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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
Endrin results in increased expression of ADIPOQ mRNA |
CTD |
PMID:34801515 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Alk |
ALK receptor tyrosine kinase |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA |
CTD |
PMID:28263720 |
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NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Endrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] |
CTD |
PMID:26022396 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Bhlha15 |
basic helix-loop-helix family, member a15 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA |
CTD |
PMID:28263720 |
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NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases activity decreases expression increases expression |
ISO |
Endrin results in decreased activity of CEBPA protein Endrin results in decreased expression of CEBPA protein Endrin results in increased expression of CEBPA mRNA |
CTD |
PMID:10385688 PMID:34801515 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
Endrin results in increased expression of CEBPB mRNA |
CTD |
PMID:34801515 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
multiple interactions increases expression |
ISO |
MK 2206 inhibits the reaction [Endrin results in increased expression of CEBPD mRNA]; Sirolimus inhibits the reaction [Endrin results in increased expression of CEBPD mRNA] |
CTD |
PMID:34801515 |
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NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Cycs |
cytochrome c, somatic |
increases reduction |
ISO |
Endrin results in increased reduction of CYCS protein |
CTD |
PMID:12049837 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Endrin results in increased expression of CYP26A1 mRNA AGN 193109 inhibits the reaction [Endrin results in increased expression of CYP26A1 mRNA] |
CTD |
PMID:15589975 |
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NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression |
ISO |
Endrin results in increased expression of CYP2B6 protein |
CTD |
PMID:15548381 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases expression |
ISO |
Endrin results in increased expression of CYP3A4 protein |
CTD |
PMID:15548381 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Epha3 |
Eph receptor A3 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA |
CTD |
PMID:28263720 |
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NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
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G |
Epha8 |
Eph receptor A8 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA |
CTD |
PMID:28263720 |
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NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases activity |
ISO |
Endrin binds to and results in increased activity of ESR1 protein Endrin results in increased activity of ESR1 protein |
CTD |
PMID:15064155 PMID:16626760 PMID:26022396 PMID:26139245 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions increases activity |
ISO |
Endrin binds to and results in decreased activity of ESR2 protein Endrin results in increased activity of ESR2 protein |
CTD |
PMID:16626760 PMID:26139245 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Endrin results in increased expression of FASN mRNA |
CTD |
PMID:34801515 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Gfra1 |
GDNF family receptor alpha 1 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA |
CTD |
PMID:28263720 |
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NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
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G |
Gsr |
glutathione-disulfide reductase |
increases activity |
EXP |
Endrin results in increased activity of GSR protein |
CTD |
PMID:2276583 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
EXP |
Endrin results in increased expression of HSP90AA1 mRNA alternative form |
CTD |
PMID:8792849 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA |
CTD |
PMID:28263720 |
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NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Lrrc2 |
leucine rich repeat containing 2 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA |
CTD |
PMID:28263720 |
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NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185
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G |
Mertk |
MER proto-oncogene, tyrosine kinase |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA |
CTD |
PMID:28263720 |
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NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
affects activity |
ISO |
Endrin affects the activity of NFKB1 protein |
CTD |
PMID:10385688 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions increases activity |
ISO |
Endrin binds to and results in increased activity of NR1I2 protein Endrin results in increased activity of NR1I2 protein |
CTD |
PMID:15548381 PMID:16054614 PMID:21115097 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
Endrin results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
increases activity |
ISO |
Endrin results in increased activity of NR3C1 protein |
CTD |
PMID:19927138 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Ntrk1 |
neurotrophic receptor tyrosine kinase 1 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA |
CTD |
PMID:28263720 |
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NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
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G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA |
CTD |
PMID:28263720 |
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NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA |
CTD |
PMID:28263720 |
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NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
Endrin inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein] |
CTD |
PMID:26022396 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Plxnd1 |
plexin D1 |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA |
CTD |
PMID:28263720 |
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NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression increases expression multiple interactions |
ISO |
Endrin results in decreased expression of PPARG protein Endrin results in increased expression of PPARG mRNA MK 2206 inhibits the reaction [Endrin results in increased expression of PPARG mRNA]; Sirolimus inhibits the reaction [Endrin results in increased expression of PPARG mRNA] |
CTD |
PMID:10385688 PMID:34801515 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Rarb |
retinoic acid receptor, beta |
increases expression |
ISO |
Endrin results in increased expression of RARB mRNA |
CTD |
PMID:15589975 |
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NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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G |
Rarg |
retinoic acid receptor, gamma |
increases expression increases activity |
ISO |
Endrin results in increased expression of RARG mRNA Endrin results in increased activity of RARG protein |
CTD |
PMID:15589975 PMID:30639747 |
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NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
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G |
Ret |
ret proto-oncogene |
multiple interactions |
ISO |
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA |
CTD |
PMID:28263720 |
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NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
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G |
Rora |
RAR-related orphan receptor A |
affects binding |
ISO |
Endrin binds to RORA protein |
CTD |
PMID:32278787 |
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NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
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G |
Slc2a4 |
solute carrier family 2 member 4 |
increases expression |
ISO |
Endrin results in increased expression of SLC2A4 mRNA |
CTD |
PMID:34801515 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Tp53 |
tumor protein p53 |
affects response to substance |
ISO |
TRP53 protein affects the susceptibility to Endrin |
CTD |
PMID:10802220 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Vip |
vasoactive intestinal peptide |
multiple interactions |
EXP |
Endrin inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP] |
CTD |
PMID:2467674 |
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NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
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