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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Mipafox
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Accession:CHEBI:82142 term browser browse the term
Definition:A phosphoramide that has formula C6H16FN2OP.
Synonyms:related_synonym: Formula=C6H16FN2OP;   InChI=1S/C6H16FN2OP/c1-5(2)8-11(7,10)9-6(3)4/h5-6H,1-4H3,(H2,8,9,10);   InChIKey=UOSHUBFBCPGQAY-UHFFFAOYSA-N;   SMILES=CC(C)NP(F)(=O)NC(C)C
 xref: CAS:371-86-8;   KEGG:C19008
 xref_mesh: MESH:C005238
 xref: PPDB:2871


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Mipafox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
Metoclopramide inhibits the reaction [mipafox binds to and results in decreased activity of ACHE protein]; Metoclopramide inhibits the reaction [mipafox results in decreased activity of ACHE protein]; mipafox binds to and results in decreased activity of ACHE protein CTD PMID:7713347 PMID:9268605 PMID:9515941 PMID:14635269 PMID:15052610 PMID:16193528 PMID:16766477 PMID:24395470 PMID:25743373 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
ISO Metoclopramide inhibits the reaction [mipafox binds to and results in decreased activity of BCHE protein]; mipafox binds to and results in decreased activity of BCHE protein; mipafox inhibits the reaction [BCHE protein results in increased hydrolysis of acetylthiocholine iodide]; mipafox inhibits the reaction [BCHE protein results in increased hydrolysis of phenyl valerate]
mipafox results in decreased activity of BCHE protein
CTD PMID:15052610 PMID:28299395 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO mipafox results in decreased expression of GAP43 protein CTD PMID:27939611 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO mipafox results in decreased expression of NEFH protein CTD PMID:27939611 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 multiple interactions
decreases activity
affects response to substance
ISO
EXP
mipafox inhibits the reaction [PNPLA6 protein results in increased hydrolysis of phenyl valerate]
mipafox results in decreased activity of PNPLA6 protein
PNPLA6 protein mutant form affects the susceptibility to mipafox
[Paraoxon co-treated with mipafox] results in decreased activity of PNPLA6 protein
CTD PMID:3714122 PMID:7713347 PMID:8486913 PMID:9268605 PMID:16766477 PMID:19620706 PMID:20382209 PMID:20603202 PMID:24395470 PMID:24413757 PMID:27117976 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Syn1 synapsin I decreases expression ISO mipafox results in decreased expression of SYN1 protein CTD PMID:27939611 NCBI chr  X:1,321,315...1,379,202
Ensembl chr  X:1,321,315...1,379,198
JBrowse link
G Syp synaptophysin decreases expression ISO mipafox results in decreased expression of SYP protein CTD PMID:27939611 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      application 19406
        solvent 16547
          phosphoric acid 7954
            phosphoramide 1017
              Mipafox 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      chalcogen 19387
                        oxygen atom 19350
                          oxygen molecular entity 19350
                            hydroxides 19076
                              oxoacid 18275
                                pnictogen oxoacid 10312
                                  phosphorus oxoacid 9234
                                    phosphoric acids 7954
                                      phosphoric acid 7954
                                        phosphoramide 1017
                                          Mipafox 7
paths to the root