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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propamocarb
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Accession:CHEBI:82033 term browser browse the term
Definition:A carbamate ester that is the propyl ester of 3-(dimethylamino)propylcarbamic acid. It is a systemic fungicide, used (normally as the hydrochloride salt) for the control of soil, root and leaf diseases caused by oomycetes, particularly Phytophthora and Pythium species.
Synonyms:related_synonym: Formula=C9H20N2O2;   InChI=1S/C9H20N2O2/c1-4-8-13-9(12)10-6-5-7-11(2)3/h4-8H2,1-3H3,(H,10,12);   InChIKey=WZZLDXDUQPOXNW-UHFFFAOYSA-N;   Propyl (3-(dimethylamino)propyl)carbamate;   SMILES=CCCOC(=O)NCCCN(C)C;   propamocarbe;   propyl 3-(dimethylamino)propylcarbamate;   propyl N-[3-(dimethylamino)propyl]carbamate
 xref: CAS:24579-73-5;   KEGG:C18885
 xref_mesh: MESH:C033205
 xref: PMID:14985943;   PMID:15204535;   PMID:22699710;   PMID:24791956;   PPDB:1546;   Patent:BE708057;   Patent:EP1254894;   Patent:US3649674;   Pesticides:propamocarb;   Reaxys:2080745;   Wikipedia:Propamocarb


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propamocarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO propamocarb results in decreased expression of ACACA mRNA CTD PMID:29137890 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ache acetylcholinesterase decreases expression ISO propamocarb results in decreased expression of ACHE protein CTD PMID:30251769 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acly ATP citrate lyase decreases expression ISO propamocarb results in decreased expression of ACLY mRNA CTD PMID:29137890 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO propamocarb results in decreased expression of ACOX1 mRNA CTD PMID:29137890 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO propamocarb results in increased activity of CYP19A1 protein CTD PMID:11884232 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO propamocarb results in decreased expression of DGAT2 mRNA CTD PMID:29137890 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO propamocarb results in decreased expression of DRD2 mRNA CTD PMID:30251769 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR1 protein
propamocarb results in increased activity of ESR1 protein
CTD PMID:26812056 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
ISO [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein
propamocarb results in increased activity of ESR2 protein
CTD PMID:26812056 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO propamocarb results in decreased expression of FABP2 mRNA CTD PMID:29137890 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fasn fatty acid synthase decreases expression ISO propamocarb results in decreased expression of FASN mRNA CTD PMID:29137890 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Ffar3 free fatty acid receptor 3 decreases expression ISO propamocarb results in decreased expression of FFAR3 mRNA CTD PMID:29137890 NCBI chr 1:89,302,035...89,304,064
Ensembl chr 1:89,302,039...89,303,968
JBrowse link
G Gk glycerol kinase decreases expression ISO propamocarb results in decreased expression of GK mRNA CTD PMID:29137890 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO propamocarb results in decreased expression of GPAM mRNA CTD PMID:29137890 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Lpl lipoprotein lipase increases expression ISO propamocarb results in increased expression of LPL mRNA CTD PMID:29137890 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO propamocarb results in decreased expression of MLXIPL mRNA CTD PMID:29137890 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO propamocarb results in decreased expression of PKLR mRNA CTD PMID:29137890 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO propamocarb results in decreased expression of PPARG mRNA CTD PMID:29137890 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO propamocarb results in decreased expression of SCD1 mRNA CTD PMID:29137890 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO propamocarb results in decreased expression of SLC27A2 mRNA CTD PMID:29137890 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO propamocarb results in decreased expression of SREBF1 mRNA CTD PMID:29137890 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tph2 tryptophan hydroxylase 2 decreases expression ISO propamocarb results in decreased expression of TPH2 mRNA CTD PMID:30251769 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          propamocarb 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic ester 14077
                                        carbamate ester 7382
                                          carbamate fungicide 166
                                            propamocarb 22
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