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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:rac-1,2-dichloropropane
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Accession:CHEBI:82163 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-1,2-dichloropropane. It is used as a fumigant to control nematodes in soil and insects in stored grain.
Synonyms:related_synonym: (+-)-1,2-dichloropropane;   (2RS)-1,2-dichloropropane;   rac-(2R)-1,2-dichloropropane;   rac-1,2-DCP;   rac-CH3CHClCH2Cl;   rac-alpha,beta-dichloropropane;   rac-alpha,beta-propylene dichloride;   rac-dichloro-1,2 propane;   rac-propylene dichloride
 xref: CAS:78-87-5;   KEGG:C19034
 xref_mesh: MESH:C004765
 xref: PMID:21070183;   PMID:28527381;   PMID:29863124;   PMID:29973469;   PMID:30240022;   PPDB:1191;   Pesticides:1\,2-dichloropropane;   Reaxys:1718880


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rac-1,2-dichloropropane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression
multiple interactions		 ISO propylene dichloride results in decreased expression of ACAT1 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of ACAT1 protein]		 CTD PMID:32435916 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions
increases expression		 ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ACOT2 protein] CTD PMID:32435916 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Aicda activation-induced cytidine deaminase affects expression ISO propylene dichloride affects the expression of AICDA mRNA CTD PMID:30452740 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression
multiple interactions		 ISO propylene dichloride results in increased expression of ALDH1B1 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ALDH1B1 protein]		 CTD PMID:32435916 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Car3 carbonic anhydrase 3 decreases expression
multiple interactions		 ISO propylene dichloride results in decreased expression of CAR3 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CAR3 protein]		 CTD PMID:32435916 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression
multiple interactions		 ISO propylene dichloride results in decreased expression of CES3B protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CES3B protein]		 CTD PMID:32435916 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation ISO CYP2E1 protein results in increased oxidation of propylene dichloride CTD PMID:1664256 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression
multiple interactions		 ISO propylene dichloride results in increased expression of ECH1 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ECH1 protein]		 CTD PMID:32435916 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase decreases expression
multiple interactions		 ISO propylene dichloride results in decreased expression of FTCD protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of FTCD protein]		 CTD PMID:32435916 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression
multiple interactions		 ISO propylene dichloride results in increased expression of FTH1 protein
1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased expression of FTH1 protein]		 CTD PMID:32435916 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression
multiple interactions		 ISO propylene dichloride results in increased expression of FTL1 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of FTL1 protein]		 CTD PMID:32435916 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP propylene dichloride results in increased expression of GPT protein CTD PMID:1980407 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions		 ISO propylene dichloride results in increased expression of GSTM1 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of GSTM1 protein]		 CTD PMID:32435916 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
multiple interactions		 ISO propylene dichloride results in increased phosphorylation of H2AX protein
1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Disulfiram inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Fomepizole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]		 CTD PMID:28300663 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Inmt indolethylamine N-methyltransferase multiple interactions
decreases expression		 ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of INMT protein] CTD PMID:32435916 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493 		JBrowse link
G Krt8 keratin 8 decreases expression
multiple interactions		 ISO propylene dichloride results in decreased expression of KRT8 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of KRT8 protein]		 CTD PMID:32435916 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Otc ornithine transcarbamylase increases activity EXP propylene dichloride results in increased activity of OTC protein CTD PMID:2744274 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
G Rgn regucalcin multiple interactions
decreases expression		 ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of RGN protein] CTD PMID:32435916 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO propylene dichloride results in increased expression of TNF mRNA CTD PMID:30452740 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 affects localization ISO propylene dichloride affects the localization of TP53BP1 protein CTD PMID:28300663 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Ubp1 upstream binding protein 1 decreases expression
multiple interactions		 ISO propylene dichloride results in decreased expression of UBP1 protein
1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of UBP1 protein]		 CTD PMID:32435916 NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19757
    role 19730
      application 19563
        agrochemical 15669
          rac-1,2-dichloropropane 21
            D-D mixture 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19757
    subatomic particle 19755
      composite particle 19755
        hadron 19755
          baryon 19755
            nucleon 19755
              atomic nucleus 19755
                atom 19755
                  main group element atom 19703
                    main group molecular entity 19703
                      s-block molecular entity 19557
                        hydrogen molecular entity 19550
                          hydrides 19031
                            organic hydride 18631
                              organic fundamental parent 18631
                                hydrocarbon 18376
                                  halohydrocarbon 15375
                                    haloalkane 12093
                                      chloroalkane 9309
                                        1,2-dichloropropane 21
                                          (S)-1,2-dichloropropane 21
                                            rac-1,2-dichloropropane 21
                                              D-D mixture 0
paths to the root