Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Clofop
go back to main search page
Accession:CHEBI:82195 term browser browse the term
Definition:An aromatic ether that has formula C15H13ClO4.
Synonyms:related_synonym: Formula=C15H13ClO4;   InChI=1S/C15H13ClO4/c1-10(15(17)18)19-13-3-2-4-14(9-13)20-12-7-5-11(16)6-8-12/h2-10H,1H3,(H,17,18);   InChIKey=MVJSHNOLKGWVHY-UHFFFAOYSA-N;   SMILES=CC(Oc1cccc(Oc2ccc(Cl)cc2)c1)C(O)=O
 xref: CAS:26129-32-8;   KEGG:C19070
 xref_mesh: MESH:C006012


show annotations for term's descendants           Sort by:
 
Clofop term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of AADAC mRNA CTD PMID:16197558 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ABHD3 mRNA CTD PMID:16197558 NCBI chr18:1,892,413...1,946,840
Ensembl chr18:1,892,413...1,946,840
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ACADM mRNA CTD PMID:16197558 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ACADVL mRNA CTD PMID:16197558 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ACSL1 mRNA CTD PMID:16197558 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:18513333 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adipor1 adiponectin receptor 1 decreases expression ISO fenofibric acid results in decreased expression of ADIPOR1 protein CTD PMID:16023994 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO AKR1B1 protein results in increased reduction of fenofibric acid CTD PMID:27599626 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
decreases activity
ISO fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
fenofibric acid results in decreased activity of AKR1B10 protein; fenofibric acid results in decreased activity of AKR1B10 protein mutant form
CTD PMID:18325492 PMID:19028477 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases reduction ISO AKR1C2 protein results in increased reduction of fenofibric acid CTD PMID:27599626 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases reduction ISO AKR1C3 protein results in increased reduction of fenofibric acid CTD PMID:27599626 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ANGPTL4 mRNA CTD PMID:16197558 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
decreases expression
EXP [fenofibric acid co-treated with Dexamethasone] results in increased expression of APOA1 mRNA; [fenofibric acid co-treated with Tretinoin] results in increased expression of APOA1 mRNA; fenofibric acid inhibits the reaction [Dexamethasone results in increased expression of APOA1 mRNA]; fenofibric acid inhibits the reaction [Tretinoin results in increased expression of APOA1 mRNA]
fenofibric acid results in decreased expression of APOA1 mRNA
CTD PMID:7556148 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP fenofibric acid results in decreased expression of APOA2 mRNA CTD PMID:7556148 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of AQP3 mRNA CTD PMID:16197558 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Ascc1 activating signal cointegrator 1 complex subunit 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ASCC1 mRNA CTD PMID:16197558 NCBI chr20:29,558,330...29,648,899
Ensembl chr20:29,558,689...29,648,893
JBrowse link
G Cat catalase multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of CAT mRNA CTD PMID:16197558 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr1 carbonyl reductase 1 increases reduction ISO CBR1 protein results in increased reduction of fenofibric acid CTD PMID:27599626 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of CEBPA mRNA CTD PMID:16197558 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:18513333 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of CPT1A mRNA CTD PMID:16197558 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases activity
increases expression
ISO fenofibric acid results in increased activity of CYP2C8 protein
fenofibric acid results in increased expression of CYP2C8 mRNA; fenofibric acid results in increased expression of CYP2C8 protein
CTD PMID:15771232 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of FABP1 mRNA CTD PMID:16197558 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA] CTD PMID:18513333 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Gng12 G protein subunit gamma 12 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of GNG12 mRNA CTD PMID:16197558 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of HADHA mRNA CTD PMID:16197558 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of HADHB mRNA CTD PMID:16197558 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of HMGCS2 mRNA CTD PMID:16197558 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of HMOX1 mRNA CTD PMID:16197558 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ID2 mRNA CTD PMID:16197558 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of ISCA1 mRNA CTD PMID:16197558 NCBI chr17:5,281,727...5,294,386
Ensembl chr17:5,281,727...5,294,384
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of PCK1 mRNA CTD PMID:16197558 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pdzk1 PDZ domain containing 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of PDZK1 mRNA CTD PMID:16197558 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of PLIN2 mRNA CTD PMID:16197558 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding
increases activity
increases expression
multiple interactions
ISO fenofibric acid binds to PPARA protein
fenofibric acid results in increased activity of PPARA protein
fenofibric acid results in increased expression of PPARA mRNA
[fenofibric acid binds to PPARA protein] which results in increased expression of AADAC mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ABHD3 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ACADM mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ACADVL mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ACSL1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ANGPTL4 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of AQP3 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ASCC1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of CAT mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of CEBPA mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of CPT1A mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of FABP1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of GNG12 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of HADHA mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of HADHB mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of HMGCS2 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of HMOX1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ID2 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of ISCA1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of PCK1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of PDZK1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of PLIN2 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of SERPINE1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of SLC16A1 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of SLC25A20 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of TMEM53 mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of TXNIP mRNA; [fenofibric acid binds to PPARA protein] which results in increased expression of VNN1 mRNA; fenofibric acid results in increased activity of [PPARA protein binds to RXRA protein]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]
CTD PMID:11779144 PMID:15273253 PMID:16197558 PMID:16680075 PMID:17360982 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO fenofibric acid results in increased activity of [PPARD protein binds to RXRA protein] CTD PMID:11779144 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
increases activity
multiple interactions
ISO fenofibric acid binds to PPARG protein
fenofibric acid results in increased activity of PPARG protein
fenofibric acid results in increased activity of [PPARG protein alternative form binds to RXRA protein]
CTD PMID:11779144 PMID:15273253 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO fenofibric acid results in increased activity of [PPARA protein binds to RXRA protein]; fenofibric acid results in increased activity of [PPARD protein binds to RXRA protein]; fenofibric acid results in increased activity of [PPARG protein alternative form binds to RXRA protein] CTD PMID:11779144 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
decreases secretion
decreases expression
ISO [fenofibric acid binds to PPARA protein] which results in increased expression of SERPINE1 mRNA
fenofibric acid results in decreased secretion of SERPINE1 protein
fenofibric acid results in decreased expression of SERPINE1 mRNA
CTD PMID:10364093 PMID:16197558 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of SLC16A1 mRNA CTD PMID:16197558 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of SLC25A20 mRNA CTD PMID:16197558 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]] CTD PMID:17360982 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of TGFB1 mRNA] CTD PMID:18513333 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tmem53 transmembrane protein 53 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of TMEM53 mRNA CTD PMID:16197558 NCBI chr 5:136,112,417...136,127,976
Ensembl chr 5:136,112,417...136,127,976
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of TXNIP mRNA CTD PMID:16197558 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO fenofibric acid results in increased expression of UGT1A1 mRNA CTD PMID:15771232 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vnn1 vanin 1 multiple interactions ISO [fenofibric acid binds to PPARA protein] which results in increased expression of VNN1 mRNA CTD PMID:16197558 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      application 19412
        pesticide 16581
          herbicide 11815
            phenoxy herbicide 214
              Clofop 47
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            heteroorganic entity 19216
                              organochalcogen compound 18966
                                organooxygen compound 18893
                                  ether 16897
                                    aromatic ether 16193
                                      Clofop 47
paths to the root