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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinoxyfen
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Accession:CHEBI:82040 term browser browse the term
Definition:A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals.
Synonyms:exact_synonym: 5,7-dichloro-4-(4-fluorophenoxy)quinoline
 related_synonym: 5,7-dichloro-4-quinolyl 4-fluorophenyl ether;   DE 795;   Formula=C15H8Cl2FNO;   HSDB 7946;   InChI=1S/C15H8Cl2FNO/c16-9-7-12(17)15-13(8-9)19-6-5-14(15)20-11-3-1-10(18)2-4-11/h1-8H;   InChIKey=WRPIRSINYZBGPK-UHFFFAOYSA-N;   SMILES=Fc1ccc(Oc2ccnc3cc(Cl)cc(Cl)c23)cc1
 xref: CAS:124495-18-7;   KEGG:C18892
 xref_mesh: MESH:C470613
 xref: PMID:21337673;   PMID:23175987;   PMID:23182285;   PMID:23534560;   PMID:24674876;   PMID:25306363;   PPDB:580;   Patent:EP2308303;   Pesticides:quinoxyfen;   Reaxys:11339818



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quinoxyfen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [quinoxyfen co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased secretion of ADIPOQ protein CTD PMID:34323617 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ar androgen receptor multiple interactions ISO quinoxyfen inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21310686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Cat catalase affects binding ISO quinoxyfen binds to CAT protein CTD PMID:32278787 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [quinoxyfen co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CIDEC mRNA
[quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA
CTD PMID:34323617 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased expression of CYP3A4 mRNA CTD PMID:25028461 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO quinoxyfen results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO quinoxyfen results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [quinoxyfen co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA CTD PMID:34323617 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Ins2 insulin 2 multiple interactions ISO quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]
[quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA
CTD PMID:32473317 PMID:34323617 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein CTD PMID:25028461 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [quinoxyfen co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PLIN1 mRNA CTD PMID:34323617 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO quinoxyfen results in increased expression of PPARG mRNA CTD PMID:32473317 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO quinoxyfen results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A multiple interactions ISO [quinoxyfen co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SDHA protein
[quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein
CTD PMID:34323617 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO quinoxyfen binds to SHBG protein CTD PMID:32278787 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Tf transferrin multiple interactions ISO [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in decreased expression of SDHA protein; [quinoxyfen co-treated with Biotin co-treated with Pantothenic Acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Thyroxine co-treated with TF protein] results in increased expression of CIDEC mRNA CTD PMID:34323617 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 20072
    role 20026
      application 19773
        pesticide 17338
          antifungal agrochemical 8783
            quinoxyfen 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    p-block element atom 19974
                      carbon group element atom 19903
                        carbon atom 19896
                          organic molecular entity 19896
                            organic molecule 19844
                              organic cyclic compound 19605
                                carbocyclic compound 18563
                                  benzenoid aromatic compound 17816
                                    benzenes 17624
                                      fluorobenzenes 1801
                                        monofluorobenzenes 1457
                                          quinoxyfen 18
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