 7829
                                                  beta-lactam 792
                                                    beta-lactam antibiotic 780
                                                      penams 261
                                                        penicillanic acids 261
                                                          penicillanic acid 261
                                                            6-aminopenicillanic acid 261
                                                              penicillin 261
                                                                penicillin allergen 258
                                                                  piperacillin 12
                                                                    piperacilloyl group + 0
                                                                    piperacilloyl-L-lysine + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.