CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2,2-Bis(bromomethyl)propane-1,3-diol
Accession: CHEBI:82294
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Definition: A primary alcohol that has formula C5H10Br2O2.
Synonyms: related_synonym: Formula=C5H10Br2O2; InChI=1S/C5H10Br2O2/c6-1-5(2-7,3-8)4-9/h8-9H,1-4H2; InChIKey=CHUGKEQJSLOLHL-UHFFFAOYSA-N; Pentaerythritol dibromide; SMILES=OCC(CO)(CBr)CBr
xref: CAS:3296-90-0; KEGG:C19199
xref_mesh: MESH:C060080
G
Acsm1
acyl-CoA synthetase medium-chain family member 1
decreases expression
ISO
2,2-bis(bromomethyl)-1,3-propanediol results in decreased expression of ACSM1 mRNA
CTD
PMID:17311802
NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
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Ces1d
carboxylesterase 1D
increases expression
ISO
2,2-bis(bromomethyl)-1,3-propanediol results in increased expression of CES1 mRNA
CTD
PMID:17311802
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Ephx1
epoxide hydrolase 1
increases expression
ISO
2,2-bis(bromomethyl)-1,3-propanediol results in increased expression of EPHX1 mRNA
CTD
PMID:17311802
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Kras
KRAS proto-oncogene, GTPase
increases mutagenesis
ISO
2,2-bis(bromomethyl)-1,3-propanediol results in increased mutagenesis of KRAS gene
CTD
PMID:14713543
NCBI chr 4:178,185,418...178,218,484
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
ISO
2,2-bis(bromomethyl)-1,3-propanediol results in increased expression of NFE2L2 protein
CTD
PMID:22019925
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression
ISO
2,2-bis(bromomethyl)-1,3-propanediol results in decreased expression of NQO1 mRNA
CTD
PMID:17311802
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Ugt2b7
UDP glucuronosyltransferase family 2 member B7
increases glucuronidation
ISO
UGT2B7 protein results in increased glucuronidation of 2,2-bis(bromomethyl)-1,3-propanediol
CTD
PMID:20200232
NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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