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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propamocarb
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Accession:CHEBI:82033 term browser browse the term
Definition:A carbamate ester that is the propyl ester of 3-(dimethylamino)propylcarbamic acid. It is a systemic fungicide, used (normally as the hydrochloride salt) for the control of soil, root and leaf diseases caused by oomycetes, particularly Phytophthora and Pythium species.
Synonyms:related_synonym: Formula=C9H20N2O2;   InChI=1S/C9H20N2O2/c1-4-8-13-9(12)10-6-5-7-11(2)3/h4-8H2,1-3H3,(H,10,12);   InChIKey=WZZLDXDUQPOXNW-UHFFFAOYSA-N;   Propyl (3-(dimethylamino)propyl)carbamate;   SMILES=CCCOC(=O)NCCCN(C)C;   propamocarbe;   propyl 3-(dimethylamino)propylcarbamate;   propyl N-[3-(dimethylamino)propyl]carbamate
 xref: CAS:24579-73-5;   KEGG:C18885
 xref_mesh: MESH:C033205
 xref: PMID:14985943;   PMID:15204535;   PMID:22699710;   PMID:24791956;   PPDB:1546;   Patent:BE708057;   Patent:EP1254894;   Patent:US3649674;   Pesticides:propamocarb;   Reaxys:2080745;   Wikipedia:Propamocarb


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propamocarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO propamocarb results in decreased expression of ACACA mRNA CTD PMID:29137890 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase decreases expression ISO propamocarb results in decreased expression of ACHE protein CTD PMID:30251769 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase decreases expression ISO propamocarb results in decreased expression of ACLY mRNA CTD PMID:29137890 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO propamocarb results in decreased expression of ACOX1 mRNA CTD PMID:29137890 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO propamocarb results in increased activity of CYP19A1 protein CTD PMID:11884232 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO propamocarb results in decreased expression of DGAT2 mRNA CTD PMID:29137890 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO propamocarb results in decreased expression of DRD2 mRNA CTD PMID:30251769 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR1 protein
propamocarb results in increased activity of ESR1 protein
CTD PMID:26812056 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
ISO [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein
propamocarb results in increased activity of ESR2 protein
CTD PMID:26812056 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO propamocarb results in decreased expression of FABP2 mRNA CTD PMID:29137890 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fasn fatty acid synthase decreases expression ISO propamocarb results in decreased expression of FASN mRNA CTD PMID:29137890 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Ffar3 free fatty acid receptor 3 decreases expression ISO propamocarb results in decreased expression of FFAR3 mRNA CTD PMID:29137890 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
JBrowse link
G Gk glycerol kinase decreases expression ISO propamocarb results in decreased expression of GK mRNA CTD PMID:29137890 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO propamocarb results in decreased expression of GPAM mRNA CTD PMID:29137890 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Lpl lipoprotein lipase increases expression ISO propamocarb results in increased expression of LPL mRNA CTD PMID:29137890 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO propamocarb results in decreased expression of MLXIPL mRNA CTD PMID:29137890 NCBI chr12:21,542,964...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO propamocarb results in decreased expression of PKLR mRNA CTD PMID:29137890 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO propamocarb results in decreased expression of PPARG mRNA CTD PMID:29137890 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO propamocarb results in decreased expression of SCD1 mRNA CTD PMID:29137890 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO propamocarb results in decreased expression of SLC27A2 mRNA CTD PMID:29137890 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO propamocarb results in decreased expression of SREBF1 mRNA CTD PMID:29137890 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tph2 tryptophan hydroxylase 2 decreases expression ISO propamocarb results in decreased expression of TPH2 mRNA CTD PMID:30251769 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        xenobiotic 18452
          propamocarb 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic ester 15884
                                        carbamate ester 7445
                                          carbamate fungicide 178
                                            propamocarb 22
paths to the root