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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3,3'-Dichlorobenzidine
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Accession:CHEBI:82315 term browser browse the term
Definition:A monochlorobenzene that has formula C12H10Cl2N2.
Synonyms:related_synonym: Formula=C12H10Cl2N2;   InChI=1S/C12H10Cl2N2/c13-9-5-7(1-3-11(9)15)8-2-4-12(16)10(14)6-8/h1-6H,15-16H2;   InChIKey=HUWXDEQWWKGHRV-UHFFFAOYSA-N;   SMILES=Nc1ccc(cc1Cl)-c1ccc(N)c(Cl)c1
 xref: CAS:91-94-1;   KEGG:C19225
 xref_mesh: MESH:D015101


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3,3'-Dichlorobenzidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP 3,3'-Dichlorobenzidine binds to and results in decreased activity of AHR protein CTD PMID:2555073 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ar androgen receptor multiple interactions
affects localization
ISO 3,3'-Dichlorobenzidine analog binds to and results in increased activity of AR protein; 3,3'-Dichlorobenzidine binds to and results in decreased activity of AR protein; 3,3'-Dichlorobenzidine inhibits the reaction [Metribolone results in increased activity of AR protein]
3,3'-Dichlorobenzidine analog affects the localization of AR protein
CTD PMID:15950433 PMID:18324785 PMID:28478275 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression ISO 3,3'-Dichlorobenzidine affects the expression of BAX protein CTD PMID:24604609 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO 3,3'-Dichlorobenzidine affects the expression of BCL2 protein CTD PMID:24604609 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases activity ISO 3,3'-Dichlorobenzidine results in increased activity of CASP3 protein CTD PMID:24604609 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO 3,3'-Dichlorobenzidine results in increased activity of CASP9 protein CTD PMID:24604609 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases metabolic processing
multiple interactions
ISO
EXP
CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine
lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine]
CTD PMID:9310344 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 affects expression ISO 3,3'-Dichlorobenzidine affects the expression of HSPA4 protein CTD PMID:24604609 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Por cytochrome p450 oxidoreductase affects metabolic processing EXP POR protein affects the metabolism of 3,3'-Dichlorobenzidine CTD PMID:3130202 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 affects expression ISO 3,3'-Dichlorobenzidine affects the expression of RUVBL2 protein CTD PMID:24604609 NCBI chr 1:95,902,014...95,915,364
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects expression ISO 3,3'-Dichlorobenzidine affects the expression of YWHAQ protein CTD PMID:24604609 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      molecular entity 19811
        polyatomic entity 19732
          molecule 19583
            cyclic compound 19387
              ring assembly 8055
                biphenyls 6010
                  3,3'-Dichlorobenzidine 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                carbocyclic compound 18309
                                  benzenoid aromatic compound 17453
                                    benzenes 17233
                                      chlorobenzenes 13608
                                        monochlorobenzenes 9752
                                          3,3'-Dichlorobenzidine 11
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