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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinoxyfen
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Accession:CHEBI:82040 term browser browse the term
Definition:A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals.
Synonyms:exact_synonym: 5,7-dichloro-4-(4-fluorophenoxy)quinoline
 related_synonym: 5,7-dichloro-4-quinolyl 4-fluorophenyl ether;   DE 795;   Formula=C15H8Cl2FNO;   HSDB 7946;   InChI=1S/C15H8Cl2FNO/c16-9-7-12(17)15-13(8-9)19-6-5-14(15)20-11-3-1-10(18)2-4-11/h1-8H;   InChIKey=WRPIRSINYZBGPK-UHFFFAOYSA-N;   SMILES=Fc1ccc(Oc2ccnc3cc(Cl)cc(Cl)c23)cc1
 xref: CAS:124495-18-7;   KEGG:C18892
 xref_mesh: MESH:C470613
 xref: PMID:21337673;   PMID:23175987;   PMID:23182285;   PMID:23534560;   PMID:24674876;   PMID:25306363;   PPDB:580;   Patent:EP2308303;   Pesticides:quinoxyfen;   Reaxys:11339818


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quinoxyfen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO quinoxyfen inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21310686 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Cat catalase affects binding ISO quinoxyfen binds to CAT protein CTD PMID:32278787 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO quinoxyfen results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO quinoxyfen results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Ins2 insulin 2 multiple interactions ISO quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein CTD PMID:25028461 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO quinoxyfen results in increased expression of PPARG mRNA CTD PMID:32473317 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO quinoxyfen results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO quinoxyfen binds to SHBG protein CTD PMID:32278787 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    role 19732
      application 19423
        pesticide 16670
          antifungal agrochemical 8184
            quinoxyfen 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19596
                        carbon atom 19586
                          organic molecular entity 19586
                            organic molecule 19519
                              organic cyclic compound 19349
                                carbocyclic compound 18304
                                  benzenoid aromatic compound 17416
                                    benzenes 17188
                                      fluorobenzenes 1772
                                        monofluorobenzenes 1432
                                          quinoxyfen 11
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