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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3,3'-Dichlorobenzidine
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Accession:CHEBI:82315 term browser browse the term
Definition:A monochlorobenzene that has formula C12H10Cl2N2.
Synonyms:related_synonym: Formula=C12H10Cl2N2;   InChI=1S/C12H10Cl2N2/c13-9-5-7(1-3-11(9)15)8-2-4-12(16)10(14)6-8/h1-6H,15-16H2;   InChIKey=HUWXDEQWWKGHRV-UHFFFAOYSA-N;   SMILES=Nc1ccc(cc1Cl)-c1ccc(N)c(Cl)c1
 xref: CAS:91-94-1;   KEGG:C19225
 xref_mesh: MESH:D015101


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3,3'-Dichlorobenzidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP 3,3'-Dichlorobenzidine binds to and results in decreased activity of AHR protein CTD PMID:2555073 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ar androgen receptor multiple interactions
affects localization		 ISO 3,3'-Dichlorobenzidine analog binds to and results in increased activity of AR protein; 3,3'-Dichlorobenzidine binds to and results in decreased activity of AR protein; 3,3'-Dichlorobenzidine inhibits the reaction [Metribolone results in increased activity of AR protein]
3,3'-Dichlorobenzidine analog affects the localization of AR protein		 CTD PMID:15950433 PMID:18324785 PMID:28478275 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression ISO 3,3'-Dichlorobenzidine affects the expression of BAX protein CTD PMID:24604609 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO 3,3'-Dichlorobenzidine affects the expression of BCL2 protein CTD PMID:24604609 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases activity ISO 3,3'-Dichlorobenzidine results in increased activity of CASP3 protein CTD PMID:24604609 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO 3,3'-Dichlorobenzidine results in increased activity of CASP9 protein CTD PMID:24604609 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases metabolic processing
multiple interactions		 ISO
EXP		 CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine
lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine]		 CTD PMID:9310344 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 affects expression ISO 3,3'-Dichlorobenzidine affects the expression of HSPA4 protein CTD PMID:24604609 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Por cytochrome p450 oxidoreductase affects metabolic processing EXP POR protein affects the metabolism of 3,3'-Dichlorobenzidine CTD PMID:3130202 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 affects expression ISO 3,3'-Dichlorobenzidine affects the expression of RUVBL2 protein CTD PMID:24604609 NCBI chr 1:95,902,014...95,915,364
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects expression ISO 3,3'-Dichlorobenzidine affects the expression of YWHAQ protein CTD PMID:24604609 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      molecular entity 20054
        polyatomic entity 19984
          molecule 19845
            cyclic compound 19610
              ring assembly 8080
                biphenyls 6030
                  3,3'-Dichlorobenzidine 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic molecule 19822
                              organic cyclic compound 19575
                                carbocyclic compound 18521
                                  benzenoid aromatic compound 17760
                                    benzenes 17560
                                      chlorobenzenes 13872
                                        monochlorobenzenes 9886
                                          3,3'-Dichlorobenzidine 11
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