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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Antimony trioxide
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Accession:CHEBI:82289 term browser browse the term
Synonyms:xref: CAS:1309-64-4;   KEGG:C19192
 xref_mesh: MESH:C037554


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Antimony trioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO antimony trioxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO antimony trioxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO antimony trioxide results in increased expression of ITGAM protein CTD PMID:16112521 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity
ISO [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein; Buthionine Sulfoximine promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]; Glutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]
MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein]
CTD PMID:16112521 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO antimony trioxide results in increased cleavage of PARP1 protein
Glutathione deficiency promotes the reaction [antimony trioxide results in increased cleavage of PARP1 protein]
CTD PMID:16112521 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pml PML nuclear body scaffold affects localization
multiple interactions
increases degradation
ISO antimony trioxide affects the localization of PML protein
antimony trioxide promotes the reaction [SUMO1 protein binds to PML protein]
antimony trioxide results in increased degradation of PML protein mutant form
CTD PMID:9834237 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Rara retinoic acid receptor, alpha increases degradation ISO antimony trioxide results in increased degradation of RARA protein mutant form CTD PMID:9834237 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects localization
multiple interactions
ISO antimony trioxide affects the localization of SUMO1 protein
antimony trioxide promotes the reaction [SUMO1 protein binds to PML protein]
CTD PMID:9834237 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19791
    chemical entity 19791
      atom 19788
        nonmetal atom 19663
          carbon atom 19568
            organic molecular entity 19568
              Antimony trioxide 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19791
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19676
                    p-block element atom 19676
                      carbon group element atom 19579
                        carbon atom 19568
                          organic molecular entity 19568
                            Antimony trioxide 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.