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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3,3'-Dichlorobenzidine
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Accession:CHEBI:82315 term browser browse the term
Definition:A monochlorobenzene that has formula C12H10Cl2N2.
Synonyms:related_synonym: Formula=C12H10Cl2N2;   InChI=1S/C12H10Cl2N2/c13-9-5-7(1-3-11(9)15)8-2-4-12(16)10(14)6-8/h1-6H,15-16H2;   InChIKey=HUWXDEQWWKGHRV-UHFFFAOYSA-N;   SMILES=Nc1ccc(cc1Cl)-c1ccc(N)c(Cl)c1
 xref: CAS:91-94-1;   KEGG:C19225
 xref_mesh: MESH:D015101

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3,3'-Dichlorobenzidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP 3,3'-Dichlorobenzidine binds to and results in decreased activity of AHR protein CTD PMID:2555073 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Ar androgen receptor multiple interactions
affects localization		 ISO 3,3'-Dichlorobenzidine analog binds to and results in increased activity of AR protein; 3,3'-Dichlorobenzidine binds to and results in decreased activity of AR protein; 3,3'-Dichlorobenzidine inhibits the reaction [Metribolone results in increased activity of AR protein]
3,3'-Dichlorobenzidine analog affects the localization of AR protein		 CTD PMID:15950433, PMID:18324785, PMID:28478275 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression ISO 3,3'-Dichlorobenzidine affects the expression of BAX protein CTD PMID:24604609 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO 3,3'-Dichlorobenzidine affects the expression of BCL2 protein CTD PMID:24604609 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Casp3 caspase 3 increases activity ISO 3,3'-Dichlorobenzidine results in increased activity of CASP3 protein CTD PMID:24604609 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 increases activity ISO 3,3'-Dichlorobenzidine results in increased activity of CASP9 protein CTD PMID:24604609 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases metabolic processing
multiple interactions		 ISO
EXP		 CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine
lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine]		 CTD PMID:9310344 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 affects expression ISO 3,3'-Dichlorobenzidine affects the expression of HSPA4 protein CTD PMID:24604609 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397 		JBrowse link
G Por cytochrome p450 oxidoreductase affects metabolic processing EXP POR protein affects the metabolism of 3,3'-Dichlorobenzidine CTD PMID:3130202 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 affects expression ISO 3,3'-Dichlorobenzidine affects the expression of RUVBL2 protein CTD PMID:24604609 NCBI chr 1:101,413,766...101,426,970
Ensembl chr 1:101,413,766...101,426,852 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects expression ISO 3,3'-Dichlorobenzidine affects the expression of YWHAQ protein CTD PMID:24604609 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        polyatomic entity 19697
          molecule 19520
            cyclic compound 19324
              ring assembly 7010
                biphenyls 5766
                  3,3'-Dichlorobenzidine 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                carbocyclic compound 18183
                                  benzenoid aromatic compound 17180
                                    benzenes 16922
                                      chlorobenzenes 12992
                                        monochlorobenzenes 8873
                                          3,3'-Dichlorobenzidine 11
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