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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:leptophos
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Accession:CHEBI:82137 term browser browse the term
Definition:An organic thiophosphate that has formula C13H10BrCl2O3PS.
Synonyms:exact_synonym: rac-O-(4-bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate
 related_synonym: (RS)-O-(4-bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate;   Abar;   Formula=C13H10BrCl2O2PS;   Fosvel;   K62-105;   MBCP;   NK 711;   OMS 1438;   Oleophosvel;   Phosvel;   VCS 5-D;   VCS-506;   Velsicol 506;   Velsicol VCS-506;   racemic leptophos
 xref: AGR:IND89026816;   CAS:21609-90-5;   FooDB:FDB008471;   HMDB:HMDB0031798;   KEGG:C19003
 xref_mesh: MESH:D010773
 xref: PMID:12537969;   PMID:12742374;   PMID:15492452;   PMID:21152278;   PMID:21428349;   PMID:21432420;   PMID:2431660;   PMID:2473232;   PMID:2481746;   PMID:318517;   PMID:4841433;   PMID:6188603;   PMID:64240;   PMID:72768;   PMID:7685784;   PMID:8720167;   PMID:91399;   PMID:91400;   PMID:9198007;   PPDB:1520;   Pesticides:leptophos;   Reaxys:2152663;   Wikipedia:Leptophos



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leptophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Leptophos metabolite results in decreased activity of ACHE protein; Leptophos results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [Leptophos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO Leptophos results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO Leptophos results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Leptophos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Leptophos results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      biological role 19773
        aetiopathogenetic role 19050
          neurotoxin 17844
            leptophos 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            heteroorganic entity 19301
                              organophosphorus compound 8205
                                organophosphorus pesticide 4217
                                  organophosphorus insecticide 4217
                                    organothiophosphate insecticide 982
                                      leptophos 6
paths to the root